2000
Rabies virus entry at the neuromuscular junction in nerve–muscle cocultures
Lewis P, Fu Y, Lentz T. Rabies virus entry at the neuromuscular junction in nerve–muscle cocultures. Muscle & Nerve 2000, 23: 720-730. PMID: 10797395, DOI: 10.1002/(sici)1097-4598(200005)23:5<720::aid-mus9>3.0.co;2-5.Peer-Reviewed Original ResearchConceptsNerve cell bodiesRabies virus entryNerve-muscle coculturesNerve terminalsNerve fibersNeuromuscular junctionRabies virusCell bodiesVirus entryMotor nerve terminalsNerve-muscle contactsNicotinic acetylcholine receptorsVirus adsorption periodAcetylcholine receptorsLucifer YellowSynapsin ISynaptic vesiclesRetrograde transportVirusProgressive increaseEarly eventsCocultureSurface of cellsMyotube surfaceNeurons
1998
Rabies Virus Entry into Endosomes in IMR-32 Human Neuroblastoma Cells
Lewis P, Fu Y, Lentz T. Rabies Virus Entry into Endosomes in IMR-32 Human Neuroblastoma Cells. Experimental Neurology 1998, 153: 65-73. PMID: 9743568, DOI: 10.1006/exnr.1998.6879.Peer-Reviewed Original ResearchConceptsIMR-32 human neuroblastoma cellsRabies virus entryHuman neuroblastoma cellsRabies virusNeuroblastoma cellsNerve terminalsCell bodiesVirus entryIMR-32 neuroblastoma cellsSynaptic vesicle markersLucifer YellowCell surfaceSynapsin ITransferrin receptorVirusTexas Red dextranEarly eventsVesicle markersVirus particlesImmunofluorescence microscopyRabies virus entry into cultured rat hippo campalneurons
Lewis P, Lentz T. Rabies virus entry into cultured rat hippo campalneurons. Brain Cell Biology 1998, 27: 559-573. PMID: 10405023, DOI: 10.1023/a:1006912610044.Peer-Reviewed Original ResearchConceptsRabies virus entryCultured hippocampal neuronsViral antigensHippocampal neuronsRabies virusVirus entryRabies virus infectionSynaptic vesicle markersAxon terminalsNerve terminalsVirus infectionLysosomotropic agent chloroquineSomatodendritic domainCell bodiesVirus-containing endosomesLucifer YellowNeuronsSynapsin IInfectionAntigenTransferrin receptorVirusWheat germ agglutininAgent chloroquineVesicle markers
1988
Neurotoxin-Binding Site on The Acetylcholine Receptor
Lentz T, Wilson P. Neurotoxin-Binding Site on The Acetylcholine Receptor. International Review Of Neurobiology 1988, 29: 117-160. PMID: 3042662, DOI: 10.1016/s0074-7742(08)60085-9.Peer-Reviewed Original ResearchConceptsAcetylcholine-binding siteBinding of acetylcholineToxin-binding sitesPrimary amino acid sequenceAmino acid sequenceAcetylcholine receptorsCation-selective channelsAcid sequenceGenetic engineeringEssential functionsChemical signalsConformational changesNicotinic acetylcholine receptorsUse of toxinsMotor nerve terminalsMuscle cellsAChRCuraremimetic neurotoxinsBindingNeurotransmitter acetylcholineNeuromuscular junctionNicotinic AChRsReceptorsNerve terminalsHigh affinity
1977
Cytochemical localization of acetylcholine receptors at the neuromuscular junction by means of horseradish peroxidase-labelled α-bungarotoxin
Lentz T, Mazurkiewicz J, Rosenthal J. Cytochemical localization of acetylcholine receptors at the neuromuscular junction by means of horseradish peroxidase-labelled α-bungarotoxin. Brain Research 1977, 132: 423-442. PMID: 912399, DOI: 10.1016/0006-8993(77)90192-5.Peer-Reviewed Original ResearchConceptsMotor endplatesNerve terminalsACh receptorsJunctional foldsAcetylcholine receptorsNeuromuscular junctionPreincubation of tissuesIncubation of tissuePresynaptic activityAlpha-BTXHorseradish peroxidaseSynaptic cleftΑ-bungarotoxinNon-junctional regionsExtrajunctional regionsReceptorsMuscle fibersMuscle surfaceEndplateApical portionObvious accumulationTissueAxolemmaSlight activityCytochemical localization
1972
Effect of colchicine on the fine structure of the neuromuscular junction
Hsu L, Lentz T. Effect of colchicine on the fine structure of the neuromuscular junction. Cell And Tissue Research 1972, 135: 439-448. PMID: 4346118, DOI: 10.1007/bf00583428.Peer-Reviewed Original ResearchConceptsNeuromuscular junctionDrug-treated animalsInjection of colchicineMuscle surfaceNeurotrophic substancesEffect of colchicineNerve terminalsPostsynaptic foldsSynaptic vesiclesSpecialized morphological featuresNervePresent findingsColchicineDisappearance of microtubulesAdult newtsForearmConcomitant lossDISTRIBUTION OF LEUCINE-3H DURING AXOPLASMIC TRANSPORT WITHIN REGENERATING NEURONS AS DETERMINED BY ELECTRON-MICROSCOPE RADIOAUTOGRAPHY
Lentz T. DISTRIBUTION OF LEUCINE-3H DURING AXOPLASMIC TRANSPORT WITHIN REGENERATING NEURONS AS DETERMINED BY ELECTRON-MICROSCOPE RADIOAUTOGRAPHY. Journal Of Cell Biology 1972, 52: 719-732. PMID: 4109691, PMCID: PMC2108661, DOI: 10.1083/jcb.52.3.719.Peer-Reviewed Original ResearchConceptsNerve terminalsElectron microscope radioautographyDistribution of leucineLeucine-3HNerve endingsSensory gangliaRegenerating neuronsSpinal cordTrophic factorsAxoplasmic transportBrachial nervesPeripheral patternAxonal transportMyelinated nervesAxonsRelease of substancesRough-surfaced endoplasmic reticulumNerveInfusionGrowth conesNeuronsSilver grainsRadioautographyRadioautographic grains