Qian Yu
Associate Research ScientistAbout
Research
Publications
2025
Secretory leukocyte protease inhibitor influences periarticular joint inflammation in Borrelia burgdorferi-infected mice
Yu Q, Tang X, Hart T, Homer R, Belperron A, Bockenstedt L, Ring A, Nakamura A, Fikrig E. Secretory leukocyte protease inhibitor influences periarticular joint inflammation in Borrelia burgdorferi-infected mice. ELife 2025, 14: rp104913. PMID: 40392222, PMCID: PMC12092001, DOI: 10.7554/elife.104913.Peer-Reviewed Original ResearchSecretory leukocyte protease inhibitor influences periarticular joint inflammation in Borrelia burgdorferi-infected mice
Yu Q, Tang X, Hart T, Homer R, Belperron A, Bockenstedt L, Ring A, Nakamura A, Fikrig E. Secretory leukocyte protease inhibitor influences periarticular joint inflammation in Borrelia burgdorferi-infected mice. ELife 2025, 14 DOI: 10.7554/elife.104913.4.Peer-Reviewed Original ResearchCCL17 Influences Borrelia burgdorferi Infection in the Heart
Tang X, Yu Q, Cui Y, Hart T, Rivas-Giorgi F, Calloway K, Mohapatra A, Fikrig E. CCL17 Influences Borrelia burgdorferi Infection in the Heart. Journal Of Infectious Diseases 2025, 232: 162-169. PMID: 39777514, PMCID: PMC12308671, DOI: 10.1093/infdis/jiaf011.Peer-Reviewed Original Research
2024
Neisseria gonorrhoeae induces local secretion of IL-10 at the human cervix to promote colonization
Dai Y, Edwards V, Yu Q, Tettelin H, Stein D, Song W. Neisseria gonorrhoeae induces local secretion of IL-10 at the human cervix to promote colonization. Journal Of Clinical Investigation 2024, 135: e183331. PMID: 39585777, PMCID: PMC11735093, DOI: 10.1172/jci183331.Peer-Reviewed Original Research
2021
Gonococcal invasion into epithelial cells depends on both cell polarity and ezrin
Yu Q, Wang L, Di Benigno S, Stein D, Song W. Gonococcal invasion into epithelial cells depends on both cell polarity and ezrin. PLOS Pathogens 2021, 17: e1009592. PMID: 34852011, PMCID: PMC8668114, DOI: 10.1371/journal.ppat.1009592.Peer-Reviewed Original Research
2020
Adaptation of Neisseria gonorrhoeae to the Female Reproductive Tract
Song W, Yu Q, Wang L, Stein D. Adaptation of Neisseria gonorrhoeae to the Female Reproductive Tract. Microbiology Insights 2020, 13: 1178636120947077. PMID: 32848409, PMCID: PMC7425258, DOI: 10.1177/1178636120947077.Peer-Reviewed Original Research
2019
Neisseria gonorrhoeae infects the heterogeneous epithelia of the human cervix using distinct mechanisms
Yu Q, Wang L, Di Benigno S, Gray-Owen S, Stein D, Song W. Neisseria gonorrhoeae infects the heterogeneous epithelia of the human cervix using distinct mechanisms. PLOS Pathogens 2019, 15: e1008136. PMID: 31790511, PMCID: PMC6907876, DOI: 10.1371/journal.ppat.1008136.Peer-Reviewed Original Research
2018
Immunofluorescence Analysis of Human Endocervical Tissue Explants Infected with Neisseria gonorrhoeae
Wang L, Yu Q, Stein D, Song W. Immunofluorescence Analysis of Human Endocervical Tissue Explants Infected with Neisseria gonorrhoeae. Bio-protocol 2018, 8: e2720. PMID: 29780854, PMCID: PMC5959038, DOI: 10.21769/bioprotoc.2720.Peer-Reviewed Original Research
2017
Neisseria gonorrhoeae infects the human endocervix by activating non-muscle myosin II-mediated epithelial exfoliation
Wang L, Yu Q, Edwards V, Lin B, Qiu J, Turner J, Stein D, Song W. Neisseria gonorrhoeae infects the human endocervix by activating non-muscle myosin II-mediated epithelial exfoliation. PLOS Pathogens 2017, 13: e1006269. PMID: 28406994, PMCID: PMC5391109, DOI: 10.1371/journal.ppat.1006269.Peer-Reviewed Original Research
2014
Structural insights into the T6SS effector protein Tse3 and the Tse3–Tsi3 complex from Pseudomonas aeruginosa reveal a calcium‐dependent membrane‐binding mechanism
Lu D, Shang G, Zhang H, Yu Q, Cong X, Yuan J, He F, Zhu C, Zhao Y, Yin K, Chen Y, Hu J, Zhang X, Yuan Z, Xu S, Hu W, Cang H, Gu L. Structural insights into the T6SS effector protein Tse3 and the Tse3–Tsi3 complex from Pseudomonas aeruginosa reveal a calcium‐dependent membrane‐binding mechanism. Molecular Microbiology 2014, 92: 1092-1112. PMID: 24724564, DOI: 10.1111/mmi.12616.Peer-Reviewed Original Research
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