Tools of molecular genetics focused on the insect vector provide clues to genomic organization, population structure and evolutionary relationships. Dr. Munstermann’s research emphasizes three genetic approaches: (1) Gene linkage mapping provides genetic backbone for isolating genes and macrogenomic evolution; (2) Genetic variability within an insect species in the form of isoenzymes or DNA base pair substitutions indicate population structure, population origin or taxonomic relatedness; and (3) Identification of closely related vector species by (biochemical) genetic means. Research organisms are Aedes mosquitoes and phlebotomine sand flies of New and Old World.
A long term research focus is the geographic distribution of the insect vectors and the association with disease transmission. Species distribution maps, correlation to environmental factors and location of disease cases form a data matrix analyzable in a Geographical Information System. To better predict risk of disease outbreak-knowledge of vector species involved, vector distribution, and vector competence is required. These have been applied in the Mosquitoes of Sardinia Project and the Biogeography of New World Sand Flies.
Specialized Terms: Molecular genetics; Insect vectors; Phlebotomine sand flies; Entomology; Phylogeny; Taxonomy; Speciation
Colombia; DDT; El Salvador; Entomology; Biological Evolution; Genetics; Guatemala; Honduras; Insect Vectors; Leishmaniasis; Leishmaniasis, Visceral; Malaria; West Nile virus; Global Health; Yellow Fever; Leishmaniasis, Cutaneous; Communicable Diseases, Emerging
Emerging Infectious Diseases; Evolution; Genetics, Genomics, Epigenetics; GIS/Disease Mapping; Global Health; Infectious Diseases; Malaria; Mosquito-borne Diseases; Toxicology; Vector-borne Diseases; Tick-borne Diseases