Jiang Yu
Postdoctoral Associate
Research & Publications
Biography
Coauthors
Selected Publications
- Saponins from Allii Macrostemonis Bulbus attenuate atherosclerosis by inhibiting macrophage foam cell formation and inflammationZhao S, Guo H, Qiu L, Zhong C, Xue J, Qin M, Zhang Y, Xu C, Xie Y, Yu J. Saponins from Allii Macrostemonis Bulbus attenuate atherosclerosis by inhibiting macrophage foam cell formation and inflammation. Scientific Reports 2024, 14: 12917. PMID: 38839811, PMCID: PMC11153636, DOI: 10.1038/s41598-024-61209-w.
- Anemoside B4 attenuates abdominal aortic aneurysm by limiting smooth muscle cell transdifferentiation and its mediated inflammationChu S, Shan D, He L, Yang S, Feng Y, Zhang Y, Yu J. Anemoside B4 attenuates abdominal aortic aneurysm by limiting smooth muscle cell transdifferentiation and its mediated inflammation. Frontiers In Immunology 2024, 15: 1412022. PMID: 38881898, PMCID: PMC11176519, DOI: 10.3389/fimmu.2024.1412022.
- Endothelial Mitochondria-Associated Membranes (MAMs) Isolation by Percoll Step GradientsBaldini M, Zhang C, Yu J. Endothelial Mitochondria-Associated Membranes (MAMs) Isolation by Percoll Step Gradients. 2024, 2782: 113-122. PMID: 38622396, DOI: 10.1007/978-1-0716-3754-8_8.
- Saponins from Allium macrostemon Bulbs Attenuate Endothelial Inflammation and Acute Lung Injury via the NF-κB/VCAM-1 PathwayLiu L, Qiu L, Xue J, Zhong C, Qin M, Zhang Y, Xu C, Xie Y, Yu J. Saponins from Allium macrostemon Bulbs Attenuate Endothelial Inflammation and Acute Lung Injury via the NF-κB/VCAM-1 Pathway. Molecules 2024, 29: 1239. PMID: 38542876, PMCID: PMC10976117, DOI: 10.3390/molecules29061239.
- Edgeworthia gardneri (Wall.) Meisn. Ethanolic Extract Attenuates Endothelial Activation and Alleviates Cardiac Ischemia-Reperfusion InjuryLang X, Zhong C, Su L, Qin M, Xie Y, Shan D, Cui Y, Shi M, Li M, Quan H, Qiu L, Zhong G, Yu J. Edgeworthia gardneri (Wall.) Meisn. Ethanolic Extract Attenuates Endothelial Activation and Alleviates Cardiac Ischemia-Reperfusion Injury. Molecules 2024, 29: 1068. PMID: 38474581, PMCID: PMC10935089, DOI: 10.3390/molecules29051068.
- Tiliroside Attenuates NLRP3 Inflammasome Activation in Macrophages and Protects against Acute Lung Injury in MiceZhong C, Yang J, Deng K, Lang X, Zhang J, Li M, Qiu L, Zhong G, Yu J. Tiliroside Attenuates NLRP3 Inflammasome Activation in Macrophages and Protects against Acute Lung Injury in Mice. Molecules 2023, 28: 7527. PMID: 38005247, PMCID: PMC10673355, DOI: 10.3390/molecules28227527.
- Tiliroside Protects against Lipopolysaccharide-Induced Acute Kidney Injury via Intrarenal Renin–Angiotensin System in MiceYi X, Xu C, Yang J, Zhong C, Yang H, Tang L, Song S, Yu J. Tiliroside Protects against Lipopolysaccharide-Induced Acute Kidney Injury via Intrarenal Renin–Angiotensin System in Mice. International Journal Of Molecular Sciences 2023, 24: 15556. PMID: 37958538, PMCID: PMC10648967, DOI: 10.3390/ijms242115556.
- Differential regulation of autophagy on urine-concentrating capability through modulating the renal AQP2 expression and renin-angiotensin system in miceXu C, Yi X, Tang L, Wang H, Chu S, Yu J. Differential regulation of autophagy on urine-concentrating capability through modulating the renal AQP2 expression and renin-angiotensin system in mice. American Journal Of Physiology. Renal Physiology 2023, 325: f503-f518. PMID: 37589054, DOI: 10.1152/ajprenal.00018.2023.
- Effects of maternal hypothyroidism on postnatal cardiomyocyte proliferation and cardiac disease responses of the progenyLi Y, Johnson J, Yang Y, Yu D, Kubo H, Berretta R, Wang T, Zhang X, Foster M, Yu J, Tilley D, Houser S, Chen X. Effects of maternal hypothyroidism on postnatal cardiomyocyte proliferation and cardiac disease responses of the progeny. AJP Heart And Circulatory Physiology 2023, 325: h702-h719. PMID: 37539452, PMCID: PMC10659327, DOI: 10.1152/ajpheart.00320.2023.
- Pulsatilla Saponins Inhibit Experimental Lung Metastasis of Melanoma via Targeting STAT6-Mediated M2 Macrophages PolarizationYang X, Wu M, Yan X, Zhang C, Luo Y, Yu J. Pulsatilla Saponins Inhibit Experimental Lung Metastasis of Melanoma via Targeting STAT6-Mediated M2 Macrophages Polarization. Molecules 2023, 28: 3682. PMID: 37175092, PMCID: PMC10179893, DOI: 10.3390/molecules28093682.
- Combining three independent pathological stressors induces a heart failure with preserved ejection fraction phenotypeLi Y, Kubo H, Yu D, Yang Y, Johnson J, Eaton D, Berretta R, Foster M, McKinsey T, Yu J, Elrod J, Chen X, Houser S. Combining three independent pathological stressors induces a heart failure with preserved ejection fraction phenotype. AJP Heart And Circulatory Physiology 2023, 324: h443-h460. PMID: 36763506, PMCID: PMC9988529, DOI: 10.1152/ajpheart.00594.2022.
- PGE2 stimulates aldosterone release via cAMP/sPRR/β-catenin pathway in mouse inner medullary collecting duct cellsXu C, Yi X, Qin M, Chu S, Liu C, Xiong J, Ouyang X, Yu J. PGE2 stimulates aldosterone release via cAMP/sPRR/β-catenin pathway in mouse inner medullary collecting duct cells. The Journal Of Steroid Biochemistry And Molecular Biology 2023, 225: 106205. DOI: 10.1016/j.jsbmb.2022.106205.
- Deletion of LDLRAP1 Induces Atherosclerotic Plaque Formation, Insulin Resistance, and Dysregulated Insulin Response in Adipose TissueLeigh T, Kawai T, Kelemen S, Okune R, Preston K, St. Paul A, Corbett C, Yu J, Scalia R, Autieri M. Deletion of LDLRAP1 Induces Atherosclerotic Plaque Formation, Insulin Resistance, and Dysregulated Insulin Response in Adipose Tissue. The FASEB Journal 2022, 36 DOI: 10.1096/fasebj.2022.36.s1.r5079.
- Deletion of LDLRAP1 Induces Atherosclerotic Plaque Formation, Insulin Resistance, and Dysregulated Insulin Response in Adipose TissueLeigh T, Kawai T, Preston K, Kelemen S, Okune R, St Paul A, Corbett C, Peluzzo A, Yu J, Scalia R, Autieri M. Deletion of LDLRAP1 Induces Atherosclerotic Plaque Formation, Insulin Resistance, and Dysregulated Insulin Response in Adipose Tissue. American Journal Of Pathology 2022, 192: 1092-1108. PMID: 35460615, PMCID: PMC9253916, DOI: 10.1016/j.ajpath.2022.03.014.
- Abstract 13123: Global Knockout of LDLRAP1 Regulates Atherosclerosis, Adipose Metabolism, and Insulin ResistanceLeigh T, Kawai T, Kelemen S, Okune R, Corbett C, St Paul A, Yu J, Scalia R, Autieri M. Abstract 13123: Global Knockout of LDLRAP1 Regulates Atherosclerosis, Adipose Metabolism, and Insulin Resistance. Circulation 2021, 144: a13123-a13123. DOI: 10.1161/circ.144.suppl_1.13123.
- Interleukin 35 Delays Hindlimb Ischemia-Induced Angiogenesis Through Regulating ROS-Extracellular Matrix but Spares Later Regenerative AngiogenesisFu H, Sun Y, Shao Y, Saredy J, Cueto R, Liu L, Drummer C, Johnson C, Xu K, Lu Y, Li X, Meng S, Xue E, Tan J, Jhala N, Yu D, Zhou Y, Bayless K, Yu J, Rogers T, Hu W, Snyder N, Sun J, Qin X, Jiang X, Wang H, Yang X. Interleukin 35 Delays Hindlimb Ischemia-Induced Angiogenesis Through Regulating ROS-Extracellular Matrix but Spares Later Regenerative Angiogenesis. Frontiers In Immunology 2020, 11: 595813. PMID: 33154757, PMCID: PMC7591706, DOI: 10.3389/fimmu.2020.595813.
- An allosteric site on MKP5 reveals a strategy for small-molecule inhibitionGannam Z, Min K, Shillingford SR, Zhang L, Herrington J, Abriola L, Gareiss PC, Pantouris G, Tzouvelekis A, Kaminski N, Zhang X, Yu J, Jamali H, Ellman JA, Lolis E, Anderson KS, Bennett AM. An allosteric site on MKP5 reveals a strategy for small-molecule inhibition. Science Signaling 2020, 13 PMID: 32843541, PMCID: PMC7569488, DOI: 10.1126/scisignal.aba3043.
- Nogo‐B limits intima‐media thickening during mouse vein graft adaptationMuto A, Yi T, Fitzgerald T, Fancher T, Magri D, Yu J, Sessa W, Dardik A. Nogo‐B limits intima‐media thickening during mouse vein graft adaptation. The FASEB Journal 2008, 22: 174.4-174.4. DOI: 10.1096/fasebj.22.1_supplement.174.4.