Discovering the 'Cytokine Language' That Activates Immune Responses
Using a new computational method based on a causal inference framework, CINEMA-OT, the Yale team studied how individual immune cells react to combinations of cytokines, or small proteins released by cells that regulate inflammation. They discovered that certain cytokines have a synergistic effect, inducing unique gene activation programs compared to their individual effects. This cryptography of cytokine signals acts as a language, instructing immune cells.
Medical School Professor Runs Through All 169 Connecticut Towns
Edward Snyder, MD, professor of laboratory medicine, doesn’t run to win, but he does run for the crown of a king. Last March, Snyder achieved a goal 16 years in the making—running races in all 169 towns in Connecticut. Those few who complete the feat are crowned as royalty by his running club.
New test shows when body is fighting a virus
A new test that measures RNA or protein molecules in human cells can accurately identify viral infection as a cause of respiratory symptoms, according to a Yale study published Dec. 21 in The Journal of Infectious Diseases. Performed with a simple nasal swab, the test could prove to be a quicker, cheaper way to diagnose respiratory viral illnesses than current methods, the researchers said.
The Jackson Laboratory highlights collaboration with Dr. Stephanie Eisenbarth in Yale Laboratory Medicine
The spleen’s mechanisms for responding to blood-borne antigens mirror those in immune responses in other sites of the body, and could potentially be harnessed to prevent life-threatening immune responses in patients requiring frequent blood transfusions.Source: The Jackson Laboratory
Dr. Stephanie Eisenbarth awarded the prestigious Ellis Benson Award from the Academy of Clinical Laboratory Physicians and Scientists for 2016.
Stephanie Eisenbarth, MD, PhD, Assistant Professor of Laboratory Medicine and Immunobiology at Yale, received the Ellis Benson Award at the June, 2016 annual meeting of the Academy of Clinical Laboratory Physicians and Scientists (ACLPS). This award is the premier award of ACLPS to a young faculty member in recognition of meritorious accomplishment in the field of laboratory medicine. The picture shows Dr. Eisenbarth receiving the Award from Academy President Marisa Marques.Source: ACLPS
Center provides researchers access to highly specialized tools
If a researcher needs highly the specialized expertise and equipment required to investigate a blood disease, where does she go? Answer: the Yale Cooperative Center of Excellence in Hematology Specialized Core Center (YCCEH). The National Institutes of Health has designated Yale as one of three universities nationwide to receive a $5 million, five-year grant. The others include the University of Washington and Indiana University.
New research helps explain why the ‘cold virus’ prefers cold temperatures
Ellen Foxman, MD, PhD, one of Laboratory Medicine’s physician-scientist trainees working with Dr. Akiko Iwasaki of the Department of Immunobiology, recently discovered that the common cold virus can reproduce more efficiently in the cooler temperature found inside the nose than at core body temperature. This finding may confirm the popular, yet contested, notion that people are more likely to catch a cold in cool-weather conditions. See the full article in Yale News and Dr. Foxman’s interview onSource: YaleNews
Dr. Christopher Tormey awarded the prestigious Ellis Benson Award from the Academy of Clinical Laboratory Physicians and Scientists for 2015
The Academy of Clinical Laboratory Physicians and Scientists (ACLPS) is the major academic society in Laboratory Medicine. The Ellis Benson Award is the premier award of ACLPS to a young faculty member in recognition of meritorious accomplishment in the field of laboratory medicine. One Award is given each year at the annual meeting. The Award honors the pioneering work of Ellis Benson in promoting research, service and teaching in laboratory medicine.