2016
Neisseria cinerea isolates can adhere to human epithelial cells by type IV pilus-independent mechanisms
Wörmann ME, Horien CL, Johnson E, Liu G, Aho E, Tang CM, Exley RM. Neisseria cinerea isolates can adhere to human epithelial cells by type IV pilus-independent mechanisms. Microbiology 2016, 162: 487-502. PMID: 26813911, PMCID: PMC4891991, DOI: 10.1099/mic.0.000248.Peer-Reviewed Original ResearchMeSH KeywordsAdhesins, BacterialBacterial AdhesionCell LineEpithelial CellsFimbriae ProteinsGene DeletionHumansNeisseria cinereaNeisseria meningitidisConceptsHuman epithelial cellsN. cinereaFunction of piliEpithelial cellsType IV piliPathogen Neisseria meningitidisHost-pathogen interactionsClose taxonomic relationshipFormation of microcoloniesPilus-pilus interactionsGenome analysisTaxonomic relationshipsMajor pilinTfp expressionPilin expressionSpecies sharesPilin genePathogenic NeisseriaNon-pathogenic Neisseria speciesCell surfaceNeisseria cinereaCinereaRole of TFPGenesNon-pathogenic Neisseria
2014
Sequence, distribution and chromosomal context of class I and class II pilin genes of Neisseria meningitidis identified in whole genome sequences
Wörmann ME, Horien CL, Bennett JS, Jolley KA, Maiden MC, Tang CM, Aho EL, Exley RM. Sequence, distribution and chromosomal context of class I and class II pilin genes of Neisseria meningitidis identified in whole genome sequences. BMC Genomics 2014, 15: 253. PMID: 24690385, PMCID: PMC4023411, DOI: 10.1186/1471-2164-15-253.Peer-Reviewed Original ResearchConceptsWhole genome sequencesPilE geneGenome sequenceChromosomal contextAntigenic variationHorizontal transferPilin subunitPilin geneAvailable whole genome sequencesDNA sequence motifsAmino acid sequence variationAmino acid sequenceMajor pilin subunitClass II pilinsPilin antigenic variationGene EncodesGenomic organizationHigh-frequency gene conversionsGenomic contextGene conversionSequence motifsAcid sequenceSequence variationSubunit variationTerms of sequences