David Moore, MD, PhD
Associate Professor of Psychiatry; Director, VISN 1 Clinical Resource Hub; Chief, Clinical Resource Hub Service Line; Director, National Expert Consultation and Specialty Services - Mental Health
Research & Publications
Biography
News
Coauthors
Selected Publications
- Implementing a Successful Tele-Nephrology Program for Rural VeteransBonegio R, Tuozzo K, Rifkin I, Kroll-Desrosiers A, Crowley S, Mattocks K, Moore D. Implementing a Successful Tele-Nephrology Program for Rural Veterans. Journal Of The American Society Of Nephrology 2023, 34: 729-729. DOI: 10.1681/asn.20233411s1729c.
- The Tyrosine Kinase c-Src Specifically Binds to the Active Integrin αIIbβ3 to Initiate Outside-in Signaling in Platelets.Wu Y, Span LM, Nygren P, Zhu H, Moore DT, Cheng H, Roder H, DeGrado WF, Bennett JS. The Tyrosine Kinase c-Src Specifically Binds to the Active Integrin αIIbβ3 to Initiate Outside-in Signaling in Platelets. J Biol Chem 2015, 290: 15825-15834. PMID: 25947380, DOI: 10.1074/jbc.M115.648428.
- Affinity of talin-1 for the β3-integrin cytosolic domain is modulated by its phospholipid bilayer environment.Moore DT, Nygren P, Jo H, Boesze-Battaglia K, Bennett JS, DeGrado WF. Affinity of talin-1 for the β3-integrin cytosolic domain is modulated by its phospholipid bilayer environment. Proc Natl Acad Sci U S A 2012, 109: 793-8. PMID: 22210111, DOI: 10.1073/pnas.1117220108.
- Computational design of a β-peptide that targets transmembrane helices.Shandler SJ, Korendovych IV, Moore DT, Smith-Dupont KB, Streu CN, Litvinov RI, Billings PC, Gai F, Bennett JS, DeGrado WF. Computational design of a β-peptide that targets transmembrane helices. J Am Chem Soc 2011, 133: 12378-81. PMID: 21780757, DOI: 10.1021/ja204215f.
- Transmembrane communication: general principles and lessons from the structure and function of the M2 proton channel, K⁺ channels, and integrin receptors.Grigoryan G, Moore DT, DeGrado WF. Transmembrane communication: general principles and lessons from the structure and function of the M2 proton channel, K⁺ channels, and integrin receptors. Annu Rev Biochem 2011, 80: 211-37. PMID: 21548783, DOI: 10.1146/annurev-biochem-091008-152423.
- NMR analysis of the alphaIIb beta3 cytoplasmic interaction suggests a mechanism for integrin regulation.Metcalf DG, Moore DT, Wu Y, Kielec JM, Molnar K, Valentine KG, Wand AJ, Bennett JS, DeGrado WF. NMR analysis of the alphaIIb beta3 cytoplasmic interaction suggests a mechanism for integrin regulation. Proc Natl Acad Sci U S A 2010, 107: 22481-6. PMID: 21156831, DOI: 10.1073/pnas.1015545107.
- Regulation of platelet beta 3 integrins.Bennett JS, Moore DT. Regulation of platelet beta 3 integrins. Haematologica 2010, 95: 1049-51. PMID: 20595101, DOI: 10.3324/haematol.2010.024893.
- Protein-protein interactions in the membrane: sequence, structural, and biological motifs.Moore DT, Berger BW, DeGrado WF. Protein-protein interactions in the membrane: sequence, structural, and biological motifs. Structure 2008, 16: 991-1001. PMID: 18611372, DOI: 10.1016/j.str.2008.05.007.
- Activation of platelet alphaIIbbeta3 by an exogenous peptide corresponding to the transmembrane domain of alphaIIb.Yin H, Litvinov RI, Vilaire G, Zhu H, Li W, Caputo GA, Moore DT, Lear JD, Weisel JW, Degrado WF, Bennett JS. Activation of platelet alphaIIbbeta3 by an exogenous peptide corresponding to the transmembrane domain of alphaIIb. J Biol Chem 2006, 281: 36732-41. PMID: 17032655, DOI: 10.1074/jbc.M605877200.
- Arylamide derivatives as allosteric inhibitors of the integrin alpha2beta1/type I collagen interaction.Yin H, Gerlach LO, Miller MW, Moore DT, Liu D, Vilaire G, Bennett JS, DeGrado WF. Arylamide derivatives as allosteric inhibitors of the integrin alpha2beta1/type I collagen interaction. Bioorg Med Chem Lett 2006, 16: 3380-2. PMID: 16678410, DOI: 10.1016/j.bmcl.2006.04.037.
- Highly enantioselective phenylacetylene additions to both aliphatic and aromatic aldehydes.Gao G, Moore D, Xie RG, Pu L. Highly enantioselective phenylacetylene additions to both aliphatic and aromatic aldehydes. Org Lett 2002, 4: 4143-6. PMID: 12423107, DOI: 10.1021/ol026921r.
- BINOL-catalyzed highly enantioselective terminal alkyne additions to aromatic aldehydes.Moore D, Pu L. BINOL-catalyzed highly enantioselective terminal alkyne additions to aromatic aldehydes. Org Lett 2002, 4: 1855-7. PMID: 12027631, DOI: 10.1021/ol025825n.