Stanley Hudnall, MD
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Pathology
Primary
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About
Titles
Professor Emeritus of Pathology
Biography
Dr. Hudnall is an AP/CP board certified hematopathologist with a special interest in lymphoproliferative disorders and the role of chronic inflammation and tumor-infiltrating lymphocytes and monocytes in tumor progression. Dr. Hudnall is also interested in the role of infectious agents in lymphoproliferative disorders, with a special interest in herpes viruses.
Appointments
Pathology
EmeritusPrimary
Other Departments & Organizations
Education & Training
- Post-doctoral fellow
- Brigham & Women's Hospital (1984)
- Resident
- Yale-New Haven Hospital (1982)
- Resident
- Yale-New Haven Hospital (1980)
- MD
- Medical University of South Carolina (1978)
Board Certifications
Hematology (Pathology)
- Certification Organization
- AB of Pathology
- Original Certification Date
- 1998
Anatomic & Clinical Pathology
- Certification Organization
- AB of Pathology
- Original Certification Date
- 1983
Research
Overview
Genetics of Hodgkin lymphoma
HHV-6 in Hodgkin lymphoma
Medical Subject Headings (MeSH)
Bone Marrow Examination; Epstein-Barr Virus Infections; Hemic and Lymphatic Diseases; Herpesviridae; Herpesvirus 6, Human; Hodgkin Disease; Immune System Diseases; Immunophenotyping; Macrophages; Molecular Probe Techniques; Monocytes; Tumor Escape; Virus Diseases; Virus Latency
Research at a Glance
Yale Co-Authors
Frequent collaborators of Stanley Hudnall's published research.
Publications Timeline
A big-picture view of Stanley Hudnall's research output by year.
Research Interests
Research topics Stanley Hudnall is interested in exploring.
Alexa Siddon, MD
Peining Li, PhD
45Publications
1,109Citations
Epstein-Barr Virus Infections
Hodgkin Disease
Immunophenotyping
Herpesviridae
Herpesvirus 6, Human
Publications
2019
Pocket Guide to Diagnostic Hematopathology
Hudnall S, Much M, Siddon A. Pocket Guide to Diagnostic Hematopathology. 2019 DOI: 10.1007/978-3-030-10630-0.BooksCitationsAltmetric
2017
Pathology of Hodgkin Lymphoma
Hudnall S. Pathology of Hodgkin Lymphoma. Molecular Pathology Library 2017, 13-34. DOI: 10.1007/978-3-319-68094-1_2.Peer-Reviewed Original ResearchCitationsConceptsReed-Sternberg cellsNodular lymphocyte predominant Hodgkin lymphomaLymphocyte predominant Hodgkin lymphomaPredominant Hodgkin lymphomaHodgkin's lymphomaClassical Reed-Sternberg cellsB cellsLP cellsMediastinal gray zone lymphomaCD4 T cellsMantle zone B cellsGray zone lymphomaReactive inflammatory infiltrateGerminal center B lymphocytesB-cell originClassical Hodgkin lymphomaB-cell immunophenotypeClonal cellsMedium-sized mononuclear cellsInflammatory infiltrateClinical featuresCastleman's diseaseHistopathologic featuresImmunophenotypic featuresReactive infiltrate
2016
Recurrent genetic defects in classical Hodgkin lymphoma cell lines
Hudnall SD, Meng H, Lozovatsky L, Li P, Strout M, Kleinstein SH. Recurrent genetic defects in classical Hodgkin lymphoma cell lines. Leukemia & Lymphoma 2016, 57: 2890-2900. PMID: 27121023, DOI: 10.1080/10428194.2016.1177179.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMitosis-related genesSingle nucleotide variantsCHL cell linesCell linesRecurrent genetic defectsPathogenic single nucleotide variantsHL cell linesMitotic genesChromosome duplicationClassical Hodgkin lymphoma cell linesGenomic instabilityGenetic analysisWhole-exome sequencingNucleotide variantsGenesHodgkin's lymphoma cell linesLymphoma cell linesNumber variantsKaryotypic analysisGenetic defectsWealth of informationPoor growthVariantsDuplicationLines
2014
Epstein–Barr Virus: Epidemiology and Clinical Features of Related Cancer
Hudnall S. Epstein–Barr Virus: Epidemiology and Clinical Features of Related Cancer. 2014, 25-50. DOI: 10.1007/978-1-4939-0870-7_3.Peer-Reviewed Original ResearchCitationsConceptsCell lymphomaEBV latency genesRisk of EBVEBV-positive lymphomasNK-cell lymphomasEpstein-Barr virusEndemic Burkitt lymphomaEBV gene expressionB-cell lymphomaHuman malignant tumorsImmunodeficiency-associated lymphomasApparent immunodeficiencyEBV infectionFalciparum malariaLymphoepithelial carcinomaOrgan failureClinical featuresImmunocompetent hostsLikely multifactorialSeroprevalence ratesImmunodeficient hostsMalignant tumorsSevere diseaseNasopharyngeal carcinomaBurkitt's lymphomaHuman Cancer Virology: An Historical Review
Hudnall S. Human Cancer Virology: An Historical Review. 2014, 1-6. DOI: 10.1007/978-1-4939-0870-7_1.Peer-Reviewed Original ResearchConceptsMerkel cell carcinomaCell carcinomaHepatocellular carcinomaAdult T-cell leukemia/lymphomaT-cell leukemia/lymphomaCell leukemia/lymphomaBurkitt's lymphoma tissueEpstein-Barr virusHepatitis B virusLeukemia/lymphomaHuman cancer virusesKaposi's sarcoma tissueRetrovirus HTLV-1Tumor-inducing propertiesCervical cancerHuman papillomavirusB virusHepatitis virusLymphoma tissuesHTLV-1CarcinomaSarcoma tissuesWart tissueSophisticated molecular techniquesCancer virusesEpstein–Barr Virus: Pathogenesis and Host Immune Response
Hudnall S. Epstein–Barr Virus: Pathogenesis and Host Immune Response. 2014, 7-24. DOI: 10.1007/978-1-4939-0870-7_2.Peer-Reviewed Original ResearchCitationsConceptsEpstein-Barr virusLarge double-stranded DNA genomeDouble-stranded DNA genomeInfected cellsLytic genesAnti-viral immune responsesTerminal repeat unitsCircular episomal formVirion structural componentsLinear DNA moleculesCellular S phaseLytic replicationLatent genesB cellsImmune responseRepeat unitsImmune recognitionReplication programDaughter cellsInternal repeat unitsDNA genomeGrowth signalsIcosahedral capsidTegument proteinsEBV-specific cytotoxic T cells
2012
Rare Subtypes of Extranodal T-Cell Lymphoma
Lansigan F, Hudnall S, Foss F. Rare Subtypes of Extranodal T-Cell Lymphoma. Contemporary Hematology 2012, 105-112. DOI: 10.1007/978-1-62703-170-7_7.Peer-Reviewed Original ResearchConceptsT-cell lymphomaPoor outcomePanniculitis-like T-cell lymphomaExtranodal T-cell lymphomasCytotoxic T-cell lymphomaHepatosplenic T-cell lymphomaRare T-cell lymphomaAggressive T-cell lymphomaConventional therapeutic approachesInflammatory panniculitisImmunosuppressive therapyExcellent prognosisAutoimmune disordersRare subtypeCeliac sprueTissue trophismTherapeutic approachesNew agentsLymphomaIsochromosome 7qMorphologic typesDisordersOutcomesPanniculitisPrognosisHuman herpesvirus 6 positive Reed–Sternberg cells in nodular sclerosis Hodgkin lymphoma
Siddon A, Lozovatsky L, Mohamed A, Hudnall SD. Human herpesvirus 6 positive Reed–Sternberg cells in nodular sclerosis Hodgkin lymphoma. British Journal Of Haematology 2012, 158: 635-643. PMID: 22757777, DOI: 10.1111/j.1365-2141.2012.09206.x.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsMeSH KeywordsAdolescentAdultAge FactorsAgedBlotting, WesternCell Line, TumorDNA, ViralEpstein-Barr Virus InfectionsFemaleHerpesvirus 4, HumanHerpesvirus 6, HumanHodgkin DiseaseHumansImmunohistochemistryLymphoma, FollicularMaleMiddle AgedPolymerase Chain ReactionReed-Sternberg CellsRoseolovirus InfectionsSclerosisYoung AdultConceptsNodular sclerosis Hodgkin lymphomaNodular sclerosis HLHHV-6 DNAEpstein-Barr virusHHV-6Hodgkin's lymphomaReed-Sternberg cellsPolymerase chain reactionRS cellsNSHL casesEBV-negative diseaseReactive lymphoid hyperplasiaClassical Hodgkin lymphomaBi-modal age distributionHHV-6 genomeYounger patientsInfectious etiologyLymphoid hyperplasiaPCR positivityYounger ageImmunohistochemistryMost casesConflicting resultsChain reactionCD30
2011
CHAPTER 56 Human Herpesvirus Infections
Hudnall S, Stanberry L, Griffiths P. CHAPTER 56 Human Herpesvirus Infections. 2011, 355-368. DOI: 10.1016/b978-0-7020-3935-5.00056-2.Peer-Reviewed Original Research
2008
Herpesvirus prevalence and viral load in healthy blood donors by quantitative real‐time polymerase chain reaction
Hudnall SD, Chen T, Allison P, Tyring SK, Heath A. Herpesvirus prevalence and viral load in healthy blood donors by quantitative real‐time polymerase chain reaction. Transfusion 2008, 48: 1180-1187. PMID: 18422852, DOI: 10.1111/j.1537-2995.2008.01685.x.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsEpstein-Barr virusVaricella-zoster virusHealthy adult blood donorsAdult blood donorsBlood donorsHHV-6Human herpesvirusesViral loadHHV-7Primary infectionDonor samplesMedian viral loadHHV-6 DNAHealthy blood donorsHHV-8 DNAViral DNA loadReal-time polymerase chain reactionQuantitative real-time polymerase chain reactionHerpes simplex virus 1Single-donor samplesSimplex virus 1Polymerase chain reaction assaysReal-time polymerase chain reaction assaysTransfusion recipientsActive infection
Academic Achievements and Community Involvement
activity President
Professional OrganizationsBinford-Dammin Society of Infectious Disease PathologistsDetails03/01/2014 - 03/01/2015DescriptionPresidentactivity Chairperson
Professional OrganizationsUniversity of Texas Medical BranchDetails07/01/2008 - 07/01/2009DescriptionChair of Faculty Senatehonor Phi Beta Kappa
National AwardUniversity of South CarolinaDetails07/01/1972United Stateshonor Best lecturer award (8 times) 1999-2009
Yale School of Medicine AwardUTMB Pathology DepartmentDetailsUnited Stateshonor Carolina Scholar
Yale University AwardUniversity of South CarolinaDetails07/01/1969United States
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