Jing Wu
Associate Research Scientist in Pharmacology
Biography
Research & Publications
Selected Publications
- Disease-causing Slack potassium channel mutations produce opposite effects on excitability of excitatory and inhibitory neuronsWu J, Quraishi I, Zhang Y, Bromwich M, Kaczmarek L. Disease-causing Slack potassium channel mutations produce opposite effects on excitability of excitatory and inhibitory neurons. Cell Reports 2024, 43: 113904. PMID: 38457342, PMCID: PMC11013952, DOI: 10.1016/j.celrep.2024.113904.
- Interaction Between HCN and Slack Channels Regulates mPFC Pyramidal Cell Excitability in Working Memory CircuitsWu J, El-Hassar L, Datta D, Thomas M, Zhang Y, Jenkins D, DeLuca N, Chatterjee M, Gribkoff V, Arnsten A, Kaczmarek L. Interaction Between HCN and Slack Channels Regulates mPFC Pyramidal Cell Excitability in Working Memory Circuits. Molecular Neurobiology 2023, 61: 2430-2445. PMID: 37889366, DOI: 10.1007/s12035-023-03719-8.
- Editorial: Role of pyroptosis in neurological disorders and its therapeutic approachesWu J, Mnatsakanyan N, Ji M. Editorial: Role of pyroptosis in neurological disorders and its therapeutic approaches. Frontiers In Aging Neuroscience 2023, 15: 1253644. PMID: 37559678, PMCID: PMC10407944, DOI: 10.3389/fnagi.2023.1253644.
- Mitochondrial ATP synthase F1 subcomplex forms a gate of c-subunit leak channelMnatsakanyan N, Park H, Wu J, Jonas E. Mitochondrial ATP synthase F1 subcomplex forms a gate of c-subunit leak channel. Biochimica Et Biophysica Acta (BBA) - Bioenergetics 2022, 1863: 148774. DOI: 10.1016/j.bbabio.2022.148774.
- Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F1 subcomplexMnatsakanyan N, Park HA, Wu J, He X, Llaguno MC, Latta M, Miranda P, Murtishi B, Graham M, Weber J, Levy RJ, Pavlov EV, Jonas EA. Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F1 subcomplex. Cell Death & Differentiation 2022, 29: 1874-1887. PMID: 35322203, PMCID: PMC9433415, DOI: 10.1038/s41418-022-00972-7.
- Modulation of Neuronal Potassium Channels During Auditory ProcessingWu J, Kaczmarek LK. Modulation of Neuronal Potassium Channels During Auditory Processing. Frontiers In Neuroscience 2021, 15: 596478. PMID: 33613177, PMCID: PMC7887315, DOI: 10.3389/fnins.2021.596478.
- The role of ATP synthase megachannel in mitochondrial permeability transitionMnatsakanyan N, Park H, Wu J, Miranda P, Jonas E. The role of ATP synthase megachannel in mitochondrial permeability transition. Biochimica Et Biophysica Acta (BBA) - Bioenergetics 2018, 1859: e112. DOI: 10.1016/j.bbabio.2018.09.330.
- Molecular Composition, Structure and Regulation of the Mitochondrial Permeability Transition PoreMnatsakanyan N, Park H, Wu J, Miranda P, Jonas E. Molecular Composition, Structure and Regulation of the Mitochondrial Permeability Transition Pore. Biophysical Journal 2018, 114: 658a. DOI: 10.1016/j.bpj.2017.11.3555.
- New Insights into the Molecular Structure and Regulation of the Mitochondrial Permeability Transition PoreMnatsakanyan N, Park H, Wu J, Miranda P, Jonas E. New Insights into the Molecular Structure and Regulation of the Mitochondrial Permeability Transition Pore. Biophysical Journal 2017, 112: 440a. DOI: 10.1016/j.bpj.2016.11.2349.
- PTP and LTP: The physiological role of the permeability transition pore in learning and memoryJonas E, Miranda P, Gribkoff V, Alavian K, Park H, Wu J, Chavez A, Zukin R, Hardwick J, Mnatsakanyan N. PTP and LTP: The physiological role of the permeability transition pore in learning and memory. Biochimica Et Biophysica Acta (BBA) - Bioenergetics 2016, 1857: e66-e67. DOI: 10.1016/j.bbabio.2016.04.357.
- The role of ATP synthase in mitochondrial permeability transition, neuronal death and survivalMnatsakanyan N, Park H, Wu J, Miranda P, Jonas E. The role of ATP synthase in mitochondrial permeability transition, neuronal death and survival. Biochimica Et Biophysica Acta (BBA) - Bioenergetics 2016, 1857: e68. DOI: 10.1016/j.bbabio.2016.04.362.
- A Novel Ion Channel in ATP Synthase C-Subunit Ring: Gatekeeper of Life and DeathMnatsakanyan N, Park H, Wu J, Miranda P, Jonas E. A Novel Ion Channel in ATP Synthase C-Subunit Ring: Gatekeeper of Life and Death. Biophysical Journal 2016, 110: 310a. DOI: 10.1016/j.bpj.2015.11.1664.