Mary-Anne "Annie" Hartley
MD, PhD, MPH
Assistant Professor of Biomedical Informatics and Data Science; Affiliated Faculty, Yale Institute for Global Health
Research & Publications
Biography
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Coauthors
Selected Publications
- Modular Clinical Decision Support Networks (MoDN)—Updatable, interpretable, and portable predictions for evolving clinical environmentsTrottet C, Vogels T, Keitel K, Kulinkina A, Tan R, Cobuccio L, Jaggi M, Hartley M. Modular Clinical Decision Support Networks (MoDN)—Updatable, interpretable, and portable predictions for evolving clinical environments. PLOS Digital Health 2023, 2: e0000108. PMID: 37459285, PMCID: PMC10351690, DOI: 10.1371/journal.pdig.0000108.
- Barriers and facilitators to implementation of point-of-care lung ultrasonography in a tertiary centre in Benin: a qualitative study among general physicians and pneumologistsSuttels V, Da Costa S, Garcia E, Brahier T, Hartley M, Agodokpessi G, Wachinou P, Fasseur F, Boillat-Blanco N. Barriers and facilitators to implementation of point-of-care lung ultrasonography in a tertiary centre in Benin: a qualitative study among general physicians and pneumologists. BMJ Open 2023, 13: e070765. PMID: 37369423, PMCID: PMC10357755, DOI: 10.1136/bmjopen-2022-070765.
- DeepBreath—automated detection of respiratory pathology from lung auscultation in 572 pediatric outpatients across 5 countriesHeitmann J, Glangetas A, Doenz J, Dervaux J, Shama D, Garcia D, Benissa M, Cantais A, Perez A, Müller D, Chavdarova T, Ruchonnet-Metrailler I, Siebert J, Lacroix L, Jaggi M, Gervaix A, Hartley M. DeepBreath—automated detection of respiratory pathology from lung auscultation in 572 pediatric outpatients across 5 countries. Npj Digital Medicine 2023, 6: 104. PMID: 37268730, PMCID: PMC10238513, DOI: 10.1038/s41746-023-00838-3.
- What If…? Pandemic policy-decision-support to guide a cost-benefit-optimised, country-specific responseMannarini G, Posa F, Bossy T, Massemin L, Fernandez-Castanon J, Chavdarova T, Cañas P, Gupta P, Jaggi M, Hartley M. What If…? Pandemic policy-decision-support to guide a cost-benefit-optimised, country-specific response. PLOS Global Public Health 2022, 2: e0000721. PMID: 36962770, PMCID: PMC10022143, DOI: 10.1371/journal.pgph.0000721.
- Genomic Diversity of Torque Teno Virus in Blood Samples from Febrile Paediatric Outpatients in Tanzania: A Descriptive Cohort StudyLaubscher F, Hartley M, Kaiser L, Cordey S. Genomic Diversity of Torque Teno Virus in Blood Samples from Febrile Paediatric Outpatients in Tanzania: A Descriptive Cohort Study. Viruses 2022, 14: 1612. PMID: 35893678, PMCID: PMC9330782, DOI: 10.3390/v14081612.
- Point-of-care ultrasound for tuberculosis management in Sub-Saharan Africa—a balanced SWOT analysisSuttels V, Du Toit J, Fiogbé A, Wachinou A, Guendehou B, Alovokpinhou F, Toukoui P, Hada A, Sefou F, Vinasse P, Makpemikpa G, Capo-Chichi D, Garcia E, Brahier T, Keitel K, Ouattara K, Cissoko Y, Beye S, Mans P, Agodokpessi G, Boillat-Blanco N, Hartley M. Point-of-care ultrasound for tuberculosis management in Sub-Saharan Africa—a balanced SWOT analysis. International Journal Of Infectious Diseases 2022, 123: 46-51. PMID: 35811083, DOI: 10.1016/j.ijid.2022.07.009.
- Point-of-care lung ultrasonography for early identification of mild COVID-19: a prospective cohort of outpatients in a Swiss screening centerSchaad S, Brahier T, Hartley M, Cordonnier J, Bosso L, Espejo T, Pantet O, Hugli O, Carron P, Meuwly J, Boillat-Blanco N. Point-of-care lung ultrasonography for early identification of mild COVID-19: a prospective cohort of outpatients in a Swiss screening center. BMJ Open 2022, 12: e060181. PMID: 35750462, PMCID: PMC9234434, DOI: 10.1136/bmjopen-2021-060181.
- Ultrasound for point-of-care sputum-free tuberculosis detection: Building collaborative standardized image-banksSuttels V, Wachinou P, Du Toit J, Boillat-Blanco N, Hartley M. Ultrasound for point-of-care sputum-free tuberculosis detection: Building collaborative standardized image-banks. EBioMedicine 2022, 81: 104078. PMID: 35649304, PMCID: PMC9160315, DOI: 10.1016/j.ebiom.2022.104078.
- Blood virosphere in febrile Tanzanian childrenCordey S, Laubscher F, Hartley M, Junier T, Keitel K, Docquier M, Guex N, Iseli C, Vieille G, Le Mercier P, Gleizes A, Samaka J, Mlaganile T, Kagoro F, Masimba J, Said Z, Temba H, Elbanna G, Tapparel C, Zanella M, Xenarios I, Fellay J, D’Acremont V, Kaiser L. Blood virosphere in febrile Tanzanian children. Emerging Microbes & Infections 2021, 10: 982-993. PMID: 33929935, PMCID: PMC8171259, DOI: 10.1080/22221751.2021.1925161.
- Weight Erosion: An Update Aggregation Scheme for Personalized Collaborative Machine LearningGrimberg F, Hartley M, Jaggi M, Karimireddy S. Weight Erosion: An Update Aggregation Scheme for Personalized Collaborative Machine Learning. 2020, 12444: 160-169. DOI: 10.1007/978-3-030-60548-3_16.
- Clinical relevance of low-density Plasmodium falciparum parasitemia in untreated febrile children: A cohort studyHartley M, Hofmann N, Keitel K, Kagoro F, Moniz C, Mlaganile T, Samaka J, Masimba J, Said Z, Temba H, Gonzalez I, Felger I, Genton B, D’Acremont V. Clinical relevance of low-density Plasmodium falciparum parasitemia in untreated febrile children: A cohort study. PLOS Medicine 2020, 17: e1003318. PMID: 32956354, PMCID: PMC7505590, DOI: 10.1371/journal.pmed.1003318.
- Lung Ultrasonography for Risk Stratification in Patients with Coronavirus Disease 2019 (COVID-19): A Prospective Observational Cohort StudyBrahier T, Meuwly J, Pantet O, Vez M, Donnet H, Hartley M, Hugli O, Boillat-Blanco N. Lung Ultrasonography for Risk Stratification in Patients with Coronavirus Disease 2019 (COVID-19): A Prospective Observational Cohort Study. Clinical Infectious Diseases 2020, 73: e4189-e4196. PMID: 32940646, PMCID: PMC7543331, DOI: 10.1093/cid/ciaa1408.
- Nearly Complete Genome Sequence of a Novel Phlebovirus-Like Virus Detected in a Human Plasma Sample by High-Throughput SequencingLaubscher F, Cordey S, Hartley M, Vieille G, Boillat-Blanco N, Samaka J, Mlaganile T, d’Acremont V, Kaiser L. Nearly Complete Genome Sequence of a Novel Phlebovirus-Like Virus Detected in a Human Plasma Sample by High-Throughput Sequencing. Microbiology Resource Announcements 2019, 8: e00764-19. PMID: 31467101, PMCID: PMC6715871, DOI: 10.1128/mra.00764-19.
- Machine-learning Prognostic Models from the 2014–16 Ebola Outbreak: Data-harmonization Challenges, Validation Strategies, and mHealth ApplicationsColubri A, Hartley M, Siakor M, Wolfman V, Felix A, Sesay T, Shaffer J, Garry R, Grant D, Levine A, Sabeti P. Machine-learning Prognostic Models from the 2014–16 Ebola Outbreak: Data-harmonization Challenges, Validation Strategies, and mHealth Applications. EClinicalMedicine 2019, 11: 54-64. PMID: 31312805, PMCID: PMC6610774, DOI: 10.1016/j.eclinm.2019.06.003.
- Detection of dicistroviruses RNA in blood of febrile Tanzanian childrenCordey S, Laubscher F, Hartley M, Junier T, Pérez-Rodriguez F, Keitel K, Vieille G, Samaka J, Mlaganile T, Kagoro F, Boillat-Blanco N, Mbarack Z, Docquier M, Brito F, Eibach D, May J, Sothmann P, Aldrich C, Lusingu J, Tapparel C, D’Acremont V, Kaiser L. Detection of dicistroviruses RNA in blood of febrile Tanzanian children. Emerging Microbes & Infections 2019, 8: 613-623. PMID: 30999808, PMCID: PMC6493270, DOI: 10.1080/22221751.2019.1603791.
- Leishmania guyanensis parasites block the activation of the inflammasome by inhibiting maturation of IL-1βHartley M, Eren R, Rossi M, Prevel F, Castiglioni P, Isorce N, Desponds C, Lye L, Beverley S, Drexler S, Fasel N. Leishmania guyanensis parasites block the activation of the inflammasome by inhibiting maturation of IL-1β. Microbial Cell 2018, 5: 137. PMID: 29487860, PMCID: PMC5826701, DOI: 10.15698/mic2018.03.619.
- Predicting Ebola infection: A malaria-sensitive triage score for Ebola virus diseaseHartley M, Young A, Tran A, Okoni-Williams H, Suma M, Mancuso B, Al-Dikhari A, Faouzi M. Predicting Ebola infection: A malaria-sensitive triage score for Ebola virus disease. PLOS Neglected Tropical Diseases 2017, 11: e0005356. PMID: 28231242, PMCID: PMC5322888, DOI: 10.1371/journal.pntd.0005356.
- Predicting Ebola Severity: A Clinical Prioritization Score for Ebola Virus DiseaseHartley M, Young A, Tran A, Okoni-Williams H, Suma M, Mancuso B, Al-Dikhari A, Faouzi M. Predicting Ebola Severity: A Clinical Prioritization Score for Ebola Virus Disease. PLOS Neglected Tropical Diseases 2017, 11: e0005265. PMID: 28151955, PMCID: PMC5289426, DOI: 10.1371/journal.pntd.0005265.
- Exacerbated Leishmaniasis Caused by a Viral Endosymbiont can be Prevented by Immunization with Its Viral CapsidCastiglioni P, Hartley M, Rossi M, Prevel F, Desponds C, Utzschneider D, Eren R, Zangger H, Brunner L, Collin N, Zehn D, Kuhlmann F, Beverley S, Fasel N, Ronet C. Exacerbated Leishmaniasis Caused by a Viral Endosymbiont can be Prevented by Immunization with Its Viral Capsid. PLOS Neglected Tropical Diseases 2017, 11: e0005240. PMID: 28099431, PMCID: PMC5242429, DOI: 10.1371/journal.pntd.0005240.
- Leishmaniavirus-Dependent Metastatic Leishmaniasis Is Prevented by Blocking IL-17AHartley M, Bourreau E, Rossi M, Castiglioni P, Eren R, Prevel F, Couppié P, Hickerson S, Launois P, Beverley S, Ronet C, Fasel N. Leishmaniavirus-Dependent Metastatic Leishmaniasis Is Prevented by Blocking IL-17A. PLOS Pathogens 2016, 12: e1005852. PMID: 27658195, PMCID: PMC5033371, DOI: 10.1371/journal.ppat.1005852.
- Mammalian Innate Immune Response to a Leishmania-Resident RNA Virus Increases Macrophage Survival to Promote Parasite PersistenceEren R, Reverte M, Rossi M, Hartley M, Castiglioni P, Prevel F, Martin R, Desponds C, Lye L, Drexler S, Reith W, Beverley S, Ronet C, Fasel N. Mammalian Innate Immune Response to a Leishmania-Resident RNA Virus Increases Macrophage Survival to Promote Parasite Persistence. Cell Host & Microbe 2016, 20: 318-328. PMID: 27593513, PMCID: PMC5493041, DOI: 10.1016/j.chom.2016.08.001.
- Use of Peripheral Health Units in Low-Transmission Ebola Virus Disease SurveillanceYoung A, Connolly A, Hoar A, Mancuso B, Esplana J, Kaur G, Fisher L, Hartley M, Tran A. Use of Peripheral Health Units in Low-Transmission Ebola Virus Disease Surveillance. Online Journal Of Public Health Informatics 2016, 8: e177. PMCID: PMC4854600, DOI: 10.5210/ojphi.v8i1.6596.
- Surveillance Strategies During Low Ebola Transmission in a District in Sierra LeoneConnolly A, Young A, Mancuso B, Hartley M, Hoar A, Kaur G, Esplana J, Fisher L, Tran A. Surveillance Strategies During Low Ebola Transmission in a District in Sierra Leone. Online Journal Of Public Health Informatics 2016, 8 DOI: 10.5210/ojphi.v8i1.6470.
- Strengthening Community Surveillance of Ebola Virus Disease in Sierra LeoneTran A, Hoar A, Young A, Connolly A, Hartley M, Boland S, Mancuso B, Kaur G, Esplana J, Polich E, Fisher L. Strengthening Community Surveillance of Ebola Virus Disease in Sierra Leone. Online Journal Of Public Health Informatics 2016, 8 DOI: 10.5210/ojphi.v8i1.6583.
- Severe Cutaneous Leishmaniasis in a Human Immunodeficiency Virus Patient Coinfected with Leishmania braziliensis and Its Endosymbiotic VirusParmentier L, Cusini A, Müller N, Zangger H, Hartley M, Desponds C, Castiglioni P, Dubach P, Ronet C, Beverley S, Fasel N. Severe Cutaneous Leishmaniasis in a Human Immunodeficiency Virus Patient Coinfected with Leishmania braziliensis and Its Endosymbiotic Virus. American Journal Of Tropical Medicine And Hygiene 2016, 94: 840-843. PMID: 26834198, PMCID: PMC4824227, DOI: 10.4269/ajtmh.15-0803.
- Presence of Leishmania RNA Virus 1 in Leishmania guyanensis Increases the Risk of First-Line Treatment Failure and Symptomatic RelapseBourreau E, Ginouves M, Prévot G, Hartley M, Gangneux J, Robert-Gangneux F, Dufour J, Sainte-Marie D, Bertolotti A, Pratlong F, Martin R, Schütz F, Couppié P, Fasel N, Ronet C. Presence of Leishmania RNA Virus 1 in Leishmania guyanensis Increases the Risk of First-Line Treatment Failure and Symptomatic Relapse. The Journal Of Infectious Diseases 2015, 213: 105-111. PMID: 26123564, DOI: 10.1093/infdis/jiv355.
- The immunological, environmental, and phylogenetic perpetrators of metastatic leishmaniasisHartley M, Drexler S, Ronet C, Beverley S, Fasel N. The immunological, environmental, and phylogenetic perpetrators of metastatic leishmaniasis. Trends In Parasitology 2014, 30: 412-422. PMID: 24954794, PMCID: PMC4287268, DOI: 10.1016/j.pt.2014.05.006.
- The therapeutic potential of immune cross‐talk in leishmaniasisHartley M, Kohl K, Ronet C, Fasel N. The therapeutic potential of immune cross‐talk in leishmaniasis. Clinical Microbiology And Infection 2013, 19: 119-130. PMID: 23398405, DOI: 10.1111/1469-0691.12095.
- Detection of Leishmania RNA Virus in Leishmania ParasitesZangger H, Ronet C, Desponds C, Kuhlmann FM, Robinson J, Hartley MA, Prevel F, Castiglioni P, Pratlong F, Bastien P, Müller N, Parmentier L, Saravia NG, Beverley SM, Fasel N. Detection of Leishmania RNA Virus in Leishmania Parasites. PLOS Neglected Tropical Diseases 2013, 7: e2006. PMID: 23326619, PMCID: PMC3542153, DOI: 10.1371/journal.pntd.0002006.
- Backseat drivers: the hidden influence of microbial viruses on diseaseHartley M, Ronet C, Fasel N. Backseat drivers: the hidden influence of microbial viruses on disease. Current Opinion In Microbiology 2012, 15: 538-545. PMID: 22694933, DOI: 10.1016/j.mib.2012.05.011.
- Leishmania RNA virus: when the host pays the tollHartley M, Ronet C, Zangger H, Beverley S, Fasel N. Leishmania RNA virus: when the host pays the toll. Frontiers In Cellular And Infection Microbiology 2012, 2: 99. PMID: 22919688, PMCID: PMC3417650, DOI: 10.3389/fcimb.2012.00099.