Jeffrey Testani, MD, MTR

Associate Professor Term; Director of Heart Failure Research, Cardiovascular Medicine

Departments & Organizations

Internal Medicine: Heart Failure Program

Yale Medicine

Office of Cooperative Research


My clinical training is as an advanced heart failure and cardiac transplantation physician with formal research training in patient oriented translational research. My research program is supported by NIH and investigator-initiated industry sources and uses techniques of both translational and clinical research to further the mechanistic understanding of cardiac-renal interactions, fluid and sodium homeostasis, and diuretic resistance in heart failure. The primary approach of my current research program is prospective mechanistic human studies in hospitalized heart failure patients, for which we have established extensive infrastructure.  Notably, we have enrolled over 700 patients and conducted over 1300 intense biospecimen collections resulting in the over 500,000 biospecimens currently housed in our biorepository at Yale. My lab has extensive expertise in biomarker research has established and maintains an extensive bioassay resource with the capability to determine an extensive range of analytes in human biological samples with complexity ranging from simple serum chemistries to complex analytes such as ultra-trace lithium by inductively coupled plasma mass spectrometry, deuterium concentration by nuclear magnetic resonance, high dimension multiplex protein assays, and large and small molecules by liquid chromatography mass spectrometry. 

Education & Training

MS University of Pennsylvania Medical School (2012)
MD University of Florida (2004)
Fellowship Hospital of the University of Pennsylvania
Research Fellowship Hospital of the University of Pennsylvania
Fellowship Hospital of the University of Pennsylvania
Residency Hospital of the University of Pennsylvania
Internship Hospital of the University of Pennsylvania
Board Certification AB of Internal Medicine, Cardiovascular Disease (2011)

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Contact Info

Jeffrey Testani, MD, MTR
Patient Care Locations
Yale CardiologyYale Physicians Building
800 Howard Avenue, Fl 2nd

New Haven, CT 06519
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Yale Cardiology175 Sherman Avenue, Ste 2nd Floor
New Haven, CT 06511
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Mailing Address
Cardiovascular MedicinePO Box 208017
New Haven, CT 06520