2019
The bidirectional causal relationships of insomnia with five major psychiatric disorders: A Mendelian randomization study
Gao X, Meng L, Ma K, Liang J, Wang H, Gao Q, Wang T. The bidirectional causal relationships of insomnia with five major psychiatric disorders: A Mendelian randomization study. European Psychiatry 2019, 60: 79-85. PMID: 31234011, DOI: 10.1016/j.eurpsy.2019.05.004.Peer-Reviewed Original ResearchConceptsMajor psychiatric disordersPsychiatric disordersBipolar disorderAssociation of insomniaMendelian randomization studyAutism spectrum disorderOdds ratioObservational studySpectrum disorderInsomniaRandomization studyEffective interventionsCausal relationshipEgger regressionDisordersDisease modelsCausal roleMendelian randomizationConvincing evidenceGenome-wide association studiesAssociation
2017
Urinary bladder hypertrophy characteristic of male ROMK Bartter’s mice does not occur in female mice
Kim JM, Xu S, Guo X, Hu H, Dong K, Wang T. Urinary bladder hypertrophy characteristic of male ROMK Bartter’s mice does not occur in female mice. AJP Regulatory Integrative And Comparative Physiology 2017, 314: r334-r341. PMID: 29092859, PMCID: PMC5899254, DOI: 10.1152/ajpregu.00315.2017.Peer-Reviewed Original ResearchConceptsKO miceBladder hypertrophyBladder weightUrinary bladder hypertrophyRenal outer medullary potassium channelSeverity of hydronephrosisWild-type miceROMK knockout miceBladder capacityDetrusor muscleWT miceUrinary tractBartter's syndromeFemale miceSalt wastingHydronephrosisKnockout miceROMK expressionMiceBladderHypertrophyPotassium channelsMRNA levelsSignificant enlargementSyndrome