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INFORMATION FOR

Rachel Greenup, MD, MPH

Associate Professor of Surgery (Oncology, Breast); Section Chief of Breast Surgery, Surgery

Contact Information

Rachel Greenup, MD, MPH

Research Summary

Dr. Greenup's research focuses on aligning patient-centered care with high-quality, lower cost treatment.

Extensive Research Description

Dr. Greenup's research focuses on aligning patient-centered care with high-quality, lower cost treatment. She serves on several national committees, including the Alliance in Clinical Oncology Ethics and Value Committees, the American College of Surgeons Cancer Care Delivery Task Force, the American Society of Breast Surgeons Legislative Committee, and the Editorial Board for the Annals of Surgical Oncology.

Coauthors

Research Interests

Breast Diseases

Selected Publications

  • Modifiable patient-reported factors associated with cancer-screening knowledge and participation in a community-based health assessmentFayanju O, Oyekunle T, Thomas S, Ingraham K, Fish L, Greenup R, Oeffinger K, Zafar S, Hyslop T, Hwang E, Patierno S, Barrett N. Modifiable patient-reported factors associated with cancer-screening knowledge and participation in a community-based health assessment The American Journal Of Surgery 2022 DOI: 10.1016/j.amjsurg.2022.10.059.
  • Ancillary treatment referrals and visits after breast cancer surgery in a sociodemographically diverse population.Chan V, Heller D, Berger E, Capozza S, Greenup R, Sanft T. Ancillary treatment referrals and visits after breast cancer surgery in a sociodemographically diverse population. Journal Of Clinical Oncology 2022, 40: 1533-1533. DOI: 10.1200/jco.2022.40.16_suppl.1533.
  • Treatment patterns and medical costs of metastatic breast cancer care in the United States.Jaber Chehayeb R, Hood A, Mougalian S, Lustberg M, Wang S, Greenup R, Pusztai L, Kunst N. Treatment patterns and medical costs of metastatic breast cancer care in the United States. Journal Of Clinical Oncology 2022, 40: e18834-e18834. DOI: 10.1200/jco.2022.40.16_suppl.e18834.
  • Abstract P4-10-13: Area deprivation index and rurality in relation to financial toxicity among breast cancer surgical patients - Investigating geospatial differences in risk profilesCorkum J, Zhu V, Agbafe V, Chu C, Colen J, Greenup R, Offodile A. Abstract P4-10-13: Area deprivation index and rurality in relation to financial toxicity among breast cancer surgical patients - Investigating geospatial differences in risk profiles Cancer Research 2022, 82: p4-10-13-p4-10-13. DOI: 10.1158/1538-7445.sabcs21-p4-10-13.
  • ASO Visual Abstract: Association of Medicaid Expansion on Postmastectomy Reconstruction RatesLe Blanc J, Golshan M, Lannin D, Greenup R, Berger E, Saridakis A, Horowitz N, Zanieski G, Avraham T, Mastrioanni M, Park T. ASO Visual Abstract: Association of Medicaid Expansion on Postmastectomy Reconstruction Rates Annals Of Surgical Oncology 2022, 29: 2191-2192. DOI: 10.1245/s10434-021-10944-9.
  • Racial and Ethnic Disparities in Surgical Outcomes after Postmastectomy Breast ReconstructionSarver M, Rames J, Ren Y, Greenup R, Hwang E, Hollenbeck S, Hyslop T, Butler P, Phillips B, Fayanju O. Racial and Ethnic Disparities in Surgical Outcomes after Postmastectomy Breast Reconstruction Journal Of The American College Of Surgeons 2021, 233: s29. DOI: 10.1016/j.jamcollsurg.2021.07.034.
  • ASO Visual Abstract: Dissatisfaction After Post-Mastectomy Breast Reconstruction: A Mixed-Methods StudyShammas R, Fish L, Sergesketter A, Offodile A, Phillips B, Oshima S, Lee C, Hollenbeck S, Greenup R. ASO Visual Abstract: Dissatisfaction After Post-Mastectomy Breast Reconstruction: A Mixed-Methods Study Annals Of Surgical Oncology 2021, 28: 720-721. DOI: 10.1245/s10434-021-10779-4.
  • ASO Visual Abstract: Contralateral Axillary Nodal Metastases—Stage IV Disease or a Manifestation of Progressive Locally Advanced Breast Cancer?Nash A, Thomas S, Plichta J, Fayanju O, Hwang E, Greenup R, Rosenberger L. ASO Visual Abstract: Contralateral Axillary Nodal Metastases—Stage IV Disease or a Manifestation of Progressive Locally Advanced Breast Cancer? Annals Of Surgical Oncology 2021, 28: 608-609. DOI: 10.1245/s10434-021-10605-x.
  • Assessing the use of low value oncology care following the release of Choosing Wisely guidelines.Gunn A, Sarver M, Kaplan S, Zafar Y, Greenup R. Assessing the use of low value oncology care following the release of Choosing Wisely guidelines. Journal Of Clinical Oncology 2021, 39: e18861-e18861. DOI: 10.1200/jco.2021.39.15_suppl.e18861.
  • Characterizing participants in the North Carolina Breast and Cervical Cancer Control Program (NC BCCCP): A review of 90,000 women.Tait S, Ren Y, Horton C, Oshima S, Thomas S, Wright S, Caesar A, Plichta J, Hwang E, Greenup R, Rosenberger L, DiLalla G, Menendez C, Tolnitch L, Hyslop T, Nelson D, Fayanju O. Characterizing participants in the North Carolina Breast and Cervical Cancer Control Program (NC BCCCP): A review of 90,000 women. Journal Of Clinical Oncology 2020, 38: 101-101. DOI: 10.1200/jco.2020.38.29_suppl.101.
  • The effect of body mass index (BMI) on survival in patients with breast cancer and obesity-associated conditions.Caddell K, Ren Y, Sampathkumar A, Almond C, Ladipo O, Champ C, Rosenberger L, Greenup R, Plichta J, DiLalla G, Menendez C, Tolnitch L, Hwang E, Hyslop T, Fayanju O. The effect of body mass index (BMI) on survival in patients with breast cancer and obesity-associated conditions. Journal Of Clinical Oncology 2020, 38: 203-203. DOI: 10.1200/jco.2020.38.29_suppl.203.
  • Contralateral Prophylactic Mastectomy and Financial Toxicity: A Single-Institution Propensity-Matched AnalysisAsaad M, Boukovalas S, Chu C, Lin Y, Checka C, Greenup R, Offodile A. Contralateral Prophylactic Mastectomy and Financial Toxicity: A Single-Institution Propensity-Matched Analysis Journal Of The American College Of Surgeons 2020, 231: e82. DOI: 10.1016/j.jamcollsurg.2020.08.205.
  • Missing data in breast cancer: Relationship with survival in national databases.Plichta J, Rushing C, Lewis H, Blazer D, Hyslop T, Greenup R. Missing data in breast cancer: Relationship with survival in national databases. Journal Of Clinical Oncology 2020, 38: e19114-e19114. DOI: 10.1200/jco.2020.38.15_suppl.e19114.
  • Abstract P3-08-10: Characterization of oncotype DX recurrence score and chemotherapy utilization patterns in young women (≤40) with early stage ER+/HER-, lymph node negative breast cancerSammons S, Ren Y, Force J, Fayanju O, Rosenberger L, Plichta J, Kimmick G, Westbrook K, Dent S, Anders C, Thomas S, Hyslop T, Hwang E, Marcom P, Greenup R. Abstract P3-08-10: Characterization of oncotype DX recurrence score and chemotherapy utilization patterns in young women (≤40) with early stage ER+/HER-, lymph node negative breast cancer Cancer Research 2020, 80: p3-08-10-p3-08-10. DOI: 10.1158/1538-7445.sabcs19-p3-08-10.
  • Breast SurgeryGreenup R, Rosenberger L. Breast Surgery 2020, 183-188. DOI: 10.1007/978-3-030-29271-3_20.
  • Cost of Reconstruction: A Qualitative Study of Women after Breast CancerLane W, Rushing C, Mundy L, Shammas R, Hollenbeck S, Fish L, Greenup R. Cost of Reconstruction: A Qualitative Study of Women after Breast Cancer Journal Of The American College Of Surgeons 2019, 229: s147. DOI: 10.1016/j.jamcollsurg.2019.08.325.
  • Ductal carcinoma in situ in the elderly: what is the ideal treatment plan?DeChant C, Thomas S, Rosenberger L, Fayanju O, Greenup R, Hwang E, Plichta J. Ductal carcinoma in situ in the elderly: what is the ideal treatment plan? Journal Of Unexplored Medical Data 2019, 2019 DOI: 10.20517/2572-8180.2019.07.
  • Abstract GS2-03: Pathological complete response after neoadjuvant chemotherapy and impact on breast cancer recurrence and mortality, stratified by breast cancer subtypes and adjuvant chemotherapy usage: Individual patient-level meta-analyses of over 27,000 patientsSpring L, Fell G, Arfe A, Trippa L, Greenup R, Reynolds K, Smith B, Moy B, Isakoff S, Parmigiani G, Bardia A. Abstract GS2-03: Pathological complete response after neoadjuvant chemotherapy and impact on breast cancer recurrence and mortality, stratified by breast cancer subtypes and adjuvant chemotherapy usage: Individual patient-level meta-analyses of over 27,000 patients Cancer Research 2019, 79: gs2-03-gs2-03. DOI: 10.1158/1538-7445.sabcs18-gs2-03.
  • Abstract PD6-08: Medicare costs for women after breast cancer: Preparing for survivorshipGreenup R, Yashkin A, Gorbunova G, Akusevich I, Hwang E. Abstract PD6-08: Medicare costs for women after breast cancer: Preparing for survivorship Cancer Research 2019, 79: pd6-08-pd6-08. DOI: 10.1158/1538-7445.sabcs18-pd6-08.
  • The quality of breast cancer quality measures.Lane W, Rushing C, Nussbaum D, Blazer D, Greenup R. The quality of breast cancer quality measures. Journal Of Clinical Oncology 2018, 36: 108-108. DOI: 10.1200/jco.2018.36.30_suppl.108.
  • The costs of breast cancer care: Patient-reported experiences and preferences for transparency.Greenup R, Rushing C, Fish L, Hyslop T, Peppercorn J, Wheeler S, Zafar Y, Myers E, Hwang E. The costs of breast cancer care: Patient-reported experiences and preferences for transparency. Journal Of Clinical Oncology 2018, 36: 207-207. DOI: 10.1200/jco.2018.36.30_suppl.207.
  • Evolving Patterns of Postmastectomy Breast Reconstruction by Race/Ethnicity: A Surveillance, Epidemiology, and End Results Analysis from 1998 to 2014Sergesketter A, Thomas S, Lane W, Orr J, Fayanju O, Greenup R, Hollenbeck S. Evolving Patterns of Postmastectomy Breast Reconstruction by Race/Ethnicity: A Surveillance, Epidemiology, and End Results Analysis from 1998 to 2014 Journal Of The American College Of Surgeons 2018, 227: s207. DOI: 10.1016/j.jamcollsurg.2018.07.453.
  • The impact of chemotherapy sequence on survival in node-positive invasive lobular carcinoma.Tamirisa N, Vernia H, Thomas S, Westbrook K, Greenup R, Plichta J, Rosenberger L, Hyslop T, Hwang E, Fayanju O. The impact of chemotherapy sequence on survival in node-positive invasive lobular carcinoma. Journal Of Clinical Oncology 2018, 36: 587-587. DOI: 10.1200/jco.2018.36.15_suppl.587.
  • Restaging de novo metastatic breast cancer to refine prognostic estimates.Plichta J, Thomas S, Sergesketter A, Fayanju O, Greenup R, Rosenberger L, Kimmick G, Hyslop T, Hwang E. Restaging de novo metastatic breast cancer to refine prognostic estimates. Journal Of Clinical Oncology 2018, 36: e13083-e13083. DOI: 10.1200/jco.2018.36.15_suppl.e13083.
  • Abstract P6-10-01: Incidence and mortality among breast cancer patients < 40 years old: U.S. trends from 1992-2014Oyekunle T, Thomas S, Greenup R, Hyslop T, Blackwell K. Abstract P6-10-01: Incidence and mortality among breast cancer patients < 40 years old: U.S. trends from 1992-2014 Cancer Research 2018, 78: p6-10-01-p6-10-01. DOI: 10.1158/1538-7445.sabcs17-p6-10-01.
  • Quality in Cancer Care: An Assessment of the American College of Surgeons Commission on Cancer Quality MeasuresNussbaum D, Blazer D, Greenup R, Sun Z, Yerokun B, Rushing C, Niedzwiecki D. Quality in Cancer Care: An Assessment of the American College of Surgeons Commission on Cancer Quality Measures Journal Of The American College Of Surgeons 2017, 225: s125. DOI: 10.1016/j.jamcollsurg.2017.07.275.
  • Role of axillary node dissection after mastectomy with positive sentinel nodes.Park T, Thomas S, Greenup R, Hwang E. Role of axillary node dissection after mastectomy with positive sentinel nodes. Journal Of Clinical Oncology 2017, 35: 554-554. DOI: 10.1200/jco.2017.35.15_suppl.554.
  • Temporal associations between prognostic indicators and overall survival after breast cancer.Plichta J, Thomas S, Fayanju O, Rosenberger L, Park T, Hyslop T, Greenup R, Hwang E. Temporal associations between prognostic indicators and overall survival after breast cancer. Journal Of Clinical Oncology 2017, 35: e18144-e18144. DOI: 10.1200/jco.2017.35.15_suppl.e18144.
  • The epidemiology of metaplastic breast cancer: A review of 2,500 cases from the national cancer database.Campbell B, Thomas S, Ong C, Greenup R, Plichta J, Rosenberger L, Force J, Hyslop T, Hwang E, Fayanju O. The epidemiology of metaplastic breast cancer: A review of 2,500 cases from the national cancer database. Journal Of Clinical Oncology 2017, 35: 1570-1570. DOI: 10.1200/jco.2017.35.15_suppl.1570.
  • A population-based analysis of treatment and outcomes in 2,500 metaplastic breast cancer patients.Ong C, Thomas S, Campbell B, Greenup R, Plichta J, Rosenberger L, Force J, Hyslop T, Hwang E, Fayanju O. A population-based analysis of treatment and outcomes in 2,500 metaplastic breast cancer patients. Journal Of Clinical Oncology 2017, 35: 532-532. DOI: 10.1200/jco.2017.35.15_suppl.532.
  • Impact of insurance status on treatment for stage 0-IV breast cancer.Greenup R, Thomas S, Fayanju O, Hyslop T, Hwang E. Impact of insurance status on treatment for stage 0-IV breast cancer. Journal Of Clinical Oncology 2017, 35: 6532-6532. DOI: 10.1200/jco.2017.35.15_suppl.6532.
  • Self-Reported Factors Associated with Surgeon Comfort with Performing Contralateral Prophylactic MastectomyBellavance E, Yao K, Greenup R, Keune J, Lynch J, Colyar D, Tilburt J, Hlubocky F, Peppercorn J. Self-Reported Factors Associated with Surgeon Comfort with Performing Contralateral Prophylactic Mastectomy Journal Of The American College Of Surgeons 2016, 223: e16-e17. DOI: 10.1016/j.jamcollsurg.2016.08.046.
  • The Promise and Perils of Shared Decision-Making in Clinical PracticeGreenup R, Peppercorn J. The Promise and Perils of Shared Decision-Making in Clinical Practice 2016, 293-305. DOI: 10.1007/978-1-4939-3486-7_21.
  • Abstract 1439: Pathological complete response after neoadjuvant chemotherapy predicts improved survival in all major subtypes of breast cancer: systematic review and meta-analyses of over 18,000 patientsSpring L, Greenup R, Reynolds K, Smith B, Moy B, Bardia A. Abstract 1439: Pathological complete response after neoadjuvant chemotherapy predicts improved survival in all major subtypes of breast cancer: systematic review and meta-analyses of over 18,000 patients Cancer Research 2016, 76: 1439-1439. DOI: 10.1158/1538-7445.am2016-1439.
  • Value of prophylactic mastectomy in BRCA mutation carriers with ovarian cancerGamble C, Havrilesky L, Hollenbeck S, Myers E, Greenup R. Value of prophylactic mastectomy in BRCA mutation carriers with ovarian cancer Gynecologic Oncology 2016, 141: 58-59. DOI: 10.1016/j.ygyno.2016.04.173.
  • Combining Prophylactic Oophorectomy with Mastectomy Does Not Adversely Affect Surgical Outcomes: Results from the NSQIP DatabaseBlau J, Gamble C, Anolik R, Havrilesky L, Greenup R, Hollenbeck S. Combining Prophylactic Oophorectomy with Mastectomy Does Not Adversely Affect Surgical Outcomes: Results from the NSQIP Database Journal Of The American College Of Surgeons 2015, 221: s113. DOI: 10.1016/j.jamcollsurg.2015.07.263.
  • Vascular Patterns on Preoperative Breast MRI Predict Ischemia and Necrosis after Nipple-Sparing MastectomyPien I, Bahl M, Buretta K, Greenup R, Ghate S, Hollenbeck S. Vascular Patterns on Preoperative Breast MRI Predict Ischemia and Necrosis after Nipple-Sparing Mastectomy Journal Of The American College Of Surgeons 2015, 221: s120. DOI: 10.1016/j.jamcollsurg.2015.07.282.
  • Abstract SY36-03: Intraoperative molecular imaging with protease-activated fluorescent imaging agentsWhitley M, Cardona D, Blazer D, Hwang S, Greenup R, Mosca P, Cahill J, Mito J, Cuneo K, Larrier N, O'Reilly E, Spasojevic I, Riedel R, Eward W, Griffith L, Bawendi M, Ferrer J, Strasfeld D, Lee W, Brigman B, Kirsch D. Abstract SY36-03: Intraoperative molecular imaging with protease-activated fluorescent imaging agents 2015, sy36-03-sy36-03. DOI: 10.1158/1538-7445.am2015-sy36-03.
  • Abstract P1-10-02: Adjuvant radiation after lumpectomy: A cost comparison of treatment patterns in 43,247 women from the National Cancer Data BaseGreenup R, Blitzblau R, Houck K, Horton J, Howie L, Palta M, Mackey A, Scheri R, Sosa J, Taghian A, Peppercorn J, Smith B, Hwang E. Abstract P1-10-02: Adjuvant radiation after lumpectomy: A cost comparison of treatment patterns in 43,247 women from the National Cancer Data Base 2015, p1-10-02-p1-10-02. DOI: 10.1158/1538-7445.sabcs14-p1-10-02.
  • Abstract P1-15-10: Low utilization of hypofractionated radiotherapy for the treatment of early-stage breast cancer in the USMowery Y, Greenup R, Houck K, Palta M, Horton J, Hwang E, Sosa J, Blitzblau R. Abstract P1-15-10: Low utilization of hypofractionated radiotherapy for the treatment of early-stage breast cancer in the US 2015, p1-15-10-p1-15-10. DOI: 10.1158/1538-7445.sabcs14-p1-15-10.
  • Abstract P3-07-22: Predictors of neoadjuvant chemotherapy use in women with breast cancer: A review of 169,329 patients from the American College of Surgeons' National Cancer DatabaseHowie L, Greenup R, Houck K, Sosa J, Hwang E, Peppercorn J. Abstract P3-07-22: Predictors of neoadjuvant chemotherapy use in women with breast cancer: A review of 169,329 patients from the American College of Surgeons' National Cancer Database 2015, p3-07-22-p3-07-22. DOI: 10.1158/1538-7445.sabcs14-p3-07-22.
  • Abstract P5-15-11: The distress screening tool: Initial experience with electronically curated patient reported measuresHwang S, Power S, Stashko I, Blitzblau R, Greenup R, Horton J, Westbrook K, Blackwell K, Sperling H, Peppercorn J, Kimmick G, Marcom K. Abstract P5-15-11: The distress screening tool: Initial experience with electronically curated patient reported measures 2015, p5-15-11-p5-15-11. DOI: 10.1158/1538-7445.sabcs14-p5-15-11.
  • Trends in treatment patterns and outcomes for DCIS patients: A SEER population-based analysis.Worni M, Greenup R, Mackey A, Akushevich I, Hwang S. Trends in treatment patterns and outcomes for DCIS patients: A SEER population-based analysis. Journal Of Clinical Oncology 2014, 32: 1007-1007. DOI: 10.1200/jco.2014.32.15_suppl.1007.
  • Physician experience and attitudes toward addressing the cost of cancer care.Altomare I, Irwin B, Zafar Y, Houck K, Maloney B, Greenup R, Peppercorn J. Physician experience and attitudes toward addressing the cost of cancer care. Journal Of Clinical Oncology 2014, 32: 6561-6561. DOI: 10.1200/jco.2014.32.15_suppl.6561.
  • New Treatment Paradigms for Patients with Ductal Carcinoma In SituMackey A, Greenup R, Hwang E. New Treatment Paradigms for Patients with Ductal Carcinoma In Situ Current Breast Cancer Reports 2013, 5: 86-98. DOI: 10.1007/s12609-013-0109-9.
  • Association of pathologic complete response following neoadjuvant chemotherapy with survival among young women with breast cancer.Greenup R, Bardia A, Buckley J, Niemierko A, Camp M, Coopey S, Gadd M, Schapira L, Taghian A, Smith B, Specht M. Association of pathologic complete response following neoadjuvant chemotherapy with survival among young women with breast cancer. Journal Of Clinical Oncology 2012, 30: 1122-1122. DOI: 10.1200/jco.2012.30.15_suppl.1122.
  • Quality of life in cancer survivors: The surgeon's roleGreenup R, Lal A, Walsh M, Pappas S, Trentham-Dietz A. Quality of life in cancer survivors: The surgeon's role Journal Of The American College Of Surgeons 2009, 209: s106. DOI: 10.1016/j.jamcollsurg.2009.06.264.
  • QS114. Patient Perception of Physician Commitment Affects Quality of Life in Breast Cancer SurvivorsGreenup R, Lal A, Trentham-Dietz A. QS114. Patient Perception of Physician Commitment Affects Quality of Life in Breast Cancer Survivors Journal Of Surgical Research 2009, 151: 287. DOI: 10.1016/j.jss.2008.11.410.