Discovering the 'Cytokine Language' That Activates Immune Responses
Using a new computational method based on a causal inference framework, CINEMA-OT, the Yale team studied how individual immune cells react to combinations of cytokines, or small proteins released by cells that regulate inflammation. They discovered that certain cytokines have a synergistic effect, inducing unique gene activation programs compared to their individual effects. This cryptography of cytokine signals acts as a language, instructing immune cells.
Enock Teefe and José Jaime Martínez-Magaña Receive 2023 Kavli Postdoctoral Award for Academic Diversity
Enock Teefe, MD, from the laboratory of Thomas Fernandez, MD, and co-mentored by Christopher Pittenger, MD, PhD, and José Jaime Martínez-Magaña, PhD, from the laboratory of Janitza Montalvo-Ortiz, PhD, have been selected to receive the 2023 Kavli Postdoctoral Award for Academic Diversity.
In Memoriam: Gordon Murray Shepherd, MD, DPhil
We write today to share that Gordon Murray Shepherd, MD, DPhil, professor emeritus in the Department of Neuroscience, passed away on June 9, 2022. His leadership extended from research to education, and was infused with personal integrity, generosity, and great wisdom. The obituary below was prepared by Stephen Strittmatter, MD, PhD.
LaShae Nicholson and Rafael Perez Receive Kavli Postdoctoral Award for Academic Diversity
LaShae Nicholson, PhD, from the laboratory of Stephen Strittmatter, and Rafael Perez, PhD, from the laboratory of Marina Picciotto, have been selected to receive the Kavli Postdoctoral Award for Academic Diversity.
Promoting Love and Peace Across Generations through Science and Global Partnerships
Professor in the Yale Child Study Center Dr. James F. Leckman, leads a team of international scientists, scholars, and practitioners in a special journal publication that underscores the impact that early childhood development initiatives can have on promoting love and peace across generations
New Program Brings Meharry Medical Students into the ‘Yale Family’
Six students were selected from Meharry Medical College, an historically Black medical school in Nashville, in a program designed by Yale School of Medicine’s Office of Diversity, Equity and Inclusion to provide them with research experience and career advancing networking opportunities. The students will work alongside Yale faculty members and residents, begin building networks, and deepen their understanding of careers paths in psychiatry, neurosurgery, and neuroscience.
Major Gift Will Support an Innovative Brain Research Collaboration
The Swiss-based NOMIS Foundation is making a large five-year award for research into what makes the human brain unique. The research will be a collaboration between the laboratories of James P. Noonan, PhD, associate professor of genetics and of neuroscience at Yale School of Medicine, and Franck Polleux, PhD, professor of neuroscience at Columbia University and a member of that school’s Zuckerman Institute. Their combined mission is to understand the brain and mind.
Major Gift Will Endow a Program Devoted to a Fuller Understanding of How the Human Brain Works
The Thomas Kingsley Lawrence ’19 Program in Brain Research will take a multifaceted approach to understanding the higher-order functionality of the human brain and related areas. It is hoped that with the knowledge gained, novel prevention strategies, diagnostics, and therapeutics to reduce the incidence, prevalence, and recurrence of psychiatric disorders will be possible.
Yale Scientists Breach Brain Barriers to Attack Tumors
The brain is a sort of fortress, equipped with barriers designed to keep out dangerous pathogens. But protection comes at a cost: These barriers interfere with the immune system when faced with dire threats such glioblastoma, a deadly brain tumor for which there are few effective treatments.
Brain Scans, Aided by Artificial Intelligence, Reveal as Much About Us as Our DNA, Evan Morris Says.
“Brain scans, aided by artificial intelligence, reveal as much about us as our DNA,” Evan Morris recently wrote in an op-ed in Wired magazine. “Grappling with their ethical implications is vital to scientific integrity.”
Save the Dates: Kavli Institute for Neuroscience Two-day Symposium: "Cell Biology of Parkinson's Disease Genes" on April 28-29
The Kavli Institute for Neuroscience is organizing a two-day symposium, "Cell Biology of Parkinson’s Disease Genes," April 28-29, 2020. Registration required by the February 25, 2020.