James S. Farrelly, MD, MHS
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Assistant Professor of Surgery (General, Trauma & Surgical Critical Care)
Appointments
General Surgery, Trauma & Surgical Critical Care
Assistant ProfessorPrimary
Other Departments & Organizations
Education & Training
- Surgical Critical Care Fellow
- Yale New Haven Hospital/Yale School of Medicine (2021)
- Resident Physician
- Yale New Haven Hospital/Yale School of Medicine (2020)
- MHS
- Yale University Graduate School of Arts and Sciences (2017)
- Pediatric Surgery Research Fellow
- Yale School of Medicine (2017)
- MD
- State University of New York Downstate Med Ctr., Clinical Neuroscience Pathway, cum laude (2013)
- BA
- Davidson College, Music Major, Chemistry Minor, cum laude (2008)
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of James S. Farrelly's published research.
Publications Timeline
A big-picture view of James S. Farrelly's research output by year.
David Stitelman, MD
Francesc Lopez-Giraldez, PhD
Michael Caty, MD, MMM
Peter M. Glazer, MD, PhD
Suleyman Coskun, PhD, MSc
6Publications
238Citations
Publications
2018
Alginate microparticles loaded with basic fibroblast growth factor induce tissue coverage in a rat model of myelomeningocele
Farrelly JS, Bianchi AH, Ricciardi AS, Buzzelli GL, Ahle SL, Freedman-Weiss MR, Luks VL, Saltzman WM, Stitelman DH. Alginate microparticles loaded with basic fibroblast growth factor induce tissue coverage in a rat model of myelomeningocele. Journal Of Pediatric Surgery 2018, 54: 80-85. PMID: 30414695, DOI: 10.1016/j.jpedsurg.2018.10.031.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSoft tissue coverageTissue coverageRat modelTime-dated pregnant ratsFree bFGFGrowth factorInjection of microparticlesBasic fibroblast growth factorFibroblast growth factorPregnant ratsPrenatal treatmentIntraamniotic injectionFetal myelomeningoceleMyelomeningoceleMMC coverageMMC defectsRetinoic acidBFGFIn utero nanoparticle delivery for site-specific genome editing
Ricciardi AS, Bahal R, Farrelly JS, Quijano E, Bianchi AH, Luks VL, Putman R, López-Giráldez F, Coşkun S, Song E, Liu Y, Hsieh WC, Ly DH, Stitelman DH, Glazer PM, Saltzman WM. In utero nanoparticle delivery for site-specific genome editing. Nature Communications 2018, 9: 2481. PMID: 29946143, PMCID: PMC6018676, DOI: 10.1038/s41467-018-04894-2.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSite-specific genome editingReversal of splenomegalyPeptide nucleic acidIntra-amniotic administrationBlood hemoglobin levelsMonogenic disordersNanoparticle deliveryPolymeric nanoparticlesPostnatal elevationGestational ageHemoglobin levelsImproved survivalPediatric morbidityDisease improvementHuman β-thalassemiaReticulocyte countNormal organ developmentMouse modelNormal rangeEarly interventionGenome editingOff-target mutationsPostnatal growthGene editingVersatile method
2017
Surgical tray optimization as a simple means to decrease perioperative costs
Farrelly JS, Clemons C, Witkins S, Hall W, Christison-Lagay ER, Ozgediz DE, Cowles RA, Stitelman DH, Caty MG. Surgical tray optimization as a simple means to decrease perioperative costs. Journal Of Surgical Research 2017, 220: 320-326. PMID: 29180198, DOI: 10.1016/j.jss.2017.06.029.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSurgery sectionSingle-site observational studyHealth care cost reductionLarge academic medical centerHospital cost reductionCare cost reductionAcademic medical centerSurgical tray optimizationSurgical traysStudy startHealth care spendingSpine surgeryObservational studySurgical sectionMedical CenterPediatric surgeryPediatric surgeonsPerioperative costsAcademic centersUrology SectionOperating room nursingMultidisciplinary teamPediatric urologyPediatric orthopedicsScrub technicians
2016
Complications in pediatric enteral and vascular access
Farrelly JS, Stitelman DH. Complications in pediatric enteral and vascular access. Seminars In Pediatric Surgery 2016, 25: 371-379. PMID: 27989361, DOI: 10.1053/j.sempedsurg.2016.10.006.Peer-Reviewed Original ResearchCitationsMeSH Keywords and Concepts- Farrelly JS, Cleary MA, Weiss RM, Morotti R, Stitelman DH. Acquired seminal vesicle cyst in a teenager with a urethral stricture of unknown etiology. Journal of Pediatric Surgery Case Reports. Volume 7, Pages 1-50 (April 2016)Peer-Reviewed Original Research
2012
A phase I/IIA study of AGS-PSCA for castration-resistant prostate cancer.
Morris MJ, Eisenberger MA, Pili R, Denmeade SR, Rathkopf D, Slovin SF, Farrelly J, Chudow JJ, Vincent M, Scher HI, Carducci MA. A phase I/IIA study of AGS-PSCA for castration-resistant prostate cancer. Annals Of Oncology : Official Journal Of The European Society For Medical Oncology / ESMO 2012, 23: 2714-9. PMID: 22553195, PMCID: PMC3457748, DOI: 10.1093/annonc/mds078.Peer-Reviewed Original Research
Clinical Care
Overview
Clinical Specialties
General Surgery, Trauma & Surgical Critical Care
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