1997
Rabies virus infection of IMR-32 human neuroblastoma cells and effect of neurochemical and other agents
Lentz T, Fu Y, Lewis P. Rabies virus infection of IMR-32 human neuroblastoma cells and effect of neurochemical and other agents. Antiviral Research 1997, 35: 29-39. PMID: 9224959, DOI: 10.1016/s0166-3542(97)01036-x.Peer-Reviewed Original ResearchConceptsIMR-32 human neuroblastoma cellsIMR-32 cellsHuman neuroblastoma cellsNeuroblastoma cellsNeuronal nicotinic acetylcholine receptorsCentral nervous system receptorsRabies virusRabies virus infectionLysosomotropic agentsReceptor alpha1 subunitNicotinic acetylcholine receptorsNerve cell lineAttachment of virusNeurotropic virusesCholinergic agonistsViral antigensVirus infectionHuman neuronsAcetylcholine receptorsSynthetic peptidesCell bodiesInfectionAlpha1 subunitCholinergic ligandsBinding receptors
1996
Rabies virus binding to the nicotinic acetylcholine receptor α subunit demonstrated by virus overlay protein binding assay
Gastka M, Horvath J, Lentz T. Rabies virus binding to the nicotinic acetylcholine receptor α subunit demonstrated by virus overlay protein binding assay. Journal Of General Virology 1996, 77: 2437-2440. PMID: 8887475, DOI: 10.1099/0022-1317-77-10-2437.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBinding SitesBinding, CompetitiveBungarotoxinsElectric OrganRabies virusReceptors, NicotinicReceptors, VirusTorpedoConceptsAlpha subunitNicotinic acetylcholine receptor α subunitAcetylcholine receptor α subunitElectric organ membranesVirus overlay proteinVirus overlay protein binding assaysTransfer of proteinsReceptor α subunitProtein binding assaysAChR alpha subunitOverlay proteinRabies virusΑ-subunitSubunitsGel electrophoresisAcetylcholine receptorsBinding assaysCuraremimetic neurotoxinsProteinMembraneVirusBindingAChRBlot
1990
The recognition event between virus and host cell receptor: a target for antiviral agents
Lentz T. The recognition event between virus and host cell receptor: a target for antiviral agents. Journal Of General Virology 1990, 71: 751-766. PMID: 2109039, DOI: 10.1099/0022-1317-71-4-751.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAntiviral AgentsHumansMolecular Sequence DataReceptors, VirusViral ProteinsViruses
1988
Binding of viral attachment protein to host-cell receptor: the Achilles heel of infectious viruses
Lentz T. Binding of viral attachment protein to host-cell receptor: the Achilles heel of infectious viruses. Trends In Pharmacological Sciences 1988, 9: 247-252. PMID: 3073564, DOI: 10.1016/0165-6147(88)90154-x.Peer-Reviewed Original ResearchConceptsViral attachment proteinAttachment proteinHost cell receptorsVirus-receptor interactionsViral polypeptidesMolecular levelCellular receptorsProteinResult of bindingAchilles heelProduction of agentsStrain of virusSame receptorReceptorsVirus attachmentInfectious virusTherapeutic agentsVirusPolypeptideRational designSitesBinding
1983
The acetylcholine receptor as a cellular receptor for rabies virus.
Lentz T, Burrage T, Smith A, Tignor G. The acetylcholine receptor as a cellular receptor for rabies virus. The Yale Journal Of Biology And Medicine 1983, 56: 315-22. PMID: 6367238, PMCID: PMC2589619.Peer-Reviewed Original ResearchMeSH KeywordsAdhesivenessAnimalsHumansNervous SystemNeuromuscular JunctionRabiesRabies virusReceptors, CholinergicReceptors, VirusConceptsAcetylcholine receptorsHost cell receptorsRabies virusSpecific host cell receptorsCell receptorTissue tropismMotor nerve endingsRabies virus pathogenesisMyasthenia gravisAutoimmune diseasesCultured muscle cellsNerve endingsTranssynaptic transferViral antigensViral immunizationVirus pathogenesisDisease processNeurotransmitter receptorsViral infectionIntact hostCellular tropismNeuromuscular junctionInfected animalsMuscle cellsVirus attachment
1982
Is the Acetylcholine Receptor a Rabies Virus Receptor?
Lentz T, Burrage T, Smith A, Crick J, Tignor G. Is the Acetylcholine Receptor a Rabies Virus Receptor? Science 1982, 215: 182-184. PMID: 7053569, DOI: 10.1126/science.7053569.Peer-Reviewed Original Research