Exercise modulates the interaction between cognition and anxiety in humans
Lago TR, Hsiung A, Leitner BP, Duckworth CJ, Balderston NL, Chen KY, Grillon C, Ernst M. Exercise modulates the interaction between cognition and anxiety in humans. Cognition & Emotion 2018, 33: 863-870. PMID: 30032703, PMCID: PMC6344312, DOI: 10.1080/02699931.2018.1500445.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnxietyAttentionCognitionExerciseFemaleHealthy VolunteersHeart RateHumansMaleMemory, Short-TermConceptsAnxiety-potentiated startleAttention controlTask-relevant stimulus processingInterplay of cognitionThreat of shockThreat interferenceThreat processingWM loadWM taskMemory loadWM performanceStimulus processingCognitive abilitiesAnxiolytic effectsAnxiety disordersCognitionAnxietyType of activityProcessingFuture studiesStartleTaskHealthy volunteersParticipantsImpairmentRegulation of Human Adipose Tissue Activation, Gallbladder Size, and Bile Acid Metabolism by a β3-Adrenergic Receptor Agonist
Baskin AS, Linderman JD, Brychta RJ, McGehee S, Anflick-Chames E, Cero C, Johnson JW, O'Mara AE, Fletcher LA, Leitner BP, Duckworth CJ, Huang S, Cai H, Garraffo HM, Millo CM, Dieckmann W, Tolstikov V, Chen EY, Gao F, Narain NR, Kiebish MA, Walter PJ, Herscovitch P, Chen KY, Cypess AM. Regulation of Human Adipose Tissue Activation, Gallbladder Size, and Bile Acid Metabolism by a β3-Adrenergic Receptor Agonist. Diabetes 2018, 67: db180462. PMID: 29980535, PMCID: PMC6152342, DOI: 10.2337/db18-0462.Peer-Reviewed Original ResearchMeSH KeywordsAcetanilidesAdipose Tissue, BrownAdolescentAdrenergic beta-AgonistsAdultAgedAged, 80 and overAnimalsBile Acids and SaltsGallbladderHealthy VolunteersHumansMiceMice, Inbred C57BLMiddle AgedReceptors, Adrenergic, betaReceptors, Adrenergic, beta-3RNA, MessengerThermogenesisThiazolesYoung AdultConceptsBile acid metabolismΒ3-adrenergic receptor agonistBrown adipose tissueReceptor agonistGallbladder sizeSelective β3-AR agonistΒ3-AR agonist mirabegronPositron emission tomography/White adipose tissue lipolysisUrinary bladder relaxationΒ3-AR mRNADose-proportional increaseDoses of placeboObesity-related complicationsBAT metabolic activityEmission tomography/Adipose tissue lipolysisHuman β3-ARAcid metabolismΒ3-AR agonistConjugated bile acidsGallbladder relaxationBladder relaxationOveractive bladderHealthy men