Cihan Halicigil
HCLD, PhD, MSc
Assistant Professor of Obstetrics, Gynecology and Reproductive Sciences; Laboratory Director, Yale Fertility Center LGBTQI+ Program Contact; IVF Laboratory Director, Yale Medicine Greenwich Fertility
Research & Publications
Biography
Locations
Coauthors
Selected Publications
- Understanding how space travel affects the female reproductive system to the Moon and beyondMathyk B, Imudia A, Quaas A, Halicigil C, Karouia F, Avci P, Nelson N, Guzeloglu-Kayisli O, Denbo M, Sanders L, Scott R, Basar M, Guevara-Cerdán A, Strug M, Monseur B, Kayisli U, Szewczyk N, Mason C, Young S, Tasoglu S, Costes S, Beheshti A. Understanding how space travel affects the female reproductive system to the Moon and beyond. Npj Women's Health 2024, 2: 20. DOI: 10.1038/s44294-024-00009-z.
- UTILIZATION OF COMBINING MICROSCOPIC TESTICULAR SPERM EXTRACTION (MTESE) AND DENSITY GRADIENT PROCESSING TO OPTIMIZE SPERM RETRIEVAL AND PREGNANCY OUTCOMES IN MEN WITH NONOBSTRUCTIVE AZOOSPERMIA (NOA)Deebel N, Nikmehr B, Hingu J, O'Connor C, Ruble R, Song Y, Vuruskan A, Halicigil C, Devineni A, Howards S, Yalcinkaya T, Sadri-Ardekani H. UTILIZATION OF COMBINING MICROSCOPIC TESTICULAR SPERM EXTRACTION (MTESE) AND DENSITY GRADIENT PROCESSING TO OPTIMIZE SPERM RETRIEVAL AND PREGNANCY OUTCOMES IN MEN WITH NONOBSTRUCTIVE AZOOSPERMIA (NOA). Fertility And Sterility 2023, 120: e246-e247. DOI: 10.1016/j.fertnstert.2023.08.695.
- RAPID VS STANDARD: ULTRAFAST WARMING OF VITRIFIED BLASTOCYSTS DOES NOT ALTER BLASTOCYST COMPETENCY AND STRESS RESPONSEChaplia O, Ergun Y, Nichols-Burns S, Halicigil C, Basar M. RAPID VS STANDARD: ULTRAFAST WARMING OF VITRIFIED BLASTOCYSTS DOES NOT ALTER BLASTOCYST COMPETENCY AND STRESS RESPONSE. Fertility And Sterility 2023, 120: e204-e205. DOI: 10.1016/j.fertnstert.2023.08.589.
- MP43-02 COMBINATION OF MICROSCOPIC TESTICULAR SPERM EXTRACTION (MTESE) AND DENSITY GRADIENT PROCESSING TO OPTIMIZE SPERM RETRIEVAL AND PREGNANCY OUTCOMES IN MEN WITH NONOBSTRUCTIVE AZOOSPERMIA (NOA)Deebel N, Nikmehr B, Hingu J, O'Connor C, Ruble R, Song Y, Vuruskan A, Devineni A, Halicigil C, Howards S, Yalcinkaya T, Sadri-Ardekani H. MP43-02 COMBINATION OF MICROSCOPIC TESTICULAR SPERM EXTRACTION (MTESE) AND DENSITY GRADIENT PROCESSING TO OPTIMIZE SPERM RETRIEVAL AND PREGNANCY OUTCOMES IN MEN WITH NONOBSTRUCTIVE AZOOSPERMIA (NOA). Journal Of Urology 2023, 209: e601. DOI: 10.1097/ju.0000000000003289.02.
- Automation in Clinical Embryology Laboratories — What is Next?Halicigil C, Ogut M, Demirci U. Automation in Clinical Embryology Laboratories — What is Next? 2022, 105-126. DOI: 10.1142/9789811226106_0006.
- FROM OOCYTES TO A LIVE BIRTH: DOES PGT-A HELP OR HARM?Sabbagh R, S N, Halicigil C, Quinlan J, Shah J, Korkidakis A, Penzias A, Patrizio P, Sakkas D. FROM OOCYTES TO A LIVE BIRTH: DOES PGT-A HELP OR HARM? Fertility And Sterility 2022, 118: e10-e11. DOI: 10.1016/j.fertnstert.2022.09.232.
- ICSI IS ASSOCIATED WITH LOWER BLASTULATION RATES COMPARED TO CONVENTIONAL IVF AMONG COUPLES WITH NON-MALE FACTOR INFERTILITY AND LOW OOCYTE YIELDBeroukhim G, Seifer D, Chaplia O, Nichols-Burns S, Basar M, Halicigil C. ICSI IS ASSOCIATED WITH LOWER BLASTULATION RATES COMPARED TO CONVENTIONAL IVF AMONG COUPLES WITH NON-MALE FACTOR INFERTILITY AND LOW OOCYTE YIELD. Fertility And Sterility 2022, 118: e143. DOI: 10.1016/j.fertnstert.2022.08.419.
- Disposable paper-based microfluidics for fertility testingSarabi MR, Yigci D, Alseed MM, Mathyk BA, Ata B, Halicigil C, Tasoglu S. Disposable paper-based microfluidics for fertility testing. IScience 2022, 25: 104986. PMID: 36105592, PMCID: PMC9465368, DOI: 10.1016/j.isci.2022.104986.
- Optimum identification of round spermatid in men with non‐obstructive azoospermia: A commentaryBradshaw AW, Nikmehr B, Halicigil C, Stogner‐Underwood K, Sadri‐Ardekani H. Optimum identification of round spermatid in men with non‐obstructive azoospermia: A commentary. Andrology 2021, 9: 1817-1818. PMID: 34618410, DOI: 10.1111/andr.13113.
- MP44-15 EFFICIENT SELECTION METHOD FOR HUMAN ROUND SPERMATID IN TESE NEGATIVE MENNikmehr* B, Halicigil C, Pettenati M, Atala A, Sadri-Ardekani H. MP44-15 EFFICIENT SELECTION METHOD FOR HUMAN ROUND SPERMATID IN TESE NEGATIVE MEN. Journal Of Urology 2020, 203 DOI: 10.1097/ju.0000000000000899.015.
- Continuous monitoring of incubator and cryotank parametersKoduru A, Devineni S, Halicigil C, Mesen T, Yalcinkaya T, Angle M. Continuous monitoring of incubator and cryotank parameters. Reproductive BioMedicine Online 2019, 39: e8-e9. DOI: 10.1016/j.rbmo.2019.07.019.
- Multi-center study: innovative control of ambient air quality in multiple IVF laboratories is associated with statistically significant improvements in clinical outcomes - analysis of 5319 cyclesPalter S, DiPaola K, Sparks A, Degelos S, Koulianos G, Young J, Halicigil C, Yalcinkaya T, She E, Bartolucci A. Multi-center study: innovative control of ambient air quality in multiple IVF laboratories is associated with statistically significant improvements in clinical outcomes - analysis of 5319 cycles. Fertility And Sterility 2016, 106: e27-e28. DOI: 10.1016/j.fertnstert.2016.07.090.
- The variations of AMH serum concentrations after COH treatmentLeylek O, Tiras B, Halicigil C, Saltik A, Kavci N. The variations of AMH serum concentrations after COH treatment. Fertility And Sterility 2014, 102: e147. DOI: 10.1016/j.fertnstert.2014.07.505.
- The variations of AMH serum concentrations after COH treatmentFertility and Sterility Volume 102, Issue 3, Supplement, September 2014, Page e147
- Relationship of human chorionic gonadotropin levels after oocyte triggering with oocyte maturation and IVF outcomesHuman Reproduction, Volume 29, Issue suppl_1, 1 July 2014, Pages i1–i389
- Does single dose GnRH agonist administration after oocyte pick-up in antagonist cycles improve endometrial receptivity and pregnancy rates?Tiras B, Leylek O, Halicigil C, Saltik A, Kavci N. Does single dose GnRH agonist administration after oocyte pick-up in antagonist cycles improve endometrial receptivity and pregnancy rates? Fertility And Sterility 2013, 100: s59-s60. DOI: 10.1016/j.fertnstert.2013.07.1864.
- Early pregnancyZeadna A, Holzer H, Son W, Demirtas E, Reinblatt S, Dahan M, Colleselli V, D'Costa E, Wildt L, Seeber B, Kashevarova A, Skryabin N, Nikitina T, Lebedev I, Bordignon P, Mugione A, Vanni V, Vigano P, Papaleo E, Candiani M, Somigliana E, Amodio G, Gregori S, Guo Y, Li R, Wang L, Chen S, Chen X, Guo W, Ye D, Liu Y, Renzini M, Dal Canto M, Coticchio G, Comi R, Brigante C, Caliari I, Brambillasca F, Merola M, Lain M, Turchi D, Karagouga G, Sottocornola M, Fadini R, Wekker M, Mol F, van Wely M, Ankum W, Mol B, van der Veen F, Hajenius P, van Mello N, Verlengia C, Alviggi E, Rampini M, Alfano P, Pergolini I, Marconi D, Iacobelli N, Muzi M, Gelli G, Alviggi C, Colicchia A, Herraiz-Nicuesa L, Tejera-Alhambra M, Garcia-Segovia A, Ramos-Medina R, Alonso B, Gil-Pulido J, Martin L, Caballero M, Rodriguez-Mahou M, Sanchez-Ramon S, de Jong P, Kaandorp S, Di Nisio M, Goddijn M, Middeldorp S, Lledo B, Turienzo A, Ortiz J, Morales R, Ten J, Llacer J, Bernabeu R, Ramos-Medina R, Garcia-Segovia A, Gil J, Leon J, Alonso B, Tejera-Alhambra M, Seyfferth A, Aguaron A, Alonso J, de Albornoz E, Carbone J, Caballero P, Fernandez-Cruz E, Ortiz-Quintana L, Sanchez-Ramon S, Lou Y, Jin F, Zheng Y, Li L, Le F, Wang L, Liu S, Pan P, Hu C, Akoum A, Bourdiec A, Shao R, Rao C, Scarpellini F, Sbracia M, Jancar N, Bokal E, Ban-Frangez H, Drobnic S, Korosec S, Pinter B, Salamun V, Yamaguchi M, Honda R, Uchino K, Ohba T, Katabuchi H, Leylek O, Tiras B, Saltik A, Halicigil C, Kavci N, Wiser A, Gilbert A, Nahum R, Orvieto R, Hass J, Hourvitz A, Weissman A, Younes G, Dirnfeld M, Hershko A, Shulma A, Holzer H, Shalom-Paz E, Tulandi T, O'Neill S, Agerbo E, Kenny L, Henriksen T, Kearney P, Greene R, Mortensen P, Khashan A, Talaulikar V, Bax B, Manyonda I, Van Mello N, Mol F, Hajenius P, Ankum W, Mol B, van der Veen F, van Wely M. Early pregnancy. Human Reproduction 2013, 28: i139-i149. DOI: 10.1093/humrep/det209.
- P-34 Feasibility for preimplantation genetic diagnosis after single cell biopsy in an infertile couple with calpainopathyArikan G, Mutlu A, Yakicier M, Halicigil C, Tiras B. P-34 Feasibility for preimplantation genetic diagnosis after single cell biopsy in an infertile couple with calpainopathy. Reproductive BioMedicine Online 2013, 26: s40. DOI: 10.1016/s1472-6483(13)60097-8.
- Does single dose GnRH agonist administration after oocyte pick-up in antagonist cycles improve endometrial receptivity and pregnancy rates?Fertility and Sterility Volume 100, Issue 3, Supplement, September 2013, Pages S59-S60
- Feasibility for preimplantation genetic diagnosis after single cell biopsy in an infertile couple with calpainopathyReproductive Biomedicine Online 26: S40
- Preimplantation genetic testing after single cell biopsy in a consanguinous couple with calpainopathy2th International Conference on Preimplantation Genetic Diagnosis May 8-11, 2013. İstanbul.
- The comparison of five percent and ten percent oxygen concentration in human embryo culture in terms of IVF /ICSI outcomeHuman Reproduction, Volume 22, Issue suppl_1, 1 July 2007, Pages i21–i23,
- Comparison of glass syringe (Hamilton) and tuberculin syringe (Braun, F-inject) for embryo transfer in IVF/ICSI cyclesHuman Reproduction, Volume 22, Issue suppl_1, 1 July 2007, Pages i139–i143
- P-283 Cook® and Wallace® soft embryo transfer catheters yield comparable pregnancy out comes following intracytoplasmic sperm injection (ICSI) and embryo transferKaraman Y, Gunenc Z, Bingol B, Gunduz S, Avcil F, Halicigil C. P-283 Cook® and Wallace® soft embryo transfer catheters yield comparable pregnancy out comes following intracytoplasmic sperm injection (ICSI) and embryo transfer. Fertility And Sterility 2006, 86: s240. DOI: 10.1016/j.fertnstert.2006.07.637.
- P-282 Embryo transfer (ET) outcome of day 2 and day 3 transfers in patients less than 7 metaphase two oocytes in two different age groups in intracytoplasmic sperm injection (ICSI) cyclesHalicigil C, Gunenc Z, Bingol B, Gunduz S, Avcil F, Karaman Y. P-282 Embryo transfer (ET) outcome of day 2 and day 3 transfers in patients less than 7 metaphase two oocytes in two different age groups in intracytoplasmic sperm injection (ICSI) cycles. Fertility And Sterility 2006, 86: s240. DOI: 10.1016/j.fertnstert.2006.07.636.
- Cook® and Wallace® soft embryo transfer catheters yield comparable pregnancy out comes following intracytoplasmic sperm injection (ICSI) and embryo transferFertility and Sterility Volume 86, Issue 3, Supplement, September 2006, Page S240
- Comparison of two different sequential culture media systems in ICSI cyclesHuman Reproduction, Volume 21, Issue suppl_1, 1 June 2006, Pages i158–i159,
- E2 drop during luteal-long leuprolide acetate protocol does not have a negative impact on ICSI and ET outcomeSaygili-Yilmaz E, Esinler I, Bozdag G, Halicigil C, Aybar F, Yarali H. E2 drop during luteal-long leuprolide acetate protocol does not have a negative impact on ICSI and ET outcome. Fertility And Sterility 2004, 82: s210-s211. DOI: 10.1016/j.fertnstert.2004.07.556.
- The ICSI low responder: acceptable pregnancy rates with 3-5 oocytesHuman Reproduction, Volume 19, Issue suppl_1, 1 June 2004, Pages I69–I71
- Does the presence of polycystic ovaries affect the ICSI out come?Human Reproduction, Volume 19, Issue suppl_1, 1 June 2004, Pages I105–I112
- Combined Cytogenetic and Y Chromosome Microdeletion Screening of Turkish Males With Severe Male Factor infertility4 th Cytogenetics Conference. Bologna / Italy.
- Prior diagnostic testicle biopsy cannot highly predict the success or failure of retrieval of sperm at testicular sperm extractionHuman Reproduction, Volume 17, Issue suppl_1, 1 July 2002, Pages 99–111
- Does the oolemma breakage pattern during ICSI affect fertilization rates and embryo quality?Human Reproduction, Volume 17, Issue suppl_1, 1 July 2002, Pages 111–163, https://doi.org/10.1093/humrep/17.suppl_1.111
- Does depth of embryo transfer without ultrasonographic guidance predict success in ICSI cycles?Human Reproduction, Volume 17, Issue suppl_1, 1 July 2002, Pages 111–163
- Crinone and i.m. progesterone yield comparable pregnancy rates following ICSI and embryo transferHuman Reproduction, Volume 17, Issue suppl_1, 1 July 2002, Pages 200–205
- Affinity interaction of hydroxypyruvate reductase from Methylophilus spp. with Cibacron blue F3GA-derived poly(HEMA EGDMA) microspheres: partial purification and characterizationArica M, Halıcıgil C, Alaeddinoğlu G, Denizli A. Affinity interaction of hydroxypyruvate reductase from Methylophilus spp. with Cibacron blue F3GA-derived poly(HEMA EGDMA) microspheres: partial purification and characterization. Process Biochemistry 1999, 34: 375-381. DOI: 10.1016/s0032-9592(98)00104-6.
- Biodegradation of aldicarb in a packed-bed reactor by immobilized MethylosinusKök F, Arıca M, Halıcıgil C, Alaeddinoğlu G, Hasırcı V. Biodegradation of aldicarb in a packed-bed reactor by immobilized Methylosinus. Enzyme And Microbial Technology 1999, 24: 291-296. DOI: 10.1016/s0141-0229(98)00124-0.
- Assimilation of Methylamine arising from the degradation of the pesticide aldicarb by a methylotrophic Methylosinus sp.The 7th Symposium of Scottish Microbiological Society, 6 April 1998, University of Strathclyde.
- Bacterial Degradation and Controlled Release of Aldicarb Intern.Symp. Control.Rel.Mater.18-21 July, 1995, Ottawa, Canada