Elizabeth Perry
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Associate Research Scientist in Biostatistics
Appointments
Biostatistics
Associate Research ScientistPrimary
Other Departments & Organizations
- Biostatistics
- Townsend Lab
- Yale School of Public Health
Research
Research at a Glance
Publications Timeline
A big-picture view of Elizabeth Perry's research output by year.
8Publications
884Citations
Publications
2015
A Quantitative System for Studying Metastasis Using Transparent Zebrafish
Heilmann S, Ratnakumar K, Langdon E, Kansler E, Kim I, Campbell N, Perry E, McMahon A, Kaufman C, van Rooijen E, Lee W, Iacobuzio-Donahue C, Hynes R, Zon L, Xavier J, White R. A Quantitative System for Studying Metastasis Using Transparent Zebrafish. Cancer Research 2015, 75: 4272-4282. PMID: 26282170, PMCID: PMC4609292, DOI: 10.1158/0008-5472.can-14-3319.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSingle-cell resolutionStable cell linesZebrafish systemTransparent zebrafishMetastasis-initiating cellsHuman cell culture systemsHigh-throughput investigationCell culture systemComputational image analysisMetastatic biologyMetastatic capabilityCell linesMetastatic capacityMelanoma cellsMetastatic processRapid generationCulture systemSuperior imaging toolCellsMitfaZebrafishMetastasis ScoreDegree of pigmentationBiologyProgenyThe Molecular and Genetic Basis of Repeatable Coevolution between Escherichia coli and Bacteriophage T3 in a Laboratory Microcosm
Perry E, Barrick J, Bohannan B. The Molecular and Genetic Basis of Repeatable Coevolution between Escherichia coli and Bacteriophage T3 in a Laboratory Microcosm. PLOS ONE 2015, 10: e0130639. PMID: 26114300, PMCID: PMC4482675, DOI: 10.1371/journal.pone.0130639.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsBacteriophage T3Repeatable evolutionEscherichia coli BCoevolution experimentMutant phageFunction mutationsColi BLevel of pathwaysNucleotide levelLaboratory microcosmsPhage tail fibersSame ancestral strainBacterial ancestorAncestral phageConvergent evolutionContinuous culture deviceGenomic changesGenetic basisSingle codonNew phage typePhage interactionsDifferent genesTail fibersAncestral strainGenetic changes
2010
Ecology of Speciation in the Genus Bacillus▿ †
Connor N, Sikorski J, Rooney A, Kopac S, Koeppel A, Burger A, Cole S, Perry E, Krizanc D, Field N, Slaton M, Cohan F. Ecology of Speciation in the Genus Bacillus▿ †. Applied And Environmental Microbiology 2010, 76: 1349-1358. PMID: 20048064, PMCID: PMC2832372, DOI: 10.1128/aem.01988-09.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsEcotype SimulationSoil textureEvolutionary historyEcology of speciationClade's evolutionary historyB. subtilisDNA sequence diversityPutative ecotypesEcological divergenceDivergent lineagesMicrobial ecologistsEcological changesEcological diversityEcological differencesEcological dimensionsEcotype differencesSequence diversityTemperature adaptationGenus BacillusSolar exposureCladeEcotypesEnvironmental parametersBacterial populationsTaxa
2008
Identifying the fundamental units of bacterial diversity: A paradigm shift to incorporate ecology into bacterial systematics
Koeppel A, Perry E, Sikorski J, Krizanc D, Warner A, Ward D, Rooney A, Brambilla E, Connor N, Ratcliff R, Nevo E, Cohan F. Identifying the fundamental units of bacterial diversity: A paradigm shift to incorporate ecology into bacterial systematics. Proceedings Of The National Academy Of Sciences Of The United States Of America 2008, 105: 2504-2509. PMID: 18272490, PMCID: PMC2268166, DOI: 10.1073/pnas.0712205105.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsBacterial systematicsNatural communitiesSequence-based approachesEvolution CanyonBacterial domainEcotype SimulationSuch ecotypesMicrobial ecologyDistinct lineagesMultiple ecotypesEvolutionary dynamicsBacterial diversityDifferent solar exposureTraditional speciesBacterial populationsBacterial ecologyEcotypesBacterial cellsEcologyDistinct rolesSystematicsFundamental unitDiverse setCladeLineages
2007
A Systematics for Discovering the Fundamental Units of Bacterial Diversity
Cohan F, Perry E. A Systematics for Discovering the Fundamental Units of Bacterial Diversity. Current Biology 2007, 17: r373-r386. PMID: 17502094, DOI: 10.1016/j.cub.2007.03.032.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsBacterial diversityHistory of coexistenceBacterial evolutionBacterial systematistsMicrobial worldSpecies unitsBacterial systematicsEvolutionary dynamicsDNA sequencesBiological diversityFundamental unitTremendous diversitySequence clustersBacterial speciesEvolutionary propertiesEvolutionary theoryMolecular techniquesDiversitySpeciesSystematistsDistinct groupsSystematicsPlantsSequenceMicrobiologistsMass spectrometric analysis of lipopeptides from Bacillus strains isolated from diverse geographical locations
Price N, Rooney A, Swezey J, Perry E, Cohan F. Mass spectrometric analysis of lipopeptides from Bacillus strains isolated from diverse geographical locations. FEMS Microbiology Letters 2007, 271: 83-89. PMID: 17419767, DOI: 10.1111/j.1574-6968.2007.00702.x.Peer-Reviewed Original ResearchCitations
2006
Adaptive Mutations In RNA-Based Regulatory Mechanisms: Computational and Experimental Investigations
Barash D, Sikorski J, Perry E, Nevo E, Nudler E. Adaptive Mutations In RNA-Based Regulatory Mechanisms: Computational and Experimental Investigations. Israel Journal Of Ecology And Evolution 2006, 52: 263-279. DOI: 10.1560/ijee_52_3-4_263.Peer-Reviewed Original ResearchCitationsConceptsTPP riboswitchRegulatory mechanismsEvolution CanyonTermination efficiencyTranscription terminationNorth-facing slopesAdaptive mutationsEvolutionary time scalesGenetic control elementsRNA genetic control elementsBeneficial fitness effectsClass of RNAsMesic north-facing slopeParticipation of proteinsLevel of RNAModel systemOrganism's fitnessFitness effectsBeneficial mutationsTranslation initiationAncient originGC contentNonrandom mutationsPromoter regionMutational differencesIdentifying the Fundamental Units of Diversity Among Bacillus Isolates From "Evolution Canyon" III
Perry E, Koeppel A, Krizanc D, Rooney A, Sikorski J, Nevo E, Cohan F. Identifying the Fundamental Units of Diversity Among Bacillus Isolates From "Evolution Canyon" III. Israel Journal Of Ecology And Evolution 2006, 52: 543-552. DOI: 10.1560/ijee_52_3-4_543.Peer-Reviewed Original ResearchCitationsConceptsBacterial systematicsEvolution CanyonDistinct populationsSequence diversity patternsDNA sequence diversityLineage-specific ratesSingle bacterial speciesEcological distinctnessFundamental unitPutative ecotypesMicrobial ecologistsDiversity patternsDistinct lineagesEcological diversityDifferent microhabitatsSequence evolutionSequence dataSequence diversityBacterial diversityCladeSequence clustersBacterial speciesBacillus subtilisBacillus isolatesEvolutionary simulations