Yusheng Guo
Postdoctoral AssociateAbout
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Postdoctoral Associate
Biography
Yusheng Guo is currently a postdoctoral research associate in the Department of digestive disease, Yale school of medicine. He was a graduate research associate at the Ohio State University who earned his Ph.D. in December 2021 under the supervision of Dr. Anastasia Vlasova. Yusheng specializes in the field of virology and cell biology, and his specific research emphasis is on the evaluation of the role of cell surface glycans in rotavirus (RV) infection. He is currently working on the regulatory role of mitochondrial plays in the macrophage cells induced inflammation.
Research
Research at a Glance
Publications Timeline
A big-picture view of Yusheng Guo's research output by year.
6Publications
Publications
Featured Publications
Infection of porcine small intestinal enteroids with human and pig rotavirus A strains reveals contrasting roles for histo-blood group antigens and terminal sialic acids.
Guo Y, Candelero-Rueda RA, Saif LJ, Vlasova AN. Infection of porcine small intestinal enteroids with human and pig rotavirus A strains reveals contrasting roles for histo-blood group antigens and terminal sialic acids. PLoS Pathog 2021, 17: e1009237. PMID: 33513201, DOI: 10.1371/journal.ppat.1009237.Peer-Reviewed Original Research
2023
Host Cell Response to Rotavirus Infection with Emphasis on Virus-Glycan Interactions, Cholesterol Metabolism, and Innate Immunity.
Raque M, Raev SA, Guo Y, Kick MK, Saif LJ, Vlasova AN. Host Cell Response to Rotavirus Infection with Emphasis on Virus-Glycan Interactions, Cholesterol Metabolism, and Innate Immunity. Viruses 2023, 15 PMID: 37515094, DOI: 10.3390/v15071406.Peer-Reviewed Original ResearchGain-of-Function p53N236S Mutation Drives the Bypassing of HRas(V12)-Induced Cellular Senescence via PGC-1α.
Yang H, Zhang K, Guo Y, Guo X, Hou K, Hou J, Luo Y, Liu J, Jia S. Gain-of-Function p53N236S Mutation Drives the Bypassing of HRas(V12)-Induced Cellular Senescence via PGC-1α. Int J Mol Sci 2023, 24 PMID: 36835200, DOI: 10.3390/ijms24043790.Peer-Reviewed Original Research
2022
Rotavirus C Replication in Porcine Intestinal Enteroids Reveals Roles for Cellular Cholesterol and Sialic Acids.
Guo Y, Raev S, Kick MK, Raque M, Saif LJ, Vlasova AN. Rotavirus C Replication in Porcine Intestinal Enteroids Reveals Roles for Cellular Cholesterol and Sialic Acids. Viruses 2022, 14 PMID: 36016447, DOI: 10.3390/v14081825.Peer-Reviewed Original Research
2021
Rotavirus Interactions With Host Intestinal Epithelial Cells.
Amimo JO, Raev SA, Chepngeno J, Mainga AO, Guo Y, Saif L, Vlasova AN. Rotavirus Interactions With Host Intestinal Epithelial Cells. Front Immunol 2021, 12: 793841. PMID: 35003114, DOI: 10.3389/fimmu.2021.793841.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2020
Amino Acid Substitutions in Positions 385 and 393 of the Hydrophobic Region of VP4 May Be Associated with Rotavirus Attenuation and Cell Culture Adaptation.
Guo Y, Wentworth DE, Stucker KM, Halpin RA, Lam HC, Marthaler D, Saif LJ, Vlasova AN. Amino Acid Substitutions in Positions 385 and 393 of the Hydrophobic Region of VP4 May Be Associated with Rotavirus Attenuation and Cell Culture Adaptation. Viruses 2020, 12 PMID: 32272747, DOI: 10.3390/v12040408.Peer-Reviewed Original Research
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