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Robert Bazell

January 27, 2021
  • 00:09Hello and welcome to Science et al podcast,
  • 00:12but everything science sponsored
  • 00:13by the Yale School of Medicine.
  • 00:15I'm your host, Daniel Barron.
  • 00:17And in this episode I'm
  • 00:19speaking with Robert Bazell.
  • 00:20Robert or Bob as he asked me to call him,
  • 00:24worked his NBC's chief science
  • 00:25correspondent for 38 years.
  • 00:27In that capacity, Bob and many awards,
  • 00:29including five Emmy Awards,
  • 00:30the Peabody Award, and the DuPont Award.
  • 00:33He also authored a bestselling
  • 00:34book called her two,
  • 00:35The Making of a revolutionary
  • 00:37treatment for breast Cancer,
  • 00:38which was adapted as a TV film.
  • 00:42Now Bob is supposedly formally retired,
  • 00:44even though he's quite busy at
  • 00:46yells Department of Molecular
  • 00:48Cellular and Developmental Biology,
  • 00:50where he spends his time mentoring
  • 00:52aspiring journalist scientists.
  • 00:53An anyone who wants to communicate
  • 00:56more effectively with the public,
  • 00:58including myself.
  • 00:59I ran into Bob's Science
  • 01:01journalism panel at Yale,
  • 01:02where he was one of the primary panelists.
  • 01:05I had never met him in person
  • 01:07and didn't recognize him,
  • 01:09but instantly recognized his voice.
  • 01:11And after the panel discussion,
  • 01:13I Googled Bob and reviewed
  • 01:15some of his videos,
  • 01:16some of which I still
  • 01:18remembered from decades before.
  • 01:19It was kind of strange to see him
  • 01:22with Bill Clinton and a lot of
  • 01:25the AIDS and cancer treatments
  • 01:26and the Human Genome Project.
  • 01:29It was really, it was really.
  • 01:31It was really fascinating.
  • 01:32Bob's had an enormous impact,
  • 01:34only that I and I suppose many of
  • 01:37listeners think about and appreciate science.
  • 01:40It was a real honor to speak with Bob
  • 01:43about his work and to see from his eyes at,
  • 01:46you know,
  • 01:46the 10,000 foot view how he views
  • 01:48science and how science meshes
  • 01:50with politics and public policy,
  • 01:52social movements and with the
  • 01:54scientific community itself.
  • 01:55So here we go.
  • 01:56Thanks again to
  • 02:07Well, thank you for coming and for
  • 02:09letting me pick your brain yet again.
  • 02:12It was really interesting so I
  • 02:15had not really met you formally,
  • 02:17but I first I could say heard your
  • 02:20voice from the back of a lecture
  • 02:22Hall during a panel discussion with
  • 02:25Carl Zimmer Anneliese Sanders,
  • 02:27an I recognized your voice.
  • 02:30Really quite quickly actually.
  • 02:31So I was like, oh, wow,
  • 02:33I know this guy and so after that I just
  • 02:37I did what I think by your definition
  • 02:40would be a not quite a deep dive but.
  • 02:44Dipping my toe in the finger
  • 02:46of your huge body of work.
  • 02:48And obviously you've reported on
  • 02:51far more than 4000 stories and I
  • 02:54was able to go on to NBC's website
  • 02:56and watch some of the videos that
  • 02:59you had made like some of the
  • 03:01reporting you did for the TV.
  • 03:04By
  • 03:04the way, if you want to see videos
  • 03:07from history, you can open the
  • 03:10Yale Library and Vanderbilt.
  • 03:13Library has an archive of every television
  • 03:15show that's been produced since 1968,
  • 03:17and you go live stream it. I had no idea,
  • 03:20so you can watch just everything.
  • 03:22You can watch everything.
  • 03:24Well, let's pick a moment in
  • 03:26history that's kind of scary.
  • 03:27Actually, there's
  • 03:28a lot of junk on television. There's a
  • 03:31lot of junk, but it also is for me.
  • 03:34It's been a very useful
  • 03:35tool for undergraduates,
  • 03:36because if I'm teaching a course on,
  • 03:39say, the history of HIV AIDS,
  • 03:41which I'm doing now, or.
  • 03:43Events in public health that I take it back,
  • 03:46take them back and show them these.
  • 03:49Videos 'cause I wouldn't have access to them.
  • 03:51NBC owns them, but I can show it,
  • 03:53show it to them and they are absolutely
  • 03:56fascinated to hear the inside story of.
  • 03:58How this happened and then to see
  • 04:00the people that they're not just
  • 04:02reading about it in an article or
  • 04:05at a Journal article or a popular
  • 04:07article, many of whom you interviewed?
  • 04:08Yeah, why didn't they see me interviewing
  • 04:10them and then I can tell them
  • 04:12what they're really like.
  • 04:14This person was a decent person.
  • 04:15This one is not one of the videos,
  • 04:18so there are 480 videos on the NBC website,
  • 04:21so this is 10 to what I did.
  • 04:23Sure right, but you know,
  • 04:24it's still a lot for me and
  • 04:26there's one video in particular.
  • 04:28It was from 1981.
  • 04:29Where you had this excellent white linen
  • 04:32sports coat and purple tie purple shirt,
  • 04:35your hairs gotta fro delivery.
  • 04:36Bring all that up.
  • 04:39Great, so great and you're interviewing
  • 04:41BF Skinner about some experiments
  • 04:43that he's doing with pigeons.
  • 04:45You know unpacking and, well,
  • 04:47you know the different files and stuff.
  • 04:50I had a great honor and for a long time on
  • 04:53the Today Show in the 80s where I they won't,
  • 04:57they took a science segment which is
  • 05:00very rare an I was allowed to pick and
  • 05:03anything I wanted to and I found out
  • 05:06that Skinner was still around, which was
  • 05:08surprising because it was so famous.
  • 05:11And he was a great interview.
  • 05:14It was a very wry sense of
  • 05:16humor and the funny character.
  • 05:18And he had this idea of everything.
  • 05:20Everything as I recently started
  • 05:22wearing hearing aids myself.
  • 05:23But in those days,
  • 05:25hearing aids were quite visible and he,
  • 05:27being the behaviorist that he was,
  • 05:29he told me that the effect of
  • 05:31hearing aid seems to be it made
  • 05:34people scream at him 'cause
  • 05:35they would see it here.
  • 05:39Operant conditioning.
  • 05:40He didn't think the hearing aids
  • 05:42were enhancing his hearing,
  • 05:43but he may make people screw you.
  • 05:45Wow that would have been
  • 05:47such a wonderful experience.
  • 05:48I've obviously never met Skinner,
  • 05:50but I've read a lot of his
  • 05:52work and seeing how it
  • 05:54influences and he had some
  • 05:56students that I followed up with
  • 05:58who made enormous fan of all.
  • 06:00Of other people, for instance,
  • 06:02people were trying to teach
  • 06:03a language to chimpanzees,
  • 06:05and they proved that they could
  • 06:07get pigeons to do exactly what
  • 06:09these people are getting the
  • 06:11chimpanzees to do.
  • 06:12Pressing the buttons,
  • 06:13community communicating
  • 06:13right exactly spelling out
  • 06:15words which really weren't really doing
  • 06:17well. There was such as a light going
  • 06:20through a lot of your work and I wanted
  • 06:23to kind of start farther back because
  • 06:25I find it absolutely fascinating.
  • 06:27So you did your undergraduate
  • 06:29work and Berkeley.
  • 06:30Seemingly at a time when there was like huge.
  • 06:36Protest political unrest.
  • 06:37You know the 60 seven was it when
  • 06:40you graduated, graduated in 67.
  • 06:42I started in the fall of 60 three and
  • 06:44the free Speech movement was in 64 and
  • 06:47Berkeley was way ahead of the rest of the
  • 06:51country in terms of being disruptive.
  • 06:53And I had my eye on my own back.
  • 06:56Story to that is that I had dropped
  • 06:58out of high school an I worked
  • 07:01as a merchant Seaman for awhile.
  • 07:03I'm traveling around the Pacific
  • 07:05so I got that. I got to Berkeley.
  • 07:08I got the equivalent of GD and
  • 07:11I went to Berkeley
  • 07:12and I'm sorry can we step back?
  • 07:14Can you help me understand
  • 07:15what a merchant Seaman is?
  • 07:17Oh I have this vision of EB
  • 07:19White working on a cruise
  • 07:21vessel going up to Alaska or
  • 07:23something was not that different.
  • 07:24I was in a cooks and stewards union
  • 07:27so that I wash dishes at sometimes
  • 07:29if I got a good job you would
  • 07:31bid on jobs at the Union Hall.
  • 07:33If I got a good job I would
  • 07:36be able to wait on tables or.
  • 07:40Sometimes I had to clean up rooms,
  • 07:42it was it was interesting mixture
  • 07:44of things and sometimes it worked
  • 07:46on freighters which were much
  • 07:48more less contact with the public.
  • 07:50But this was long enough ago that
  • 07:53there were American passenger ships,
  • 07:55so people were traveling to Hawaii
  • 07:57and Australia and Tahiti on ships was
  • 07:59quite an experience, so I was a bit.
  • 08:04In front of my classmates when I got there.
  • 08:07In terms of life experience and
  • 08:10so that made me right away.
  • 08:13Wine, wonder why these people are
  • 08:15wasting their time protesting?
  • 08:16Not that I disagree with the politics,
  • 08:18but in retrospect a lot of them
  • 08:20are very brave people who had gone
  • 08:23to the Mississippi freedom Summers
  • 08:25and put their lives on the line.
  • 08:27And but when they came back they wanted
  • 08:29to pick a fight with the University,
  • 08:32and in retrospect,
  • 08:33a lot of it was kind of silly at the
  • 08:36time was whether you put a table
  • 08:39here or 30 feet away from there
  • 08:41an to give out pamphlets so.
  • 08:43I had trouble at first getting used to it,
  • 08:46and I think that the politics of Berkeley.
  • 08:49Played a lot in my ending up
  • 08:51being a journalist because.
  • 08:53It was always very disruptive Ann.
  • 08:56It was hard to concentrate, I didn't.
  • 09:00I had was on track to be a scientist,
  • 09:04I an I went away for a year and worked
  • 09:07at the University of Sussex and then came
  • 09:10back which allowed me to stay in Berkeley.
  • 09:13Usually you have to do your
  • 09:15graduate work someplace else,
  • 09:16but keeping on the track to
  • 09:18do what I had to do,
  • 09:20I went to work in the laboratory
  • 09:22of a Nobel Prize winner and this
  • 09:25he was Melvin Calvin who discovered
  • 09:27the photosynthesis cycle which
  • 09:29is now known as the Calvin Cycle.
  • 09:31But of course it wasn't in those days.
  • 09:34Anne.
  • 09:35He had a huge labion 20 combination
  • 09:38of graduate students and postdocs.
  • 09:41Ann,
  • 09:41we decided in because that was the
  • 09:44way we did things in those days too.
  • 09:48Demand that he get off the Board of
  • 09:50Directors of Dow Chemical because
  • 09:52it made napalm.
  • 09:53An he said to us,
  • 09:56do go to hell just you're fired, he fired.
  • 10:00All of us just called his name
  • 10:01is student newspapers called the
  • 10:03Saturday Night Massacre.
  • 10:04So this is when you are Berkeley
  • 10:06hours Berkeley. So I was right.
  • 10:08This is what I was pushed.
  • 10:10Fast forwarding to undergraduate student.
  • 10:11K and I had finished by.
  • 10:14Or else for my PhD and I was about
  • 10:16to thinking about it thesis and at
  • 10:18that moment I happened just fortuitously
  • 10:20to meet somebody from Science magazine,
  • 10:23and that's how I got into journalism.
  • 10:25But if it hadn't met,
  • 10:27Melvin Calvin hadn't kicked me
  • 10:29out of his laboratory.
  • 10:30I might have been assigned to this day.
  • 10:33Oh wow, so that's that's
  • 10:34absolutely fascinating.
  • 10:35So so during your undergraduate years,
  • 10:37you were you were writing, and I didn't
  • 10:40write so much under my eyes.
  • 10:42In my undergraduate years,
  • 10:43I started that more as when I
  • 10:46came back as a graduate student.
  • 10:48And wrote a column for the
  • 10:50Daily Californian's newspaper,
  • 10:51but then they would buy.
  • 10:53This is now in 1970 and.
  • 10:57Long before can skate and
  • 10:59a lot of other things,
  • 11:00there was actually shootings
  • 11:01in tear gas constantly.
  • 11:03At Berkeley.
  • 11:03It was a very,
  • 11:05very disruptive from from
  • 11:062 control of the protests.
  • 11:07Or, yeah, yeah, absolutely yeah.
  • 11:09This is a part of history
  • 11:11that I don't know very well,
  • 11:13so this is absolutely fascinating for
  • 11:15me. Yeah, I wanted we could go off on that,
  • 11:18but it's yeah, it was.
  • 11:20There were so good science and good
  • 11:22teaching and smart people there.
  • 11:23Obviously it's a world class
  • 11:25University and but I think that.
  • 11:27In retrospect, the politics were
  • 11:29so dominant that I got less out
  • 11:32of the experience of being there
  • 11:34that I could have if it were,
  • 11:37say, yeah, or
  • 11:38someplace else. What was it like
  • 11:40working at a scientific lab?
  • 11:42You know, a science lab.
  • 11:44During a moment when there was a
  • 11:46heavy anti science sentiment in
  • 11:49your generation. I don't remember that my
  • 11:51generation had anti science sentiment.
  • 11:53The environmental movement was
  • 11:55just beginning and I I had never.
  • 11:58Seen as anti science and you talk
  • 12:00about anti science now in terms of the
  • 12:04regulations that the Trump administration
  • 12:06is trying to illuminate. But I don't.
  • 12:09I don't ever recall feeling and I any
  • 12:12anti science sentiment and I don't.
  • 12:15And Pew surveys now and things
  • 12:17got along for a long time.
  • 12:20In science, it held it enormous respect.
  • 12:22Still an
  • 12:23was then I guess I associate the
  • 12:25protests against the war and
  • 12:27against experimentation. Things like
  • 12:29that. Yeah, well,
  • 12:30the report is against the war for sure,
  • 12:33and I felt very strongly and myself,
  • 12:36and that it was an awful situation.
  • 12:38But it wasn't about science except in
  • 12:41very specific ways like making weapons.
  • 12:43But the scientific community
  • 12:45was growing enormously.
  • 12:46In those days and one of the first stories
  • 12:49I covered when I got to Science magazine
  • 12:52was the war on cancer that Richard Nixon was.
  • 12:56Forced to sign. He wasn't.
  • 12:58Nobody put a gun to his head,
  • 13:01but he was politically
  • 13:03very wealthy lobbyists.
  • 13:04Who spend all our time on health matters,
  • 13:07name Mary Lasker.
  • 13:08Put together this coalition of Democrats
  • 13:11and Republicans and and they didn't want
  • 13:13to hear about basic science they wanted.
  • 13:16Why isn't there a cure for cancer and used
  • 13:19and became known as the War on cancer even
  • 13:22though it wasn't officially called that?
  • 13:25But of course whenever you declare war
  • 13:28on something that people start asking.
  • 13:30Or are we winning the war?
  • 13:32And that question goes on today?
  • 13:34Because the.
  • 13:36Numbers of.
  • 13:37Cancer deaths in the United
  • 13:40States especially are.
  • 13:42Despite all the miraculous sounding
  • 13:44things we hear about immunotherapy's
  • 13:47another and targeted therapies,
  • 13:48other treatments is vastly driven
  • 13:51by the amount of people smoke or
  • 13:54how many people are obese and
  • 13:56things environmental factors that
  • 13:58have nothing to do with treatment.
  • 14:03So. The decision for you did go
  • 14:06to Science magazine and become a
  • 14:08full time writer. Yeah, I was. I
  • 14:11was on the staff was very early announced.
  • 14:14Now it's a giant and very.
  • 14:16Very very good section
  • 14:18of of Science magazine.
  • 14:19But in those days just a few of us,
  • 14:22I think I was a third
  • 14:24higher reported on some of the biggest
  • 14:26science stories that have happened in
  • 14:28the last for more than my lifetime.
  • 14:31At least the last 30 four
  • 14:33years already I was.
  • 14:34I was at NBC for 38 years
  • 14:36an the I came there in nine.
  • 14:38I went to local news for six months in.
  • 14:421976, and then they sent me
  • 14:45to Washington for a year.
  • 14:48But I was always tagged to be the
  • 14:50science and medicine correspondent.
  • 14:52Was that on account of
  • 14:54your science, training or
  • 14:55person? Because of my size training,
  • 14:57they in the mid 70s there were
  • 14:59still only three networks,
  • 15:01which of course makes an enormous difference.
  • 15:03If you want to talk about televisions,
  • 15:06nothing like the media environment of today.
  • 15:08An enormous percentage of American
  • 15:10public sat down at 6:30 or 7:00
  • 15:13o'clock and watch the Evening
  • 15:14News on one of the three networks.
  • 15:17And that's why my voice was familiar to you.
  • 15:20Because you.
  • 15:20You heard it when you were growing up,
  • 15:23along with almost everybody was
  • 15:25on television and I remember a
  • 15:27colleague when I got the NBC
  • 15:28very beginning in my career.
  • 15:30He said you have to realize there
  • 15:32were fewer of us and he meant network
  • 15:34television correspondents for the
  • 15:35major news organizations here.
  • 15:37There's fewer of us than there
  • 15:39are members of the US Senate.
  • 15:42I never thought of that. Yeah, that's
  • 15:44fair, yeah, and he was so
  • 15:46we had a position and uh,
  • 15:48of authority and responsibility and I
  • 15:50hope we carried out the responsibility,
  • 15:52but it was nothing. And, you know,
  • 15:55get recognized on the street.
  • 15:56Then you know people like you reckon.
  • 15:59Remember, my voice is for
  • 16:00very heartening experience,
  • 16:01so I had a touch of celebrity
  • 16:04without any of the burdens of it.
  • 16:06I was never.
  • 16:07That's pretty ideal I guess. Yeah, right,
  • 16:09because it was. It's
  • 16:11interesting. Because the.
  • 16:15I almost never had anybody complained
  • 16:17to me about stories when they recognize
  • 16:19me and I would get recognized a lot.
  • 16:21And usually people wouldn't bother
  • 16:22me with them when they did,
  • 16:24it was just complementary.
  • 16:26They say they enjoyed this story
  • 16:28about this or that I remember.
  • 16:30Speaking to Michael Kinsley,
  • 16:31who was an editor at the
  • 16:33time at the New Republic,
  • 16:34where I occasionally wrote articles,
  • 16:35and he was on Crossfire with Pat Buchanan,
  • 16:38and he said, everybody came up to him,
  • 16:40and they wanted to finish the argument.
  • 16:42So if you're on,
  • 16:43and that would be just the beginning
  • 16:45of that kind of television where
  • 16:47people scream at each other,
  • 16:49we didn't do that, we told,
  • 16:51told a story,
  • 16:51and a certain amount of time.
  • 16:53So it
  • 16:54occur to me that you know,
  • 16:56and I'm sure this is delivered on
  • 16:57account of your the medium, that you're.
  • 17:00Reporting on, but your story is.
  • 17:03Almost invariably presented a
  • 17:05scientific topic like some science
  • 17:07concept very clearly very simply,
  • 17:08but they also had a almost a case study,
  • 17:11like a person involved,
  • 17:13and so it's like you're
  • 17:15presenting the concept and then
  • 17:16the application of the concept.
  • 17:18In the real world,
  • 17:20an was at a common formula.
  • 17:22Yeah, it was a very standard form,
  • 17:24formulaic thing,
  • 17:25and sometimes occasion there
  • 17:26would be the occasional scandal.
  • 17:28Or is the thing that things that
  • 17:31didn't workout as as you plan,
  • 17:33but for the most part.
  • 17:35If you're telling a story
  • 17:37about a medical advance,
  • 17:38you have to have a human being in it,
  • 17:41and I think that sometimes you
  • 17:42can convey the wrong impression
  • 17:44because you want to have the more
  • 17:46attractive human being in it.
  • 17:47And like, for instance,
  • 17:49if you're doing a story about cancer
  • 17:51that that was one of the questions
  • 17:53I always ask my students is what's
  • 17:55the biggest risk factor for cancer.
  • 17:57And of course,
  • 17:58people say chemicals or cigarettes
  • 17:59is the most common answer,
  • 18:01but of course it's age.
  • 18:04Only one
  • 18:05one out of eight women will
  • 18:07develop breast cancer. Yeah,
  • 18:08but most of them will develop in
  • 18:10their 60s and 70s and then add
  • 18:13it as since that's my cohort,
  • 18:15I'm not eager for it to happen, but I'm just.
  • 18:18But there are about 12,000 cases of
  • 18:21pediatric cancer in the United States.
  • 18:23Deaths from pediatric cancer in
  • 18:25the United States every year,
  • 18:26which each one is a horrible tragedy.
  • 18:29But there's 600,000 deaths from adult cancer,
  • 18:31so you have to look at that.
  • 18:34As a proportion of
  • 18:36the so you you knew you know the
  • 18:39fundamentals of the field and immunology,
  • 18:42and then you found yourself in the 80s
  • 18:45and 90s reporting on the AIDS crisis.
  • 18:48So how what was that like and how did
  • 18:51you interact with the communities on the
  • 18:54cyantific and the policy and the well?
  • 18:57I was one of the first people there and
  • 19:01that was so is very
  • 19:04welcomed because they were.
  • 19:06Languishing in lack of adversity
  • 19:08and the lack of publicity was
  • 19:10at the beginning was not just
  • 19:12because of the Ronald Reagan,
  • 19:14famously not saying the
  • 19:16word aids for many years,
  • 19:18and the government not being
  • 19:20interested in disease.
  • 19:21It very quickly was seem to
  • 19:23be just affecting stigmatized
  • 19:25groups and then poor countries,
  • 19:27mostly in Sub Saharan Africa.
  • 19:29But throughout the world there was
  • 19:31also a lot of resistance in the gay
  • 19:34community to talking about it at
  • 19:37first because they didn't want it.
  • 19:39They thought it would bring on more stigma,
  • 19:43but it only been since the stone
  • 19:46Stonewall riots in 1969 that there had
  • 19:49been a gay liberation movement an in.
  • 19:5219 was very recently I have
  • 19:54to look this up with Lawrence
  • 19:56versus Texas was in the 1980s,
  • 19:57which is a Supreme Court case that said that.
  • 20:00Anti sodomy laws were unconstitutional.
  • 20:02I think was
  • 20:03more recent than that. Yeah is
  • 20:05very very recent.
  • 20:06Yeah so a lot of you know a lot of
  • 20:09states homosexuality was illegal right?
  • 20:11And so they didn't want people
  • 20:13coming in and asking them about it.
  • 20:15So it was. It was, uh,
  • 20:18I mean I quickly made friends
  • 20:21and Anne was able to.
  • 20:23Do and I mean my my greatest regret
  • 20:25is I didn't do more about HIV aids
  • 20:28even though I got a lot of credit
  • 20:30for what I did do because I also
  • 20:32at the same time was covering the
  • 20:34space Shuttle artificial hearts.
  • 20:38Rollins of Cancer and you know there was
  • 20:40there was constantly constant stories
  • 20:41and you just mentioned BF Skinner,
  • 20:43which I'd completely forgotten about.
  • 20:45Yeah, that was also during the
  • 20:46day when he was just starting
  • 20:48up. He was just just the breath
  • 20:50of the stories that you covered.
  • 20:52Like all of the big topics,
  • 20:53all the big topics.
  • 20:55You were there, right?
  • 20:57I was enormously blessed by that
  • 21:00because of that I've had this huge
  • 21:02amount of you to wake up in the
  • 21:04morning and always do something
  • 21:06that you can think is interesting.
  • 21:08For the most part.
  • 21:09Obviously it doesn't always
  • 21:11work out well, so how does
  • 21:13that work practically for
  • 21:14you? Well, a lot of those.
  • 21:16A lot of the reporting was based on
  • 21:18what was coming out in the journals.
  • 21:21Is journals probably too large in extent
  • 21:23and I think see now the major publications
  • 21:26are backing off from just covering.
  • 21:28You know what's new in Journal or JAMA or.
  • 21:32Science or nature disk.
  • 21:35The size is important.
  • 21:38The but will you know if people know this?
  • 21:43Press releases are given up in an
  • 21:45embargoed fashion a few days in advance
  • 21:48so that scientists can excuse me so
  • 21:50the reporters can get a chance to get
  • 21:52up to speed on the story before they
  • 21:54have to write it or broadcast it.
  • 21:56But that also has the effect
  • 21:58of at 2:00 PM on Thursday.
  • 22:00If a story, say in science,
  • 22:02it'll come out on every broadcast
  • 22:04and print medium,
  • 22:04and as a result it looks like it's news.
  • 22:07But of course anybody in the field
  • 22:09will have heard about this is a
  • 22:11conference and talking like sponsor,
  • 22:13yeah, but
  • 22:13it's been going on for a long
  • 22:16time, but this is when it
  • 22:17becomes official. News.
  • 22:19So how do you? How do you manage that?
  • 22:23So I just want to return to the AIDS crisis.
  • 22:26So, so here you're you're reading
  • 22:29reports of the death toll rising,
  • 22:31or maybe giving those reports yourself,
  • 22:33sure, and how? How do you know?
  • 22:37Where to go after that?
  • 22:39Like how do you find?
  • 22:40How do you find groups to speak with?
  • 22:43How do you select what scientists to go and
  • 22:45speak with? Well, it was.
  • 22:47It was pretty obvious that there were
  • 22:49there weren't that many scientists in the.
  • 22:52In the field, who really cared about
  • 22:55it so he wasn't hard or doctors
  • 22:58under the one of you in the building
  • 23:01where we're doing this podcast?
  • 23:04As I just saw Jerry Friedlander,
  • 23:06who is a hero of HIV, AIDS,
  • 23:09and I started interviewing him in the 1980s.
  • 23:12He was in the Bronx when there
  • 23:15was this horrible epidemic among
  • 23:17Ivy drug users and their spouses,
  • 23:20an children, an he since done
  • 23:22marvelous work in South Africa with.
  • 23:25HIV, AIDS and tuberculosis,
  • 23:26and he continues.
  • 23:27I mean, she's here today.
  • 23:29Usually he's in South Africa,
  • 23:31so he was here and they're like, yeah,
  • 23:34they just signed who just saw a
  • 23:38few minutes ago? Turnovers. Yeah,
  • 23:42so you're going all over the US all over
  • 23:45the world warning world.
  • 23:47Yeah, I was sure I would.
  • 23:49NBC was very good about that.
  • 23:51Sending me to Africa and going at the
  • 23:54beginning going to Haiti 1st and then
  • 23:56Africa was very tough because they
  • 23:59everybody didn't want to be blamed
  • 24:01for this disease and they it was.
  • 24:04It was highly stigmatized as well.
  • 24:06What do you mean like the
  • 24:08government or anything?
  • 24:09The government certainly ANAN,
  • 24:11but finally it would. In our first.
  • 24:15What when I first went to Haiti?
  • 24:17Which you know this thing came up where.
  • 24:22Doctors were seeing people mostly in
  • 24:25New York and in Miami, who were Haitians?
  • 24:28What originally was?
  • 24:29It was gaming and drug users an.
  • 24:34And there was no,
  • 24:35they didn't have any risk factors.
  • 24:37Nobody knew that there was a massive
  • 24:40epidemic going in Haiti at the time,
  • 24:42but I went to Haiti and was
  • 24:44followed around by the secret
  • 24:45police and nobody would talk to me.
  • 24:48But of course I could talk to
  • 24:50Haitian doctors in the United States.
  • 24:52But there was enormous discrimination
  • 24:53against station.
  • 24:54So I did a piece in 1983 where
  • 24:56we had Haitian saying that they
  • 24:58were fired just because they were
  • 25:00Haitians and families were afraid
  • 25:02that they would get AIDS from.
  • 25:04They were fired in the US because reasons.
  • 25:09Well, so that's an aspect of
  • 25:11medicine that we're only starting
  • 25:13as physicians to talk about.
  • 25:15You know, the stigma and the social factors.
  • 25:18Like in psychiatry we have this
  • 25:20biopsychosocial model where for
  • 25:22every patient we have to try to
  • 25:24consider the social situation.
  • 25:25And so you were reporting on a lot of this
  • 25:29in from a medical perspective, right?
  • 25:31'cause this is what it was,
  • 25:34a medical, introspective and one of
  • 25:36the things I went to San Francisco
  • 25:40a lot to do the reporting an.
  • 25:43And I wasn't the only Reporter who
  • 25:45did that for the domestic reporting
  • 25:47on the emerging azik epidemic.
  • 25:49And the reason was San Francisco
  • 25:52had a large gay community of young
  • 25:54men who had recently come out,
  • 25:57and they were very politically powerful.
  • 25:59There was, they had 70,000 registered
  • 26:01voters in a city of 600,000,
  • 26:03so they were a considerable political force.
  • 26:06And as a result,
  • 26:08they weren't as afraid an to
  • 26:10be open and talk.
  • 26:12And then San Francisco General
  • 26:14opened its dedicated AIDS units,
  • 26:16the inpatient and outpatient in 1983.
  • 26:18And so we go even go in there.
  • 26:22If I there were big institutions in New York,
  • 26:26want some of which refused to
  • 26:28treat people with HIV AIDS,
  • 26:30which then you can argue about all the
  • 26:34ethics of that others like Bellevue,
  • 26:36which were just completely overrun the.
  • 26:41People who did their residencies,
  • 26:43especially in internal medicine,
  • 26:44but it almost anything and in the
  • 26:4780s through the discovery of the good
  • 26:50drugs in the mid 90s at Bellevue,
  • 26:52which is a great residency,
  • 26:54much sought after.
  • 26:57So almost nothing but AIDS,
  • 26:59so they were doing things like treating
  • 27:01these rare opportunistic infections
  • 27:02which in most situations you would
  • 27:04never see an American medical practice.
  • 27:06And as a whole they treated well.
  • 27:09How did I let me finish on something?
  • 27:12So a lot of these hospitals and I would
  • 27:15not let camera crews in because they
  • 27:17did not want the ones that did treat it.
  • 27:20People with aids?
  • 27:21They didn't.
  • 27:22They wouldn't let you in there because
  • 27:24they didn't want their other patients
  • 27:27to know that they were raised.
  • 27:29And in the war, oh.
  • 27:31So they didn't.
  • 27:32We couldn't take a TV crew in
  • 27:34just most hospitals.
  • 27:36So you couldn't show people
  • 27:38with the situation was
  • 27:39like yeah, but you couldn't.
  • 27:40San Francisco and I did sometimes
  • 27:42in New York we there were certain
  • 27:44places like Albert Einstein was much
  • 27:46more open about it than other places,
  • 27:48but most most places would not
  • 27:50let it TV anywhere near or
  • 27:52whether people talk about it.
  • 27:53Talk about it.
  • 27:54I mean they would show up at conferences
  • 27:56and you could interview them there,
  • 27:58but not in the context of their hospital.
  • 28:02So I when I rotated through an
  • 28:05infectious disease, units just as
  • 28:07part of my medical internship,
  • 28:09some of my attendings were either Chinese
  • 28:12or already attendings during that period
  • 28:14and asking them questions about this crisis.
  • 28:17And you know how the public dealt with it,
  • 28:21how the government of the FDA
  • 28:23dealt with it on the NHS with it?
  • 28:27It's a very emotionally charged
  • 28:29still even you know, 35 years later.
  • 28:33Situation, so I'm curious how.
  • 28:36How you navigated those emotions
  • 28:38for yourself, like how you managed
  • 28:41reporting on something so emotionally
  • 28:43provocative and well, it was.
  • 28:45It was an
  • 28:46after a while. My biggest fight with
  • 28:49this was to get stories on the air,
  • 28:52because when it became there
  • 28:54were these big periods in the
  • 28:57history of the AIDS epidemic.
  • 28:59HIV AIDS epidemic.
  • 29:00One is when Rock Hudson got sick and
  • 29:04suddenly this gorgeous leading man.
  • 29:07Why did so? Nobody knew he was gay and
  • 29:09Magic Johnson in 1991 and other celebrities.
  • 29:12So these you can see big spikes and
  • 29:15interest in a disease at those times.
  • 29:17But for the most part,
  • 29:19especially especially before Rock Hudson,
  • 29:20it was there wasn't as much interest
  • 29:23in it as I would have liked.
  • 29:25I would keep coming back and trying to
  • 29:28do stories and producers would say no,
  • 29:30you know, go do a story on breast
  • 29:33cancer or go do a story about.
  • 29:36Chronic fatigue syndrome or something like
  • 29:38that? Kind of critique central enough, right?
  • 29:42What was their logic? Just they wanted
  • 29:45more diverse. Well, they want people
  • 29:47to watch the TV and the man putting on
  • 29:50pictures of men who have sex with men or.
  • 29:55People who inject drugs does
  • 29:57not attract the audience that
  • 29:58the television network wants.
  • 30:01Interesting, well at the same time though,
  • 30:04the presence of publicity.
  • 30:07And and you know,
  • 30:08obviously I'm talking as someone
  • 30:09who wasn't there and you know,
  • 30:11I'm obviously not a scholar of this moment,
  • 30:13but. Having the publicity allowed the
  • 30:16science to catch up to the epidemic
  • 30:19and allowed these politically active
  • 30:21groups to be able to help sculpt policy.
  • 30:24And so it was
  • 30:25a great article. By Alan Brandt who's
  • 30:30a historian of medicine at Harvard.
  • 30:32It was in the New England Journal of Medicine
  • 30:35called How Aids created Global Health,
  • 30:38and I highly recommend that
  • 30:40you or your listeners check out
  • 30:43that that article because.
  • 30:46Many things that we take for granted today,
  • 30:48such as patient activism,
  • 30:50an the need to think about other
  • 30:52people in a cooperative way and not.
  • 30:57Not necessarily a condescending way which
  • 30:59a lot of international health before the
  • 31:02HIV epidemic was very condescending.
  • 31:04You know we are donors would
  • 31:06give with what they would give
  • 31:08and it was preceded by a period.
  • 31:11There was even worse which was
  • 31:13Tropical Medicine where we would.
  • 31:15You're protecting our own people
  • 31:17or our troops or whatever.
  • 31:19So that has to do with the
  • 31:21history of public health. But the.
  • 31:25AIDS made everything different.
  • 31:26Was very clear that there
  • 31:28was this massive epidemic,
  • 31:29an one of the.
  • 31:31And it it's and there's a lot of
  • 31:34fear right now that there's going
  • 31:37to be a second wave of of because
  • 31:41there's 23.3 million people on
  • 31:43antiretroviral drugs in the world
  • 31:45was an astounding achievement,
  • 31:47and the.
  • 31:50If and Trump has reauthorized the
  • 31:52Trump administration is reauthorized,
  • 31:54PEPFAR, which is the major
  • 31:56contributor for those bills.
  • 31:57There are other donors as well,
  • 32:00but the biggest chunk of that
  • 32:02comes from the US government,
  • 32:04and he proposes cutting into
  • 32:06budget for it every year.
  • 32:08An you people here in the Yale
  • 32:10School of Public Health and others
  • 32:12have done calculations you can do
  • 32:14just very cold calculations for
  • 32:16every $1,000,000 that gets cut back.
  • 32:19How many million people are going to die?
  • 32:22Because there?
  • 32:23There's no cure,
  • 32:24and as a result there's all these
  • 32:26people that are going to die
  • 32:27if they don't get their drugs.
  • 32:30So that's the intersection of
  • 32:31advocacy and policy. Then write an
  • 32:33in that that came about them into.
  • 32:36Don't forget the. Larry Kramer,
  • 32:38who I become I became very close
  • 32:40to the famous AIDS activist who
  • 32:43started the gay men's health crisis,
  • 32:45first as a support group in
  • 32:471981 and he started out.
  • 32:50Screaming and yelling at there was this
  • 32:52horrible thing going on and he was.
  • 32:54He had enormous pushback from other members
  • 32:57of the gay community that he was approved.
  • 32:59He wanted to close down the bath
  • 33:02houses that places where men went
  • 33:04to have ****** and that was a huge
  • 33:06part of the early years was fight
  • 33:09within the gay community over whether
  • 33:11to close down the bath houses and
  • 33:13Kramer then got tired of the just the
  • 33:17advocacy and he started acting up.
  • 33:20An act up accomplished a lot of
  • 33:22called attention to a lot of things,
  • 33:25but then act up spun off yet another group
  • 33:27called the Treatment Action Coalition,
  • 33:30which exists to this day and
  • 33:32as marvelous work,
  • 33:33because what they did was they learn
  • 33:35they became as knowledgeable about
  • 33:37the disease as many of the scientists,
  • 33:39so they thought and it was a big,
  • 33:42big fight to get a seat at the
  • 33:45table on FDA and NIH review panels.
  • 33:48And but they got it.
  • 33:50And it made a big difference,
  • 33:52and now it's standard procedure.
  • 33:53This consumer representatives and
  • 33:55all those things. But it didn't.
  • 33:57It wasn't always that way.
  • 33:58And then the even people who were
  • 34:00working full time on the problem at the
  • 34:03NIH were disgusted at the idea none.
  • 34:05Now that they were homophobic,
  • 34:07but that non scientists would
  • 34:09come into the room.
  • 34:10But if you talk to some of these non
  • 34:13scientists they actually had this,
  • 34:14you know there's.
  • 34:17Cat's encyclopedic knowledge.
  • 34:18That's
  • 34:19so I'm turning around my head
  • 34:21around this as as you know,
  • 34:23someone that knows a little
  • 34:25bit about the science but very
  • 34:28little about the you know,
  • 34:30the the advocacy component,
  • 34:31and so these people have got together
  • 34:34and act up an they engaged media.
  • 34:37They staged protests, Anaza results.
  • 34:39They were able to curb the public opinion,
  • 34:42which then also changed the way
  • 34:44science functions, right?
  • 34:46And there were.
  • 34:47Yes, because one of the big questions.
  • 34:51Which goes back to what I was.
  • 34:54I had mentioned Mary Lasker, Mary Lasker's,
  • 34:56and the 1971 War on Cancer was
  • 34:59based on the notion that we don't.
  • 35:01We can't just sit around
  • 35:03and wait for basic research.
  • 35:05We have to have targeted research and
  • 35:07that's huge policy argument about
  • 35:09where it where does work come from.
  • 35:12But but.
  • 35:14At some point you have to say that we
  • 35:16have this massive public health problem.
  • 35:19We have to just worry about
  • 35:21this and think about things that
  • 35:23will make a difference in this.
  • 35:25Anne Marie lost,
  • 35:26we wanted to do that with cancer and
  • 35:29it turned out it was way too early.
  • 35:31Nobody even when in 1971 nobody
  • 35:33even knew
  • 35:34what caused cancer. I mean it was
  • 35:37not. Uncle genes were not discovered.
  • 35:39They weren't discovered until 1976 in
  • 35:41chickens and then in 1981 and human beings.
  • 35:43So that was a lot of.
  • 35:46Time passed and everybody the money
  • 35:48it was was money and it did support
  • 35:51basic research that led to those
  • 35:53discoveries which are just now
  • 35:55starting to lead to drugs and well
  • 35:57the precision medicine you know.
  • 35:59Oncology is the poster child of precision
  • 36:01medicine nowadays right? Also the actual
  • 36:03numbers of people who get help or
  • 36:05are much lower than you would think
  • 36:08about because one of the difficulties
  • 36:10about doing a story about something
  • 36:12like a new immunotherapy for cancer
  • 36:15is you find somebody who was.
  • 36:17Almost dead yesterday and is now
  • 36:19is running the marathon and yeah,
  • 36:21but it turns out that only 12% of
  • 36:24people who get immunotherapy's
  • 36:26overall show any kind of response
  • 36:28that I'm talking about not talking
  • 36:30about surviving for years.
  • 36:32I'm just any kind of response,
  • 36:34let alone people who were.
  • 36:38What you would call a cure it
  • 36:40if you have go for several years
  • 36:42without recurrence? Well, so
  • 36:43how do you view so one of the
  • 36:46things I've observed is that.
  • 36:49More specifically in in psychiatry,
  • 36:50my field every five to 10 years.
  • 36:53Someone writes this paper that
  • 36:55we are about to enter the
  • 36:57Golden age of psychiatry, right?
  • 36:59See a lot of Golden Age is
  • 37:01a lot of goals, and
  • 37:03then you see it in every field of medicine
  • 37:06is a world where about we're about there,
  • 37:09I mean, and it's absolutely fascinating.
  • 37:12About how long things can take Francis
  • 37:15Collins, who's now the director of
  • 37:18the National Institutes of Health?
  • 37:21As head of the Human Genome Project
  • 37:23discovered, the gene for cystic
  • 37:25fibrosis in I have to look it up.
  • 37:27I don't have it.
  • 37:29I thought I had, but it was,
  • 37:31I think in the 1980s,
  • 37:33before the Genome project.
  • 37:34Yeah before long because yeah,
  • 37:36in the days when it took forever,
  • 37:38but it was just this last week
  • 37:40that the FDA approved a gene
  • 37:42based drug for cystic fibrosis.
  • 37:44That seems to be truly effective.
  • 37:46Oh, I
  • 37:47hadn't heard of that.
  • 37:50King, about decades between you and it
  • 37:52looks so exciting when you and it's true,
  • 37:55it was exciting to know that there
  • 37:57was this gene. But at the time,
  • 37:59kids with cystic fibrosis were
  • 38:01living there be 6 or 7 you know.
  • 38:03Now you have 40 and 50 year olds and
  • 38:05it looks like they may soon have a
  • 38:08completely normal life expectancy. So
  • 38:10so this perennial question of the Golden Age.
  • 38:13This is something that really
  • 38:14fascinates me and I spend time
  • 38:17agonizing over because a lot of it is,
  • 38:19you know, science is based on this.
  • 38:21Idea of of grants right?
  • 38:22If you want to be an academic scientist,
  • 38:24you write a grant for five years, right?
  • 38:26And you say I'm going to do this.
  • 38:28That and the other an at the
  • 38:29end of five years, you know.
  • 38:32Reflective scientists will be like did
  • 38:35I actually accomplish those things and
  • 38:37something that you know in your book
  • 38:39is how after there is this increased
  • 38:42funding for breast cancer or the NCI,
  • 38:44the National Cancer Institute had
  • 38:46their budget tripled or doubled.
  • 38:48His order order of magnitude all of a sudden.
  • 38:51All these scientists who were basic
  • 38:54scientists began to be interested
  • 38:55in a few sentences.
  • 38:57At the end of their granite
  • 38:59studying cancer right right?
  • 39:01And
  • 39:01you can do it, yeah?
  • 39:03Is pretty easy as you know,
  • 39:05as a scientist that to write those words in,
  • 39:09because almost any basic science
  • 39:11can be said to be relevant to the
  • 39:14cancer problem because the cancer
  • 39:16problem is how cells work, right?
  • 39:18Yes, how does the body where? How does the
  • 39:22body work and therefore you can
  • 39:24make it an it's interesting,
  • 39:26the immuno therapy stuff came
  • 39:28from 2 lines of research.
  • 39:30One was just really basic
  • 39:33research immunology and mice.
  • 39:35By James Allison.
  • 39:36When when he was at Berkeley,
  • 39:38now he's at MD Anderson an the
  • 39:41the other came from a discovery.
  • 39:45That was made very, very applied.
  • 39:47An HIV discovery that when the HIV
  • 39:50attacks the type of word but white
  • 39:53blood cells called CD four cells.
  • 39:55It doesn't just attach to
  • 39:5711 protein on the surface,
  • 39:59it attached.
  • 40:00To a coreceptor an there was a
  • 40:04study of sex workers female sex
  • 40:07workers in Nairobi which found that.
  • 40:12A very small percentage less
  • 40:14than one by far of them,
  • 40:16had unprotected sex with thousands
  • 40:18of men who were infected and it
  • 40:21never got the diseases themselves.
  • 40:22And it turned out that they had
  • 40:25a defect in this coreceptor Ann.
  • 40:27This is the Co receptor that makes up
  • 40:30what the basis for immunotherapy for cancer.
  • 40:33Now we have these two 2
  • 40:35lines of research that say
  • 40:37you never know, right?
  • 40:38Yeah, exactly unknown unknown.
  • 40:40Yeah you were working
  • 40:41with mice in a lab about.
  • 40:44Immunology is is one thing and but also
  • 40:47studying Kenyan sex workers is another.
  • 40:49Another thing is why is he why
  • 40:51somebody bothering to do this?
  • 40:53Well it turns out that you know
  • 40:55in the world one human being,
  • 40:57the Berlin patient has been cured
  • 40:59of HIV and it was because he
  • 41:01got a transplant from somebody
  • 41:03who had this defective receptor
  • 41:05as a treatment for leukemia.
  • 41:07So he is now cured of HIV.
  • 41:10Kind of incidentally yeah I saw
  • 41:12that but unfortunately it's
  • 41:13not something you want to.
  • 41:15Do is routinely, for you know,
  • 41:17the 35 million people in the
  • 41:19world who are moving with
  • 41:21HIV, but my head well.
  • 41:23So yes, I I fully.
  • 41:25I fully accept that.
  • 41:27You know serendipity is
  • 41:28a large part of science.
  • 41:30And embracing these serendipitous
  • 41:32discoveries often leads to.
  • 41:35Wonderful things like the unknown unknown.
  • 41:37So yeah, there's a lot of potential there.
  • 41:41However, one of the things that
  • 41:43makes me anxious is the selling of
  • 41:46science in a way that isn't completely
  • 41:49driven by the science itself.
  • 41:51O for example,
  • 41:53the the idea of selling your work is
  • 41:56being curated for a specific disease
  • 41:58when it's not directly related.
  • 42:01You know there is some salesmanship
  • 42:04in grantsmanship.
  • 42:05And you know, in order to get funded,
  • 42:07you have to get people excited.
  • 42:09However, this Golden age question.
  • 42:15Sorry, go ahead
  • 42:16and now the goal it well.
  • 42:18One of the things that happens if you talk
  • 42:21about there are lobbyists in Washington
  • 42:22who work on behalf of organizations
  • 42:24like the American Association for the
  • 42:27Advancement of Science or the American
  • 42:29Association of Universities. Anne.
  • 42:32The way that they have ways of doing it,
  • 42:35which is they tie it all it gets
  • 42:38tide up with other social service
  • 42:40programs and as a result it lifts the
  • 42:43tide and then then then scientists.
  • 42:46Add places like the NIH or the National
  • 42:49Science Foundation can make the decision
  • 42:51about what where the money should go,
  • 42:54and it doesn't just go to silly
  • 42:57projects that are designed to try to
  • 43:00cure diseases kind of offbeat way,
  • 43:02but a lot of stuff.
  • 43:06As you know, does get published.
  • 43:08It never gets replicated,
  • 43:09replicated or reproduced or refer to
  • 43:11and just goes off in the deep end,
  • 43:14and there's a lot of concern about that
  • 43:17and exactly how you steer this gigantic
  • 43:19ship and the scientific enterprise is
  • 43:22just growing so rapidly it if you look
  • 43:24at the charts of the number of journals,
  • 43:27the number of people working in
  • 43:29science and everything else.
  • 43:30So any argument that we're in an age
  • 43:33that's not a Golden age where we are.
  • 43:36Where the public doesn't support size.
  • 43:37I don't buy into that,
  • 43:38only we have we
  • 43:39have. So you think
  • 43:40this is the Golden age thing?
  • 43:42Yeah, we're definitely the
  • 43:43goal of the things that.
  • 43:45I hear about that are going on on this
  • 43:47campus and others and other institutes
  • 43:50around the country are just astounding
  • 43:52because the tools are getting so much better.
  • 43:55The Genome Project is the obvious one.
  • 43:57You know. It used to take months and months.
  • 44:00I mean I remember. The.
  • 44:05There aren't very many single.
  • 44:07Based as you know, the single gene disease
  • 44:11is caused by a defect in one gene or mute.
  • 44:14An alteration in one gene,
  • 44:16but the first one that we discovered
  • 44:19was Huntington's disease,
  • 44:20which was in 1984.
  • 44:23And it took them until 1994 to
  • 44:25actually sequence that gene because
  • 44:27the technology was so crude.
  • 44:29Now. Now if somebody knew
  • 44:30the location of that gene,
  • 44:32they could hear it, Yale,
  • 44:33it would put it outside.
  • 44:35They could do it in a much even faster way,
  • 44:38but usually what they do is they put it
  • 44:41outside their door in a bucket like you
  • 44:43see outside of your doctors office for
  • 44:45blood and urine samples is picked up.
  • 44:48It's taken to a gene sequencing and they get
  • 44:51it back in the morning on their computer.
  • 44:53And they can compare it to every
  • 44:56known gene sequence in every
  • 44:58animal creature on Earth an.
  • 45:01At best,
  • 45:01pretty Golden age. Yeah,
  • 45:02that's pretty Golden age and and
  • 45:04what's happening now is one
  • 45:06of the biggest problems is
  • 45:07there's so much data coming in.
  • 45:09How do you deal with all the data?
  • 45:11There's so much information? Well,
  • 45:12what are your thoughts on neuroscience then?
  • 45:14Like how do you view that?
  • 45:16Our understanding of the brain in relation
  • 45:18to these? Otherwise I think we have a
  • 45:21long way to go and understanding science.
  • 45:23What makes. It is very interesting if you.
  • 45:27Think about evolution and Richard Dawkins
  • 45:31who's one of my favorite writers of
  • 45:35all these brilliant actually written.
  • 45:38He but. And he he gets pounced on
  • 45:41all the time by the religious right,
  • 45:44because of he thinks that religion is a
  • 45:47meme term that he invented, but it's.
  • 45:50But it's a meme is a conscious thing.
  • 45:53It's not a gene and he and he
  • 45:55constantly says that we've developed a
  • 45:57consciousness we because we have a brain.
  • 46:00It came from evolution.
  • 46:02But we don't understand it.
  • 46:03We don't have the mechanism
  • 46:05to understand our own brains.
  • 46:07And as an example of why everything is
  • 46:09not driven by Darwinian natural selection,
  • 46:12he says, well, we wouldn't have.
  • 46:15Option one practice contraception
  • 46:16if we wanted to just increase our
  • 46:19our genes in the world.
  • 46:20Well so so I think his
  • 46:22arguments pretty sound though.
  • 46:23So like why would we suppose that our
  • 46:26brains evolved to understand the brain?
  • 46:28No, I don't think we have the
  • 46:30capacity to do that. So then.
  • 46:32So then what direction like in terms of
  • 46:34the Golden age of neuroscience then.
  • 46:36So so there have been many stories
  • 46:38purporting that this decade of the brain,
  • 46:41for example, right like you know,
  • 46:43we're going to devote a lot of money to this,
  • 46:46like we did with the.
  • 46:47Human genome and in 10 years will
  • 46:50shake her hand and what happened?
  • 46:52No, not much right.
  • 46:53There was a decade
  • 46:54of the brain. Sounds like a good idea
  • 46:57and I'm sure they pay for decent science.
  • 47:00I'm not up on the literature
  • 47:02on that. I don't know what to tell
  • 47:04ya to say that that we learned.
  • 47:07You know nothing is obviously false.
  • 47:09I mean we know wealth of information about
  • 47:11the brain, like how neurons function,
  • 47:13how they organized you, know sub circuits
  • 47:16and circuits and networks and systems.
  • 47:18Throughout the brain, but are we able to
  • 47:21bring that to the level of healthcare?
  • 47:24Not quite yet right?
  • 47:25And so that's the question then,
  • 47:28is like something that I've been musing over.
  • 47:31Is all of these movements.
  • 47:33I hope that I don't mean that in a
  • 47:37derogatory way to say like the AIDS.
  • 47:39Advocates were like a movement, but I don't.
  • 47:42I don't know another word to
  • 47:45describe that like that movement.
  • 47:47The cancer movement,
  • 47:48specifically the breast cancer movement.
  • 47:50These people were able to create a
  • 47:53lot of enthusiasm which then trickled
  • 47:56into the scientific enterprise
  • 47:58in the form of funding,
  • 48:01which then allows treatments to
  • 48:03eventually be brought to market.
  • 48:06Which one is lucky?
  • 48:08I mean,
  • 48:08there's feel like,
  • 48:10yeah, but it also allows the
  • 48:13scientific understanding.
  • 48:14Sometimes that doesn't wait to treatments.
  • 48:18And it's not a bad thing.
  • 48:19I mean, and there still is support
  • 48:22despite everything else for the.
  • 48:23Like the wonderful things that say,
  • 48:27Carl Zimmer writes about about the
  • 48:30interaction of a lichen and fungus and
  • 48:33sure or the which is terrifying. By the
  • 48:36way they are. Or or or
  • 48:40does this interest that we all have in in
  • 48:42the origin of human population migrations?
  • 48:45That's not going to. That probably is
  • 48:47not going to tell us anything that's
  • 48:49going to be useful in the clinic,
  • 48:51but I think it should be supported not
  • 48:53just because I like to read about it,
  • 48:56but I think, you know,
  • 48:57tells us more about who
  • 48:59we are and it's absolutely
  • 49:00fascinating. So any knowledge
  • 49:01is good knowledge, then yeah, well,
  • 49:03any yeah? Any knowledge that is not
  • 49:05used for destructive purposes as good
  • 49:07knowledge? Napalm? It's not
  • 49:08good. No, I don't think.
  • 49:10I don't think Napalm is good
  • 49:12under any circumstances,
  • 49:13and it goes for a lot of other other things.
  • 49:16But if you're thinking about.
  • 49:19The scientific enterprise.
  • 49:22Yeah, I get back to these Pew surveys.
  • 49:24Science has never been held in higher regard.
  • 49:27Let me people there are these awful
  • 49:30things that are going on like.
  • 49:33Cuts in environmental regulations
  • 49:35that are based on pseudoscience that,
  • 49:37but a lot of that is a political decision.
  • 49:40Are we willing to be like India and
  • 49:42China and breed really horrible air so
  • 49:45that some people can make more profits?
  • 49:48Or are we?
  • 49:50Those are political ideas and the
  • 49:53other the other thing that keeps
  • 49:56coming that I keep thinking about is.
  • 49:58This idea of the.
  • 50:01Global warming and climate change are so.
  • 50:05Threatening that are we wasting our time
  • 50:07thinking about almost anything else?
  • 50:09And there are people that make that argument.
  • 50:12Jonathan Franzen had a very good piece.
  • 50:14And then in The New Yorker a
  • 50:17few months ago about that,
  • 50:19that it's so hopeless that.
  • 50:21So we we we go on as if our children our
  • 50:24grandchildren are going to have decent lives.
  • 50:26Whenever I was talking about
  • 50:27the financial aspects of my
  • 50:29generation versus your generation,
  • 50:30but think about what it could be
  • 50:32like for our kids and our grandkids.
  • 50:34If if the world really goes to
  • 50:36hell in the way it seems to be in
  • 50:39a lot of people think it will be
  • 50:41because of reinforcing.
  • 50:43Feedbacks that are just getting worse and
  • 50:45worse and nobody is doing anything about
  • 50:48it at any kind of scale that it could.
  • 50:51Matter and so maybe you know you
  • 50:53thinking about the brain or me talking
  • 50:55about breast cancer activism for HIV,
  • 50:58AIDS, or even trying to illuminate.
  • 51:00And it's horrible.
  • 51:01Probably you know, tuberculosis or HIV,
  • 51:03aids and all these other terrible
  • 51:05global health problems.
  • 51:06But all that could be meaningless
  • 51:08in a big hurry if if climate change
  • 51:11gets so bad that there's no food
  • 51:14and there's a lack of water and all
  • 51:16that, well, so so this is again an area that.
  • 51:20You know you see the science, right?
  • 51:23The science is fairly clear and robust.
  • 51:25I mean, there are these models
  • 51:27that have been known for decades,
  • 51:29and there are advocacy groups
  • 51:31like there's a movement.
  • 51:32You know that it's getting
  • 51:34more popular with young
  • 51:36people, which is good. Which is good. But
  • 51:38so, like when, how do you
  • 51:40view a critical mass forming?
  • 51:42So at what point? I don't know. This
  • 51:45is not something that I've been involved in.
  • 51:48Sometimes I feel like I should be.
  • 51:51You know involved in it and you
  • 51:53see things like Jane Fonda getting
  • 51:55arrested every Friday along with
  • 51:57a bunch of other celebrities.
  • 52:00Now on the steps of the Capitol.
  • 52:02Maybe that will call attention to it,
  • 52:05but it's very hard to wrap your
  • 52:07head around how bad it is an
  • 52:10particularly because you've got just
  • 52:12become a religion to be against it.
  • 52:14For certain political parties.
  • 52:16So people are much more.
  • 52:20Aligned to disbelieve it even,
  • 52:21even though the evidence is stronger.
  • 52:23And also it's happening over a time
  • 52:26frame that we don't quite understand.
  • 52:28Have a new treatment for cystic
  • 52:30fibrosis or cancer comes along.
  • 52:32Yeah yesterday it wasn't here today
  • 52:34is here and we suddenly see it.
  • 52:36This is given
  • 52:37to patients better and in some way. But this
  • 52:40doesn't work that way. Anne.
  • 52:44It could be just awful an I I don't
  • 52:46know if there are people here an
  • 52:48elsewhere here yell and elsewhere who
  • 52:51work at the idea of communicating this.
  • 52:53You know, how do you tell people
  • 52:55this is such a serious problem
  • 52:57that we have to worry about it?
  • 52:59I remember even a few one of
  • 53:01the few times we were talking
  • 53:03bout good reactions to stories.
  • 53:05I did it with the one time
  • 53:07I got a lot of hate Mail.
  • 53:10And in those days it was just Mail.
  • 53:12It was an email or social
  • 53:14media when I did a story about.
  • 53:16Global warming,
  • 53:17one of the first stories when
  • 53:19I was starting to become more
  • 53:21public issue what year is that?
  • 53:23Oh, is in the 80s eighties.
  • 53:25Brian Johansson came out and but
  • 53:27it didn't phase and people can't.
  • 53:29You know, then,
  • 53:29when it's really hot on the East
  • 53:31Coast and everybody in Washington,
  • 53:33New York's miserable and or
  • 53:35there's a power outage.
  • 53:36Or there's a big hurricane.
  • 53:38Now people are starting to
  • 53:39accept the severe weather.
  • 53:41Is is part of global climate change and
  • 53:43that wasn't accepted for a long time.
  • 53:46Well, so so this is.
  • 53:48One of my editors at Scientific
  • 53:50American, Mike Lemonick,
  • 53:51who had interviewed for this podcast.
  • 53:54He and I had a discussion
  • 53:56about the impact of science
  • 53:58journalism on science policy,
  • 54:01and so I'm curious if you feel
  • 54:03like your journalism in AIDS and
  • 54:06cancer treatments and you covered
  • 54:08Alzheimer's and Human Genome project,
  • 54:10do you feel like that has had an
  • 54:13affect in sculpting policy? I
  • 54:16think not mine necessarily,
  • 54:18but overall it does.
  • 54:20I think that awareness does
  • 54:21help people appreciate where
  • 54:23their tax dollars are going,
  • 54:25but there and that's been part of perhaps
  • 54:28the reason that there was not a lot of.
  • 54:31Objection to it science is
  • 54:33always done pretty well.
  • 54:35I'd get has its ups and downs
  • 54:37and you mentioned before the
  • 54:39when the NIH doubled its budget,
  • 54:42which was a huge mistake that
  • 54:44was made during the Clinton Bill
  • 54:46Clinton administration, the.
  • 54:50They doubled the budget,
  • 54:51but then they didn't fall through,
  • 54:53so there's all these graduate students
  • 54:56and postdocs who suddenly given fell
  • 54:58off a Cliff like doubling the
  • 55:00enrollment in medical school without
  • 55:02doubling residency right exactly.
  • 55:03Yeah, it was a bad idea, yeah?
  • 55:06But then again, there's a big tendency to.
  • 55:09If somebody puts money on the
  • 55:11table to take it and not say
  • 55:14we're not going to take that.
  • 55:16But but those stories are satisfying.
  • 55:18I enjoy reading about.
  • 55:20Science or and I enjoy just like I
  • 55:23enjoy a good play or a movie that
  • 55:25has nothing to do with science.
  • 55:28It's part of the human experience
  • 55:29and I think that it makes people feel
  • 55:32satisfied to get good information.
  • 55:34Well, you certainly made
  • 55:36thousands of millions of people satisfied.
  • 55:38Flickering through the years and I guess
  • 55:41we're actually running a little low on time.
  • 55:43I don't want you to be late
  • 55:46for your new class, OK?
  • 55:49But we are OK. We are we OK?
  • 55:51Yeah, I think we have 5 minutes 5 minutes.
  • 55:54OK, I use magic that out about time,
  • 55:57but you know, just in the last
  • 55:59five minutes here I'm like what?
  • 56:01Where do you see science
  • 56:03journalism an going in the future?
  • 56:05I because I have this sense that science
  • 56:07is becoming more and more complex and
  • 56:09to be able to report about science,
  • 56:12you're going to have to become
  • 56:13more and more sophisticated.
  • 56:15Like for example, you you had a,
  • 56:17you know, a whole leg and not just a shoe.
  • 56:20Because you had a lot of scientific
  • 56:22training and so that gave you a springboard
  • 56:25into the world of science journalism.
  • 56:28So how do you feel the next generation
  • 56:30of science journalists are going
  • 56:32to feel very optimistic about it?
  • 56:34Because like the stuff that you do in
  • 56:37Scientific American and all the good
  • 56:39stuff that's in National Geographic sites,
  • 56:41and there, there is an enormous
  • 56:43amount of good information out there.
  • 56:45And there are certain percentage
  • 56:47of people who seek it.
  • 56:49The big problems are that a lot of
  • 56:51stuff gets trivialized, particularly.
  • 56:53Nutritional Epidemiology, you know,
  • 56:54I can promise you that they'll in
  • 56:57February there will be stories
  • 56:58that just before Valentine's Day
  • 57:00that chocolate is good for you.
  • 57:03Yeah this and wanted by Hershey.
  • 57:05Sponsored by you know somebody will
  • 57:07do is to study of 17 people and find
  • 57:10out that there's an antioxidant.
  • 57:12Chocolate of course you have to eat so
  • 57:15much of the chocolate you gain 10 pounds.
  • 57:19But the and those things are constant.
  • 57:27Uh, with evergreens,
  • 57:29they think they're constantly showing
  • 57:31up on the morning talk shows like
  • 57:33the Today Show and Good Morning
  • 57:36America and the CBS Morning show.
  • 57:38The people are all whole another.
  • 57:40John Oliver did a great spot on this on.
  • 57:45John Oliver did a very good spot
  • 57:48about science, journalism and.
  • 57:51It in the whole lot of stuff
  • 57:53gets blown on it, blown up.
  • 57:56Out of proportion.
  • 57:57And it's not just.
  • 58:01These small studies get a lot
  • 58:03of attention because they come
  • 58:05to a result that people want
  • 58:06to hear or it scares people or
  • 58:08whatever it takes to.
  • 58:09I love the wine study.
  • 58:11Yeah, one drink two to three
  • 58:13glasses of wine. Your heart.
  • 58:14Well yeah, right and under the
  • 58:16guise Sinclair it at Harvard,
  • 58:17David Sinclair has been fortunate
  • 58:19company to try supposedly distills
  • 58:21the antioxidant from red wine into a
  • 58:22pill that prevents you from aging.
  • 58:24So why would you ever want to take the
  • 58:27pill? And you can just drink the wine?
  • 58:29Yeah, exactly exactly. You have to drink.
  • 58:31Case of it together, but alright here.
  • 58:33Let's say in an afternoon. But
  • 58:37but the as I clear that that's going to work.
  • 58:40The problem is that that part of the
  • 58:42scientific process is not as getting better.
  • 58:45Major publications like the New
  • 58:47York Times and Washington Post,
  • 58:49and I think to a certain extent
  • 58:51the networks in their coverage
  • 58:53have done less of that dude.
  • 58:55Taking small studies and they can
  • 58:57go for a whole lot of reasons,
  • 58:59go either way and making
  • 59:01a big deal out of it.
  • 59:06But there is a lot of lack of
  • 59:08understanding of the need for.
  • 59:12This consistent beta the data coming to
  • 59:14the same conclusion before you make it
  • 59:16recommendation and a lot of things changed.
  • 59:19I mean it was a really big deal in the
  • 59:211990s when the Women's Health Initiative
  • 59:23showed that hormone replacement
  • 59:25therapy was not was more harmful than
  • 59:28beneficial and millions of women
  • 59:29there went off it in an afternoon and
  • 59:31suffered severe consequences like hot
  • 59:33flashes and feeling really terrible.
  • 59:35But there have been all these small
  • 59:38studies and when I was guilty of doing,
  • 59:40going along with some of these
  • 59:43small studies that said.
  • 59:44It enhanced your memory at made,
  • 59:46made a woman's skin better and
  • 59:49all kinds of stuff.
  • 59:50And it turned out it when somebody actually
  • 59:53did the giant randomized control trial.
  • 59:55It wasn't the case.
  • 59:57Well, maybe then part of the you know,
  • 60:00science. Education that science
  • 01:00:02journalists give should be more
  • 01:00:04focused on the process of science.
  • 01:00:06Rather, the process of
  • 01:00:07science before you knowing the
  • 01:00:09process of science before you report
  • 01:00:11it is very important and that there
  • 01:00:13are organizations like Annenberg
  • 01:00:15Foundation supports a lot of of
  • 01:00:17it's called there's a journalist.
  • 01:00:19Tip Sheet is not just about science,
  • 01:00:21but it tells you how to.
  • 01:00:24How to approach this subject and
  • 01:00:26to think about it and frame it.
  • 01:00:28And you might want to talk to.
  • 01:00:31Look at these resources and there is
  • 01:00:33the AAA S the American associated with
  • 01:00:35advancement of science has a whole
  • 01:00:37lot of resources for journalists,
  • 01:00:39so because a lot of mainstream publications
  • 01:00:41have cut back on their science reporting,
  • 01:00:44so you don't have people who do it day
  • 01:00:46in and day out who know the process.
  • 01:00:49So that's why you get the
  • 01:00:51somebody from USA TODAY.
  • 01:00:52Calling somebody out, asking stupid
  • 01:00:54questions because they they don't have.
  • 01:00:56They don't have background.
  • 01:00:57They used to have a lot.
  • 01:00:59USA TODAY as an example.
  • 01:01:01They used to have a big size step.
  • 01:01:04And if they laid off almost all an.
  • 01:01:09So there, but for people who want
  • 01:01:12good information is out there.
  • 01:01:14I think that there's not a danger that.
  • 01:01:17An when things happen that scare
  • 01:01:20public health people enough,
  • 01:01:23the.
  • 01:01:25Like vaccine hesitancy,
  • 01:01:26there is a growing movement to
  • 01:01:28handle it correctly.
  • 01:01:29It hasn't worked with edit
  • 01:01:31global warming yet,
  • 01:01:32but I think is young people get
  • 01:01:35more interested in adults.
  • 01:01:36It is more of a defining
  • 01:01:38issue than they have when I
  • 01:01:41certainly hope so, especially
  • 01:01:42for creating great grandchildren.
  • 01:01:44I don't think it's going
  • 01:01:45to be great. I think as
  • 01:01:48we grandchildren,
  • 01:01:49grandchildren they're going to
  • 01:01:51really have to look at these.
  • 01:01:53120 degree Fahrenheit days.
  • 01:01:55There are occurring out regularly in
  • 01:01:58Bombay and these water tables going
  • 01:02:00down all over the world and crop
  • 01:02:03shifting and things like Dengue a
  • 01:02:05moving North in a big hurry because
  • 01:02:08of mosquitoes are moving or it's
  • 01:02:10those are all that matters and well,
  • 01:02:13maybe we should be re channel
  • 01:02:15their energy into global warming.
  • 01:02:17May be very helpful thing.
  • 01:02:19Well thank you so much for coming.
  • 01:02:22Yeah, I've really enjoyed speaking with
  • 01:02:35Hope you enjoyed that episode.
  • 01:02:37Thanks again to Bob for being on the podcast.
  • 01:02:40You can find Bob on Twitter at Robert
  • 01:02:42Buzzell and that's at Robert Bazell.
  • 01:02:44You can also find him at his adjunct
  • 01:02:47faculty profile page at yale.edu.
  • 01:02:49You could also purchase this book her too,
  • 01:02:51at your favorite bookseller.
  • 01:02:53Pretty sure I picked up a copy on
  • 01:02:55Amazon.com and it arrived in two days.
  • 01:02:58It was awesome.
  • 01:02:59Thanks to the Yale School of
  • 01:03:01Medicine for sponsoring the podcast,
  • 01:03:03and especially to Adrian Bottom
  • 01:03:05Burger for producing this podcast
  • 01:03:07and Ryan McEvoy for sound editing.
  • 01:03:09Special thanks to you for listening again.
  • 01:03:11My name is Daniel Barron
  • 01:03:12and I've been your host.
  • 01:03:13An will see you next time on science at all.