Margarita Dominguez-Villar, PhD
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About
Education & Training
- Postdoctoral Associate
- Yale School of Medicine (2012)
- Postdoctoral Associate
- Harvard Medical School and Brigham and Women's Hospital (2010)
- PhD
- University of Cadiz (2007)
- Postdoctoral Fellow
- Karolinska Institute (2007)
Research
Overview
Medical Subject Headings (MeSH)
Autoimmune Diseases
ORCID
0000-0002-9719-0028
Research at a Glance
Publications Timeline
A big-picture view of Margarita Dominguez-Villar's research output by year.
3Publications
1Citations
Publications
2024
Cell Culture Evaluation Hints Widely Available HIV Drugs Are Primed for Success if Repurposed for HTLV-1 Prevention
Kalemera M, Maher A, Dominguez-Villar M, Maertens G. Cell Culture Evaluation Hints Widely Available HIV Drugs Are Primed for Success if Repurposed for HTLV-1 Prevention. Pharmaceuticals 2024, 17: 730. PMID: 38931397, PMCID: PMC11206710, DOI: 10.3390/ph17060730.Peer-Reviewed Original ResearchAltmetricConceptsAdult T-cell leukaemia/lymphomaIntegrase strand transfer inhibitorsNucleoside reverse transcriptase inhibitorsHTLV-1Reservoir of latently infected CD4+ T cellsDevelopment of adult T-cell leukaemia/lymphomaHIV-1Latently infected CD4+ T cellsHuman T-cell lymphotropic virus type 1Infected CD4+ T cellsCD4+ T cellsHTLV-1 endemic areasAssociated with poor prognosisHTLV-1-associated pathologiesAntiretroviral therapy prescriptionT-cell leukaemia/lymphomaStrand transfer inhibitorsHTLV-1 infectionHTLV-1 transmissionReverse transcriptase inhibitorsShorter overall survivalVirus type 1HIV pillsOverall survivalHIV therapyHTLV-1 induces an inflammatory CD4+CD8+ T cell population in HTLV-1–associated myelopathy
Maher A, Aristodemou A, Giang N, Tanaka Y, Bangham C, Taylor G, Dominguez-Villar M. HTLV-1 induces an inflammatory CD4+CD8+ T cell population in HTLV-1–associated myelopathy. JCI Insight 2024, 9: e173738. PMID: 38193535, PMCID: PMC10906466, DOI: 10.1172/jci.insight.173738.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsHTLV-1-associated myelopathyDP T cellsT cellsHTLV-1Double-positive T cellsAdult T-cell leukemiaT cell populationsT-cell tropismHTLV-1 infectionHuman T-cell leukemia virus type 1Virus type 1T-cell leukemiaCXCR3 expressionPreferential CD4Asymptomatic infectionCNS pathologyIL-6Asymptomatic carriersInflammatory diseasesCytotoxic phenotypeCell leukemiaCell tropismType 1CD4Cell populations
2014
Pathogenic Antigen-Specific Th17 Cells Drive Autoimmunity Myasthenia Gravis (P1.059)
Cao Y, Dominguez-Villar M, Amezquita R, Liu S, Kleinstein S, Goldstein J, Nowak R, O'Connor K. Pathogenic Antigen-Specific Th17 Cells Drive Autoimmunity Myasthenia Gravis (P1.059). Neurology 2014, 82 DOI: 10.1212/wnl.82.10_supplement.p1.059.Peer-Reviewed Original Research
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