Xiaolong Zhu
Associate Research Scientist
Research & Publications
Biography
News
Coauthors
Selected Publications
- Endothelial FIS1 DeSUMOylation Protects Against Hypoxic Pulmonary HypertensionZhou X, Jiang Y, Wang Y, Fan L, Zhu Y, Chen Y, Wang Y, Zhu Y, Wang H, Pan Z, Li Z, Zhu X, Ren R, Ge Z, Lai D, Lai E, Chen T, Wang K, Liang P, Qin L, Liu C, Qiu C, Simons M, Yu L. Endothelial FIS1 DeSUMOylation Protects Against Hypoxic Pulmonary Hypertension. Circulation Research 2023, 133: 508-531. PMID: 37589160, DOI: 10.1161/circresaha.122.321200.
- Acetate controls endothelial-to-mesenchymal transitionZhu X, Wang Y, Soaita I, Lee H, Bae H, Boutagy N, Bostwick A, Zhang R, Bowman C, Xu Y, Trefely S, Chen Y, Qin L, Sessa W, Tellides G, Jang C, Snyder N, Yu L, Arany Z, Simons M. Acetate controls endothelial-to-mesenchymal transition. Cell Metabolism 2023, 35: 1163-1178.e10. PMID: 37327791, PMCID: PMC10529701, DOI: 10.1016/j.cmet.2023.05.010.
- FGFR1 SUMOylation coordinates endothelial angiogenic signaling in angiogenesisZhu X, Qiu C, Wang Y, Jiang Y, Chen Y, Fan L, Ren R, Wang Y, Chen Y, Feng Y, Zhou X, Zhu Y, Ge Z, Lai D, Qin L, Simons M, Yu L. FGFR1 SUMOylation coordinates endothelial angiogenic signaling in angiogenesis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2022, 119: e2202631119. PMID: 35733256, PMCID: PMC9245619, DOI: 10.1073/pnas.2202631119.
- Endothelium‐derived lactate is required for pericyte function and blood–brain barrier maintenanceLee H, Xu Y, Zhu X, Jang C, Choi W, Bae H, Wang W, He L, Jin S, Arany Z, Simons M. Endothelium‐derived lactate is required for pericyte function and blood–brain barrier maintenance. The EMBO Journal 2022, 41: e109890. PMID: 35243676, PMCID: PMC9058541, DOI: 10.15252/embj.2021109890.
- Endothelial CDS2 deficiency causes VEGFA-mediated vascular regression and tumor inhibitionZhao W, Cao L, Ying H, Zhang W, Li D, Zhu X, Xue W, Wu S, Cao M, Fu C, Qi H, Hao Y, Tang YC, Qin J, Zhong TP, Lin X, Yu L, Li X, Li L, Wu D, Pan W. Endothelial CDS2 deficiency causes VEGFA-mediated vascular regression and tumor inhibition. Cell Research 2019, 29: 895-910. PMID: 31501519, PMCID: PMC6889172, DOI: 10.1038/s41422-019-0229-5.
- Subretinal Transplantation of Human Amniotic Epithelial Cells in the Treatment of Autoimmune Uveitis in RatsLi J, Qiu C, Zhang Z, Yuan W, Ge Z, Tan B, Yang P, Liu J, Zhu X, Qiu C, Lai D, Guo L, Yu L. Subretinal Transplantation of Human Amniotic Epithelial Cells in the Treatment of Autoimmune Uveitis in Rats. Cell Transplantation 2018, 27: 1504-1514. PMID: 30168350, PMCID: PMC6180726, DOI: 10.1177/0963689718796196.
- Therapeutic effect of human amniotic epithelial cells in murine models of Hashimoto's thyroiditis and Systemic lupus erythematosusTan B, Yuan W, Li J, Yang P, Ge Z, Liu J, Qiu C, Zhu X, Qiu C, Lai D, Guo L, Wang L, Yu L. Therapeutic effect of human amniotic epithelial cells in murine models of Hashimoto's thyroiditis and Systemic lupus erythematosus. Cytotherapy 2018, 20: 1247-1258. PMID: 30174233, DOI: 10.1016/j.jcyt.2018.04.001.
- Nucleoside/nucleotide reverse transcriptase inhibitors attenuate angiogenesis and lymphangiogenesis by impairing receptor tyrosine kinases signalling in endothelial cellsSong L, Ding S, Ge Z, Zhu X, Qiu C, Wang Y, Lai E, Yang W, Sun Y, Chow S, Yu L. Nucleoside/nucleotide reverse transcriptase inhibitors attenuate angiogenesis and lymphangiogenesis by impairing receptor tyrosine kinases signalling in endothelial cells. British Journal Of Pharmacology 2017, 175: 1241-1259. PMID: 28910489, PMCID: PMC5866989, DOI: 10.1111/bph.14036.
- SUMOylation Negatively Regulates Angiogenesis by Targeting Endothelial NOTCH SignalingZhu X, Ding S, Qiu C, Shi Y, Song L, Wang Y, Wang Y, Li J, Wang Y, Sun Y, Qin L, Chen J, Simons M, Min W, Yu L. SUMOylation Negatively Regulates Angiogenesis by Targeting Endothelial NOTCH Signaling. Circulation Research 2017, 121: 636-649. PMID: 28760777, PMCID: PMC5581236, DOI: 10.1161/circresaha.117.310696.
- The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosisQiu C, Wang Y, Zhao H, Qin L, Shi Y, Zhu X, Song L, Zhou X, Chen J, Zhou H, Zhang H, Tellides G, Min W, Yu L. The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis. Nature Communications 2017, 8: 15426. PMID: 28569748, PMCID: PMC5461500, DOI: 10.1038/ncomms15426.