Caihong Qiu, PhD

• Anna Szekely
• Daniel Jacoby
• Diane Krause
• Emanuela Bruscia
• Haifan Lin
• In-Hyun Park
• Jason Thomson
• Jenny Huanjiao Zhou
• Jun Lu
• Lawrence Rizzolo
• Lawrence Young
• Mei Zhong
• Muhammad Riaz
• Ron Adelman
• Stephanie Massaro
• Stuart Campbell
• Xiao-Bing Gao
• Yibing Qyang

Cell Biology; Embryonic Stem Cells

• Muscle LIM Protein Force-Sensing Mediates Sarcomeric Biomechanical Signaling in Human Familial Hypertrophic CardiomyopathyRiaz M, Park J, Sewanan LR, Ren Y, Schwan J, Das SK, Pomianowski PT, Huang Y, Ellis MW, Luo J, Liu J, Song L, Chen IP, Qiu C, Yazawa M, Tellides G, Hwa J, Young LH, Yang L, Marboe CC, Jacoby DL, Campbell SG, Qyang Y. Muscle LIM Protein Force-Sensing Mediates Sarcomeric Biomechanical Signaling in Human Familial Hypertrophic Cardiomyopathy. Circulation 2022, 145: 1238-1253. PMID: 35384713, PMCID: PMC9109819, DOI: 10.1161/circulationaha.121.056265.
• The role of FYCO1-dependent autophagy in lens fiber cell differentiationKhan SY, Ali M, Kabir F, Na CH, Delannoy M, Ma Y, Qiu C, Costello MJ, Hejtmancik JF, Riazuddin SA. The role of FYCO1-dependent autophagy in lens fiber cell differentiation. Autophagy 2022, 18: 2198-2215. PMID: 35343376, PMCID: PMC9397473, DOI: 10.1080/15548627.2022.2025570.
• Comparative transcriptome analysis of hESC- and iPSC-derived lentoid bodiesAli M, Kabir F, Thomson JJ, Ma Y, Qiu C, Delannoy M, Khan SY, Riazuddin SA. Comparative transcriptome analysis of hESC- and iPSC-derived lentoid bodies. Scientific Reports 2019, 9: 18552. PMID: 31811247, PMCID: PMC6898283, DOI: 10.1038/s41598-019-54258-z.
• Critical role of Lin28‐TNFR2 signalling in cardiac stem cell activation and differentiationXiang Q, Yang B, Li L, Qiu B, Qiu C, Gao X, Zhou H, Min W. Critical role of Lin28‐TNFR2 signalling in cardiac stem cell activation and differentiation. Journal Of Cellular And Molecular Medicine 2019, 23: 0-0. PMID: 30734494, PMCID: PMC6433861, DOI: 10.1111/jcmm.14202.
• Generation and Proteome Profiling of PBMC-Originated, iPSC-Derived Corneal Endothelial CellsAli M, Khan SY, Vasanth S, Ahmed MR, Chen R, Na CH, Thomson JJ, Qiu C, Gottsch JD, Riazuddin SA. Generation and Proteome Profiling of PBMC-Originated, iPSC-Derived Corneal Endothelial Cells. Investigative Ophthalmology & Visual Science 2018, 59: 2437-2444. PMID: 29847650, PMCID: PMC5957521, DOI: 10.1167/iovs.17-22927.
• Tissue-Engineered Vascular Rings from Human iPSC-Derived Smooth Muscle CellsDash BC, Levi K, Schwan J, Luo J, Bartulos O, Wu H, Qiu C, Yi T, Ren Y, Campbell S, Rolle MW, Qyang Y. Tissue-Engineered Vascular Rings from Human iPSC-Derived Smooth Muscle Cells. Stem Cell Reports 2016, 7: 19-28. PMID: 27411102, PMCID: PMC4945325, DOI: 10.1016/j.stemcr.2016.05.004.
• Regulation of the DNA Methylation Landscape in Human Somatic Cell Reprogramming by the miR-29 FamilyHysolli E, Tanaka Y, Su J, Kim KY, Zhong T, Janknecht R, Zhou XL, Geng L, Qiu C, Pan X, Jung YW, Cheng J, Lu J, Zhong M, Weissman SM, Park IH. Regulation of the DNA Methylation Landscape in Human Somatic Cell Reprogramming by the miR-29 Family. Stem Cell Reports 2016, 7: 43-54. PMID: 27373925, PMCID: PMC4945581, DOI: 10.1016/j.stemcr.2016.05.014.
• Characterization of the mammalian miRNA turnover landscapeGuo Y, Liu J, Elfenbein SJ, Ma Y, Zhong M, Qiu C, Ding Y, Lu J. Characterization of the mammalian miRNA turnover landscape. Nucleic Acids Research 2015, 43: 2326-2341. PMID: 25653157, PMCID: PMC4344502, DOI: 10.1093/nar/gkv057.
• Small-Diameter Vascular Graft Engineered Using Human Embryonic Stem Cell-Derived Mesenchymal CellsSundaram S, Echter A, Sivarapatna A, Qiu C, Niklason L. Small-Diameter Vascular Graft Engineered Using Human Embryonic Stem Cell-Derived Mesenchymal Cells. Tissue Engineering Part A 2013, 20: 740-750. PMID: 24125588, PMCID: PMC3926168, DOI: 10.1089/ten.tea.2012.0738.
• Engineering a Blood-Retinal Barrier With Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium: Transcriptome and Functional AnalysisPeng S, Gan G, Qiu C, Zhong M, An H, Adelman RA, Rizzolo LJ. Engineering a Blood-Retinal Barrier With Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium: Transcriptome and Functional Analysis. Stem Cells Translational Medicine 2013, 2: 534-544. PMID: 23734062, PMCID: PMC3697821, DOI: 10.5966/sctm.2012-0134.
• Novel, high-yield red blood cell production methods from CD34-positive cells derived from human embryonic stem, yolk sac, fetal liver, cord blood, and peripheral blood.Olivier E, Qiu C, Bouhassira EE. Novel, high-yield red blood cell production methods from CD34-positive cells derived from human embryonic stem, yolk sac, fetal liver, cord blood, and peripheral blood. Stem Cells Translational Medicine 2012, 1: 604-14. PMID: 23197866, PMCID: PMC3659727, DOI: 10.5966/sctm.2012-0059.
• High‐Efficiency Transfection and siRNA‐Mediated Gene Knockdown in Human Pluripotent Stem CellsMa Y, Lin H, Qiu C. High‐Efficiency Transfection and siRNA‐Mediated Gene Knockdown in Human Pluripotent Stem Cells. Current Protocols In Stem Cell Biology 2012, 21: 5c.2.1-5c.2.9. PMID: 22605647, DOI: 10.1002/9780470151808.sc05c02s21.
• High-efficiency siRNA-based gene knockdown in human embryonic stem cellsMa Y, Jin J, Dong C, Cheng EC, Lin H, Huang Y, Qiu C. High-efficiency siRNA-based gene knockdown in human embryonic stem cells. RNA 2010, 16: 2564-2569. PMID: 20978109, PMCID: PMC2995416, DOI: 10.1261/rna.2350710.
• Dynamic transcriptomes during neural differentiation of human embryonic stem cells revealed by short, long, and paired-end sequencingWu JQ, Habegger L, Noisa P, Szekely A, Qiu C, Hutchison S, Raha D, Egholm M, Lin H, Weissman S, Cui W, Gerstein M, Snyder M. Dynamic transcriptomes during neural differentiation of human embryonic stem cells revealed by short, long, and paired-end sequencing. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 5254-5259. PMID: 20194744, PMCID: PMC2841935, DOI: 10.1073/pnas.0914114107.
• Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cellsQiu C, Ma Y, Wang J, Peng S, Huang Y. Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells. Nucleic Acids Research 2009, 38: 1240-1248. PMID: 19966271, PMCID: PMC2831306, DOI: 10.1093/nar/gkp1071.
• Complex developmental patterns of histone modifications associated with the human β-globin switch in primary cellsHsu M, Richardson CA, Olivier E, Qiu C, Bouhassira EE, Lowrey CH, Fiering S. Complex developmental patterns of histone modifications associated with the human β-globin switch in primary cells. Experimental Hematology 2009, 37: 799-806.e4. PMID: 19460472, PMCID: PMC2748252, DOI: 10.1016/j.exphem.2009.04.006.
• Developmentally regulated extended domains of DNA hypomethylation encompass highly transcribed genes of the human β-globin locusLathrop MJ, Hsu M, Richardson CA, Olivier EN, Qiu C, Bouhassira EE, Fiering S, Lowrey CH. Developmentally regulated extended domains of DNA hypomethylation encompass highly transcribed genes of the human β-globin locus. Experimental Hematology 2009, 37: 807-813.e2. PMID: 19460471, PMCID: PMC3792488, DOI: 10.1016/j.exphem.2009.04.005.
• Role for MKL1 in megakaryocytic maturationCheng EC, Luo Q, Bruscia EM, Renda MJ, Troy JA, Massaro SA, Tuck D, Schulz V, Mane SM, Berliner N, Sun Y, Morris SW, Qiu C, Krause DS. Role for MKL1 in megakaryocytic maturation. Blood 2009, 113: 2826-2834. PMID: 19136660, PMCID: PMC2661865, DOI: 10.1182/blood-2008-09-180596.
• Globin switches in yolk sac-like primitive and fetal-like definitive red blood cells produced from human embryonic stem cells.Qiu C, Olivier EN, Velho M, Bouhassira EE. Globin switches in yolk sac-like primitive and fetal-like definitive red blood cells produced from human embryonic stem cells. Blood 2008, 111: 2400-8. PMID: 18024790, PMCID: PMC2234066, DOI: 10.1182/blood-2007-07-102087.
• Large-scale production of embryonic red blood cells from human embryonic stem cells.Olivier EN, Qiu C, Velho M, Hirsch RE, Bouhassira EE. Large-scale production of embryonic red blood cells from human embryonic stem cells. Experimental Hematology 2006, 34: 1635-42. PMID: 17157159, DOI: 10.1016/j.exphem.2006.07.003.
• Differentiation of human embryonic stem cells into hematopoietic cells by coculture with human fetal liver cells recapitulates the globin switch that occurs early in development.Qiu C, Hanson E, Olivier E, Inada M, Kaufman DS, Gupta S, Bouhassira EE. Differentiation of human embryonic stem cells into hematopoietic cells by coculture with human fetal liver cells recapitulates the globin switch that occurs early in development. Experimental Hematology 2005, 33: 1450-8. PMID: 16338487, DOI: 10.1016/j.exphem.2005.09.003.