Krishna C. Mudumbi, PhD
Associate Research Scientist in Pharmacology
Research & Publications
Biography
Coauthors
Selected Publications
- Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranesMudumbi K, Burns E, Schodt D, Petrova Z, Kiyatkin A, Kim L, Mangiacapre E, Ortiz-Caraveo I, Rivera Ortiz H, Hu C, Ashtekar K, Lidke K, Lidke D, Lemmon M. Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranes. Cell Reports 2023, 43: 113603. PMID: 38117650, PMCID: PMC10835193, DOI: 10.1016/j.celrep.2023.113603.
- Structural basis for ligand reception by anaplastic lymphoma kinaseLi T, Stayrook SE, Tsutsui Y, Zhang J, Wang Y, Li H, Proffitt A, Krimmer SG, Ahmed M, Belliveau O, Walker IX, Mudumbi KC, Suzuki Y, Lax I, Alvarado D, Lemmon MA, Schlessinger J, Klein DE. Structural basis for ligand reception by anaplastic lymphoma kinase. Nature 2021, 600: 148-152. PMID: 34819665, PMCID: PMC8639777, DOI: 10.1038/s41586-021-04141-7.
- Nucleoplasmic signals promote directed transmembrane protein import simultaneously via multiple channels of nuclear poresMudumbi KC, Czapiewski R, Ruba A, Junod SL, Li Y, Luo W, Ngo C, Ospina V, Schirmer EC, Yang W. Nucleoplasmic signals promote directed transmembrane protein import simultaneously via multiple channels of nuclear pores. Nature Communications 2020, 11: 2184. PMID: 32366843, PMCID: PMC7198523, DOI: 10.1038/s41467-020-16033-x.
- Casting a Wider Net: Differentiating between Inner Nuclear Envelope and Outer Nuclear Envelope Transmembrane ProteinsTingey M, Mudumbi KC, Schirmer EC, Yang W. Casting a Wider Net: Differentiating between Inner Nuclear Envelope and Outer Nuclear Envelope Transmembrane Proteins. International Journal Of Molecular Sciences 2019, 20: 5248. PMID: 31652739, PMCID: PMC6862087, DOI: 10.3390/ijms20215248.
- Determination of Membrane Protein Distribution on the Nuclear Envelope by Single‐Point Single‐Molecule FRAPMudumbi K, Yang W. Determination of Membrane Protein Distribution on the Nuclear Envelope by Single‐Point Single‐Molecule FRAP. Current Protocols In Cell Biology 2017, 76: 21.11.1-21.11.13. PMID: 28862339, PMCID: PMC5879780, DOI: 10.1002/cpcb.27.
- Single-point single-molecule FRAP distinguishes inner and outer nuclear membrane protein distributionMudumbi K, Schirmer E, Yang W. Single-point single-molecule FRAP distinguishes inner and outer nuclear membrane protein distribution. Nature Communications 2016, 7: 12562. PMID: 27558844, PMCID: PMC5007294, DOI: 10.1038/ncomms12562.
- Probing Protein Distribution Along the Nuclear Envelope In Vivo by Using Single-Point FRAPMudumbi K, Yang W. Probing Protein Distribution Along the Nuclear Envelope In Vivo by Using Single-Point FRAP. 2016, 1411: 113-122. PMID: 27147037, PMCID: PMC10099394, DOI: 10.1007/978-1-4939-3530-7_6.
- The Pathogenic A391E Mutation in FGFR3 Induces a Structural Change in the Transmembrane Domain DimerMudumbi K, Julius A, Herrmann J, Li E. The Pathogenic A391E Mutation in FGFR3 Induces a Structural Change in the Transmembrane Domain Dimer. The Journal Of Membrane Biology 2013, 246: 487-493. PMID: 23727984, DOI: 10.1007/s00232-013-9563-6.