Gary Hunnicutt, PhD
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Cards
Appointments
Medical Oncology
Primary
Titles
Assistant Director, Research Affairs, Yale Cancer Center
Contact Info
Yale School of Medicine
Fitkin Memorial Pavilion, 789 Howard Ave
New Haven, CT 06519
United States
Appointments
Medical Oncology
Primary
Titles
Assistant Director, Research Affairs, Yale Cancer Center
Contact Info
Yale School of Medicine
Fitkin Memorial Pavilion, 789 Howard Ave
New Haven, CT 06519
United States
Appointments
Medical Oncology
Primary
Titles
Assistant Director, Research Affairs, Yale Cancer Center
Contact Info
Yale School of Medicine
Fitkin Memorial Pavilion, 789 Howard Ave
New Haven, CT 06519
United States
About
Titles
Research Scientist
Assistant Director, Research Affairs, Yale Cancer CenterBiography
Dr. Hunnicutt received his PhD from the University of Texas Southwestern Medical Center before becoming a postdoctoral fellow at the UCONN medical center in Farmington. He then was a senior scientist for the Population Council at the Rockefeller University campus for 14 years before joining the National Institutes of Health, where he spent a decade with the Center for Scientific Review. In 2020 he joined the Yale as a Research Scientist for the Department of Medicine and as the Assistant Director of Research Affairs for the Yale Cancer Center.
Appointments
Medical Oncology
Research ScientistPrimary
Other Departments & Organizations
Education & Training
- PhD
- University of Texas Southwestern Medical Center (1989)
Research
Research at a Glance
Publications Timeline
A big-picture view of Gary Hunnicutt's research output by year.
14Publications
784Citations
Publications
2012
Trainee Forum—Writing Winning Grants.
Taymans S, Moss S, Hunnicutt G. Trainee Forum—Writing Winning Grants. Biology Of Reproduction 2012, 87: 1-1. DOI: 10.1093/biolreprod/87.s1.1.Peer-Reviewed Original ResearchCitations
2007
DIRECT EVIDENCE THAT THE SPERM ANNULUS IS REQUIRED FOR MEMBRANE DOMAIN MAINTENANCE AND NORMAL SPERM MATURATION
Hunnicutt G, Fernandez M, Steller H, Kwitny S. DIRECT EVIDENCE THAT THE SPERM ANNULUS IS REQUIRED FOR MEMBRANE DOMAIN MAINTENANCE AND NORMAL SPERM MATURATION. Biology Of Reproduction 2007, 77: 115-115. DOI: 10.1093/biolreprod/77.s1.115.Peer-Reviewed Original ResearchGM1 DYNAMICS INDICATE MEMBRANE CHANGES ASSOCIATED WITH CAPACITATION IN MURINE SPERMATOZOA
Selvaraj V, Buttke D, Atsushi A, Nelson J, Klaus A, Hunnicutt G, Travis A. GM1 DYNAMICS INDICATE MEMBRANE CHANGES ASSOCIATED WITH CAPACITATION IN MURINE SPERMATOZOA. Biology Of Reproduction 2007, 77: 166-166. DOI: 10.1093/biolreprod/77.s1.166.Peer-Reviewed Original ResearchCitationsAltmetricConceptsPost-acrosomal plasma membranePlasma membraneAcrosomal exocytosisSterol effluxProgesterone-induced acrosomal exocytosisMurine spermatozoaMembrane changesMurine spermDramatic redistributionLive cellsBovine sperm headSperm deathSubunit BExocytosisStimulus-specific changesMale fertilitySperm headCapacitationSperm responseStimulus-specific patternsCholera toxin subunit BMembraneGanglioside GM1Sperm populationSpecific stimuli171 Creation of a SCCRO (DCN-1) knockout mouse results in decreased CUL3 neddylation and male infertility
Kaufman A, Kim A, Ryan R, Huryn L, Conway A, Manova K, Morris P, Hunnicutt G, Ramanathan Y, Singh B. 171 Creation of a SCCRO (DCN-1) knockout mouse results in decreased CUL3 neddylation and male infertility. Journal Of Surgical Research 2007, 137: 224. DOI: 10.1016/j.jss.2006.12.186.Peer-Reviewed Original ResearchCitations
2006
Ultrastructural Features of Mammalian Sperm: Applications of Cold Field-Emission Scanning Electron Microscopy
Klaus A, Hunnicutt G. Ultrastructural Features of Mammalian Sperm: Applications of Cold Field-Emission Scanning Electron Microscopy. Microscopy And Microanalysis 2006, 12: 232-233. DOI: 10.1017/s1431927606067614.Peer-Reviewed Original Research
2005
Immune Complex Deposition in Adult Male Sprague–Dawley Rats Chronically Immunized with GnRH
Vargas L, Sewell R, Marshall A, Galatioto J, Tsong Y, Catterall J, Hunnicutt G. Immune Complex Deposition in Adult Male Sprague–Dawley Rats Chronically Immunized with GnRH. American Journal Of Reproductive Immunology 2005, 54: 292-310. PMID: 16212651, DOI: 10.1111/j.1600-0897.2005.00310.x.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsImmune complex depositionImmune complexesComplex depositionChronic immunizationAdult male Sprague-Dawley ratsMale Sprague-Dawley ratsAnti-GnRH antibodiesGlomerular immune complexesPotential deleterious side effectsSprague-Dawley ratsDeleterious side effectsIC depositionPathologic effectsSide effectsEffective immunocontraceptiveImmunizationFinal analysisOrgan analysisCellular damageRatsMost tissuesImmunofluorescence microscopyCellular levelAnimalsGnRHThe Sept4 Septin Locus Is Required for Sperm Terminal Differentiation in Mice
Kissel H, Georgescu M, Larisch S, Manova K, Hunnicutt G, Steller H. The Sept4 Septin Locus Is Required for Sperm Terminal Differentiation in Mice. Developmental Cell 2005, 8: 353-364. PMID: 15737931, DOI: 10.1016/j.devcel.2005.01.021.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCaspase inhibitor XIAPDiverse cellular functionsDifferent cellular compartmentsInhibition of XIAPGenomic lociMutant spermCellular functionsMouse developmentMitochondrial architectureCellular compartmentsTumor suppressionTerminal differentiationSperm maturationDefective spermRing-like structureTargeted deletionResidual cytoplasmProteinMutant miceXIAPLociTail regionCytoplasmSpermCytokinesis
2001
Expression and Localization of Caveolin-1, and the Presence of Membrane Rafts, in Mouse and Guinea Pig Spermatozoa
Travis A, Merdiushev T, Vargas L, Jones B, Purdon M, Nipper R, Galatioto J, Moss S, Hunnicutt G, Kopf G. Expression and Localization of Caveolin-1, and the Presence of Membrane Rafts, in Mouse and Guinea Pig Spermatozoa. Developmental Biology 2001, 240: 599-610. PMID: 11784086, DOI: 10.1006/dbio.2001.0475.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMouse male germ cellsMale germ cellsCaveolin-1Membrane raftsDetergent-insoluble lipid raftsGerm cellsSimilar cellular functionsTrafficking of cholesterolImmunofluorescence analysisConfocal immunofluorescence analysisLight buoyant densityMembrane subdomainsGuinea pig spermatozoaSyntaxin 2Cellular functionsSucrose density gradient centrifugationFlagellar motilityLipid raftsIndirect immunofluorescence analysisNonraft fractionsSomatic cellsMembrane dynamicsAcrosomal biogenesisPig spermatozoaMature spermGuinea Pig Fertilin Exhibits Restricted Lateral Mobility in Epididymal Sperm and Becomes Freely Diffusing during Capacitation
Cowan A, Koppel D, Vargas L, Hunnicutt G. Guinea Pig Fertilin Exhibits Restricted Lateral Mobility in Epididymal Sperm and Becomes Freely Diffusing during Capacitation. Developmental Biology 2001, 236: 502-509. PMID: 11476588, DOI: 10.1006/dbio.2001.0343.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsSperm-egg interactionLateral mobilityPlasma membranePlasma membrane bindingHead plasma membraneEpididymal spermPopulation of cellsFertilinMembrane bindingFluorescence redistributionHead domainMembrane bilayerAcrosome-intact spermEpididymal passageAcrosome-reacted spermSpermAcrosome reactionCauda epididymisMembraneCellsInteractionAcrosomeCapacitationBindingPhotobleaching
1998
Neural Crest-Specific and General Expression of Distinct Metalloprotease–Disintegrins in EarlyXenopus laevisDevelopment
Cai H, Krätzschmar J, Alfandari D, Hunnicutt G, Blobel C. Neural Crest-Specific and General Expression of Distinct Metalloprotease–Disintegrins in EarlyXenopus laevisDevelopment. Developmental Biology 1998, 204: 508-524. PMID: 9882486, DOI: 10.1006/dbio.1998.9017.Peer-Reviewed Original ResearchCitations
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Fitkin Memorial Pavilion, 789 Howard Ave
New Haven, CT 06519
United States
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Fitkin Memorial Pavilion
789 Howard Avenue
New Haven, CT 06519