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Charles Dela Cruz, MD, PhD

Associate Professor Adjunct; Director, Center for Pulmonary Infection Research and Treatment (CPIRT)

Contact Information

Charles Dela Cruz, MD, PhD

Office Location

Mailing Address

  • Pulmonary, Critical Care & Sleep Medicine

    PO Box 208057, 300 Cedar Street

    New Haven, CT 06520-8057

    United States

Research Summary

Our group is committed to innovative and cutting-edge basic, translational and clinical research that will further our understanding of pulmonary infections and lead to effective diagnosis and treatment. Current therapies for pulmonary infections have largely focused on the use of antibiotics and have led to the rapid emergence of drug resistance and hypervirulent strains. We will address current priorities in novel strategies in studying the host and the pathogen for both acute and chronic pulmonary infections. The research endeavors are aimed at delineating the basic mechanisms by which pulmonary pathogens cause disease as well as applying scientific advances to promote patient diagnosis and treatment

Our work is focused in both explorative and targeted research relevant to pulmonary infection and immunity in 3 specific areas:

(1) To explore the basic science of key host-microbe molecular and cellular interactions in the lung;

(2) To investigate and define the mechanisms of infections which either cause or exacerbate acute / chronic lung diseases using both basic and translational approaches;

(3) To utilize and develop novel technologies that will make it possible to better diagnose and treat pernicious lung infections.


Research Interests

Respiratory Tract Infections; Pulmonary Disease, Chronic Obstructive

Selected Publications