Hualong Bai, MD, PhD
Associate Research Scientist
Research & Publications
Biography
Research Summary
Under Dr.Dardik’s supervision, my researches focus on the healing process after patch angioplasty both in artery and vein, using different coating and drug delivery systems to inhibit neointimal hyperplasia, exploring the mechanism of arteriovenous fistula remolding, examining the application of hydrogel in vascular research, finding the potential meaningful natural vascular grafts. Now I am mainly focusing on the influence of immunoreaction in arteriovenous fistula maturation and remolding.
Coauthors
Selected Publications
- A Systematic Review and Meta-Analysis of Seasonal and Monthly Variability in the Incidence of Acute Aortic Dissection.Wu H, Wang Z, Li M, Liu Q, Liu W, Qiao Z, Bai T, Liu Y, Zhang C, Sun P, Wei S, Bai H. A Systematic Review and Meta-Analysis of Seasonal and Monthly Variability in the Incidence of Acute Aortic Dissection. Annals Of Vascular Surgery 2022, 85: 383-394. PMID: 35461996, DOI: 10.1016/j.avsg.2022.04.008.
- Outcomes of transcarotid artery revascularization: A systematic review.Wu H, Wang Z, Li M, Sun P, Wei S, Xie B, Zhang C, Zhang L, Bai H. Outcomes of transcarotid artery revascularization: A systematic review. Interventional Neuroradiology : Journal Of Peritherapeutic Neuroradiology, Surgical Procedures And Related Neurosciences 2022, 15910199221123283. PMID: 36039496, DOI: 10.1177/15910199221123283.
- Wood-Derived Vascular Patches Loaded With Rapamycin Inhibit Neointimal HyperplasiaXie B, Zhang L, Lou C, Wei S, Li J, Bai H, Dardik A. Wood-Derived Vascular Patches Loaded With Rapamycin Inhibit Neointimal Hyperplasia. Frontiers In Bioengineering And Biotechnology 2022, 10: 933505. PMID: 35928960, PMCID: PMC9343873, DOI: 10.3389/fbioe.2022.933505.
- Endothelial nitric oxide synthase (eNOS) mediates neointimal thickness in arteriovenous fistulae with different anastomotic angles in rats.Bai H, Wei S, Xie B, Wang Z, Li M, Qiao Z, Sun P, Wang W. Endothelial nitric oxide synthase (eNOS) mediates neointimal thickness in arteriovenous fistulae with different anastomotic angles in rats. The Journal Of Vascular Access 2022, 23: 403-411. PMID: 33619996, DOI: 10.1177/1129729821996537.
- Biodegraded PCl and gelatin fabricated vascular patch in rat aortic and inferior vena cava angioplasty.Bai H, Xie B, Li M, Sun P, Wei S, Zhang L, Zhang C. Biodegraded PCl and gelatin fabricated vascular patch in rat aortic and inferior vena cava angioplasty. Microvascular Research 2022, 141: 104314. PMID: 35032534, DOI: 10.1016/j.mvr.2022.104314.
- Intramural injection of pluronic gel loaded with drugs to alleviate arterial injuryBai H, Sun P, Wei S, Zhang L, Xing Y, Dardik A. Intramural injection of pluronic gel loaded with drugs to alleviate arterial injury. Microvascular Research 2022, 142: 104370. PMID: 35461875, DOI: 10.1016/j.mvr.2022.104370.
- PLGA Nanoparticle Rapamycin- or Necrostatin-1-Coated Sutures Inhibit Inflammatory Reactions after Arterial Closure in Rats.Zhang L, Wang W, Xie B, Sun P, Wei S, Wu H, Zhang C, Li J, Li Z, Bai H. PLGA Nanoparticle Rapamycin- or Necrostatin-1-Coated Sutures Inhibit Inflammatory Reactions after Arterial Closure in Rats. ACS Applied Bio Materials 2022, 5: 1501-1507. PMID: 35297594, DOI: 10.1021/acsabm.1c01256.
- Adventitial injection of HA/SA hydrogel loaded with PLGA rapamycin nanoparticle inhibits neointimal hyperplasia in a rat aortic wire injury model.Bai H, Wu H, Zhang L, Sun P, Liu Y, Xie B, Zhang C, Wei S, Wang W, Li J. Adventitial injection of HA/SA hydrogel loaded with PLGA rapamycin nanoparticle inhibits neointimal hyperplasia in a rat aortic wire injury model. Drug Delivery And Translational Research 2022 PMID: 35378720, DOI: 10.1007/s13346-022-01158-x.
- Egg Shell Membrane as an Alternative Vascular Patch for Arterial Angioplasty.Sun P, Yan S, Zhang L, Zhang C, Wu H, Wei S, Xie B, Wang X, Bai H. Egg Shell Membrane as an Alternative Vascular Patch for Arterial Angioplasty. Frontiers In Bioengineering And Biotechnology 2022, 10: 843590. PMID: 35372291, PMCID: PMC8971674, DOI: 10.3389/fbioe.2022.843590.
- The application of tissue-engineered fish swim bladder vascular graftBai H, Sun P, Wu H, Wei S, Xie B, Wang W, Hou Y, Li J, Dardik A, Li Z. The application of tissue-engineered fish swim bladder vascular graft. Communications Biology 2021, 4: 1153. PMID: 34611267, PMCID: PMC8492661, DOI: 10.1038/s42003-021-02696-9.
- Application of the Tissue-Engineered Plant Scaffold as a Vascular Patch.Bai H, Xie B, Wang Z, Li M, Sun P, Wei S, Wang W, Wu H, Bai L, Li J. Application of the Tissue-Engineered Plant Scaffold as a Vascular Patch. ACS Omega 2021, 6: 11595-11601. PMID: 34056315, PMCID: PMC8154004, DOI: 10.1021/acsomega.1c00804.
- Hydrogel-coated needles prevent puncture site bleedingWei S, Xu Y, Wang Z, Li M, Sun P, Xie B, Xing Y, Bai H, Kan Q, Li J, Dardik A. Hydrogel-coated needles prevent puncture site bleeding. Acta Biomaterialia 2021, 128: 305-313. PMID: 33894348, DOI: 10.1016/j.actbio.2021.04.004.
- Artery to vein configuration of arteriovenous fistula improves hemodynamics to increase maturation and patencyBai H, Sadaghianloo N, Gorecka J, Liu S, Ono S, Ramachandra AB, Bonnet S, Mazure NM, Declemy S, Humphrey JD, Dardik A. Artery to vein configuration of arteriovenous fistula improves hemodynamics to increase maturation and patency. Science Translational Medicine 2020, 12 PMID: 32817365, PMCID: PMC7705473, DOI: 10.1126/scitranslmed.aax7613.
- Transforming Growth Factor-&bgr;1 Inhibits Pseudoaneurysm Formation After Aortic Patch AngioplastyBai H, Lee JS, Hu H, Wang T, Isaji T, Liu S, Guo J, Liu H, Wolf K, Ono S, Guo X, Yatsula B, Xing Y, Fahmy TM, Dardik A. Transforming Growth Factor-&bgr;1 Inhibits Pseudoaneurysm Formation After Aortic Patch Angioplasty. Arteriosclerosis Thrombosis And Vascular Biology 2017, 38: 195-205. PMID: 29146747, PMCID: PMC5746454, DOI: 10.1161/atvbaha.117.310372.
- Polyester vascular patches acquire arterial or venous identity depending on their environmentBai H, Hu H, Guo J, Ige M, Wang T, Isaji T, Kudze T, Liu H, Yatsula B, Hashimoto T, Xing Y, Dardik A. Polyester vascular patches acquire arterial or venous identity depending on their environment. Journal Of Biomedical Materials Research Part A 2017, 105: 3422-3431. PMID: 28877393, PMCID: PMC5918420, DOI: 10.1002/jbm.a.36193.
- Patch Angioplasty in the Rat Aorta or Inferior Vena Cava.Bai H, Li X, Hashimoto T, Hu H, Foster TR, Hanisch JJ, Santana JM, Dardik A. Patch Angioplasty in the Rat Aorta or Inferior Vena Cava. Journal Of Visualized Experiments 2017 PMID: 28287579, PMCID: PMC5409337, DOI: 10.3791/55253.
- Covalent modification of pericardial patches for sustained rapamycin delivery inhibits venous neointimal hyperplasiaBai H, Lee JS, Chen E, Wang M, Xing Y, Fahmy TM, Dardik A. Covalent modification of pericardial patches for sustained rapamycin delivery inhibits venous neointimal hyperplasia. Scientific Reports 2017, 7: 40142. PMID: 28071663, PMCID: PMC5223139, DOI: 10.1038/srep40142.
- Pericardial patch venoplasty heals via attraction of venous progenitor cellsBai H, Wang M, Foster TR, Hu H, He H, Hashimoto T, Hanisch JJ, Santana JM, Xing Y, Dardik A. Pericardial patch venoplasty heals via attraction of venous progenitor cells. Physiological Reports 2016, 4: e12841. PMID: 27354544, PMCID: PMC4923240, DOI: 10.14814/phy2.12841.