Shyoko Honiden, MD, MS
Associate Professor of Medicine (Pulmonary, Critical Care and Sleep Medicine); Director, Medical Intensive Care Unit, Internal Medicine
Research & Publications
Biography
News
Research Summary
Dr. Honiden has a wide array of interests related to the care of critically ill patients in the ICU. She has been involved in research related to the management of patients with acute liver failure, as well as studies that examine the biological effects of hyperglycemia in the ICU. She is also involved in a number of quality improvement projects, as well as ongoing clinical trials in the ICU.
Specialized Terms: Hyperglycemia in critically ill patients; Management of acute liver failure in the ICU; Therapeutic hypothermia in acute liver failure
Extensive Research Description
Ongoing clinical trials in ICU
Coauthors
Research Interests
Clinical Trials as Topic; Hyperglycemia; Hypothermia, Induced; Intensive Care Units; Lung; Liver Failure, Acute
Selected Publications
- Bedside monitoring of hypoxic ischemic brain injury using low-field, portable brain magnetic resonance imaging after cardiac arrestBeekman R, Crawford A, Mazurek MH, Prabhat AM, Chavva IR, Parasuram N, Kim N, Kim JA, Petersen N, de Havenon A, Khosla A, Honiden S, Miller PE, Wira C, Daley J, Payabvash S, Greer DM, Gilmore EJ, Kimberly W, Sheth KN. Bedside monitoring of hypoxic ischemic brain injury using low-field, portable brain magnetic resonance imaging after cardiac arrest Resuscitation 2022, 176: 150-158. PMID: 35562094, PMCID: PMC9746653, DOI: 10.1016/j.resuscitation.2022.05.002.
- Reconsidering Nutritional Support in Critically Ill PatientsKorwin A, Honiden S. Reconsidering Nutritional Support in Critically Ill Patients Seminars In Respiratory And Critical Care Medicine 2019, 40: 580-593. PMID: 31826259, DOI: 10.1055/s-0039-1697967.
- New Applications of Old Drugs as Novel Therapies in Idiopathic Pulmonary Fibrosis. Metformin, Hydroxychloroquine, and Thyroid HormoneManning EP, Losier A, Emeagwali N, Ryu C, Honiden S. New Applications of Old Drugs as Novel Therapies in Idiopathic Pulmonary Fibrosis. Metformin, Hydroxychloroquine, and Thyroid Hormone American Journal Of Respiratory And Critical Care Medicine 2019, 199: 1561-1563. PMID: 30822095, PMCID: PMC7051474, DOI: 10.1164/rccm.201809-1700rr.
- Should Physicians New to a Case Counsel Patients and Their Families to Change Course at the End of Life?Honiden S, Possick J. Should Physicians New to a Case Counsel Patients and Their Families to Change Course at the End of Life? The AMA Journal Of Ethic 2018, 20: e699-707. PMID: 30118419, DOI: 10.1001/amajethics.2018.699.
- Implementation of an ICU‐Specific Alcohol Withdrawal Syndrome Management Protocol Reduces the Need for Mechanical VentilationHeavner JJ, Akgün KM, Heavner MS, Eng CC, Drew M, Jackson P, Pritchard D, Honiden S. Implementation of an ICU‐Specific Alcohol Withdrawal Syndrome Management Protocol Reduces the Need for Mechanical Ventilation Pharmacotherapy The Journal Of Human Pharmacology And Drug Therapy 2018, 38: 701-713. PMID: 29800507, DOI: 10.1002/phar.2127.
- Antinuclear antibody testing: discordance between commercial laboratoriesAbeles AM, Gomez-Ramirez M, Abeles M, Honiden S. Antinuclear antibody testing: discordance between commercial laboratories Clinical Rheumatology 2016, 35: 1713-1718. PMID: 27044430, DOI: 10.1007/s10067-016-3241-x.
- Management of an elderly patient with respiratory failure due to double aortic archRyu C, Puchalski J, Perkins M, Honiden S. Management of an elderly patient with respiratory failure due to double aortic arch Respiratory Medicine Case Reports 2015, 17: 37-39. PMID: 27222782, PMCID: PMC4821450, DOI: 10.1016/j.rmcr.2015.12.002.
- Metabolic Management during Critical Illness: Glycemic Control in the ICUHoniden S, Inzucchi SE. Metabolic Management during Critical Illness: Glycemic Control in the ICU Seminars In Respiratory And Critical Care Medicine 2015, 36: 859-869. PMID: 26595046, DOI: 10.1055/s-0035-1565253.
- Advances and Challenges in Critical Care MedicineHoniden S, Siner JM. Advances and Challenges in Critical Care Medicine Clinics In Chest Medicine 2015, 36: xv-xvi. PMID: 26304290, DOI: 10.1016/j.ccm.2015.07.002.
- Barriers and Challenges to the Successful Implementation of an Intensive Care Unit Mobility Program Understanding Systems and Human Factors in Search for Practical SolutionsHoniden S, Connors GR. Barriers and Challenges to the Successful Implementation of an Intensive Care Unit Mobility Program Understanding Systems and Human Factors in Search for Practical Solutions Clinics In Chest Medicine 2015, 36: 431-440. PMID: 26304280, DOI: 10.1016/j.ccm.2015.05.006.
- Novel Uses of Targeted Temperature ManagementMcGinniss J, Marshall P, Honiden S. Novel Uses of Targeted Temperature Management Clinics In Chest Medicine 2015, 36: 385-400. PMID: 26304276, DOI: 10.1016/j.ccm.2015.05.011.
- The prevalence of undiagnosed diabetes mellitus and the association of baseline glycemic control on mortality in the intensive care unit: A prospective observational studyHoang QN, Pisani MA, Inzucchi S, Hu B, Honiden S. The prevalence of undiagnosed diabetes mellitus and the association of baseline glycemic control on mortality in the intensive care unit: A prospective observational study Journal Of Critical Care 2014, 29: 1052-1056. PMID: 25092614, DOI: 10.1016/j.jcrc.2014.06.007.
- Handheld Doppler to Improve Pulse Checks during Resuscitation of Putative Pulseless Electrical Activity ArrestSchonberger RB, Lampert RJ, Mandel EI, Feinleib J, Gong Z, Honiden S. Handheld Doppler to Improve Pulse Checks during Resuscitation of Putative Pulseless Electrical Activity Arrest Anesthesiology 2014, 120: 1042-1045. PMID: 24335750, PMCID: PMC3975650, DOI: 10.1097/aln.0000000000000106.
- At-Risk Drinking in the ICU… and Beyond!*Honiden S, Akgün KM. At-Risk Drinking in the ICU… and Beyond!* Critical Care Medicine 2014, 42: 988-989. PMID: 24633100, DOI: 10.1097/ccm.0000000000000094.
- Adapting To the New Consensus Guidelines for Managing Hyperglycemia During Critical Illness: the Updated Yale Insulin Infusion ProtocolShetty S, Inzucchi SE, Goldberg PA, Cooper D, Siegel MD, Honiden S. Adapting To the New Consensus Guidelines for Managing Hyperglycemia During Critical Illness: the Updated Yale Insulin Infusion Protocol Endocrine Practice 2012, 18: 363-370. PMID: 22138078, DOI: 10.4158/ep11260.or.
- The Management of the Critically Ill Obstetric PatientHoniden S, Abdel-Razeq SS, Siegel MD. The Management of the Critically Ill Obstetric Patient Journal Of Intensive Care Medicine 2011, 28: 93-106. PMID: 21841145, DOI: 10.1177/0885066611411408.
- Analytic Review: Glucose Controversies in the ICUHoniden S, Inzucchi SE. Analytic Review: Glucose Controversies in the ICU Journal Of Intensive Care Medicine 2010, 26: 135-150. PMID: 21118863, DOI: 10.1177/0885066610387892.
- Analytic Reviews: Managing the Agitated Patient in the ICU: Sedation, Analgesia, and Neuromuscular BlockadeHoniden S, Siegel MD. Analytic Reviews: Managing the Agitated Patient in the ICU: Sedation, Analgesia, and Neuromuscular Blockade Journal Of Intensive Care Medicine 2010, 25: 187-204. PMID: 20663774, DOI: 10.1177/0885066610366923.
- Obesity in the Intensive Care UnitHoniden S, McArdle JR. Obesity in the Intensive Care Unit Clinics In Chest Medicine 2009, 30: 581-599. PMID: 19700054, DOI: 10.1016/j.ccm.2009.05.007.
- Diabetes, insulin, and development of acute lung injuryHoniden S, Gong MN. Diabetes, insulin, and development of acute lung injury Critical Care Medicine 2009, 37: 2455-2464. PMID: 19531947, PMCID: PMC3103784, DOI: 10.1097/ccm.0b013e3181a0fea5.
- ICU Management of Acute Liver FailureSchilsky ML, Honiden S, Arnott L, Emre S. ICU Management of Acute Liver Failure Clinics In Chest Medicine 2009, 30: 71-87. PMID: 19186281, DOI: 10.1016/j.ccm.2008.10.001.
- Early versus late intravenous insulin administration in critically ill patientsHoniden S, Schultz A, Im SA, Nierman DM, Gong MN. Early versus late intravenous insulin administration in critically ill patients Intensive Care Medicine 2008, 34: 881. PMID: 18180902, PMCID: PMC2486366, DOI: 10.1007/s00134-007-0978-3.
- Utilization of bronchodilators in ventilated patients without obstructive airways disease.Chang LH, Honiden S, Haithcock JA, Das AM, Short KA, Nierman DM, Carson SS. Utilization of bronchodilators in ventilated patients without obstructive airways disease. Respiratory Care 2007, 52: 154-8. PMID: 17261202.
- The Effect of Diagnosis with HIV Infection on Health-Related Quality of LifeHoniden S, Sundaram V, Nease RF, Holodniy M, Lazzeroni LC, Zolopa A, Owens DK. The Effect of Diagnosis with HIV Infection on Health-Related Quality of Life Quality Of Life Research 2006, 15: 69-82. PMID: 16411032, DOI: 10.1007/s11136-005-8485-x.
- Severe hyponatremia caused by an instrasellar carotid artery aneurysm.Lee SI, Honiden S, Fain EB, Tammaro D, Schiffman FJ. Severe hyponatremia caused by an instrasellar carotid artery aneurysm. Rhode Island Medical Journal 2003, 86: 52-5. PMID: 12666279.
Clinical Trials
Conditions | Study Title |
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Women's Health; COVID-19 Inpatient; COVID-19 Outpatient | I-SPY COVID TRIAL: An Adaptive Platform Trial to Reduce Mortality and Ventilator Requirements for Critically Ill Patients |