Department of Pathology—The Lucille & Joseph Madri Lecture: "Single Cell Analysis of Circulating Tumor Cells"

The Lucille & Joseph Madri lecture was established through the generosity of Lucille and Joseph Madri to highlight groundbreaking basic and translational research in Yale’s Department of Pathology. This year's lecturer is Daniel A. Haber, MD, PhD.

Dr. Daniel Haber is Director of the Mass General Hospital Cancer Center for Research; and the Kurt Isselbacher Professor of Oncology at Harvard Medical School (HMS). He received his MD/Phd from Stanford in 1983, completed an internal medicine residency at Mass General, clinical oncology training at Dana-Farber Cancer Institute (DFCI), and a postdoctoral research fellowship at MIT. He joined the faculty of HMS in 1991.

Dr. Haber's numerous awards include a MERIT Award from the National Cancer Institute, a Dream Team Award from the Prostate Cancer Foundation and a Dream Team Award from Stand-Up-To-Cancer, and the Richard and Linda Rosenthal Memorial Award from the American Association for Cancer Research (AACR). He was appointed to the Howard Hughes Medical Institute in 2008, and he was elected to the Institute of Medicine in 2009, the American Academy of Arts and Sciences in 2011, and the National Academy of Sciences in 2018. He was elected a Fellow of the American Association for Cancer Research (AACR) in 2019.

Dr. Haber's research has focused primarily in the field of Cancer genetic, resulting in discoveries on the origin of the pediatric kidney cancer Wilms tumor, genetic predispositions to breast cancer, and mutations that define a subset of "non-smoker" lung cancers that are uniquely sensitive to targeted new therapies. In collaboration with Mass General bioengineer Dr. Mehmet Toner, Dr. Haber's Laboratory has developed a novel technology for isolating rare circulating tumor cells (CTCs) from the blood of cancer patients-a tool that may have profound implications for early diagnosis of cancer and non-invasive molecular profiling of cancers during therapy.