Samantha Epstein, MD
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Neurology
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Assistant Professor
Biography
Dr. Epstein is an Assistant Professor in the Department of Neurology at Yale University. Dr. Epstein graduated summa cum laude from Dartmouth College, where she obtained a B.A. in Neuroscience. She received her doctorate degree from Harvard Medical School and completed her internal medicine internship and neurology residency at New York Presbyterian Hospital - Columbia University. After residency, she completed a two year clinical fellowship at Columbia University Irving Medical Center at the Columbia MS Center. Dr. Epstein is board certified in Neurology. She treats patients with multiple sclerosis and other inflammatory brain diseases and is involved in several clinical trials for these conditions.
Appointments
Neurology
Assistant ProfessorPrimary
Other Departments & Organizations
Education & Training
- Clinical Fellow in Multiple Sclerosis & Neuroimmunology
- Columbia University Irving Medical Center (2022)
- Resident Physician
- New York Presbyterian Hospital - Columbia University (2020)
- Intern
- New York Presbyterian Hospital - Columbia University (2017)
- MD
- Harvard Medical School (2016)
- BA
- Dartmouth College, Neuroscience (2011)
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Samantha Epstein's published research.
Publications Timeline
A big-picture view of Samantha Epstein's research output by year.
David Frumberg, MD, FAAOS
Erin Longbrake, MD/PhD
9Publications
29Citations
Publications
2022
Compassionate-use pocapavir and immunoglobulin therapy for treatment of rituximab-associated enterovirus meningoencephalitis.
Epstein S, Thakkar R, Fong KT, Ng J, Bearden DR, Mishra N, Thakur KT, Riley CS. Compassionate-use pocapavir and immunoglobulin therapy for treatment of rituximab-associated enterovirus meningoencephalitis. Journal Of Neurovirology 2022, 28: 329-334. PMID: 34981437, DOI: 10.1007/s13365-021-01038-z.Peer-Reviewed Original Research
2021
Vaccination Against SARS-CoV-2 in Neuroinflammatory Disease: Early Safety/Tolerability Data
Epstein S, Xia Z, Lee AJ, Dahl M, Edwards K, Levit E, Longbrake EE, Perrone C, Kavak K, Weinstock-Guttman B, Diallo F, Ricci A, Riley CS, De Jager PL, Farber R, Wesley SF, Collaborative M. Vaccination Against SARS-CoV-2 in Neuroinflammatory Disease: Early Safety/Tolerability Data. Multiple Sclerosis And Related Disorders 2021, 57: 103433. PMID: 34923427, PMCID: PMC8638239, DOI: 10.1016/j.msard.2021.103433.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsNeuromyelitis optica spectrum disorderSelf-reported side effectsNeuroinflammatory diseasesSARS-CoV-2Multiple sclerosisSide effectsSARS-CoV-2 vaccine trialsCross-sectional observational studySafety/tolerability dataAsymptomatic control populationNeurologist-confirmed diagnosisRadiologic disease activityRecurrent neurologic symptomsSignificant vaccine hesitancyOptica spectrum disorderAntibody-mediated diseasesVaccine side effectsViral vector vaccinesReal-world evidenceMultiple academic centersNID patientsUnvaccinated patientsVaccines surveyDisease activityNeurologic eventsMyelin oligodendrocyte glycoprotein (MOG) antibody-mediated disease: The difficulty of predicting relapses.
Epstein SE, Levin S, Onomichi K, Langston C, Yeshokumar A, Fabian M, Sand IK, Klineova S, Lublin F, Dykstra K, Xia Z, De Jager P, Levine L, Farber R, Riley C, Vargas WS. Myelin oligodendrocyte glycoprotein (MOG) antibody-mediated disease: The difficulty of predicting relapses. Multiple Sclerosis And Related Disorders 2021, 56: 103229. PMID: 34479112, DOI: 10.1016/j.msard.2021.103229.Peer-Reviewed Original ResearchNeurologic Safety Monitoring of COVID-19 Vaccines: Lessons From the Past to Inform the Present.
Thakur KT, Epstein S, Bilski A, Balbi A, Boehme AK, Brannagan TH, Wesley SF, Riley CS. Neurologic Safety Monitoring of COVID-19 Vaccines: Lessons From the Past to Inform the Present. Neurology 2021, 97: 767-775. PMID: 34475124, PMCID: PMC8548963, DOI: 10.1212/WNL.0000000000012703.Peer-Reviewed Original ResearchEvaluation of ocrelizumab in older progressive multiple sclerosis patients.
Epstein S, Fong KT, De Jager PL, Levine L, Riley C, Wesley S, Vargas WS, Farber R. Evaluation of ocrelizumab in older progressive multiple sclerosis patients. Multiple Sclerosis And Related Disorders 2021, 55: 103171. PMID: 34329872, DOI: 10.1016/j.msard.2021.103171.Peer-Reviewed Original ResearchCritical Analysis of a Challenging Case of Post-Infectious N-Methyl-D-Aspartate Receptor Encephalitis.
Epstein S, Ankam J, Vargas WS, Thakur KT. Critical Analysis of a Challenging Case of Post-Infectious N-Methyl-D-Aspartate Receptor Encephalitis. The Neurohospitalist 2021, 11: 160-164. PMID: 33791062, PMCID: PMC7958680, DOI: 10.1177/1941874420964356.Peer-Reviewed Original Research
2020
Inpatient Neurology Consultations During the Onset of the SARS-CoV-2 New York City Pandemic: A Single Center Case Series.
Radmard S, Epstein SE, Roeder HJ, Michalak AJ, Shapiro SD, Boehme A, Wilson TJ, Duran JC, Bain JM, Willey JZ, Thakur KT. Inpatient Neurology Consultations During the Onset of the SARS-CoV-2 New York City Pandemic: A Single Center Case Series. Frontiers In Neurology 2020, 11: 805. PMID: 32754113, PMCID: PMC7365853, DOI: 10.3389/fneur.2020.00805.Peer-Reviewed Original Research
2017
Near-peer teaching programme for medical students.
Gottlieb Z, Epstein S, Richards J. Near-peer teaching programme for medical students. The Clinical Teacher 2017, 14: 164-169. PMID: 27325161, DOI: 10.1111/tct.12540.Peer-Reviewed Original Research
2016
Prosthetic hip infection with Edwardsiella tarda in sickle cell beta thalassemia disease: A case report
Frumberg DB, Epstein SE, Jauregui JJ, Pivec R, Maheshwari AV. Prosthetic hip infection with Edwardsiella tarda in sickle cell beta thalassemia disease: A case report. Journal Of Clinical Orthopaedics And Trauma 2016, 7: 130-133. PMID: 28018092, PMCID: PMC5167442, DOI: 10.1016/j.jcot.2016.02.008.Peer-Reviewed Case Reports and Technical NotesCitationsConceptsTotal hip arthroplastyHip arthroplastyPeriprosthetic infectionNegative bacilliBilateral total hip arthroplastyPrimary total hip arthroplastyRevision total hip arthroplastyIntra-operative culturesStage IV osteonecrosisProsthetic hip infectionPeriprosthetic joint infectionSickle cell diseaseAntimicrobial resistance patternsLater-generation cephalosporinsAntibiotic spacerHip infectionMedical comorbiditiesDevastating complicationTibial osteomyelitisJoint infectionCase reportHip surgeryBeta-thalassemia diseaseCell diseasePrior history
Academic Achievements and Community Involvement
honor Rufus Choate Scholar
Regional AwardDartmouth CollegeDetails05/15/2022, 05/15/2009, 05/15/2008, 05/15/2007United Stateshonor Phi Beta Kappa
National AwardDetails09/15/2011United Stateshonor James O'Freedman Presidential Scholarship
Regional AwardDartmouth CollegeDetails09/15/2008United States
Clinical Care
Overview
Clinical Specialties
Neurology; Multiple Sclerosis
Fact Sheets
Multiple Sclerosis (MS)
Learn More on Yale MedicineAdvanced Imaging for Multiple Sclerosis
Learn More on Yale MedicineCarotid Artery Disease Imaging
Learn More on Yale MedicineStiff Person Syndrome (SPS)
Learn More on Yale Medicine
Board Certifications
Neurology
- Certification Organization
- AB of Psychiatry & Neurology
- Original Certification Date
- 2020
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