Sandy Chang, MD, PhD

Yale College Associate Dean for Science & Quantitative Reasoning Education, Professor of Laboratory Medicine, Pathology and Molecular Biophysics and Biochemistry; Associate Director, Molecular Diagnostics Laboratory

Departments & Organizations

Laboratory Medicine: Molecular Diagnostics Laboratory

Molecular Biophysics and Biochemistry

Pathology: Experimental Pathology Graduate Program

Yale Cancer Center: Radiobiology & Radiotherapy

Yale Center for Research on Aging (Y-Age)

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Biochemistry, Quantitative Biology, Biophysics and Structural Biology (BQBS) | Molecular Medicine, Pharmacology, and Physiology

Yale Medicine

Office of Cooperative Research


Dr. Chang graduated with a BS from Yale College in 1988, and obtained his MD from Cornell University Medical College and his PhD from Rockefeller University in 1997. He completed residency in Clinical Pathology at the Brigham and Women's Hospital, and did his postdoctoral fellowship with Dr. Ronald DePinho at the Dana Farber Cancer Institute, Harvard Medical School. He was an Assistant and then Associate Professor in the Department of Genetics, MD Anderson Cancer Center, before joining the faculty at Yale Medical School as a tenured Associate Professor in 2010. Dr. Chang's research interests focuses on how telomeres, protein/DNA structures at the ends of chromosomes, are properly maintained to protect chromosome ends from engaging a DNA damage response.

Dr. Chang is the recipient of numerous awards, including those from the Howard Hughes Medical Institute, the Ellsion Medical Foundation, the Sidney Kimmel Foundation for Cancer Research, and the Ellis Benson Award from the Academy of Clinical Laboratory Physicians and Scientists. He was elected into the American Society of Clinical Investigation in 2009.

Education & Training

MD Cornell University Medical College (1997)
PhD Rockefeller University (1996)
BS Yale University (1988)
Resident Brigham & Women's Hospital
Resident Brigham & Women's Hospital
Board Certification AB of Pathology, Clinical Pathology (2003)
Board Certification AB of Pathology, Pathology (2014)

Honors & Recognition

  • Election into the American Society of Clinical InvestigationAmerican Society of Clinical Investigation (2009)

  • Ellis Benson AwardAcademy of Clinical Laboratory Physicians and Scientists (2007)

  • Sidney Kimmel Foundation for Cancer Research Scholar AwardSidney Kimmel Foundation (2005)

  • New Scholar in Aging AwardEllison Medical Foundation (2001)


  • Invited speaker to many international conferences (2002 - 2011)

    Invited speaker to many international conferences

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Contact Info

Sandy Chang, MD, PhD
Patient Care Locations
Yale Laboratory MedicineClinic Building
789 Howard Avenue

New Haven, CT 06519
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Yale Laboratory MedicineYale New Haven Hospital
20 York Street, Wing North Pavilion Fl 8th Floor Ste Apheresis

New Haven, CT 06510
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Mailing Address
Laboratory MedicinePO Box 208035
New Haven, CT 06520-8035