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Ian Krop, MD, PhD

Professor of Internal Medicine (Medical Oncology)
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Additional Titles

Director, Clinical Trials Office

Chief Clinical Research Officer, Yale Cancer Center

Associate Director, Clinical Sciences, Yale Cancer Center

About

Titles

Professor of Internal Medicine (Medical Oncology)

Director, Clinical Trials Office; Chief Clinical Research Officer, Yale Cancer Center; Associate Director, Clinical Sciences, Yale Cancer Center

Biography

An international leader in the clinical care of patients with breast cancer, Dr. Krop joined Yale from Dana-Farber Cancer Institute where he was the Associate Chief of the Division of Breast Oncology and an Associate Professor of Medicine at Harvard Medical School. Nationally, he serves as Chief Scientific Officer for the Translational Breast Cancer Research Consortium and the Co-Vice Chair for Correlative Science for the Alliance for Clinical Trials in Oncology. His research efforts have advanced the field through clinical trials that define the next generation of therapies for patients. Dr. Krop serves as a member of the NCI Breast Cancer Steering Committee and the Data Monitoring Committee for ECOG/ACRIN. He also serves on the Data and Safety Monitoring Boards for multiple phase III trials.

Appointments

Other Departments & Organizations

Education & Training

PhD
Johns Hopkins University School of Medicine, Biochemistry, Cellular and Molecular Biology
MD
The Johns Hopkins University School of Medicine, Medicine

Research

Overview

Medical Subject Headings (MeSH)

Breast Diseases

Research at a Glance

Yale Co-Authors

Frequent collaborators of Ian Krop's published research.

Publications

2024

Clinical Care

Overview

Ian Krop, MD, PhD, is a professor of internal medicine, specializing in medical oncology, at Yale School of Medicine. He is a Yale Medicine specialist, with expertise in the management of breast cancer. Among his leadership roles at Yale Cancer Center, Dr. Krop serves as Associate Cancer Center Director for Clinical Research, Director of the Yale Cancer Center Clinical Trials Office, and Chief Clinical Research Officer.

Dr. Krop's research interests include the treatment of HER2-positive breast cancer through the investigation of various therapies, evaluation of genomic tools, and analysis of patient-reported outcomes. He participates in clinical trials that examine the role of neoadjuvant therapies in cancer treatment and ways to manage of spread of cancer to the brain. His work also examines patient-reported outcomes in breast cancer clinical trials and the correlation between the PIK3CA mutation and breast cancer outcomes.

Dr. Krop's research team has been awarded with grants from the National Cancer Institute, Susan G. Komen Breast Cancer Foundation, the Breast Cancer Research Foundation, and the American Association for Cancer Research. His work has significantly influenced patient care and medical education, leading to an improved understanding of resistance to HER2-directed therapies, the identification of potential tumor suppressors, and strategies to overcome residual disease in HER2-positive breast cancer.

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