Current Dean's Workshops

Welcome to the Dean's Workshops website

The Dean's Workshops series brings together physicians and scientists from across the School of Medicine, the Yale medical center, and Yale University to address topics of critical importance in advancing biomedical research and patient care.

The workshops serve as a forum for new ideas and collaborations across disciplines.

Yale Genome Editing Center: Innovations in Gene Targeting

Tuesday, October 23, 2018, 1:00–5:00 p.m.
The Anlyan Center Auditorium, N143
300 Cedar St., New Haven

The ability to manipulate the mouse genome revolutionized biology. Recently, the emergence of novel genome editing technologies, particularly CRISPR/ Cas, have transformed the ease and accuracy with which we are able to alter the genomes of rodents and other organisms to effectively model and investigate physiology and pathology. The Yale Genome Editing Center (YGEC) has developed advanced rodent genome editing and reproductive assistance methods to generate customized rodent models addressing unique research questions. This Dean’s Workshop will describe the array of genome modifying technologies available to Yale investigators and detail the advancements YGEC has made to improve the speed and efficacy of creating genetically modified animals. Illustrating these advances, Yale investigators across disciplines will highlight how genome editing enhances their research.

1:00 p.m.  Welcoming remarks

Introduction to Workshop & Use of Genetic Models

Michael C. Crair, PhD William Ziegler III Professor of Neuroscience and Professor of Ophthalmology & Visual Science; Deputy Dean for Scientific Affairs (Basic Science Departments)

1:15–1:45 pm Overview of The Editing Genome Center

Timothy P. Nottoli, PhD Co-Director, Yale Genome Editing Center
 Xiaojun Xing Co-Director, Yale Genome Editing Center

1:45–2:00 pm Innovations in CRISPR Technology

William Michael Philbrick, PhD Senior Research Scientist in Medicine (Endocrinology); Director, Diabetes Endocrinology Research Center Molecular Core

2:00–3:45 pm Topics in Gene Targeting by Yale CRISPR Users

Jim Noonan, PhD Associate Professor of Genetics; Member, Kavli Institute for Neuroscience
Carrie L. Lucas, PhD Assistant Professor of Immunobiology
Sidi Chen, PhD Assistant Professor
Ruaidhri Jackson Postdoctoral Associate in Immunobiology, Flavell Lab Member
Susumu Tomita, PhD Professor of Cellular & Molecular Physiology and Neuroscience

3:45 pm Coffee, Tea, and Cookies

4:00–5:00 pm Plenary Speaker

Genetic Dissection of Neuronal Cell Types and Circuits in the Cerebral Cortex

Josh Huang, PhD Charles and Marie Robertson Professor of Neuroscience, Charles Robertson Professor of Neuroscience

5:00 pm Closing Remarks

Michael C. Crair, PhD