Pancreatic Cancer Risk Lower if Cysts Remain Stable for Five Years
Low-risk branch duct intraductal papillary mucinous neoplasms (IPMN) are the most common precancerous form of mucinous pancreatic cysts and once identified require regular surveillance imaging. But consensus is still forming around how long that watchful period should last. In a new study, Yale Cancer Center researchers question the health benefit of extended surveillance for patients whose cyst has not changed size for at least five years and has no worrisome features.
New Class of Oncogenic Fusions Revealed in Lung and Pancreatic Cancer
A Yale Cancer Center research team has identified novel oncogenic gene fusions in lung and pancreatic cancer, as well as sarcoma. The fusions involve RASGRF1 (an activator of RAS signaling) and promote cellular changes leading to tumor development. The research is described online ahead of print in Clinical Cancer Research.
Ignoring Back Pain Can Be a Big Pancreatic Cancer Mistake, Doctors Say
The symptoms of pancreatic cancer may be subtle, varied, or—in the early stages of the disease—non-existent. That's why "pancreatic cancer is the most lethal cancer in the human body, with overall five-year survival rates at just about seven percent despite all the advances over the past decades," according to the Mayo Clinic News Network. "There are no telltale signs for pancreatic cancer, and symptoms like weight loss, abdominal pain, jaundice, and appetite loss are nonspecific."Source: Yahoo Life
Meet Dr. Mandar Deepak Muzumdar
Dr. Muzumdar cares for patients with pancreatic cancer and explains how the Yale Pancreatic Cancer Collaborative is working together to search for novel combinations of chemotherapies and targeted therapies to further improve the treatment outcomes for pancreatic cancer.
Cell Therapy Part of The Solution to Curing Pancreatic Cancer, Experts Say
Cellular therapies will play a key role in pancreatic cancer management despite challenges thus far in applying these treatments to solid tumors, according to a panel discussion during the virtual Alliance for Cancer Gene Therapy Summit.Source: Healio
Rotating graduate students Cathy Garcia and Yanixa Quinones-Aviles complete rotations in the lab!
Congratulations to Yale MCGD students Cathy Garcia and Yanixa Quinones-Aviles for completing rotations in the lab. Cathy adroitly pushed forward our work on obesity-driven cancer, while Yanixa played a key role in our work identifying new targets in KRAS mutant cancer cells.
Rotating graduate student Jonathan Dow completes his rotation in the lab!
Congratulations to Yale MCGD student Jonathan Dow for completing his rotation in the lab! Jonathan did outstanding work developing in vitro models to study secreted factors involved in obesity-driven early pancreatic cancer progression.
Jaffar wins best poster award at inaugural Yale Cancer Biology Institute retreat!
Congratulations to postgraduate associate Jaffar Singh who won the best poster award at the inaugural Yale Cancer Biology Institute retreat! Jaffar is doing outstanding work understanding signaling mechanisms involved in regulating RAS activity in malignant and non-malignant cells.