Ania Jastreboff, MD, PhD

Assistant Professor of Medicine (Endocrinology) and of Pediatrics (Endocrinology)

Research Departments & Organizations

Internal Medicine: Diabetes Research Center | Endocrinology

Pediatric Endocrinology & Diabetes: Diabetes Program

Cancer Prevention and Control

Obesity Research Working Group

Research Interests

Diabetes Mellitus, Type 2; Endocrinology; Feeding and Eating Disorders; Glycemic Index; Insulin Resistance; Obesity; Pediatrics; Transition to Adult Care; Weight Loss

Research Summary

Dr. Jastreboff’s research seeks to elucidate neural mechanisms involved in obesity including neural control of eating behaviors. During her doctoral thesis work, Dr. Jastreboff became interested in understanding how metabolic perturbations, such as insulin resistance, hyperinsulinemia, leptin resistance, etc, affect neural mechanisms, which subsequently impact eating behavior and weight gain. To this end, she utilizes functional MRI to examine neural responses in obese adults and adolescents (insulin resistant and insulin sensitive) to various food cues (viewing images of high-calorie and low-calorie foods, ingestion of glucose or fructose drinks, etc). Dr. Jastreboff’s overarching goal is to conduct research that is clinically applicable for the treatment of obesity and has a clear public health impact to mitigate the obesity pandemic.

Speciailzed Terms: Obesity; Insulin resistance; Type 2 diabetes; Neural control of eating behaviors; Weight-loss maintenance; Dietary glycemic index, Diabetes technology tools, Transitions of care from pediatric to adult care

Clinical Trials

Conditions Study Title
Mental Health & Behavioral Research, Tobacco Addiction Imaging Tobacco Smoking Withdrawal using [11C]PHNO
Obesity & Weight Control Effect of liraglutide on neural responses to high fructose corn syrup in individuals with obesity
Mental Health & Behavioral Research Imaging 11B-hydroxysteroid dehydrogenase availability in vivo
Diabetes Mellitus - Type 1, Diabetes Mellitus - Type 2, Diseases of the Endocrine System Development of Agents to Diminish the Risk of Hypoglycemia-induced Brain Injury in Type 1 Diabetes
Diabetes Mellitus - Type 1, Diabetes Mellitus - Type 2, Diseases of the Endocrine System Restoring brain metabolism and function in older adult T1DM patients using an AP system
Diabetes Mellitus - Type 1, Diseases of the Endocrine System, Diseases of the Nervous System Impact of Hypoglycemia on Brain Ketone and Neurotransmitter Metabolism in Type 1 DM
Aging, Diseases of the Nervous System Glutathione and the aging brain
Addictive Behaviors, Mental Health & Behavioral Research, Tobacco Addiction Effects of Brief Training on Craving Regulation
Children's Health, Diabetes Mellitus - Type 2, Diseases of the Cardiovascular System, Diseases of the Endocrine System, Genetics - Pediatric, Obesity & Weight Control Prevalence of Carbohydrate Intolerance in Lean and Obese Children

Selected Publications

See list of PubMed publications

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