Diana Núñez
Associate Research ScientistAbout
Research
Publications
2026
Decoding the role of transcriptomic clocks in the human prefrontal cortex
Martínez-Magaña J, Vlot A, Sullivan K, Jacobson D, Krystal J, Girgenti M, Núnez-Ríos D, Andrade-Brito D, Merlet J, Townsend A, Wells A, Alvarez C, Lane M, Holtzheimer P, Group T, Walss-Bass C, Montalvo-Ortiz J. Decoding the role of transcriptomic clocks in the human prefrontal cortex. IScience 2026, 29: 116439. PMID: 42491807, PMCID: PMC13378135, DOI: 10.1016/j.isci.2026.116439.Peer-Reviewed Original ResearchA large-scale meta-analysis of DNA methylation signatures of alcohol use disorder in the Psychiatric Genomics Consortium
Zillich L, D’Augello S, Avetyan D, Delgado G, Gizer I, Jung J, Katrinli S, Kleber M, Merrill N, Moissl-Blanke A, Núñez-Rios D, Otto J, Zillich E, Friedel E, Hancock D, Johnson E, Martínez-Magaña J, Sosnowski D, White J, Aberg K, Copeland W, Diazgranados N, Fani N, Gelernter J, Goldman D, Foo J, Kranzler H, Levey D, März W, Penninx B, Polimanti R, Powers A, Smith A, Spanagel R, van den Oord E, Wilhelmsen K, Witt S, Domschke K, Schiele M, Maher B, Montalvo Ortiz J, Clark S, Lohoff F. A large-scale meta-analysis of DNA methylation signatures of alcohol use disorder in the Psychiatric Genomics Consortium. Nature Mental Health 2026, 4: 1088-1098. DOI: 10.1038/s44220-026-00666-w.Peer-Reviewed Original ResearchDeleterious coding variation associated with autism is shared across ancestries
Natividad Avila M, Jung S, Satterstrom F, Fu J, Levy T, Sloofman L, Klei L, Pichardo T, Marquez D, Stevens C, Cusick C, Ames J, Campos G, Cerros H, Chaskel R, Costa C, Cuccaro M, Lopez A, Fernandez M, Ferro E, Galeano L, Girardi A, Griswold A, Hernandez L, Lourenço N, Ludena Y, Núñez-Ríos D, Oyama R, Peña K, Pessah I, Schmidt R, Sweeney H, Tolentino L, Wang J, Albores-Gallo L, Croen L, Cruz-Fuentes C, Hertz-Picciotto I, Kolevzon A, Lattig M, Mayo L, Passos-Bueno M, Pericak-Vance M, Siper P, Tassone F, Trelles M, Talkowski M, Daly M, Mahjani B, De Rubeis S, Cook E, Roeder K, Betancur C, Devlin B, Buxbaum J. Deleterious coding variation associated with autism is shared across ancestries. Nature Medicine 2026, 32: 1519-1529. PMID: 41912808, PMCID: PMC13099431, DOI: 10.1038/s41591-026-04228-6.Peer-Reviewed Original Research
2025
Integrated Gene and Isoform-Level Transcriptomic Analysis of Adverse Childhood Experiences in the Human Prefrontal Cortex
Núñez-Ríos D, Nagamatsu S, Martínez-Magaña J, Montalvo-Ortiz J. Integrated Gene and Isoform-Level Transcriptomic Analysis of Adverse Childhood Experiences in the Human Prefrontal Cortex. The Yale Journal Of Biology And Medicine 2025, 98: 89-103. PMID: 40589944, PMCID: PMC12204229, DOI: 10.59249/vlmz6974.Peer-Reviewed Original ResearchPsychiatric genetics in the diverse landscape of Latin American populations
Bruxel E, Rovaris D, Belangero S, Chavarría-Soley G, Cuellar-Barboza A, Martínez-Magaña J, Nievergelt C, Núñez-Ríos D, Ota V, Peterson R, Sloofman L, Adams A, Albino E, Alvarado A, Andrade-Brito D, Arguello-Pascualli P, Bandeira C, Bau C, Bulik C, Buxbaum J, Cappi C, Corral-Frias N, Corrales A, Corsi-Zuelli F, Crowley J, Cupertino R, da Silva B, De Almeida S, De la Hoz J, Forero D, Fries G, Gelernter J, González-Giraldo Y, Grevet E, Grice D, Hernández-Garayua A, Hettema J, Ibáñez A, Ionita-Laza I, Lattig M, Lima Y, Lin Y, López-León S, Loureiro C, Martínez-Cerdeño V, Martínez-Levy G, Melin K, Moreno-De-Luca D, Muniz Carvalho C, Olivares A, Oliveira V, Ormond R, Palmer A, Panzenhagen A, Passos-Bueno M, Peng Q, Pérez-Palma E, Prieto M, Roussos P, Sanchez-Roige S, Santamaría-García H, Shansis F, Sharp R, Storch E, Tavares M, Tietz G, Torres-Hernández B, Tovo-Rodrigues L, Trelles P, Trujillo-ChiVacuan E, Velásquez M, Vera-Urbina F, Voloudakis G, Wegman-Ostrosky T, Zhen-Duan J, Zhou H, Santoro M, Nicolini H, Atkinson E, Giusti-Rodríguez P, Montalvo-Ortiz J. Psychiatric genetics in the diverse landscape of Latin American populations. Nature Genetics 2025, 57: 1074-1088. PMID: 40175716, PMCID: PMC12133068, DOI: 10.1038/s41588-025-02127-z.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2024
Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: a meta-analysis of 23 military and civilian cohorts
Katrinli S, Wani A, Maihofer A, Ratanatharathorn A, Daskalakis N, Montalvo-Ortiz J, Núñez-Ríos D, Zannas A, Zhao X, Aiello A, Ashley-Koch A, Avetyan D, Baker D, Beckham J, Boks M, Brick L, Bromet E, Champagne F, Chen C, Dalvie S, Dennis M, Fatumo S, Fortier C, Galea S, Garrett M, Geuze E, Grant G, Hauser M, Hayes J, Hemmings S, Huber B, Jajoo A, Jansen S, Kessler R, Kimbrel N, King A, Kleinman J, Koen N, Koenen K, Kuan P, Liberzon I, Linnstaedt S, Lori A, Luft B, Luykx J, Marx C, McLean S, Mehta D, Milberg W, Miller M, Mufford M, Musanabaganwa C, Mutabaruka J, Mutesa L, Nemeroff C, Nugent N, Orcutt H, Qin X, Rauch S, Ressler K, Risbrough V, Rutembesa E, Rutten B, Seedat S, Stein D, Stein M, Toikumo S, Ursano R, Uwineza A, Verfaellie M, Vermetten E, Vinkers C, Ware E, Wildman D, Wolf E, Young R, Zhao Y, van den Heuvel L, Uddin M, Nievergelt C, Smith A, Logue M. Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: a meta-analysis of 23 military and civilian cohorts. Genome Medicine 2024, 16: 147. PMID: 39696436, PMCID: PMC11658418, DOI: 10.1186/s13073-024-01417-1.Peer-Reviewed Original ResearchAncestral origins of TYR and OCA2 gene mutations in oculocutaneous albinism from two admixed populations in Colombia
Cárdenas W, Conley A, Nagar S, Núñez-Ríos D, Jordan I, Lattig M. Ancestral origins of TYR and OCA2 gene mutations in oculocutaneous albinism from two admixed populations in Colombia. PLOS ONE 2024, 19: e0313777. PMID: 39556609, PMCID: PMC11573203, DOI: 10.1371/journal.pone.0313777.Peer-Reviewed Original ResearchNeuronal-specific methylome and hydroxymethylome analysis reveal significant loci associated with alcohol use disorder
Andrade-Brito D, Núñez-Ríos D, Martínez-Magaña J, Rompala G, Zillich L, Witt S, Clark S, Lattig M, Montalvo-Ortiz J, Alvarez V, Benedek D, Che A, Cruz D, Davis D, Girgenti M, Hoffman E, Holtzheimer P, Huber B, Kaye A, Keane T, Krystal J, Labadorf A, Logue M, Marx B, Mash D, McKee A, Miller M, Montalvo-Ortiz J, Noller C, Schnurr P, Scott W, Stein T, Ursano R, Williamson D, Wolf E, Young K. Neuronal-specific methylome and hydroxymethylome analysis reveal significant loci associated with alcohol use disorder. Frontiers In Genetics 2024, 15: 1345410. PMID: 38633406, PMCID: PMC11021708, DOI: 10.3389/fgene.2024.1345410.Peer-Reviewed Original Research
2023
Profiling neuronal methylome and hydroxymethylome of opioid use disorder in the human orbitofrontal cortex
Rompala G, Martínez-Magaña J, Nuñez-Ríos D, Wang J, Girgenti M, Krystal J, Gelernter J, Hurd Y, Montalvo-Ortiz J. Profiling neuronal methylome and hydroxymethylome of opioid use disorder in the human orbitofrontal cortex. Nature Communications 2023, 14: 4544. PMID: 37507366, PMCID: PMC10382503, DOI: 10.1038/s41467-023-40285-y.Peer-Reviewed Original ResearchCross-Species Convergence of Brain Transcriptomic and Epigenomic Findings in Posttraumatic Stress Disorder: A Systematic Review
Núñez-Rios D, Martínez-Magaña J, Krystal J, Martínez-González K, Giusti-Rodríguez P, Montalvo-Ortiz J. Cross-Species Convergence of Brain Transcriptomic and Epigenomic Findings in Posttraumatic Stress Disorder: A Systematic Review. Complex Psychiatry 2023, 9: 100-118. PMID: 37404872, PMCID: PMC10315001, DOI: 10.1159/000529536.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
Get In Touch
Contacts
Email