Janice Jin Hwang, MD

• Ania Jastreboff
• Anika K. Anam
• Babar Khokhar
• Daniel F Vatner
• Elizabeth Sanchez Rangel
• Graeme Mason
• Harvey Kliman
• Jane O'Bryan
• Jason Bini
• Lauren Perley
• Lisa Parikh
• Seth Guller

Brain Diseases, Metabolic; Clinical Trials as Topic; Cognition Disorders; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Endocrinology; Metabolism; Neurosciences; Obesity; Translational Research, Biomedical; Neuroimaging; Functional Neuroimaging; Cognitive Neuroscience

• Pathophysiology and management of hypoglycemia in diabetesSanchez‐Rangel E, Deajon‐Jackson J, Hwang JJ. Pathophysiology and management of hypoglycemia in diabetes. Annals Of The New York Academy Of Sciences 2022, 1518: 25-46. PMID: 36202764, DOI: 10.1111/nyas.14904.
• Stress-level glucocorticoids increase fasting hunger and decrease cerebral blood flow in regions regulating eatingBini J, Parikh L, Lacadie C, Hwang JJ, Shah S, Rosenberg SB, Seo D, Lam K, Hamza M, De Aguiar RB, Constable T, Sherwin RS, Sinha R, Jastreboff AM. Stress-level glucocorticoids increase fasting hunger and decrease cerebral blood flow in regions regulating eating. NeuroImage Clinical 2022, 36: 103202. PMID: 36126514, PMCID: PMC9486604, DOI: 10.1016/j.nicl.2022.103202.
• Insulin increases placental triglyceride as a potential mechanism for fetal adiposity in maternal obesityAnam AK, Cooke KM, Dratver MB, O'Bryan JV, Perley LE, Guller SM, Hwang JJ, Taylor HS, Goedeke L, Kliman HJ, Vatner DF, Flannery CA. Insulin increases placental triglyceride as a potential mechanism for fetal adiposity in maternal obesity. Molecular Metabolism 2022, 64: 101574. PMID: 35970449, PMCID: PMC9440306, DOI: 10.1016/j.molmet.2022.101574.
• Reversibility of brain glucose kinetics in type 2 diabetes mellitusSanchez-Rangel E, Gunawan F, Jiang L, Savoye M, Dai F, Coppoli A, Rothman DL, Mason GF, Hwang JJ. Reversibility of brain glucose kinetics in type 2 diabetes mellitus. Diabetologia 2022, 65: 895-905. PMID: 35247067, PMCID: PMC8960594, DOI: 10.1007/s00125-022-05664-y.
• Food for ThoughtHwang JJ. Food for Thought. Journal Of Nutrition 2021, 151: 2089-2091. PMID: 34195820, DOI: 10.1093/jn/nxab210.
• Glycemic Variability and CNS Inflammation: Reviewing the ConnectionWatt C, Sanchez-Rangel E, Hwang JJ. Glycemic Variability and CNS Inflammation: Reviewing the Connection. Nutrients 2020, 12: 3906. PMID: 33371247, PMCID: PMC7766608, DOI: 10.3390/nu12123906.
• Characterizing the Effects of Diabetes and Obesity on Insulin and Leptin Levels amongst Pregnant WomenJohnson AW, Snegovskikh D, Parikh L, DeAguiar RB, Han CS, Hwang JJ. Characterizing the Effects of Diabetes and Obesity on Insulin and Leptin Levels amongst Pregnant Women. American Journal Of Perinatology 2020, 37: 1094-1101. PMID: 32120424, DOI: 10.1055/s-0040-1702988.
• Verapamil is a potential therapy for hypoglycaemic brain injuryHwang JJ, Sherwin RS. Verapamil is a potential therapy for hypoglycaemic brain injury. Nature Reviews Endocrinology 2018, 14: 443-444. PMID: 29967401, DOI: 10.1038/s41574-018-0056-7.
• Hypoglycemia unawareness in type 1 diabetes suppresses brain responses to hypoglycemiaHwang JJ, Parikh L, Lacadie C, Seo D, Lam W, Hamza M, Schmidt C, Dai F, Sejling AS, Belfort-DeAguiar R, Constable RT, Sinha R, Sherwin R. Hypoglycemia unawareness in type 1 diabetes suppresses brain responses to hypoglycemia. Journal Of Clinical Investigation 2018, 128: 1485-1495. PMID: 29381484, PMCID: PMC5873861, DOI: 10.1172/jci97696.
• Blunted rise in brain glucose levels during hyperglycemia in adults with obesity and T2DMHwang JJ, Jiang L, Hamza M, Rangel E, Dai F, Belfort-DeAguiar R, Parikh L, Koo BB, Rothman DL, Mason G, Sherwin RS. Blunted rise in brain glucose levels during hyperglycemia in adults with obesity and T2DM. JCI Insight 2017, 2: e95913. PMID: 29046482, PMCID: PMC5846903, DOI: 10.1172/jci.insight.95913.
• The human brain produces fructose from glucoseHwang JJ, Jiang L, Hamza M, Dai F, Belfort-DeAguiar R, Cline G, Rothman DL, Mason G, Sherwin RS. The human brain produces fructose from glucose. JCI Insight 2017, 2: e90508. PMID: 28239653, PMCID: PMC5313070, DOI: 10.1172/jci.insight.90508.
• Fructose Levels Are Markedly Elevated in Cerebrospinal Fluid Compared to Plasma in Pregnant WomenHwang JJ, Johnson A, Cline G, Belfort-DeAguiar R, Snegovskikh D, Khokhar B, Han CS, Sherwin RS. Fructose Levels Are Markedly Elevated in Cerebrospinal Fluid Compared to Plasma in Pregnant Women. PLOS ONE 2015, 10: e0128582. PMID: 26035307, PMCID: PMC4452737, DOI: 10.1371/journal.pone.0128582.
• Treatment of Endocrine Disorders in the Neuroscience Intensive Care UnitHwang JJ, Hwang DY. Treatment of Endocrine Disorders in the Neuroscience Intensive Care Unit. Current Treatment Options In Neurology 2014, 16: 271. PMID: 24390813, DOI: 10.1007/s11940-013-0271-4.