Kazimierz Tycowski, PhD
Research Scientist in Molecular Biophysics and Biochemistry
Research & Publications
Biography
Coauthors
Selected Publications
- The vault RNA of Trypanosoma brucei plays a role in the production of trans-spliced mRNAKolev NG, Rajan KS, Tycowski KT, Toh JY, Shi H, Lei Y, Michaeli S, Tschudi C. The vault RNA of Trypanosoma brucei plays a role in the production of trans-spliced mRNA. Journal Of Biological Chemistry 2019, 294: 15559-15574. PMID: 31439669, PMCID: PMC6816085, DOI: 10.1074/jbc.ra119.008580.
- Abstract IA14: Noncoding RNAs of viral and cellular origin: Links to oncogenesisSteitz J, Lee N, Moss W, Yario T, Vilborg A, Passarelli M, Tycowski K. Abstract IA14: Noncoding RNAs of viral and cellular origin: Links to oncogenesis. Cancer Research 2016, 76: ia14-ia14. DOI: 10.1158/1538-7445.nonrna15-ia14.
- Formation of triple-helical structures by the 3′-end sequences of MALAT1 and MENβ noncoding RNAsBrown JA, Valenstein ML, Yario TA, Tycowski KT, Steitz JA. Formation of triple-helical structures by the 3′-end sequences of MALAT1 and MENβ noncoding RNAs. Proceedings Of The National Academy Of Sciences Of The United States Of America 2012, 109: 19202-19207. PMID: 23129630, PMCID: PMC3511071, DOI: 10.1073/pnas.1217338109.
- Non-coding snoRNA host genes in Drosophila: expression strategies for modification guide snoRNAsTycowski K, Steitz J. Non-coding snoRNA host genes in Drosophila: expression strategies for modification guide snoRNAs. European Journal Of Cell Biology 2001, 80: 119-125. PMID: 11302516, DOI: 10.1078/0171-9335-00150.
- Modification of U6 Spliceosomal RNA Is Guided by Other Small RNAsTycowski K, You Z, Graham P, Steitz J. Modification of U6 Spliceosomal RNA Is Guided by Other Small RNAs. Molecular Cell 1998, 2: 629-638. PMID: 9844635, DOI: 10.1016/s1097-2765(00)80161-6.
- A small nucleolar RNA requirement for site-specific ribose methylation of rRNA in XenopusTycowski K, Smith C, Shu M, Steitz J. A small nucleolar RNA requirement for site-specific ribose methylation of rRNA in Xenopus. Proceedings Of The National Academy Of Sciences Of The United States Of America 1996, 93: 14480-14485. PMID: 8962077, PMCID: PMC26158, DOI: 10.1073/pnas.93.25.14480.
- A mammalian gene with introns instead of exons generating stable RNA productsTycowski K, Shu M, Steitz J. A mammalian gene with introns instead of exons generating stable RNA products. Nature 1996, 379: 464-466. PMID: 8559254, DOI: 10.1038/379464a0.
- ENHANCED PERSPECTIVE: Small RNA Chaperones for Ribosome BiogenesisSteitz J, Tycowski K. ENHANCED PERSPECTIVE: Small RNA Chaperones for Ribosome Biogenesis. Science 1995, 270: 1626-1626. PMID: 7502072, DOI: 10.1126/science.270.5242.1626.
- Mapping of ribosomal protein S3 and internally nested snoRNA U15A gene to human chromosome 11q13.3–q13.5Polakiewicz R, Munroe D, Sait S, Tycowski K, Nowak N, Shows T, Housman D, Page D. Mapping of ribosomal protein S3 and internally nested snoRNA U15A gene to human chromosome 11q13.3–q13.5. Genomics 1995, 25: 577-580. PMID: 7789996, DOI: 10.1016/0888-7543(95)80063-r.
- Requirement for Intron-Encoded U22 Small Nucleolar RNA in 18S Ribosomal RNA MaturationTycowski K, Shu M, Steitz J. Requirement for Intron-Encoded U22 Small Nucleolar RNA in 18S Ribosomal RNA Maturation. Science 1994, 266: 1558-1561. PMID: 7985025, DOI: 10.1126/science.7985025.
- Organization of small nucleolar ribonucleoproteins (snoRNPs) by fluorescence in situ hybridization and immunocytochemistry.Matera AG, Tycowski KT, Steitz JA, Ward DC. Organization of small nucleolar ribonucleoproteins (snoRNPs) by fluorescence in situ hybridization and immunocytochemistry. Molecular Biology Of The Cell 1994, 5: 1289-1299. PMID: 7535131, PMCID: PMC301158, DOI: 10.1091/mbc.5.12.1289.
- tRNA splicing in yeast and wheat germ. A cyclic phosphodiesterase implicated in the metabolism of ADP-ribose 1“,2”-cyclic phosphate.Culver G, Consaul S, Tycowski K, Filipowicz W, Phizicky E. tRNA splicing in yeast and wheat germ. A cyclic phosphodiesterase implicated in the metabolism of ADP-ribose 1“,2”-cyclic phosphate. Journal Of Biological Chemistry 1994, 269: 24928-24934. PMID: 7929175, DOI: 10.1016/s0021-9258(17)31479-5.
- A small nucleolar RNA is processed from an intron of the human gene encoding ribosomal protein S3.Tycowski KT, Shu MD, Steitz JA. A small nucleolar RNA is processed from an intron of the human gene encoding ribosomal protein S3. Genes & Development 1993, 7: 1176-1190. PMID: 8319909, DOI: 10.1101/gad.7.7a.1176.