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Bioinformatics workshop series

Session 8: Functional analysis using Gene Set Enrichment Analysis (GSEA)

Register: https://schedule.yale.edu/event/11975028


Presenter: Rolando Garcia-Milian, Bioinformatics Support Hub, CWML

Summary: Gene Set Enrichment Analysis (GSEA) (UC San Diego/Broad Institute) determines whether a set of genes shows statistically significant differences between two biological conditions (e.g., phenotypes). From this session/workshop you will learn how to run GSEA on your own datasets using the GSEA desktop application. During the session we will use a tutorial dataset that will be made available to all the registrants

You will learn how to:

  • Prepare your data and files for running GSEA.
  • Use the Molecular Signature Database (MSigDB).
  • Run GSEA analysis and the Leading-edge analysis and results interpretation.
  • Send and visualize the results using the Enrichment Map app.

This session is suitable for both beginner and intermediate users of GSEA.

Prerequisites:

  • Download and install the GSEA desktop version on your laptop.
  • Download and install Cytoscape software
  • A tutorial dataset will be made available to all registrants.
  • You may also use your HPC account to access GSEA in Yale Open OnDemand.

Speaker

  • Rolando Garcia-Milan
    Bioinformatics Support Hub, CWML

Admission

Free

Tag

Training