Molecular surveillance on Streptococcus pneumoniae carriage in non-elderly adults; little evidence for pneumococcal circulation independent from the reservoir in children
Wyllie AL, Rümke LW, Arp K, Bosch AA, Bruin JP, Rots NY, Wijmenga-Monsuur AJ, Sanders EA, Trzciński K. Molecular surveillance on Streptococcus pneumoniae carriage in non-elderly adults; little evidence for pneumococcal circulation independent from the reservoir in children. Scientific Reports 2016, 6: 34888. PMID: 27713565, PMCID: PMC5054371, DOI: 10.1038/srep34888.Peer-Reviewed Original ResearchConceptsCarriage rateNasopharyngeal swabsOral samplesUpper respiratory tract samplesVaccine herd effectsStreptococcus pneumoniae carriageRespiratory tract samplesHigh carriage rateNon-elderly adultsS. pneumoniae detectionAge-associated differencesEntire adult populationChildless adultsSerotype replacementPneumoniae carriagePneumococcal carriageTract samplesCarriage frequencyStreptococcus pneumoniaeAdult populationSerotype 3Gold standard culture methodMolecular surveillanceMolecular testsGold standard