Haowei Wang
Neuroinflammation Senior TechnicianCards
About
Research
Publications
2021
The Type II Anti‐CD20 Antibody Obinutuzumab (GA101) Is More Effective Than Rituximab at Depleting B Cells and Treating Disease in a Murine Lupus Model
Marinov A, Wang H, Bastacky S, van Puijenbroek E, Schindler T, Speziale D, Perro M, Klein C, Nickerson K, Shlomchik M. The Type II Anti‐CD20 Antibody Obinutuzumab (GA101) Is More Effective Than Rituximab at Depleting B Cells and Treating Disease in a Murine Lupus Model. Arthritis & Rheumatology 2021, 73: 826-836. PMID: 33277983, PMCID: PMC8084886, DOI: 10.1002/art.41608.Peer-Reviewed Original Research
2016
PTPN22 inhibition resets defective human central B cell tolerance
Schickel JN, Kuhny M, Baldo A, Bannock JM, Massad C, Wang H, Katz N, Oe T, Menard L, Soulas-Sprauel P, Strowig T, Flavell R, Meffre E. PTPN22 inhibition resets defective human central B cell tolerance. Science Immunology 2016, 1: aaf7153. PMID: 27917411, PMCID: PMC5127630, DOI: 10.1126/sciimmunol.aaf7153.Peer-Reviewed Original Research
2014
Activation of Rheumatoid Factor–Specific B Cells Is Antigen Dependent and Occurs Preferentially Outside of Germinal Centers in the Lupus-Prone NZM2410 Mouse Model
Sang A, Niu H, Cullen J, Choi SC, Zheng YY, Wang H, Shlomchik MJ, Morel L. Activation of Rheumatoid Factor–Specific B Cells Is Antigen Dependent and Occurs Preferentially Outside of Germinal Centers in the Lupus-Prone NZM2410 Mouse Model. The Journal Of Immunology 2014, 193: 1609-1621. PMID: 25015835, PMCID: PMC4119566, DOI: 10.4049/jimmunol.1303000.Peer-Reviewed Original ResearchAnimalsAutoantibodiesAutoantigensB-LymphocytesCell DifferentiationCells, CulturedChromatinDisease Models, AnimalFemaleGerminal CenterImmune ToleranceImmunoglobulin GLupus Erythematosus, SystemicLymphocyte ActivationMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutReceptors, Antigen, B-CellRheumatoid FactorToll-Like Receptor 7Toll-Like Receptor 9
1999
Regulation of autoreactive anti-IgG (Rheumatoid Factor) B cells in normal and autoimmune mice
Wang H, Shlomchik M. Regulation of autoreactive anti-IgG (Rheumatoid Factor) B cells in normal and autoimmune mice. Immunologic Research 1999, 19: 259-270. PMID: 10493179, DOI: 10.1007/bf02786493.Peer-Reviewed Original Research
1998
Maternal Ig mediates neonatal tolerance in rheumatoid factor transgenic mice but tolerance breaks down in adult mice.
Wang H, Shlomchik M. Maternal Ig mediates neonatal tolerance in rheumatoid factor transgenic mice but tolerance breaks down in adult mice. The Journal Of Immunology 1998, 160: 2263-71. PMID: 9498766, DOI: 10.4049/jimmunol.160.5.2263.Peer-Reviewed Original Research
1997
High affinity rheumatoid factor transgenic B cells are eliminated in normal mice.
Wang H, Shlomchik M. High affinity rheumatoid factor transgenic B cells are eliminated in normal mice. The Journal Of Immunology 1997, 159: 1125-34. PMID: 9233605, DOI: 10.4049/jimmunol.159.3.1125.Peer-Reviewed Original Research
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