Darpan Kayastha, MD
Cards
About
Research
Publications
2024
Restarting Antithrombotic Therapies After Endoscopic Sinus Surgery: A Systematic Review
Boyi T, Richmond R, Kayastha D, Manes R, Rimmer R. Restarting Antithrombotic Therapies After Endoscopic Sinus Surgery: A Systematic Review. Annals Of Otology Rhinology & Laryngology 2024, 133: 633-638. PMID: 38557289, DOI: 10.1177/00034894241245840.Peer-Reviewed Original ResearchEndoscopic sinus surgeryAntithrombotic therapySinus surgerySystematic reviewResumption of antithrombotic therapyRisk of perioperative hemorrhageFull-text reviewPreferred Reporting ItemsCase-control studyWeb of ScienceCINAHL databasesReporting ItemsIndependent reviewersUnique articlesPerioperative hemorrhageTherapy resumptionCohort studyAntiplatelet therapyInclusion criteriaPatient morbidityAntiplatelet agentsPrimary outcomeTherapySurgeryAntiplateletEnvironmental Impact of a Direct Laryngoscopy: Opportunities for Pollution Mitigation
Filley G, Kayastha D, Hayes W, Mehra S, Sherman J, Eckelman M. Environmental Impact of a Direct Laryngoscopy: Opportunities for Pollution Mitigation. The Laryngoscope 2024, 134: 3206-3214. PMID: 38379176, DOI: 10.1002/lary.31341.Peer-Reviewed Original ResearchGlobal warming potentialLife cycle assessmentEnvironmental impact categoriesImpact categoriesEnvironmental impactWater consumptionAlternative scenariosCycle assessmentPollution mitigationWarming potentialHuman healthDecontamination standardsNon-sterileYale-New Haven HospitalEnvironmental benefitsDecontaminationTertiary medical centerWaterSteam sterilizationCenters for Disease Control (CDCPollutionHigh-level disinfectionSurgical proceduresDirect laryngoscopySurgical towels
2023
3D printing for virtual surgical planning of nasoseptal flap skull‐base reconstruction: A proof‐of‐concept study
Kayastha D, Wiznia D, Manes R, Omay S, Khoury T, Rimmer R. 3D printing for virtual surgical planning of nasoseptal flap skull‐base reconstruction: A proof‐of‐concept study. International Forum Of Allergy & Rhinology 2023, 13: 2073-2075. PMID: 37026426, DOI: 10.1002/alr.23165.Peer-Reviewed Original ResearchAdverse Events Associated With Bioabsorbable Nasal Implants: A MAUDE Database Analysis
Wilkins S, Sheth A, Kayastha D, Abdou H, Salehi P, Citardi M, Manes R. Adverse Events Associated With Bioabsorbable Nasal Implants: A MAUDE Database Analysis. Otolaryngology 2023, 168: 1253-1257. PMID: 36939542, DOI: 10.1002/ohn.227.Peer-Reviewed Original ResearchConceptsAdverse eventsNasal implantsPotential long-term complicationsMAUDE Database AnalysisLong-term complicationsPain/discomfortUser Facility Device Experience (MAUDE) databaseNasal valve collapseSteroid injectionTreatment sequelaeStandardized reporting templateCommon symptomsAdverse reactionsPathologic analysisValve collapseImplant protrusionAdjacent tissuesMAUDE databaseDevice reportsReporting templateDatabase analysisBioabsorbable implantsComplicationsImplantsExperience database
2022
Trends in Billing and Medicare Reimbursement for In-Office Cerumen Removal by Otolaryngologists and Other Providers
Patel R, Torabi S, Kasle D, Kayastha D, Manes R. Trends in Billing and Medicare Reimbursement for In-Office Cerumen Removal by Otolaryngologists and Other Providers. Annals Of Otology Rhinology & Laryngology 2022, 132: 410-416. PMID: 35894062, DOI: 10.1177/00034894221096980.Peer-Reviewed Original ResearchConceptsAdvanced practice providersGeneral physiciansProvider typeCerumen removalMedicare reimbursementRural settingsTotal Medicare reimbursementRetrospective studyPractice providersMedicare Part BOtolaryngologistsNumber of otolaryngologistsBilling patternsNumber of providersPhysiciansProvider UtilizationPatientsReimbursementMedical practiceMedicare Utilization and Reimbursement Variation Between Rural and Urban Otolaryngologists
Patel R, Torabi S, Kayastha D, Kuan E, Manes R. Medicare Utilization and Reimbursement Variation Between Rural and Urban Otolaryngologists. Otolaryngology 2022, 168: 528-535. PMID: 35852873, DOI: 10.1177/01945998221113550.Peer-Reviewed Original ResearchConceptsMedicare patientsRetrospective cross-sectional studyPatient's comorbidity profileHealthcare Common Procedure Coding System codesNumber of patientsCross-sectional studyReimbursement variationComorbidity profilesPatient populationRisk scoreMedicare Provider UtilizationLarge urban settingUrban settingsOlder ageMore Medicare patientsPhysician populationPatientsPhysiciansComplexity of proceduresHCPCS codesProvider UtilizationReimbursement ratesOtolaryngologyRural practiceMedicare utilization
2021
Procedural and geographic variation in price markup of common rhinology procedures by otolaryngologists in the United States
Patel R, Torabi S, Kasle D, Kayastha D, Manes R. Procedural and geographic variation in price markup of common rhinology procedures by otolaryngologists in the United States. International Forum Of Allergy & Rhinology 2021, 12: 227-232. PMID: 34569169, DOI: 10.1002/alr.22893.Peer-Reviewed Original Research
2019
Crosstalk between leukocytes triggers differential immune responses against Salmonella enterica serovars Typhi and Paratyphi
Salerno-Goncalves R, Kayastha D, Fasano A, Levine MM, Sztein MB. Crosstalk between leukocytes triggers differential immune responses against Salmonella enterica serovars Typhi and Paratyphi. PLOS Neglected Tropical Diseases 2019, 13: e0007650. PMID: 31412039, PMCID: PMC6709971, DOI: 10.1371/journal.pntd.0007650.Peer-Reviewed Original ResearchConceptsSalmonella enterica serovar TyphiParatyphi AEnterica serovar TyphiIL-8Paratyphi BEpithelial cellsSerovar TyphiCytokines/chemokinesPro-inflammatory cytokinesDifferential immune responsesLife-threatening illnessHuman intestinal mucosaSimilar clinical symptomsPolymorphonuclear leukocyte migrationInnate cellsClinical symptomsEnteric feverIL-1βIL-6Three-dimensional organotypic modelImmune responseIntestinal mucosaDistinct epidemiologyLeukocyte migrationSecretion patternThe evolving roles of computer-based technology and smartphone applications in facial plastic surgery.
Kayastha D, Vakharia KT. The evolving roles of computer-based technology and smartphone applications in facial plastic surgery. Current Opinion In Otolaryngology & Head & Neck Surgery 2019, 27: 267-273. PMID: 31157662, DOI: 10.1097/moo.0000000000000557.Peer-Reviewed Original Research