Jessica Furtado
Postdoctoral AssociateAbout
Research
Publications
2026
Polycomb Repressive Complex 2 drives flow-sensitive endothelial states underlying vascular inflammation and disease
Joshi D, Rukhlenko O, Tuliakova A, Sun Z, Bhogale T, Furtado J, Traylor J, Imoto H, Orr A, Tellides G, Martin K, Kholodenko B, Schwartz M. Polycomb Repressive Complex 2 drives flow-sensitive endothelial states underlying vascular inflammation and disease. Proceedings Of The National Academy Of Sciences Of The United States Of America 2026, 123: e2603888123. PMID: 42673460, PMCID: PMC13552879, DOI: 10.1073/pnas.2603888123.Peer-Reviewed Original ResearchWhen lactate speaks: Rewiring astrocyte-neuron metabolism in Alzheimer’s disease
Furtado J, Schneeberger M. When lactate speaks: Rewiring astrocyte-neuron metabolism in Alzheimer’s disease. Cell Metabolism 2026, 38: 1527-1528. PMID: 42551412, DOI: 10.1016/j.cmet.2026.05.007.Peer-Reviewed Original ResearchIdentification of a thermogenic target in the dorsal raphe nucleus for weight management in mice
Moura-Assis A, Plucińska K, Meseguer D, Baleisyte A, Chen B, Pellegrino K, Parolari L, Shaked J, Page K, Barrows D, Carroll T, Grajales-Reyes J, Na D, Rodriguez-Diaz A, Furtado J, Isaza J, Schiffer H, Chen Y, Sun H, Kaushal N, Monenschein H, Barker D, Ortuño M, Renier N, Cohen P, Carlton M, Heintz N, Brice N, Friedman J, Schneeberger M. Identification of a thermogenic target in the dorsal raphe nucleus for weight management in mice. Nature Communications 2026, 17: 1295. PMID: 41530127, PMCID: PMC12868712, DOI: 10.1038/s41467-025-68056-x.Peer-Reviewed Original Research
2025
Endothelial Rho kinase controls blood vessel integrity and angiogenesis
Francis C, Furtado J, Granger J, Kim Y, Liao J, Akar F, Eichmann A. Endothelial Rho kinase controls blood vessel integrity and angiogenesis. Cardiovascular Research 2025, 121: 2968-2982. PMID: 41403023, DOI: 10.1093/cvr/cvaf246.Peer-Reviewed Original ResearchRestoring compromised blood-retina-barrier integrity with Netrin-1 overexpression
Furtado J, Zapadka T, Park H, Boyé K, Demb J, Eichmann A. Restoring compromised blood-retina-barrier integrity with Netrin-1 overexpression. Cellular And Molecular Life Sciences 2025, 82: 389. PMID: 41196411, PMCID: PMC12592616, DOI: 10.1007/s00018-025-05903-6.Peer-Reviewed Original ResearchPIEZO1 Overexpression in Hereditary Hemorrhagic Telangiectasia Arteriovenous Malformations
Park H, Furtado J, Robinson M, Antaya R, Oh S, Hong Y, Schwartz M, Young L, Eichmann A. PIEZO1 Overexpression in Hereditary Hemorrhagic Telangiectasia Arteriovenous Malformations. Circulation 2025, 152: 599-615. PMID: 40665909, PMCID: PMC12270330, DOI: 10.1161/circulationaha.124.073630.Peer-Reviewed Original ResearchNeurovascular plasticity as a modulator of hypothalamic function
Chen B, Furtado J, Schneeberger M. Neurovascular plasticity as a modulator of hypothalamic function. Reviews In Endocrine And Metabolic Disorders 2025, 27: 493-503. PMID: 40542999, DOI: 10.1007/s11154-025-09982-5.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2024
Interplay between Netrin-1 and Norrin controls arteriovenous zonation of blood–retina barrier integrity
Furtado J, Geraldo L, Leser F, Bartkowiak B, Poulet M, Park H, Robinson M, Pibouin-Fragner L, Eichmann A, Boyé K. Interplay between Netrin-1 and Norrin controls arteriovenous zonation of blood–retina barrier integrity. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2408674121. PMID: 39693351, PMCID: PMC11670198, DOI: 10.1073/pnas.2408674121.Peer-Reviewed Original ResearchMonoclonal antibodies that block Roundabout 1 and 2 signaling target pathological ocular neovascularization through myeloid cells
Geraldo L, Xu Y, Mouthon G, Furtado J, Leser F, Blazer L, Adams J, Zhang S, Zheng L, Song E, Robinson M, Thomas J, Sidhu S, Eichmann A. Monoclonal antibodies that block Roundabout 1 and 2 signaling target pathological ocular neovascularization through myeloid cells. Science Translational Medicine 2024, 16: eadn8388-eadn8388. PMID: 39565875, PMCID: PMC11822886, DOI: 10.1126/scitranslmed.adn8388.Peer-Reviewed Original ResearchVascular development, remodeling and maturation
Furtado J, Eichmann A. Vascular development, remodeling and maturation. Current Topics In Developmental Biology 2024, 159: 344-370. PMID: 38729681, DOI: 10.1016/bs.ctdb.2024.02.001.Chapters