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Nancy Carrasco, MD
Professor Adjunct
Contact Information
Nancy Carrasco, MD
Office
203.785.4117
Email
nancy.carrasco@yale.edu
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Carrasco Lab
Sterling Hall of Medicine, B-Wing
333 Cedar Street, Ste BE-60
New Haven, CT 06510
Research & Publications
Biography
News
Locations
Selected Publications
Sustained ERK inhibition maximizes responses of BrafV600E thyroid cancers to radioiodine
Nagarajah J, Le M, Knauf JA, Ferrandino G, Montero-Conde C, Pillarsetty N, Bolaender A, Irwin C, Krishnamoorthy GP, Saqcena M, Larson SM, Ho AL, Seshan V, Ishii N,
Carrasco N
, Rosen N, Weber WA, Fagin JA. Sustained ERK inhibition maximizes responses of BrafV600E thyroid cancers to radioiodine Journal Of Clinical Investigation 2016, 126: 4119-4124.
PMID: 27669459
,
PMCID: PMC5096947
,
DOI: 10.1172/jci89067
.
Na+ coordination at the Na2 site of the Na+/I− symporter
Ferrandino G, Nicola JP, Sánchez YE, Echeverria I, Liu Y, Amzel LM,
Carrasco N
. Na+ coordination at the Na2 site of the Na+/I− symporter Proceedings Of The National Academy Of Sciences Of The United States Of America 2016, 113: e5379-e5388.
PMID: 27562170
,
PMCID: PMC5027462
,
DOI: 10.1073/pnas.1607231113
.
Physiological sodium concentrations enhance the iodide affinity of the Na+/I− symporter
Nicola JP,
Carrasco N
, Mario Amzel L. Physiological sodium concentrations enhance the iodide affinity of the Na+/I− symporter Nature Communications 2014, 5: 3948.
PMID: 24888603
,
PMCID: PMC4248369
,
DOI: 10.1038/ncomms4948
.
Asn441 plays a key role in folding and function of the Na+/I– symporter (NIS)
Li W, Nicola JP, Amzel LM,
Carrasco N
. Asn441 plays a key role in folding and function of the Na+/I– symporter (NIS) The FASEB Journal 2013, 27: 3229-3238.
PMID: 23650190
,
PMCID: PMC3714583
,
DOI: 10.1096/fj.13-229138
.
The iodide-transport-defect-causing mutation R124H: a δ-amino group at position 124 is critical for maturation and trafficking of the Na+/I− symporter
Paroder V, Nicola JP, Ginter CS,
Carrasco N
. The iodide-transport-defect-causing mutation R124H: a δ-amino group at position 124 is critical for maturation and trafficking of the Na+/I− symporter Journal Of Cell Science 2013, 126: 3305-3313.
PMID: 23690546
,
PMCID: PMC3730242
,
DOI: 10.1242/jcs.120246
.
Mechanism of anion selectivity and stoichiometry of the Na+/I- symporter (NIS)
Paroder-Belenitsky M, Maestas MJ, Dohán O, Nicola JP, Reyna-Neyra A, Follenzi A, Dadachova E, Eskandari S, Amzel LM,
Carrasco N
. Mechanism of anion selectivity and stoichiometry of the Na+/I- symporter (NIS) Proceedings Of The National Academy Of Sciences Of The United States Of America 2011, 108: 17933-17938.
PMID: 22011571
,
PMCID: PMC3207644
,
DOI: 10.1073/pnas.1108278108
.
Kcne2 deletion uncovers its crucial role in thyroid hormone biosynthesis
Roepke TK, King EC, Reyna-Neyra A, Paroder M, Purtell K, Koba W, Fine E, Lerner DJ,
Carrasco N
, Abbott GW. Kcne2 deletion uncovers its crucial role in thyroid hormone biosynthesis Nature Medicine 2009, 15: 1186-1194.
PMID: 19767733
,
PMCID: PMC2790327
,
DOI: 10.1038/nm.2029
.
The Na+/I− symporter (NIS) mediates electroneutral active transport of the environmental pollutant perchlorate
Dohán O, Portulano C, Basquin C, Reyna-Neyra A, Amzel LM,
Carrasco N
. The Na+/I− symporter (NIS) mediates electroneutral active transport of the environmental pollutant perchlorate Proceedings Of The National Academy Of Sciences Of The United States Of America 2007, 104: 20250-20255.
PMID: 18077370
,
PMCID: PMC2154417
,
DOI: 10.1073/pnas.0707207104
.
Amino Acid Residues in Transmembrane Segment IX of the Na+/I– Symporter Play a Role in Its Na+ Dependence and Are Critical for Transport Activity*
De la Vieja A, Reed MD, Ginter CS,
Carrasco N
. Amino Acid Residues in Transmembrane Segment IX of the Na+/I– Symporter Play a Role in Its Na+ Dependence and Are Critical for Transport Activity* Journal Of Biological Chemistry 2007, 282: 25290-25298.
PMID: 17606623
,
DOI: 10.1074/jbc.m700147200
.
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