2010
Shear stress-induced changes of membrane transporter localization and expression in mouse proximal tubule cells
Duan Y, Weinstein AM, Weinbaum S, Wang T. Shear stress-induced changes of membrane transporter localization and expression in mouse proximal tubule cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 21860-21865. PMID: 21106755, PMCID: PMC3003103, DOI: 10.1073/pnas.1015751107.Peer-Reviewed Original ResearchConceptsV-ATPaseFluid shear stressActin cytoskeletonNa/K-ATPaseIntact actin cytoskeletonApical plasma membraneK-ATPaseIntact microtubule networkShear stress-induced changesCellular functionsProximal tubule cellsApical NHE3Plasma membraneTransporter localizationMicrotubule networkIntracellular compartmentsWestern blot analysisCytochalasin DTubule cellsMPT cellsMicrotubule polymerizationTraffickingMouse proximal tubule cellsBlot analysisConfocal microscopy
2008
Shear-induced reorganization of renal proximal tubule cell actin cytoskeleton and apical junctional complexes
Duan Y, Gotoh N, Yan Q, Du Z, Weinstein AM, Wang T, Weinbaum S. Shear-induced reorganization of renal proximal tubule cell actin cytoskeleton and apical junctional complexes. Proceedings Of The National Academy Of Sciences Of The United States Of America 2008, 105: 11418-11423. PMID: 18685100, PMCID: PMC2516248, DOI: 10.1073/pnas.0804954105.Peer-Reviewed Original ResearchConceptsProximal tubule cells
2004
Mechanosensory function of microvilli of the kidney proximal tubule
Du Z, Duan Y, Yan Q, Weinstein AM, Weinbaum S, Wang T. Mechanosensory function of microvilli of the kidney proximal tubule. Proceedings Of The National Academy Of Sciences Of The United States Of America 2004, 101: 13068-13073. PMID: 15319475, PMCID: PMC516518, DOI: 10.1073/pnas.0405179101.Peer-Reviewed Original Research