Kutluk Oktay
Research & Publications
Biography
News
Research Summary
Oktay laboratory focuses on DNA repair and BRCA gene function as it relates to gamete aging and fertility preservation. Oktay laboratory has discovered the role of BRCA gene function and related DNA double strand break repair genes in oocyte aging. In addition to translational work on fertility preservation, Oktay laboratory is currently focusing on upstream mechanisms that result in decline in BRCA function and DNA DSB repair deficiency.
Extensive Research Description
Dr. Oktay entered the field of reproductive biology by studying under the mentorship of a prominent researcher in reproductive aging, James Nelson, PhD, during his REI fellowship training in San Antonio, Texas. Under his tutelage, he first studied the role of chronically elevated serum FSH levels in explaining the seemingly accelerated rate of follicle loss in aging females, using a rodent model. [Oktay K, Karlikaya G, Bayrakceken A. New strategies in studying ovarian aging. In: Biology of Menopause. Bellini F (Ed). Springer-Verlac, NY: 2000; 80-88.], His interest in ovarian aging led him to a post-doctoral fellowship in Dr. Roger Gosden’s laboratory in the UK. There he developed in vitro as well as xenograft models to be able to study human ovarian follicle aging and regulation of early stage folliculogenesis. He also developed a single-follicle PCR method to analyze gene expression from primordial and preantral follicles. Using that technique, he showed, for the first time that primordial follicles did not express the FSH receptor gene. During his presence in the UK, he was exposed to new fertility preservation technologies, which led him to perform the first ovarian transplantation with cryopreserved ovarian tissue, as well as developing a heterotopic ovarian transplant technique in women. Furthermore, he developed specific ovarian stimulation protocols for women with estrogen-sensitive cancers for the purpose of embryo or oocyte cryopreservation prior to chemotherapy [Azim A, Costantini-Ferrando M, Oktay K. Safety of Fertility Preservation by Ovarian Stimulation with Letrozole and Gonadotropins in Patients with Breast Cancer: A Prospective Controlled Study. J Clin Oncol 2008 Jun 1;(16)2630-5. PMID: 18509175]. In the meantime, he kept hs focus on ovarian biology and showed that extracellular matrix played a key role in early follicular development. He then received a KO8 award to study the role of integrins in early folliculogenesis under the mentorship of Dr. Giancotti at MSKCC. There he discovered that JNK signaling regulates early folliculogenesis, and may do so by regulating G2/M transition of the cell cycle through a mechanism upstream of Aurora-B. In the last decade, Dr. Oktay observed that women with BRCA-mutations show low response to ovarian stimulation. His research team then found that oocytes are capable of self repair of chemotherapy-induced DNA double strand breaks (DSBs) via the activation of ATM-mediated DNA DSB repair. As a result his laboratory gathered more focus on BRCA-mutation carriers. In a recent study published in Science Translational Medicine, Oktay found that the ability to repair DSBs is crucial in maintenance of ovarian reserve. In the same study, his team showed that BRCA-mutations lead to lower serum AMH levels in women, and lower primordial follicle reserve in mice. His team also showed that oocytes of BRCA-mutation carriers gather higher number of DNA breaks with age (Lin et al J Clin Endoc Metabol 2017). Moreover, Oktay Lab found that S1P prevents chemotherapy-induced human primordial follicle death. Currently, his laboratory focuses on the molecular mechanisms of oocyte death induced by chemotherapy, aging, as well as other stressors, and prevention of such death by pharmacological means.
Coauthors
Research Interests
Aging; Ovarian Follicle; Ovary; Genes, BRCA1; Genes, BRCA2; Reproductive Techniques, Assisted; Fertility Preservation; Recombinational DNA Repair; Ovarian Reserve
Selected Publications
- COMPARISON OF RANDOM START CONTROLLED OVARIAN STIMULATION WITH STANDARD START IN LETROZOLE GONADOTROPIN CYCLES FOR FERTILITY PRESERVATION IN WOMEN WITH BREAST CANCERTuran V, Lafuente S, Arkfeld C, Oktay K. COMPARISON OF RANDOM START CONTROLLED OVARIAN STIMULATION WITH STANDARD START IN LETROZOLE GONADOTROPIN CYCLES FOR FERTILITY PRESERVATION IN WOMEN WITH BREAST CANCER Fertility And Sterility 2022, 118: e239-e240. DOI: 10.1016/j.fertnstert.2022.08.675.
- OOCYTE CRYOPRESERVATION WITH IN VITRO MATURATION, A FEASIBLE OPTION FOR FERTILITY PRESERVATION IN ADOLESCENTS WITH MOSAIC TURNER SYNDROMELafuente S, Turan V, Oktay K. OOCYTE CRYOPRESERVATION WITH IN VITRO MATURATION, A FEASIBLE OPTION FOR FERTILITY PRESERVATION IN ADOLESCENTS WITH MOSAIC TURNER SYNDROME Fertility And Sterility 2022, 118: e69. DOI: 10.1016/j.fertnstert.2022.08.214.
- IS IT SAFE TO PERFORM OVARIAN CRYOPRESERVATION AND TRANSPLANTATION IN PATIENTS WITH LEUKEMIA A 5-YEAR SURVIVAL ANALYSIS DATASonmezer M, Sükür Y, Saçinti K, Ozkavukcu S, Kankaya D, Seval G, Atabekoglu C, Oktay K. IS IT SAFE TO PERFORM OVARIAN CRYOPRESERVATION AND TRANSPLANTATION IN PATIENTS WITH LEUKEMIA A 5-YEAR SURVIVAL ANALYSIS DATA Fertility And Sterility 2022, 118: e202. DOI: 10.1016/j.fertnstert.2022.08.575.
- PRESENCE OF BRCA MUTATIONS AND A PRE-CHEMOTHERAPY AMH LEVEL OF < 2ng/ML STRONGLY PREDICT RISK OF AMENORRHEA IN WOMEN WITH BREAST CANCEROktay K, Turan V, Bedoschi G, Goldfarb S, Bang H. PRESENCE OF BRCA MUTATIONS AND A PRE-CHEMOTHERAPY AMH LEVEL OF < 2ng/ML STRONGLY PREDICT RISK OF AMENORRHEA IN WOMEN WITH BREAST CANCER Fertility And Sterility 2022, 118: e231. DOI: 10.1016/j.fertnstert.2022.08.652.
- Anatomic nomenclature and 3-dimensional regional model of the human ovary: call for a new paradigmO'Neill KE, Maher JY, Laronda MM, Duncan FE, LeDuc RD, Lujan ME, Oktay KH, Pouch AM, Segars JH, Tsui EL, Zelinski MB, Halvorson LM, Gomez-Lobo V. Anatomic nomenclature and 3-dimensional regional model of the human ovary: call for a new paradigm American Journal Of Obstetrics And Gynecology 2022, 228: 270-275.e4. PMID: 36191605, PMCID: PMC9974561, DOI: 10.1016/j.ajog.2022.09.040.
- Laparoscopic ovarian tissue harvesting for cryopreservation from a child with galactosemiaVash-Margita A, Szymanska-Vandendriessche K, Gunther K, Rodriguez-Buritica DF, Christison-Lagay E, Saluja S, Oktay KH. Laparoscopic ovarian tissue harvesting for cryopreservation from a child with galactosemia Fertility And Sterility 2022, 118: 982-984. PMID: 36154768, DOI: 10.1016/j.fertnstert.2022.08.005.
- P-477 Ovarian stimulation and PGT-A outcomes with random start letrozole protocol for fertility preservation in breast cancer patientsArkfeld C, Gayete-Lafuente S, Turan V, Oktay K. P-477 Ovarian stimulation and PGT-A outcomes with random start letrozole protocol for fertility preservation in breast cancer patients Human Reproduction 2022, 37 DOI: 10.1093/humrep/deac107.449.
- Abstract P4-10-16: Increased chemotherapy-induced ovarian reserve loss and impaired oocyte quality in a mouse ATM knock-down model: An augury for women with ATM-pathway-pathogenic-variants-associated breast cancer?Oktay K, Tan X, Szymanska-Vandendriessche K. Abstract P4-10-16: Increased chemotherapy-induced ovarian reserve loss and impaired oocyte quality in a mouse ATM knock-down model: An augury for women with ATM-pathway-pathogenic-variants-associated breast cancer? Cancer Research 2022, 82: p4-10-16-p4-10-16. DOI: 10.1158/1538-7445.sabcs21-p4-10-16.
- Impact of chemotherapy on the ovarian reserve: Are all primordial follicles created equal?Oktay K, Marin L, Titus S. Impact of chemotherapy on the ovarian reserve: Are all primordial follicles created equal? Fertility And Sterility 2022, 117: 396-398. PMID: 34998576, DOI: 10.1016/j.fertnstert.2021.12.007.
- Fertility Preservation in Breast Cancer PatientsMarin L, Turan V, Oktay K. Fertility Preservation in Breast Cancer Patients 2022, 185-198. DOI: 10.1007/978-3-030-47767-7_14.
- Chapter 19 Ovarian Tissue Cryopreservation for Delaying Childbearing and MenopauseOktay K, Marin L. Chapter 19 Ovarian Tissue Cryopreservation for Delaying Childbearing and Menopause 2022, 193-201. DOI: 10.1016/b978-0-12-823344-3.00003-0.
- Appendix1 Instructional Videos for Ovarian Tissue Harvesting, Cryopreservation, and Patient CounselingMarin L, Oktay K. Appendix1 Instructional Videos for Ovarian Tissue Harvesting, Cryopreservation, and Patient Counseling 2022, 229-231. DOI: 10.1016/b978-0-12-823344-3.00005-4.
- Chapter 11 Preoperative Evaluation and Preparation for Ovarian Tissue Transplant SurgeryOktay K, Turan V. Chapter 11 Preoperative Evaluation and Preparation for Ovarian Tissue Transplant Surgery 2022, 109-115. DOI: 10.1016/b978-0-12-823344-3.00009-1.
- Chapter 18 Approach to Ovarian Stimulation and In Vitro Fertilization in Patients With Transplanted Ovarian TissueOktay K, Babayev S. Chapter 18 Approach to Ovarian Stimulation and In Vitro Fertilization in Patients With Transplanted Ovarian Tissue 2022, 185-192. DOI: 10.1016/b978-0-12-823344-3.00010-8.
- Appendix2 Materials, Equipment, and Protocols for Ovarian Tissue Cryopreservation and ThawingSzymanska-Vandendriessche K, Oktay K. Appendix2 Materials, Equipment, and Protocols for Ovarian Tissue Cryopreservation and Thawing 2022, 233-237. DOI: 10.1016/b978-0-12-823344-3.00012-1.
- Chapter 17 Approach to Follow Up After Ovarian TransplantationPacheco F, Oktay K. Chapter 17 Approach to Follow Up After Ovarian Transplantation 2022, 177-184. DOI: 10.1016/b978-0-12-823344-3.00015-7.
- Chapter 1 Scientific History of Ovarian Tissue Cryopreservation and TransplantationMarin L, Oktay K. Chapter 1 Scientific History of Ovarian Tissue Cryopreservation and Transplantation 2022, 1-9. DOI: 10.1016/b978-0-12-823344-3.00017-0.
- Appendix3 Materials, Equipment, and Operating Room Set-Up for Ovarian Tissue TransplantationBedoschi G, Taylan E, Oktay K. Appendix3 Materials, Equipment, and Operating Room Set-Up for Ovarian Tissue Transplantation 2022, 239-242. DOI: 10.1016/b978-0-12-823344-3.00018-2.
- Chapter 22 Future Aspects of Ovarian Cryopreservation and TransplantationMarin L, Taylan E, Oktay K. Chapter 22 Future Aspects of Ovarian Cryopreservation and Transplantation 2022, 221-227. DOI: 10.1016/b978-0-12-823344-3.00021-2.
- Chapter 15 Surgical Approach to Laparoscopic and Robot-Assisted Ovarian Tissue TransplantationOktay K, Bedoschi G. Chapter 15 Surgical Approach to Laparoscopic and Robot-Assisted Ovarian Tissue Transplantation 2022, 157-167. DOI: 10.1016/b978-0-12-823344-3.00023-6.
- Ovarian transplantation with robotic surgery and a neovascularizing human extracellular matrix scaffold: a case series in comparison to meta-analytic dataOktay K, Marin L, Bedoschi G, Pacheco F, Sugishita Y, Kawahara T, Taylan E, Acosta C, Bang H. Ovarian transplantation with robotic surgery and a neovascularizing human extracellular matrix scaffold: a case series in comparison to meta-analytic data Fertility And Sterility 2021, 117: 181-192. PMID: 34801235, PMCID: PMC8863399, DOI: 10.1016/j.fertnstert.2021.08.034.
- OVARIAN TISSUE HARVESTING AND CRYOPRESERVATION FROM A TODDLER WITH CLASSIC GALACTOSEMIA: A MULTIDISCIPLINARY APPROACHVash-Margita A, Szymanska K, Saluja S, Christison-Lagay E, Oktay K. OVARIAN TISSUE HARVESTING AND CRYOPRESERVATION FROM A TODDLER WITH CLASSIC GALACTOSEMIA: A MULTIDISCIPLINARY APPROACH Fertility And Sterility 2021, 116: e466-e467. DOI: 10.1016/j.fertnstert.2021.07.1171.
- AUTOLOGOUS CRYOPRESERVED OVARIAN TISSUE TRANSPLANTATION (ACOTT): AN UPDATE FROM OUR PREVIOUS META-ANALYTICAL DATASET AS OF MARCH 2021Pacheco F, Marin L, Oktay K. AUTOLOGOUS CRYOPRESERVED OVARIAN TISSUE TRANSPLANTATION (ACOTT): AN UPDATE FROM OUR PREVIOUS META-ANALYTICAL DATASET AS OF MARCH 2021 Fertility And Sterility 2021, 116: e217. DOI: 10.1016/j.fertnstert.2021.07.590.
- FERTILITY PRESERVATION MANAGEMENT AND OVARIAN TISSUE CRYOPRESERVATION IN AN INFANT GIRL WITH CLASSIC GALACTOSEMIASzymanska K, Vash-Margita A, Gunther K, Rodriguez-Buritica D, Oktay K. FERTILITY PRESERVATION MANAGEMENT AND OVARIAN TISSUE CRYOPRESERVATION IN AN INFANT GIRL WITH CLASSIC GALACTOSEMIA Fertility And Sterility 2021, 116: e57. DOI: 10.1016/j.fertnstert.2021.07.162.
- DOES HARVESTING OVARIAN TISSUE TO DELAY REPRODUCTIVE AGING HAVE A NEGATIVE IMPACT ON THE NATURAL AGE OF MENOPAUSE IN HEALTHY WOMEN?Petrikovsky B, Marin L, Oktay K. DOES HARVESTING OVARIAN TISSUE TO DELAY REPRODUCTIVE AGING HAVE A NEGATIVE IMPACT ON THE NATURAL AGE OF MENOPAUSE IN HEALTHY WOMEN? Fertility And Sterility 2021, 116: e9. DOI: 10.1016/j.fertnstert.2021.07.032.
- COMPARISON OF ORTHOTOPIC (OA) AND HETEROTOPIC (HA) AUTOLOGOUS CRYOPRESERVED OVARIAN TISSUE TRANSPLANTATION (ACOTT) OUTCOMESOktay K, Marin L. COMPARISON OF ORTHOTOPIC (OA) AND HETEROTOPIC (HA) AUTOLOGOUS CRYOPRESERVED OVARIAN TISSUE TRANSPLANTATION (ACOTT) OUTCOMES Fertility And Sterility 2021, 116: e68-e69. DOI: 10.1016/j.fertnstert.2021.07.194.
- Comparison of open and a novel closed vitrification system with slow freezing for human ovarian tissue cryopreservationSugishita Y, Taylan E, Kawahara T, Shahmurzada B, Suzuki N, Oktay K. Comparison of open and a novel closed vitrification system with slow freezing for human ovarian tissue cryopreservation Journal Of Assisted Reproduction And Genetics 2021, 38: 2723-2733. PMID: 34398400, PMCID: PMC8581089, DOI: 10.1007/s10815-021-02297-9.
- Female InfertilityOktay K, Taylan E. Female Infertility 2021, 1375-1381. DOI: 10.1093/med/9780198870197.003.0165.
- Association of Germline BRCA Pathogenic Variants With Diminished Ovarian Reserve: A Meta-Analysis of Individual Patient-Level DataTuran V, Lambertini M, Lee D, Wang E, Clatot F, Karlan B, Demeestere I, Bang H, Oktay K. Association of Germline BRCA Pathogenic Variants With Diminished Ovarian Reserve: A Meta-Analysis of Individual Patient-Level Data Journal Of Clinical Oncology 2021, 39: 2016-2024. PMID: 33891474, PMCID: PMC8260903, DOI: 10.1200/jco.20.02880.
- Delaying Reproductive Aging by Ovarian Tissue Cryopreservation and Transplantation: Is it Prime Time?Oktay K, Marin L, Petrikovsky B, Terrani M, Babayev S. Delaying Reproductive Aging by Ovarian Tissue Cryopreservation and Transplantation: Is it Prime Time? Trends In Molecular Medicine 2021, 27: 753-761. PMID: 33549473, PMCID: PMC8427891, DOI: 10.1016/j.molmed.2021.01.005.
- Individual-oocyte transcriptomic analysis shows that genotoxic chemotherapy depletes human primordial follicle reserve in vivo by triggering proapoptotic pathways without growth activationTitus S, Szymanska K, Musul B, Turan V, Taylan E, Garcia- Milian R, Mehta S, Oktay K. Individual-oocyte transcriptomic analysis shows that genotoxic chemotherapy depletes human primordial follicle reserve in vivo by triggering proapoptotic pathways without growth activation Scientific Reports 2021, 11: 407. PMID: 33431979, PMCID: PMC7801500, DOI: 10.1038/s41598-020-79643-x.
- Impact of adjuvant chemotherapy or tamoxifen-alone on the ovarian reserve of young women with breast cancerGoldfarb S, Turan V, Bedoschi G, Taylan E, Abdo N, Cigler T, Bang H, Patil S, Dickler M, Oktay K. Impact of adjuvant chemotherapy or tamoxifen-alone on the ovarian reserve of young women with breast cancer Breast Cancer Research And Treatment 2020, 185: 165-173. PMID: 32930927, PMCID: PMC7877450, DOI: 10.1007/s10549-020-05933-7.
- IMPACT OF ADJUVANT CHEMOTHERAPY OR TAMOXIFEN ALONE ON THE OVARIAN RESERVE OF YOUNG WOMEN WITH BREAST CANCER: A PROSPECTIVE LONGITUDINAL STUDYOktay K, Turan V, Bedoschi G, Taylan E, Bang H, Dickler M, Goldfarb S. IMPACT OF ADJUVANT CHEMOTHERAPY OR TAMOXIFEN ALONE ON THE OVARIAN RESERVE OF YOUNG WOMEN WITH BREAST CANCER: A PROSPECTIVE LONGITUDINAL STUDY Fertility And Sterility 2020, 114: e531-e532. DOI: 10.1016/j.fertnstert.2020.09.051.
- Unraveling the mechanisms of chemotherapy-induced damage to human primordial follicle reserve: road to developing therapeutics for fertility preservation and reversing ovarian aging.Szymanska K, Tan X, Oktay K. Unraveling the mechanisms of chemotherapy-induced damage to human primordial follicle reserve: road to developing therapeutics for fertility preservation and reversing ovarian aging. Molecular Human Reproduction 2020, 26: 553-566. PMID: 32514568, PMCID: PMC7411370, DOI: 10.1093/molehr/gaaa043.
- Expert Commentary on Fertility Preservation in Colorectal Cancers: Current State and Practical Tips for the Cancer Practitioner.Oktay K. Expert Commentary on Fertility Preservation in Colorectal Cancers: Current State and Practical Tips for the Cancer Practitioner. Diseases Of The Colon & Rectum 2020, 63: 726-727. PMID: 32384403, DOI: 10.1097/dcr.0000000000001688.
- Impact of breast cancer chemotherapy on ovarian damage and recovery.Goldfarb S, Bedoschi G, Turan V, Crown A, Abdo N, Dickler M, Oktay K. Impact of breast cancer chemotherapy on ovarian damage and recovery. Journal Of Clinical Oncology 2020, 38: e24059-e24059. DOI: 10.1200/jco.2020.38.15_suppl.e24059.
- BRCA-related ATM-mediated DNA double-strand break repair and ovarian agingTuran V, Oktay K. BRCA-related ATM-mediated DNA double-strand break repair and ovarian aging Human Reproduction Update 2019, 26: 43-57. PMID: 31822904, PMCID: PMC6935693, DOI: 10.1093/humupd/dmz043.
- Ovarian Stimulation in Women with Breast CancerTuran V, Oktay K. Ovarian Stimulation in Women with Breast Cancer 2019, 105-115. DOI: 10.1007/978-3-030-24086-8_10.
- Fertility preservation in gynecologic cancersTaylan E, Oktay K. Fertility preservation in gynecologic cancers Gynecologic Oncology 2019, 155: 522-529. PMID: 31604663, DOI: 10.1016/j.ygyno.2019.09.012.
- Advances in fertility-preservation surgery: navigating new frontiersChristianson M, Oktay K. Advances in fertility-preservation surgery: navigating new frontiers Fertility And Sterility 2019, 112: 438-445. PMID: 31446903, DOI: 10.1016/j.fertnstert.2019.06.029.
- Chemotherapy causes primordial follicle death in the human ovary via multiple apoptotic pathways and not by “burn out”Titus S, Oktay K. Chemotherapy causes primordial follicle death in the human ovary via multiple apoptotic pathways and not by “burn out” Fertility And Sterility 2019, 112: e84. DOI: 10.1016/j.fertnstert.2019.07.340.
- Fertility preservation in girls with Turner syndrome: limitations, current success and future prospectsOktay K, Bedoschi G. Fertility preservation in girls with Turner syndrome: limitations, current success and future prospects Fertility And Sterility 2019, 111: 1124-1126. PMID: 31056311, DOI: 10.1016/j.fertnstert.2019.03.018.
- Abstract PD6-06: Impact of BRCA mutations on chemotherapy-induced loss of ovarian reserve: A prospective longitudinal studyOktay K, Bedoschi G, Goldfarb S, Taylan E, Titus S, Palomaki G, Cigler T, Robson M, Dickler M. Abstract PD6-06: Impact of BRCA mutations on chemotherapy-induced loss of ovarian reserve: A prospective longitudinal study Cancer Research 2019, 79: pd6-06-pd6-06. DOI: 10.1158/1538-7445.sabcs18-pd6-06.
- Chapter 30 Autologous Transplantation of Human Ovarian TissueTaylan E, Oktay K. Chapter 30 Autologous Transplantation of Human Ovarian Tissue 2019, 493-500. DOI: 10.1016/b978-0-12-813209-8.00030-3.
- Robot-assisted orthotopic and heterotopic ovarian tissue transplantation techniquesOktay K, Kawahara T, Taylan E, Cillo G. Robot-assisted orthotopic and heterotopic ovarian tissue transplantation techniques Fertility And Sterility 2018, 110: e425. DOI: 10.1016/j.fertnstert.2018.07.1125.
- Ovarian tissue vitrification using open and closed devices, and thawing procedureSugishita Y, Kawahara T, Taylan E, Oktay K, Suzuki N. Ovarian tissue vitrification using open and closed devices, and thawing procedure Fertility And Sterility 2018, 110: e426. DOI: 10.1016/j.fertnstert.2018.07.1132.
- Comparison of embryo aneuploidy rates and patterns between brca mutation carriers and infertile womenOktay K, Turan V, Palomaki G, Munne S, Sawarkar S, Escudero T. Comparison of embryo aneuploidy rates and patterns between brca mutation carriers and infertile women Fertility And Sterility 2018, 110: e148-e149. DOI: 10.1016/j.fertnstert.2018.07.439.
- Feasibility and success of fertility preservation in childrenTaylan E, Sugishita Y, Kawahara T, Ursillo L, Oktay K. Feasibility and success of fertility preservation in children Fertility And Sterility 2018, 110: e185. DOI: 10.1016/j.fertnstert.2018.07.543.
- Increased chemotherapy-induced ovarian reserve loss in women with BRCA mutations: a prospective longitudinal study with mechanistic confirmationOktay K, Bedoschi G, Goldfarb S, Titus S, Palomaki G, Dickler M. Increased chemotherapy-induced ovarian reserve loss in women with BRCA mutations: a prospective longitudinal study with mechanistic confirmation Fertility And Sterility 2018, 110: e430. DOI: 10.1016/j.fertnstert.2018.08.035.
- Ovarian tissue cryopreservation and transplantationBedoschi G, Oktay K. Ovarian tissue cryopreservation and transplantation 2018, 148-152. DOI: 10.1201/9781351141680-19.
- Abstract PD7-07: Failure of goserelin to prevent chemotherapy-induced damage to ovarian reserveOktay K, Taylan E, Sugishita Y, Kawahara T, Suzuki N. Abstract PD7-07: Failure of goserelin to prevent chemotherapy-induced damage to ovarian reserve Cancer Research 2018, 78: pd7-07-pd7-07. DOI: 10.1158/1538-7445.sabcs17-pd7-07.
- Ovarian Stimulation and the Long-Term Risk of CancerTaylan E, Oktay K. Ovarian Stimulation and the Long-Term Risk of Cancer 2018, 344-348. DOI: 10.1016/b978-0-12-801238-3.64898-5.
- GnRHA co-treatment does not prevent chemotherapy-induced primordial follicle loss and DNA damageTaylan E, Sugishita Y, Kawahara T, Oktay K. GnRHA co-treatment does not prevent chemotherapy-induced primordial follicle loss and DNA damage Fertility And Sterility 2017, 108: e186. DOI: 10.1016/j.fertnstert.2017.07.552.
- Comparison of open and closed devices in human ovarian tissue vitrificationSugishita Y, Taylan E, Kawahara T, Suzuki N, Oktay K. Comparison of open and closed devices in human ovarian tissue vitrification Fertility And Sterility 2017, 108: e172-e173. DOI: 10.1016/j.fertnstert.2017.07.514.
- Association of germline BRCA mutations with impaired fertility preservation cycle outcomesTuran V, Moy F, Oktay K. Association of germline BRCA mutations with impaired fertility preservation cycle outcomes Fertility And Sterility 2017, 108: e187-e188. DOI: 10.1016/j.fertnstert.2017.07.555.
- Vitrification versus slow freezing of human ovarian tissue: a comparison of follicle survival and DNA damageKawahara T, Sugishita Y, Taylan E, Suzuki N, Moy F, Oktay K. Vitrification versus slow freezing of human ovarian tissue: a comparison of follicle survival and DNA damage Fertility And Sterility 2017, 108: e56-e57. DOI: 10.1016/j.fertnstert.2017.07.179.
- Fertility Preservation in Cancer PatientsOktay K. Fertility Preservation in Cancer Patients Oncology Times 2017, 39: 1,8-9. DOI: 10.1097/01.cot.0000513308.74211.af.
- Recent advances in vitrification of human ovarian tissue and tandem IVM oocytesSugishita Y, Oktay K. Recent advances in vitrification of human ovarian tissue and tandem IVM oocytes Cryobiology 2016, 73: 416. DOI: 10.1016/j.cryobiol.2016.09.070.
- Current succes and efficiency of autologous ovarian transplantation with cryopreserved tissue: a meta-analysisOktay K, Pacheco F. Current succes and efficiency of autologous ovarian transplantation with cryopreserved tissue: a meta-analysis Fertility And Sterility 2016, 106: e131-e132. DOI: 10.1016/j.fertnstert.2016.07.392.
- Tissue recovery and in vitro maturation of immature oocytes as a fertility preservation strategy for tandem ovarian, oocyte, and embryo cryopreservationSugishita Y, Suzuki N, Moy F, Oktay K. Tissue recovery and in vitro maturation of immature oocytes as a fertility preservation strategy for tandem ovarian, oocyte, and embryo cryopreservation Fertility And Sterility 2016, 106: e54. DOI: 10.1016/j.fertnstert.2016.07.166.
- Embryo Cryopreservation in Breast Cancer PatientsBedoschi G, Oktay K. Embryo Cryopreservation in Breast Cancer Patients 2016, 39-52. DOI: 10.1007/978-4-431-55963-4_3.
- Current State of Fertility Preservation in Cancer Patients—What is Established and What is Still Controversial?Oktay K, Bedoschi G. Current State of Fertility Preservation in Cancer Patients—What is Established and What is Still Controversial? Oncology & Hematology Review (US) 2016, 12: 33. DOI: 10.17925/ohr.2016.12.01.33.
- Comparison of random start controlled ovarian stimulation with standard start in letrozole gonadotropin cycles for fertility preservation in women with breast cancerBedoschi G, Turan V, Emirdar V, Sonmezer M, Oktay K. Comparison of random start controlled ovarian stimulation with standard start in letrozole gonadotropin cycles for fertility preservation in women with breast cancer Fertility And Sterility 2015, 104: e267. DOI: 10.1016/j.fertnstert.2015.07.838.
- Safety of controlled ovarian stimulation with gonadotropins and letrozole in women with BRCA mutationsKim J, Turan V, Oktay K. Safety of controlled ovarian stimulation with gonadotropins and letrozole in women with BRCA mutations Fertility And Sterility 2015, 104: e265. DOI: 10.1016/j.fertnstert.2015.07.832.
- Value of Antimullerian hormone and antral follicle count in predicting fertility preservation cycle outcomesEmirdar V, Turan V, Moy F, Bedoschi G, Oktay K. Value of Antimullerian hormone and antral follicle count in predicting fertility preservation cycle outcomes Fertility And Sterility 2015, 104: e264. DOI: 10.1016/j.fertnstert.2015.07.829.
- BRCA1/2 gene mutations are associated with diminished primordial follicle density and increased oocyte DNA damage in the human ovaryLin W, Titus S, Ginsburg E, Oktay K. BRCA1/2 gene mutations are associated with diminished primordial follicle density and increased oocyte DNA damage in the human ovary Fertility And Sterility 2015, 104: e7-e8. DOI: 10.1016/j.fertnstert.2015.07.023.
- Sperm quality and fertility are compromised in brca1 mutant male miceStobezki R, Titus S, Musul B, Moy F, Oktay K. Sperm quality and fertility are compromised in brca1 mutant male mice Fertility And Sterility 2015, 104: e81. DOI: 10.1016/j.fertnstert.2015.07.248.
- Does follicle flushing during oocyte retrieval improve fertility preservation cycle outcomes?Emirdar V, Turan V, Pacheco F, Oktay K. Does follicle flushing during oocyte retrieval improve fertility preservation cycle outcomes? Fertility And Sterility 2015, 104: e184-e185. DOI: 10.1016/j.fertnstert.2015.07.572.
- The optimal number of oocytes to thaw in a frozen donor oocyte cycle: an individual patient data meta-analysis from 540 thaw cyclesKim J, Cil A, Oktay K. The optimal number of oocytes to thaw in a frozen donor oocyte cycle: an individual patient data meta-analysis from 540 thaw cycles Fertility And Sterility 2015, 104: e197. DOI: 10.1016/j.fertnstert.2015.07.612.
- Menstruation is an unreliable surrogate in the assessment of ovarian damage by chemotherapy: a prospective longitudinal study with AMH levels as the gold standardBedoschi G, Goldfarb S, Quistorff J, Goswami S, Moy F, Dickler M, Oktay K. Menstruation is an unreliable surrogate in the assessment of ovarian damage by chemotherapy: a prospective longitudinal study with AMH levels as the gold standard Fertility And Sterility 2015, 104: e262-e263. DOI: 10.1016/j.fertnstert.2015.07.825.
- Long-term safety of fertility preservation by ovarian stimulation and concurrent aromatase inhibitor treatment in women with breast cancer.Oktay K, Turan V, Kim J. Long-term safety of fertility preservation by ovarian stimulation and concurrent aromatase inhibitor treatment in women with breast cancer. Journal Of Clinical Oncology 2015, 33: 9521-9521. DOI: 10.1200/jco.2015.33.15_suppl.9521.
- The impact of adjuvant breast cancer (BC) chemotherapy on ovarian reserve and menses.Goldfarb S, Bedoschi G, Grunblatt E, Goswami S, Cigler T, Quistorff J, Pacheco F, Stobezki R, Robson M, Moy F, Hudis C, Patil S, Dickler M, Oktay K. The impact of adjuvant breast cancer (BC) chemotherapy on ovarian reserve and menses. Journal Of Clinical Oncology 2015, 33: 9522-9522. DOI: 10.1200/jco.2015.33.15_suppl.9522.
- Abstract P1-09-06: A prospective longitudinal study of the impact of breast cancer treatment with adjuvant chemotherapy or tamoxifen alone on ovarian reserveGoldfarb S, Bedoschi G, Grunblatt E, Goswami S, Cigler T, Quistorff J, Pacheco F, Stobezki R, Robson M, Moy F, Hudis C, Patil S, Dickler M, Oktay K. Abstract P1-09-06: A prospective longitudinal study of the impact of breast cancer treatment with adjuvant chemotherapy or tamoxifen alone on ovarian reserve 2015, p1-09-06-p1-09-06. DOI: 10.1158/1538-7445.sabcs14-p1-09-06.
- Abstract P5-15-02: Safety of letrozole-gonadotropin controlled ovarian stimulation protocol in women with breast cancer undergoing fertility preservation before or after tumor resection via embryo or oocyte cryopreservation: A prospective cohort studyOktay K, Kim J, Bedoschi G, Turan V. Abstract P5-15-02: Safety of letrozole-gonadotropin controlled ovarian stimulation protocol in women with breast cancer undergoing fertility preservation before or after tumor resection via embryo or oocyte cryopreservation: A prospective cohort study 2015, p5-15-02-p5-15-02. DOI: 10.1158/1538-7445.sabcs14-p5-15-02.
- Chapter 4 The Current Understanding of Clinical Data on Ovarian Toxicity from Cancer TreatmentTuran V, Oktay K. Chapter 4 The Current Understanding of Clinical Data on Ovarian Toxicity from Cancer Treatment 2015, 47-61. DOI: 10.1016/b978-0-12-801591-9.00004-7.
- Ovarian Tissue Cryopreservation: Where Are We Now?Bedoschi G, Oktay K. Ovarian Tissue Cryopreservation: Where Are We Now? 2015, 71-78. DOI: 10.1007/978-3-319-17849-3_6.
- A prospective longitudinal study of the impact of breast cancer chemotherapy on ovarian reserve: do individuals have differing susceptibilities?Oktay K, Goldfarb S, Bedoschi G, Quistorff J, Grunblatt E, Cigler T, Moy F, Patil S, Goswami S, Dickler M. A prospective longitudinal study of the impact of breast cancer chemotherapy on ovarian reserve: do individuals have differing susceptibilities? Fertility And Sterility 2014, 102: e151. DOI: 10.1016/j.fertnstert.2014.07.517.
- Declining DNA double strand break repair results in male reproductive agingStobezki R, Titus S, Halicka D, Darzynkiewicz Z, Oktay K. Declining DNA double strand break repair results in male reproductive aging Fertility And Sterility 2014, 102: e110. DOI: 10.1016/j.fertnstert.2014.07.378.
- Efficacy of serum follicle-stimulating hormone level monitoring during letrozole-gonadotropin ovarian stimulation cyclesKim J, Turan V, Bedoschi G, Oktay K. Efficacy of serum follicle-stimulating hormone level monitoring during letrozole-gonadotropin ovarian stimulation cycles Fertility And Sterility 2014, 102: e163. DOI: 10.1016/j.fertnstert.2014.07.557.
- The use of a “double trigger” for fertility preservation in poor respondersPacheco F, Small A, Acosta C, Acosta K, Dunn S, Oktay K. The use of a “double trigger” for fertility preservation in poor responders Fertility And Sterility 2014, 102: e163. DOI: 10.1016/j.fertnstert.2014.07.558.
- Safety of fertility preservation by ovarian stimulation with letrozole and gonadotropin in patients with breast cancer: a prospective controlled study with subgroup analysisKim J, Turan V, Oktay K. Safety of fertility preservation by ovarian stimulation with letrozole and gonadotropin in patients with breast cancer: a prospective controlled study with subgroup analysis Fertility And Sterility 2014, 102: e32. DOI: 10.1016/j.fertnstert.2014.07.118.
- Robotically assisted ovarian tissue transplantation with human extracellular matrix: ovarian stimulation and in vitro fertilization outcomesOktay K, Bedoschi G, Pacheco F, Stobezki R, Turan V. Robotically assisted ovarian tissue transplantation with human extracellular matrix: ovarian stimulation and in vitro fertilization outcomes Fertility And Sterility 2014, 102: e37. DOI: 10.1016/j.fertnstert.2014.07.132.
- Sphingosine-1-phosphate, a protector against chemotherapy-induced ovarian follicle apoptosis, does not diminish the effectiveness of chemotherapyTitus S, Stobezki R, Turan V, Halicka D, De Sutter P, Oktay K. Sphingosine-1-phosphate, a protector against chemotherapy-induced ovarian follicle apoptosis, does not diminish the effectiveness of chemotherapy Fertility And Sterility 2014, 102: e39. DOI: 10.1016/j.fertnstert.2014.07.139.
- Fertility preservation and GnRHa for chemotherapy: debateBlumenfeld Z, Rodriguez-Wallberg K, Oktay K. Fertility preservation and GnRHa for chemotherapy: debate Cancer Management And Research 2014, Volume 6: 313-315. PMID: 25170279, PMCID: PMC4144983, DOI: 10.2147/cmar.s66600.
- Feasibility of ovarian stimulation and oocyte cryopreservation for fertility preservation in female childrenBedoschi G, Turan V, Oktay K. Feasibility of ovarian stimulation and oocyte cryopreservation for fertility preservation in female children Fertility And Sterility 2013, 100: s63-s64. DOI: 10.1016/j.fertnstert.2013.07.1877.
- The impact of long-term tamoxifen treatment on ovarian reserve markers in women with breast cancer: a prospective-longitudinal studyOktay K, Bedoschi G, Dickler M, Goldfarb S, Turan V, Moy F. The impact of long-term tamoxifen treatment on ovarian reserve markers in women with breast cancer: a prospective-longitudinal study Fertility And Sterility 2013, 100: s64. DOI: 10.1016/j.fertnstert.2013.07.1879.
- Simplified cycle management for breast cancer patients undergoing fertility preservation with the Letrozole-FSH stimulation protocolBedoschi G, Turan V, Moy F, Oktay K. Simplified cycle management for breast cancer patients undergoing fertility preservation with the Letrozole-FSH stimulation protocol Fertility And Sterility 2013, 100: s169. DOI: 10.1016/j.fertnstert.2013.07.1468.
- Male mice show significant age-induced decline in sperm DNA integrityStobezki R, Titus S, Darzynkiewicz Z, Oktay K. Male mice show significant age-induced decline in sperm DNA integrity Fertility And Sterility 2013, 100: s5. DOI: 10.1016/j.fertnstert.2013.07.138.
- Frozen embryo transfer pregnancy outcomes in breast cancer patients who were stimulated with Letrozole-FSH for fertility preservationBedoschi G, Turan V, Oktay K. Frozen embryo transfer pregnancy outcomes in breast cancer patients who were stimulated with Letrozole-FSH for fertility preservation Fertility And Sterility 2013, 100: s166. DOI: 10.1016/j.fertnstert.2013.07.1455.
- Safety and feasibility of performing two consecutive Letrozole-FSH stimulation cycles for fertility preservation in women with breast cancerBedoschi G, Turan V, Oktay K. Safety and feasibility of performing two consecutive Letrozole-FSH stimulation cycles for fertility preservation in women with breast cancer Fertility And Sterility 2013, 100: s65. DOI: 10.1016/j.fertnstert.2013.07.1883.
- Fertility preservation options in women with endometriosis.Bedoschi G, Turan V, Oktay K. Fertility preservation options in women with endometriosis. Minerva Obstetrics And Gynecology 2013, 65: 99-103. PMID: 23598777.
- Fertility preservation in young breast cancer patients: addressing individual patient needsRodriguez-Wallberg K, Oktay K. Fertility preservation in young breast cancer patients: addressing individual patient needs Breast Cancer Management 2013, 2: 135-147. DOI: 10.2217/bmt.12.68.
- Fertility preservation in the female with cancerRodriguez-Wallberg K, Oktay K. Fertility preservation in the female with cancer 2013, 273-281. DOI: 10.1017/cbo9780511997761.031.
- Approach to Fertility Preservation in Adult and Prepubertal FemalesRodriguez-Wallberg K, Oktay K. Approach to Fertility Preservation in Adult and Prepubertal Females 2012, 307-318. DOI: 10.1007/978-1-4614-5617-9_18.
- Comparison of leuprolide vs hCG trigger in letrozole-gonadotropin fertility preservation cyclesOktay K, Ozkaya E, Reddy J, Moy F. Comparison of leuprolide vs hCG trigger in letrozole-gonadotropin fertility preservation cycles Fertility And Sterility 2012, 98: s118. DOI: 10.1016/j.fertnstert.2012.07.437.
- Impact of number of oocytes thawed and the day of embryo transfer on ivf success rates with vitrified donor oocytes: an individual patient data meta-analysis from 508 thaw cyclesCil A, Rosen M, Oktay K. Impact of number of oocytes thawed and the day of embryo transfer on ivf success rates with vitrified donor oocytes: an individual patient data meta-analysis from 508 thaw cycles Fertility And Sterility 2012, 98: s75. DOI: 10.1016/j.fertnstert.2012.07.271.
- Letrozole plus gonadotropin is superior to gonadotropin alone in fertility preservation cyclesOzkaya E, Moy F, Oktay K. Letrozole plus gonadotropin is superior to gonadotropin alone in fertility preservation cycles Fertility And Sterility 2012, 98: s9-s10. DOI: 10.1016/j.fertnstert.2012.07.034.
- Serum FSH levels on trigger-day can predict oocyte maturity rate in in vitro fertilization cyclesOzkaya E, Reddy J, Moy F, Oktay K. Serum FSH levels on trigger-day can predict oocyte maturity rate in in vitro fertilization cycles Fertility And Sterility 2012, 98: s119-s120. DOI: 10.1016/j.fertnstert.2012.07.442.
- Sphingosine-1-phosphate prevents human primordial follicle death induced by a diverse set of chemotherapy agentsLi F, Akula K, Ozkaya E, De Sutter P, Oktay K. Sphingosine-1-phosphate prevents human primordial follicle death induced by a diverse set of chemotherapy agents Fertility And Sterility 2012, 98: s69. DOI: 10.1016/j.fertnstert.2012.07.247.
- Germline BRCA1 gene mutations result in accelerated ovarian aging: a translational studyOktay K, Li F, Stubezski R, Jeong K, Dickler M, Titus S. Germline BRCA1 gene mutations result in accelerated ovarian aging: a translational study Fertility And Sterility 2012, 98: s24. DOI: 10.1016/j.fertnstert.2012.07.089.
- Utility of serum FSH monitoring in letrozole-gonadotropin cycles in women with breast cancerOzkaya E, Moy F, Reddy J, Oktay K. Utility of serum FSH monitoring in letrozole-gonadotropin cycles in women with breast cancer Fertility And Sterility 2012, 98: s122. DOI: 10.1016/j.fertnstert.2012.07.450.
- Evaluation of ovarian and testicular tissue cryopreservation and their bundling with medically-indicated procedures in children undergoing gonadotoxic therapies for blood dyscrasias or cancerBabayev S, Karsy M, Arslan E, Kogan S, Oktay K. Evaluation of ovarian and testicular tissue cryopreservation and their bundling with medically-indicated procedures in children undergoing gonadotoxic therapies for blood dyscrasias or cancer Fertility And Sterility 2012, 98: s36. DOI: 10.1016/j.fertnstert.2012.07.132.
- Impact of chemotherapy exposure on fertility preservation cycle outcomesJeong K, Karsy M, Oktay K. Impact of chemotherapy exposure on fertility preservation cycle outcomes Fertility And Sterility 2012, 98: s95. DOI: 10.1016/j.fertnstert.2012.07.348.
- Prevention of chemotherapy-induced damage to ovarian reserve by sphingosine-1-phosphateLI F, Ozkaya E, Akula K, Desutter P, Oktay K. Prevention of chemotherapy-induced damage to ovarian reserve by sphingosine-1-phosphate Journal Of Clinical Oncology 2012, 30: 1097-1097. DOI: 10.1200/jco.2012.30.15_suppl.1097.
- Retraction notice to “Impaired DNA repair as the root cause of oocyte aging” Fertil Steril 96(2011)S239Oktay K, Heytens E, Soleimani R, Baltaci V, Goswami S. Retraction notice to “Impaired DNA repair as the root cause of oocyte aging” Fertil Steril 96(2011)S239 Fertility And Sterility 2012, 97: 1018. PMID: 22570855, DOI: 10.1016/j.fertnstert.2012.02.033.
- The Patient with a History of Estrogen‐Receptor Positive CancerSönmezer M, Oktay K. The Patient with a History of Estrogen‐Receptor Positive Cancer 2012, 205-207. DOI: 10.1002/9781444398854.ch49.
- Ovarian cryopreservation.Jeong K, Aslan E, Ozkaya E, Sonmezer M, Oktay K. Ovarian cryopreservation. Minerva Medica 2012, 103: 37-46. PMID: 22278067.
- SESSION 52: REPRODUCTIVE ENDOCRINOLOGY 2Oktay K, Ozkaya E, Moy F, Schuring A, Busch A, Bogdanova N, Gromoll J, Tuttelmann F, Kovanci E, Schutt A, Gibbons W, Mazur E, Narkwichean A, Maalouf W, Hernandez Medrano J, Jayaprakasan K, Campbell B. SESSION 52: REPRODUCTIVE ENDOCRINOLOGY 2 Human Reproduction 2012, 27: ii74-ii76. DOI: 10.1093/humrep/27.s2.51.
- OC14.06: The role of antral follicle counts (AFC) via TVUSG in determining fertility preservation outcomes in cancer patients undergoing ovarian stimulationArslan E, Karsy M, Moy F, Oktay K. OC14.06: The role of antral follicle counts (AFC) via TVUSG in determining fertility preservation outcomes in cancer patients undergoing ovarian stimulation Ultrasound In Obstetrics And Gynecology 2011, 38: 27-27. DOI: 10.1002/uog.9171.
- The effect of taxanes on menstruation and ovarian reserve in women with breast cancerArslan E, Karsy M, Moy F, Oktay K. The effect of taxanes on menstruation and ovarian reserve in women with breast cancer Fertility And Sterility 2011, 96: s77. DOI: 10.1016/j.fertnstert.2011.07.298.
- RETRACTED: Impaired DNA repair as the root cause of oocyte agingOktay K, Heytens E, Soleimani R, Baltaci V, Goswami S. RETRACTED: Impaired DNA repair as the root cause of oocyte aging Fertility And Sterility 2011, 96: s239. DOI: 10.1016/j.fertnstert.2011.07.916.
- Fertility preservation provides hope to cancer patientsRosen A, Oktay K. Fertility preservation provides hope to cancer patients Fertility And Sterility 2011, 96: s9-s10. DOI: 10.1016/j.fertnstert.2011.07.044.
- Sphingosine-1-phosphate accelerates neoangiogenesis, reduces hypoxia, and improves primordial follicle survival in human ovarian xenografts: a prelude to improving ovarian transplantation outcomesSoleimani R, Heytens E, Oktay K. Sphingosine-1-phosphate accelerates neoangiogenesis, reduces hypoxia, and improves primordial follicle survival in human ovarian xenografts: a prelude to improving ovarian transplantation outcomes Fertility And Sterility 2011, 96: s34. DOI: 10.1016/j.fertnstert.2011.07.138.
- Comparison of IVF-ET cycles using vitrified donor versus nondonor oocytes: a pooled analysis of 705 thaw cyclesCil A, Oktay K. Comparison of IVF-ET cycles using vitrified donor versus nondonor oocytes: a pooled analysis of 705 thaw cycles Fertility And Sterility 2011, 96: s86-s87. DOI: 10.1016/j.fertnstert.2011.07.333.
- The role of combined anti-mullerian hormone and antral follicle count assessment in predicting cycle outcomes in cancer patients undergoing controlled ovarian stimulation for fertility preservationArslan E, Karsy M, Moy F, Oktay K. The role of combined anti-mullerian hormone and antral follicle count assessment in predicting cycle outcomes in cancer patients undergoing controlled ovarian stimulation for fertility preservation Fertility And Sterility 2011, 96: s201. DOI: 10.1016/j.fertnstert.2011.07.778.
- The impact of chemotherapy on IVF outcomesKarsy M, Arslan E, Moy F, Oktay K. The impact of chemotherapy on IVF outcomes Fertility And Sterility 2011, 96: s202. DOI: 10.1016/j.fertnstert.2011.07.784.
- In vivo impact of doxorubicin on ovarian germ cell and non-germ cell population: double strand DNA breaks and microvascular damageSoleimani R, Heytens E, Oktay K. In vivo impact of doxorubicin on ovarian germ cell and non-germ cell population: double strand DNA breaks and microvascular damage Fertility And Sterility 2011, 96: s96-s97. DOI: 10.1016/j.fertnstert.2011.07.381.
- The safety of ovarian and testicular cryopreservation in childrenKarsy M, Arslan E, Kogan S, Oktay K. The safety of ovarian and testicular cryopreservation in children Fertility And Sterility 2011, 96: s216. DOI: 10.1016/j.fertnstert.2011.07.832.
- Age-based success rates after elective oocyte cryopreservation (EOC): a pooled analysis of 2281 thaw cyclesCil A, Oktay K. Age-based success rates after elective oocyte cryopreservation (EOC): a pooled analysis of 2281 thaw cycles Fertility And Sterility 2011, 96: s211. DOI: 10.1016/j.fertnstert.2011.07.815.
- Long-term experience with ovarian tissue cryopreservation and transplantationGore S, Heytens E, Karsy M, Cuadri M, Soleimani R, Oktay K. Long-term experience with ovarian tissue cryopreservation and transplantation Fertility And Sterility 2011, 96: s31. DOI: 10.1016/j.fertnstert.2011.07.125.
- Safety of pregnancy after letrozole-FSH stimulation in breast cancer patients: a prospective comparison of frozen embryo transfer to self vs. gestational carriersOktay K, Arslan E, Karsy M, Moy F. Safety of pregnancy after letrozole-FSH stimulation in breast cancer patients: a prospective comparison of frozen embryo transfer to self vs. gestational carriers Fertility And Sterility 2011, 96: s42-s43. DOI: 10.1016/j.fertnstert.2011.07.162.
- Approach to Fertility Preservation in Adult and Prepubertal FemalesRodriguez-Wallberg K, Oktay K. Approach to Fertility Preservation in Adult and Prepubertal Females 2011, 233-241. DOI: 10.1007/978-1-4419-1783-6_18.
- Reply of the AuthorsOktay K, Türkçüoğlu I, Rodriguez-Wallberg K. Reply of the Authors Fertility And Sterility 2011, 95: e51. DOI: 10.1016/j.fertnstert.2011.03.089.
- A multicenter analysis of the predictors of fertility preservation in women with breast cancer: Role of neoadjuvant chemotherapy.Kim J, Oktay K, Gracia C, Lee S, Morse C, Mersereau J. A multicenter analysis of the predictors of fertility preservation in women with breast cancer: Role of neoadjuvant chemotherapy. Journal Of Clinical Oncology 2011, 29: 9118-9118. DOI: 10.1200/jco.2011.29.15_suppl.9118.
- Infertility as a risk factor of ovarian and breast cancerKim J, Oktay K. Infertility as a risk factor of ovarian and breast cancer Expert Review Of Obstetrics & Gynecology 2011, 6: 153-161. DOI: 10.1586/eog.11.2.
- Access to fertility preservation and post-chemotherapy assisted reproduction in women with breast cancerLee S, Heytens E, Ozkavukcu S, Rosen A, Moy F, Oktay K. Access to fertility preservation and post-chemotherapy assisted reproduction in women with breast cancer Fertility And Sterility 2010, 94: s66. DOI: 10.1016/j.fertnstert.2010.07.258.
- Age of natural menopause in BRCA1/2 mutation carriersLin W, Beattie M, Chen L, Cedars M, Oktay K, Rosen M. Age of natural menopause in BRCA1/2 mutation carriers Fertility And Sterility 2010, 94: s43. DOI: 10.1016/j.fertnstert.2010.07.168.
- The prevalence of self-reported reproductive impairment in young female cancer survivors throughout CaliforniaLetourneau J, Katz P, Smith J, Oktay K, Cedars M, Rosen M. The prevalence of self-reported reproductive impairment in young female cancer survivors throughout California Fertility And Sterility 2010, 94: s10. DOI: 10.1016/j.fertnstert.2010.07.039.
- Spingosine-1-phosphate enhances neo-angiogenesis in human ovarian transplants in scid miceSoleimani R, Heytens E, Oktay K. Spingosine-1-phosphate enhances neo-angiogenesis in human ovarian transplants in scid mice Fertility And Sterility 2010, 94: s107. DOI: 10.1016/j.fertnstert.2010.07.441.
- Serum FSH monitoring in letrozole-FSH in vitro fertilization cyclesOktay K, Lee S, Moy F, Heytens E, Fourcade H. Serum FSH monitoring in letrozole-FSH in vitro fertilization cycles Fertility And Sterility 2010, 94: s256. DOI: 10.1016/j.fertnstert.2010.07.992.
- Prevention of chemotherapy-induced apoptotic follicular death in human ovary by ceramide-induced death pathway inhibitorsSoleimani R, Heytens E, Oktay K. Prevention of chemotherapy-induced apoptotic follicular death in human ovary by ceramide-induced death pathway inhibitors Fertility And Sterility 2010, 94: s11. DOI: 10.1016/j.fertnstert.2010.07.042.
- Improving autologous ovarian transplantation with frozen-banked tissue: robotic assistance and the utilization of a human regenerative matrixOktay K, Soleimani R, Lee S, Ozkavukcu S, Brito M, Babayev S. Improving autologous ovarian transplantation with frozen-banked tissue: robotic assistance and the utilization of a human regenerative matrix Fertility And Sterility 2010, 94: s89. DOI: 10.1016/j.fertnstert.2010.07.344.
- Does higher starting dose of FSH stimulation improve fertility preservation cycle outcomes in women with breast cancer?Oktay K, Lee S. Does higher starting dose of FSH stimulation improve fertility preservation cycle outcomes in women with breast cancer? Fertility And Sterility 2010, 94: s160. DOI: 10.1016/j.fertnstert.2010.07.637.
- Long-term outcomes and safety of letrozole-FSH protocol in women with breast cancer undergoing fertility preservation: a prospective-controlled studyOktay K, Lee S, Kim J, Moy F. Long-term outcomes and safety of letrozole-FSH protocol in women with breast cancer undergoing fertility preservation: a prospective-controlled study Fertility And Sterility 2010, 94: s11. DOI: 10.1016/j.fertnstert.2010.07.041.
- Ovarian reserve assesment in patients with multiple sclerosisCil A, Leventoglu A, Sonmezer M, Uzdogan A, Guler Z, Oktay K. Ovarian reserve assesment in patients with multiple sclerosis Fertility And Sterility 2010, 94: s98. DOI: 10.1016/j.fertnstert.2010.07.410.
- Assesment of ovarian reserve in patients with behcet's diseaseCil A, Sonmezer M, Kocak M, Karabulut A, Akbiyik F, Oktay K. Assesment of ovarian reserve in patients with behcet's disease Fertility And Sterility 2010, 94: s96-s97. DOI: 10.1016/j.fertnstert.2010.07.405.
- Value of early referral to improve fertility preservation outcomes in women with breast cancer.Oktay K, Lee S, Ozkavukcu S, Heytens E, Alappat R. Value of early referral to improve fertility preservation outcomes in women with breast cancer. Journal Of Clinical Oncology 2010, 28: 9026-9026. DOI: 10.1200/jco.2010.28.15_suppl.9026.
- Preserving FertilityOktay K, Oktem O. Preserving Fertility 2010, 703-710. DOI: 10.1007/978-1-4419-1436-1_47.
- In vitro maturation improves oocyte or embryo cryopreservation outcome in breast cancer patients undergoing ovarian stimulation for fertility preservationOktay K, Buyuk E, Rodriguez-Wallberg K, Sahin G. In vitro maturation improves oocyte or embryo cryopreservation outcome in breast cancer patients undergoing ovarian stimulation for fertility preservation Reproductive BioMedicine Online 2010, 20: 634-638. PMID: 20219430, DOI: 10.1016/j.rbmo.2010.01.012.
- Fertility Preservation for Breast Cancer PatientsOktem1 O, Oktay1 K. Fertility Preservation for Breast Cancer Patients Seminars In Reproductive Medicine 2009, 27: 486-492. PMID: 19806518, DOI: 10.1055/s-0029-1241059.
- Association of BRCA1 gene mutations with diminished ovarian reserve: a novel connection between DNA repair and ovarian aging in humansOktay K, Kim J, Barad D, Babayev S. Association of BRCA1 gene mutations with diminished ovarian reserve: a novel connection between DNA repair and ovarian aging in humans Fertility And Sterility 2009, 92: s30-s31. DOI: 10.1016/j.fertnstert.2009.07.119.
- Recurrent spontaneous pregnancies and live births following heterotopic transplantation of frozen banked ovarian tissue despite the absence of follicular activity in the remaining menopausal ovaryOktay K. Recurrent spontaneous pregnancies and live births following heterotopic transplantation of frozen banked ovarian tissue despite the absence of follicular activity in the remaining menopausal ovary Fertility And Sterility 2009, 92: s66. DOI: 10.1016/j.fertnstert.2009.07.255.
- Stem cells and reproductive medicine.Oktem O, Oktay K. Stem cells and reproductive medicine. Minerva Obstetrics And Gynecology 2009, 61: 247-52. PMID: 19745792.
- Fertility preservation medicine: A new field in the care of young cancer survivors—responseOktay K, Sonmezer M, Oktem O. Fertility preservation medicine: A new field in the care of young cancer survivors—response Pediatric Blood & Cancer 2009, 53: 1160-1160. DOI: 10.1002/pbc.22154.
- Reply of the authors: Evidence-based medicine or just a theory?Oktay K, Sönmezer M, Wallberg K. Reply of the authors: Evidence-based medicine or just a theory? Fertility And Sterility 2009, 92: e10. DOI: 10.1016/j.fertnstert.2009.03.071.
- Association of BRCA1 mutations with diminished ovarian reserve: A common genetic mechanism for breast/ovarian cancer, and infertility?Oktay K, Kim J, Barad D, Gleicher N, Babayev S. Association of BRCA1 mutations with diminished ovarian reserve: A common genetic mechanism for breast/ovarian cancer, and infertility? Journal Of Clinical Oncology 2009, 27: 11039-11039. DOI: 10.1200/jco.2009.27.15_suppl.11039.
- Recent Advances in Fertility Preservation for the FemaleOktem O, Oktay K. Recent Advances in Fertility Preservation for the Female 2009, 95-102. DOI: 10.1007/978-1-60327-392-3_6.
- Gonadotropin-releasing hormone agonists for prevention of chemotherapy-induced ovarian damage: prospective randomized study Badawy A, Elnashar A, El-Ashry M, et al (Mansura Univ, Egypt; et al) Fertil Steril 91:694-697, 2009§Oktay K, Sönmezer M. Gonadotropin-releasing hormone agonists for prevention of chemotherapy-induced ovarian damage: prospective randomized study Badawy A, Elnashar A, El-Ashry M, et al (Mansura Univ, Egypt; et al) Fertil Steril 91:694-697, 2009§ Breast Diseases A Year Book Quarterly 2009, 20: 458-460. DOI: 10.1016/s1043-321x(09)79420-2.
- Incomplete pregnancy is not associated with breast cancer risk: the California Teachers Study Henderson KD, Sullivan-Halley J, Reynolds P, et al (City of Hope Comprehensive Cancer Ctr, Duarte, CA; Northern California Cancer Center, Fremont, CA; et al) Contraception 77:391-396, 2008§Türkçüoğlu I, Oktay K. Incomplete pregnancy is not associated with breast cancer risk: the California Teachers Study Henderson KD, Sullivan-Halley J, Reynolds P, et al (City of Hope Comprehensive Cancer Ctr, Duarte, CA; Northern California Cancer Center, Fremont, CA; et al) Contraception 77:391-396, 2008§ Breast Diseases A Year Book Quarterly 2009, 19: 316-318. DOI: 10.1016/s1043-321x(08)79171-9.
- Ovarian tissue cryopreservation and other fertility preservation strategiesBuyuk E, Oktem O, Sonmezer M, Oktay K. Ovarian tissue cryopreservation and other fertility preservation strategies 2008, 327-341. DOI: 10.3109/9780203092934-26.
- A meta-analytic comparison of oocyte vitrification to slow freezing: time trends and the current state of the technologyCil A, Oktem O, Oktay K. A meta-analytic comparison of oocyte vitrification to slow freezing: time trends and the current state of the technology Fertility And Sterility 2008, 90: s269-s270. DOI: 10.1016/j.fertnstert.2008.07.1154.
- Serum FSH monitoring improves decision making in women undergoing controlled ovarian hyperstimulation with letrozole and follicle stimulating hormoneOktay K, Kim J, Barad D, Gleicher N, Blanchette H. Serum FSH monitoring improves decision making in women undergoing controlled ovarian hyperstimulation with letrozole and follicle stimulating hormone Fertility And Sterility 2008, 90: s183-s184. DOI: 10.1016/j.fertnstert.2008.07.779.
- Relevance of low expansion CGG triple repeats numbers on the FMR1 gene to functional ovarian reserveGleicher N, Weghofer A, Oktay K, Barad D. Relevance of low expansion CGG triple repeats numbers on the FMR1 gene to functional ovarian reserve Fertility And Sterility 2008, 90: s58. DOI: 10.1016/j.fertnstert.2008.07.766.
- Breast cancer diagnosis following controlled ovarian stimulation: are the tumors different?Sonmezer M, Oktem O, Cil A, Oktay K. Breast cancer diagnosis following controlled ovarian stimulation: are the tumors different? Fertility And Sterility 2008, 90: s268. DOI: 10.1016/j.fertnstert.2008.07.1205.
- c-Jun N-terminal kinase (JNK) pathway controls granulosa cell mitosis: a novel mechanism in regulation of preantral follicle growthOktem O, Oktay K. c-Jun N-terminal kinase (JNK) pathway controls granulosa cell mitosis: a novel mechanism in regulation of preantral follicle growth Fertility And Sterility 2008, 90: s330. DOI: 10.1016/j.fertnstert.2008.07.1663.
- Comparison of predictive value of anti-mullerian hormone (AMH) and day 3 follicle stimulating hormone for pregnancy and oocyte retrievalBarad D, Oktay K, Weghofer A, Gleicher N. Comparison of predictive value of anti-mullerian hormone (AMH) and day 3 follicle stimulating hormone for pregnancy and oocyte retrieval Fertility And Sterility 2008, 90: s473. DOI: 10.1016/j.fertnstert.2008.07.171.
- Longevity of autologous ovarian transplants: extended experience in humansOktay K, Oktem O, Barad D, Gleicher N. Longevity of autologous ovarian transplants: extended experience in humans Fertility And Sterility 2008, 90: s53. DOI: 10.1016/j.fertnstert.2008.07.724.
- Fertility preservation is an emerging discipline extending beyond cancer patients: analysis of a large experienceOktay K, Sahin G, Ucar K, Barad D, Blanchette H, Gleicher N. Fertility preservation is an emerging discipline extending beyond cancer patients: analysis of a large experience Fertility And Sterility 2008, 90: s51. DOI: 10.1016/j.fertnstert.2008.07.719.
- Triple CGG expansions on the FMR1 gene and response to ovarian stimulationBarad D, Weghofer A, Oktay K, Gleicher N. Triple CGG expansions on the FMR1 gene and response to ovarian stimulation Fertility And Sterility 2008, 90: s233. DOI: 10.1016/j.fertnstert.2008.07.566.
- The distribution of causative etiologies in infertile women with a diagnosis of spontaneous premature ovarian senescence, exclusive of end-stage premature ovarian failure (POF)Gleicher N, Weghofer A, Oktay K, Barad D. The distribution of causative etiologies in infertile women with a diagnosis of spontaneous premature ovarian senescence, exclusive of end-stage premature ovarian failure (POF) Fertility And Sterility 2008, 90: s259. DOI: 10.1016/j.fertnstert.2008.07.1227.
- Dehydroepiandrosterone (DHEA) reduces miscarriage rates in women with diminished ovarian reserve: a multicenter studyGleicher N, Ryan E, Weghofer A, Oktay K, Blanco-Mejia S, Barad D. Dehydroepiandrosterone (DHEA) reduces miscarriage rates in women with diminished ovarian reserve: a multicenter study Fertility And Sterility 2008, 90: s258-s259. DOI: 10.1016/j.fertnstert.2008.07.1225.
- Anti-mullerian hormone (AMH), but not follicle stimulating hormone (FSH), correlates to oocyte yield in in vitro fertilizationBarad D, Oktay K, Weghofer A, Gleicher N. Anti-mullerian hormone (AMH), but not follicle stimulating hormone (FSH), correlates to oocyte yield in in vitro fertilization Fertility And Sterility 2008, 90: s259-s260. DOI: 10.1016/j.fertnstert.2008.07.1228.
- Autoimmune function and number of triple CGG expansions on the FMR1 gene as independent risk factors for premature ovarian senescenceGleicher N, Weghofer A, Oktay K, Barad D. Autoimmune function and number of triple CGG expansions on the FMR1 gene as independent risk factors for premature ovarian senescence Fertility And Sterility 2008, 90: s151. DOI: 10.1016/j.fertnstert.2008.07.274.
- The impact of immunomodulating drugs on ovarian reserve in multiple sclerosis patientsCil A, Leventoglu A, Yildiz G, Soylukoc R, Oktay K. The impact of immunomodulating drugs on ovarian reserve in multiple sclerosis patients Fertility And Sterility 2008, 90: s259. DOI: 10.1016/j.fertnstert.2008.07.1226.
- In Reply: Can GnRH Analogues Preserve Gonadal Function Without Preserving Fertility?Sönmezer M, Bang H, Oktay K. In Reply: Can GnRH Analogues Preserve Gonadal Function Without Preserving Fertility? The Oncologist 2008, 13: 615-617. DOI: 10.1634/theoncologist.2008-0053.
- Fertility Issues and Options in Young Women with CancerOktay K, Sönmezer M. Fertility Issues and Options in Young Women with Cancer 2008, 178: 203-224. PMID: 18080455, DOI: 10.1007/978-3-540-71274-9_18.
- Prospective follow up of children born following controlled ovarian hyperstimulation with combined continuous letrozole-gonadotropin protocolElassar A, Shahin G, Oktay K. Prospective follow up of children born following controlled ovarian hyperstimulation with combined continuous letrozole-gonadotropin protocol Fertility And Sterility 2007, 88: s338-s339. DOI: 10.1016/j.fertnstert.2007.07.1130.
- Fertility preservation with ovarian cryopreservation: a decade of experienceElassar A, Oktem O, Oktay K. Fertility preservation with ovarian cryopreservation: a decade of experience Fertility And Sterility 2007, 88: s12-s13. DOI: 10.1016/j.fertnstert.2007.07.061.
- Safety of ovarian stimulation with letrozole and gonadotropins in breast cancer patients undergoing embryo or oocyte cryopreservation: a prospective controlled studyAzim A, Oktay K. Safety of ovarian stimulation with letrozole and gonadotropins in breast cancer patients undergoing embryo or oocyte cryopreservation: a prospective controlled study Fertility And Sterility 2007, 88: s33. DOI: 10.1016/j.fertnstert.2007.07.121.
- Monitoring serum FSH levels to optimize IVF outcomes in patients treated with letrozole and gonadotropins what is the therapeutic serum FSH range?Shastri S, Azim A, Oktay K. Monitoring serum FSH levels to optimize IVF outcomes in patients treated with letrozole and gonadotropins what is the therapeutic serum FSH range? Fertility And Sterility 2007, 88: s95. DOI: 10.1016/j.fertnstert.2007.07.312.
- Sphingosine-1-phosphate enhances human primordial follicle survival and blocks ovarian apoptosis in vitroOktem O, Oktay K. Sphingosine-1-phosphate enhances human primordial follicle survival and blocks ovarian apoptosis in vitro Fertility And Sterility 2007, 88: s270. DOI: 10.1016/j.fertnstert.2007.07.918.
- Impact of previous chemotherapy on ovarian production of estradiol, progesterone, and AMH: an in vitro controlled studyOktem O, Oktay K. Impact of previous chemotherapy on ovarian production of estradiol, progesterone, and AMH: an in vitro controlled study Fertility And Sterility 2007, 88: s14. DOI: 10.1016/j.fertnstert.2007.07.066.
- A novel xenograft model to test the ovarian toxicity of chemotherapy agents in womenOktay K, Oktem O. A novel xenograft model to test the ovarian toxicity of chemotherapy agents in women Journal Of Clinical Oncology 2007, 25: 19504-19504. DOI: 10.1200/jco.2007.25.18_suppl.19504.
- In ReplyLee S, Oktay K. In Reply Journal Of Clinical Oncology 2006, 24: 5337-5338. DOI: 10.1200/jco.2006.08.6041.
- O-287 Ovarian reserve is impaired in cancer patients with normal baseline FSH who previously received chemotherapy as determined by response to controlled ovarian stimulation and anti-mullerian hormone measurements: A controlled studyAzim A, Rauch E, Ravich M, Witkin S, Oktay K. O-287 Ovarian reserve is impaired in cancer patients with normal baseline FSH who previously received chemotherapy as determined by response to controlled ovarian stimulation and anti-mullerian hormone measurements: A controlled study Fertility And Sterility 2006, 86: s123-s124. DOI: 10.1016/j.fertnstert.2006.07.327.
- O-292 A meta-analytic comparison of oocyte vitrification succes rates with slow freezing and the SART IVF data with unfrozen oocytesCil A, Bang H, Oktay K. O-292 A meta-analytic comparison of oocyte vitrification succes rates with slow freezing and the SART IVF data with unfrozen oocytes Fertility And Sterility 2006, 86: s126. DOI: 10.1016/j.fertnstert.2006.07.333.
- O-283 Comparative potency of anastrozole to suppress estradiol levels in breast cancer patients undergoing controlled ovarian stimulation prior to IVF: A pilot dose-finding studyAzim A, Costantini-Ferrando M, Lostritto K, Oktay K. O-283 Comparative potency of anastrozole to suppress estradiol levels in breast cancer patients undergoing controlled ovarian stimulation prior to IVF: A pilot dose-finding study Fertility And Sterility 2006, 86: s121-s122. DOI: 10.1016/j.fertnstert.2006.07.322.
- O-53 Normal female phenotype and ovarian development despite the gonadal expression of sex determining region of Y chromosome (SRY) in a 46, XX/69, XXY diploid/triploid mosaic child conceived after IVF-ICSIOktem O, Turkekul M, Xu K, Rosenwaks Z, Oktay K. O-53 Normal female phenotype and ovarian development despite the gonadal expression of sex determining region of Y chromosome (SRY) in a 46, XX/69, XXY diploid/triploid mosaic child conceived after IVF-ICSI Fertility And Sterility 2006, 86: s23. DOI: 10.1016/j.fertnstert.2006.07.064.
- O-223 A novel ovarian xenografting model to characterize the impact of chemotherapy agents on human primordial follicle reserveOktay K, Oktem O. O-223 A novel ovarian xenografting model to characterize the impact of chemotherapy agents on human primordial follicle reserve Fertility And Sterility 2006, 86: s95-s96. DOI: 10.1016/j.fertnstert.2006.07.255.
- P-165 The first live birth after the use of aromatase inhibitors for induction of ovulation in young women with endometrial carcinomaAzim A, Lostritto K, Oktay K. P-165 The first live birth after the use of aromatase inhibitors for induction of ovulation in young women with endometrial carcinoma Fertility And Sterility 2006, 86: s193-s194. DOI: 10.1016/j.fertnstert.2006.07.513.
- P-478 Fertility preservation in young women diagnosed with cervical carcinomaAzim A, Schattman G, Oktay K. P-478 Fertility preservation in young women diagnosed with cervical carcinoma Fertility And Sterility 2006, 86: s313. DOI: 10.1016/j.fertnstert.2006.07.841.
- O-227 Impact of breast cancer chemotherapy on ovarian reserve: A prospective analysis by menstrual history and ovarian reserve markersReh A, Oktem O, Lostritto K, Oktay K. O-227 Impact of breast cancer chemotherapy on ovarian reserve: A prospective analysis by menstrual history and ovarian reserve markers Fertility And Sterility 2006, 86: s97-s98. DOI: 10.1016/j.fertnstert.2006.07.259.
- In ReplyOktay K, Lee S. In Reply Journal Of Clinical Oncology 2006, 24: 4221-4222. DOI: 10.1200/jco.2006.07.4633.
- O-229 In vitro maturation increases the number of oocytes and embryos cryopreserved from cancer patients undergoing controlled ovarian hyperstimulation (COH) prior to chemotherapyOktay K, Azim A, Sahin G, Yin H, Zaninovic N, Veeck-Gosden L. O-229 In vitro maturation increases the number of oocytes and embryos cryopreserved from cancer patients undergoing controlled ovarian hyperstimulation (COH) prior to chemotherapy Fertility And Sterility 2006, 86: s98-s99. DOI: 10.1016/j.fertnstert.2006.07.261.
- P-408 Evidence for altered ovarian stromal function in women previously exposed to chemotherapyOktem O, Liu H, Oktay K. P-408 Evidence for altered ovarian stromal function in women previously exposed to chemotherapy Fertility And Sterility 2006, 86: s287. DOI: 10.1016/j.fertnstert.2006.07.768.
- O-166 FSH levels predict success in hyperresponders: How much “coasting” can a follicle withstand?Kang H, Reichman D, Liu H, Spandorfer S, Rosenwaks Z, Oktay K. O-166 FSH levels predict success in hyperresponders: How much “coasting” can a follicle withstand? Fertility And Sterility 2006, 86: s71. DOI: 10.1016/j.fertnstert.2006.07.192.
- P-477 Histological quantification of the impact of chemotherapy on human primordial follicle reserve in womenOktem O, Oktay K. P-477 Histological quantification of the impact of chemotherapy on human primordial follicle reserve in women Fertility And Sterility 2006, 86: s312-s313. DOI: 10.1016/j.fertnstert.2006.07.840.
- P-725 Correlation of antimullerian hormone levels with primordial follicle count in human ovaryOktem O, Sezen D, Oktay K. P-725 Correlation of antimullerian hormone levels with primordial follicle count in human ovary Fertility And Sterility 2006, 86: s402. DOI: 10.1016/j.fertnstert.2006.07.1110.
- Continuous Combined Letrozole-FSH Stimulation Requires Less FSH With Similar Outcomes Compared To Standard Ovarian Stimulation Regimens for IVFOktay K, Cil A, Oktem O, Bang H. Continuous Combined Letrozole-FSH Stimulation Requires Less FSH With Similar Outcomes Compared To Standard Ovarian Stimulation Regimens for IVF Fertility And Sterility 2005, 84: s94. DOI: 10.1016/j.fertnstert.2005.07.227.
- Integrin Beta-4 Signalling Plays a Key Role in Mouse EmbryogenesisRoberts J, Nikolopoulos S, Oktem O, Rosenwaks Z, Giancotti F, Oktay K. Integrin Beta-4 Signalling Plays a Key Role in Mouse Embryogenesis Fertility And Sterility 2005, 84: s7-s8. DOI: 10.1016/j.fertnstert.2005.07.017.
- Strong Family History in Women Who Were Diagnosed With Breast Cancer After In Vitro FertilizationSonmezer M, Akar M, Oktay K. Strong Family History in Women Who Were Diagnosed With Breast Cancer After In Vitro Fertilization Fertility And Sterility 2005, 84: s233-s234. DOI: 10.1016/j.fertnstert.2005.07.603.
- Comparative Efficiency of IVF Between Frozen-thawed and Fresh Oocytes: A Meta-AnalysisOktay K, Cil A, Veeck L, Bang H. Comparative Efficiency of IVF Between Frozen-thawed and Fresh Oocytes: A Meta-Analysis Fertility And Sterility 2005, 84: s37. DOI: 10.1016/j.fertnstert.2005.07.089.
- Relationship Between Structure in the Frozen State and Viability of Thawed Ovarian Tissue After CryopreservationGosden R, Morris G, Yin H, Bodine R, Oktay K. Relationship Between Structure in the Frozen State and Viability of Thawed Ovarian Tissue After Cryopreservation Fertility And Sterility 2005, 84: s34-s35. DOI: 10.1016/j.fertnstert.2005.07.083.
- Role of Extracellular Matrix, Activin-A and Mitogen Activated Protein Kinase (MAPK) Signaling Pathways in Preantral Follicle Growth and Survival in the MouseOktem O, Oktay K. Role of Extracellular Matrix, Activin-A and Mitogen Activated Protein Kinase (MAPK) Signaling Pathways in Preantral Follicle Growth and Survival in the Mouse Fertility And Sterility 2005, 84: s384-s385. DOI: 10.1016/j.fertnstert.2005.07.1007.
- Serum FSH Measurements During Coasting in IVF-Over Responders May Predict Pregnancy OutcomeAkar M, Liu H, Oktay K. Serum FSH Measurements During Coasting in IVF-Over Responders May Predict Pregnancy Outcome Fertility And Sterility 2005, 84: s258-s259. DOI: 10.1016/j.fertnstert.2005.07.671.
- Sustained Endocrine Function And Spontaneous Pregnancies After Subcutaneous Transplantation Of Cryopreserved Ovarian Tissue In Stem Cell Transplant RecipientsOktay K, Oktem O. Sustained Endocrine Function And Spontaneous Pregnancies After Subcutaneous Transplantation Of Cryopreserved Ovarian Tissue In Stem Cell Transplant Recipients Fertility And Sterility 2005, 84: s68. DOI: 10.1016/j.fertnstert.2005.07.162.
- Oocyte and Ovarian Tissue Cryopreservation: Indications, Techniques, and ApplicationsShamonki1 3, Oktay2 3. Oocyte and Ovarian Tissue Cryopreservation: Indications, Techniques, and Applications Seminars In Reproductive Medicine 2005, 23: 266-276. PMID: 16059833, DOI: 10.1055/s-2005-872455.
- Letrozole and tamoxifen as safer ovarian stimulants in women undergoing embryo cryopreservation for fertility preservation before breast cancer chemotherapy: A prospective controlled trialOktay K, Libertella N, Buyuk E, Lostritto K, Vickers A, Akar M. Letrozole and tamoxifen as safer ovarian stimulants in women undergoing embryo cryopreservation for fertility preservation before breast cancer chemotherapy: A prospective controlled trial Journal Of Clinical Oncology 2005, 23: 539-539. DOI: 10.1200/jco.2005.23.16_suppl.539.
- Fertility preservation in breast cancer patients: A prospective controlled comparison of ovarian stimulation with tamoxifen and letrozole for embryo cryopreservationOktay K, Buyuk E, Akar M, Rosenwaks Z, Libertella N. Fertility preservation in breast cancer patients: A prospective controlled comparison of ovarian stimulation with tamoxifen and letrozole for embryo cryopreservation Fertility And Sterility 2004, 82: s1. DOI: 10.1016/j.fertnstert.2004.07.007.
- Embryo Development After Heterotopic Transplantation of Cryopreserved Ovarian TissueOktay K, Buyuk E, Veeck L, Zaninovic N, Xu K, Takeuchi T, Opsahl M, Rosenwaks Z. Embryo Development After Heterotopic Transplantation of Cryopreserved Ovarian Tissue Obstetrical & Gynecological Survey 2004, 59: 520-522. DOI: 10.1097/00006254-200407000-00018.
- Novel use of an aromatase inhibitor for fertility preservation via embryo cryopreservation in endometrial cancer: a case reportOktay K, Buyuk E, Rosenwaks Z. Novel use of an aromatase inhibitor for fertility preservation via embryo cryopreservation in endometrial cancer: a case report Fertility And Sterility 2003, 80: 144. DOI: 10.1016/s0015-0282(03)01261-5.
- A prospective comparison of tamoxifen alone and tamoxifen-FSH combined protocol for IVF and fertility preservation in breast cancer patientsOktay K, Buyuk E, Davis O, Veeck L, Rosenwaks Z. A prospective comparison of tamoxifen alone and tamoxifen-FSH combined protocol for IVF and fertility preservation in breast cancer patients Fertility And Sterility 2003, 80: 63-64. DOI: 10.1016/s0015-0282(03)01973-3.
- Deciphering early folliculogenesis: Jun Amino Terminal Kinase (JNK) plays a key role in preantral follicle growthOktay K, Buyuk E, Oktem O, Oktay M, Rosenwaks Z, Giancotti F. Deciphering early folliculogenesis: Jun Amino Terminal Kinase (JNK) plays a key role in preantral follicle growth Fertility And Sterility 2003, 80: 26-27. DOI: 10.1016/s0015-0282(03)01871-5.
- In vitro growth of mouse primary and early preantral follicles in a 3-dimensional culture systemBuyuk E, Oktem O, Roberts J, Rosenwaks Z, Oktay K. In vitro growth of mouse primary and early preantral follicles in a 3-dimensional culture system Fertility And Sterility 2003, 80: 79. DOI: 10.1016/s0015-0282(03)02010-7.
- Activin responsive PAI-1 promoter activity in granulosa cells is dependent on attachment to extracellular matrixOktay K, Akman O, Buyuk E, Rosenwaks Z, Giancotti F. Activin responsive PAI-1 promoter activity in granulosa cells is dependent on attachment to extracellular matrix Fertility And Sterility 2002, 78: s221-s222. DOI: 10.1016/s0015-0282(02)04051-7.
- Fertility preservation in breast cancer patients: In vitro fertilization and embryo cryopreservation after ovarian stimulation with tamoxifenOktay K, Buyuk E, Davis O, Rosenwaks Z. Fertility preservation in breast cancer patients: In vitro fertilization and embryo cryopreservation after ovarian stimulation with tamoxifen Fertility And Sterility 2002, 78: s80. DOI: 10.1016/s0015-0282(02)03591-4.
- Extracellular matrix-activin interactions in granulosa cell growth and apoptosisBuyuk E, Oktay M, Giancotti F, Rosenwaks Z, Oktay K. Extracellular matrix-activin interactions in granulosa cell growth and apoptosis Fertility And Sterility 2002, 78: s106. DOI: 10.1016/s0015-0282(02)03660-9.
- The potential of ovarian tissue transplant to preserve fertilityBuyuk E, Oktay K. The potential of ovarian tissue transplant to preserve fertility Expert Opinion On Biological Therapy 2002, 2: 361-370. PMID: 11955275, DOI: 10.1517/14712598.2.4.361.
- Preliminary Experience with Orthotopic and Heterotopic Transplantation of Ovarian Cortical StripsOktay K, Yih M. Preliminary Experience with Orthotopic and Heterotopic Transplantation of Ovarian Cortical Strips Seminars In Reproductive Medicine 2002, 20: 063-074. PMID: 11941536, DOI: 10.1055/s-2002-23520.
- Ovarian tissue cryopreservation and transplantation: preliminary findings and implications for cancer patientsOktay K. Ovarian tissue cryopreservation and transplantation: preliminary findings and implications for cancer patients Human Reproduction Update 2001, 7: 526-534. PMID: 11727860, DOI: 10.1093/humupd/7.6.526.
- Spontaneous ovulation and menstruation following ovarian transplantation to the forearm.Oktay K, Rucinski J, Kliot G, Kan M, Rosenwaks Z. Spontaneous ovulation and menstruation following ovarian transplantation to the forearm. Fertility And Sterility 2001, 76: s75. DOI: 10.1016/s0015-0282(01)02230-0.
- Recent progress in oocyte and ovarian tissue cryopreservation and transplantationOktay K, Kan M, Rosenwaks Z. Recent progress in oocyte and ovarian tissue cryopreservation and transplantation Current Opinion In Obstetrics & Gynecology 2001, 13: 263-268. PMID: 11396648, DOI: 10.1097/00001703-200106000-00003.
- A technique for laparoscopic transplantation of frozen-banked ovarian tissueOktay K, Aydin B, Karlikaya G. A technique for laparoscopic transplantation of frozen-banked ovarian tissue Fertility And Sterility 2001, 75: 1212-1216. PMID: 11384651, DOI: 10.1016/s0015-0282(01)01776-9.
- Oocytes for late starters and posterity: are we on to something good or bad?Gosden R, Tan S, Oktay K. Oocytes for late starters and posterity: are we on to something good or bad? Fertility And Sterility 2000, 74: 1057. PMID: 11056263, DOI: 10.1016/s0015-0282(00)01574-0.
- Ovarian cryopreservation and transplantation: basic aspectsOktay K, Karlikaya G, Aydin B. Ovarian cryopreservation and transplantation: basic aspects Molecular And Cellular Endocrinology 2000, 169: 105-108. PMID: 11155939, DOI: 10.1016/s0303-7207(00)00361-0.
- Restoration of Ovarian Function After Autologous Transplantation of Human Ovarian Tissue in the ForearmOktay K, Aydin B, Economos K, Rucinski J. Restoration of Ovarian Function After Autologous Transplantation of Human Ovarian Tissue in the Forearm Fertility And Sterility 2000, 74: s90-s91. DOI: 10.1016/s0015-0282(00)00967-5.
- Interaction of Extracellular Matrix and Activin-A in the Initiation of Follicle Growth in the Mouse Ovary1Oktay K, Karlikaya G, Akman O, Ojakian G, Oktay M. Interaction of Extracellular Matrix and Activin-A in the Initiation of Follicle Growth in the Mouse Ovary1 Biology Of Reproduction 2000, 63: 457-461. PMID: 10906050, DOI: 10.1095/biolreprod63.2.457.
- The re-incarnation of an old question— clomid effect on oocyte and embryo?Oktay K, Berkowitz P, Berkus M, Schenken R, Brzyski R. The re-incarnation of an old question— clomid effect on oocyte and embryo? Fertility And Sterility 2000, 74: 422. PMID: 10970170, DOI: 10.1016/s0015-0282(00)00663-4.
- Ovarian Function after Transplantation of Frozen, Banked Autologous Ovarian TissueOktay K, Karlikaya G. Ovarian Function after Transplantation of Frozen, Banked Autologous Ovarian Tissue New England Journal Of Medicine 2000, 342: 1919. PMID: 10877641, DOI: 10.1056/nejm200006223422516.
- Transplantation of cryopreserved human ovarian tissue results in follicle growth initiation in SCID miceOktay K, Newton H, Gosden R. Transplantation of cryopreserved human ovarian tissue results in follicle growth initiation in SCID mice Fertility And Sterility 2000, 73: 599-603. PMID: 10689020, DOI: 10.1016/s0015-0282(99)00548-8.
- New Strategies in Studying Ovarian AgingOktay K, Karlikaya G, Bayrakceken A. New Strategies in Studying Ovarian Aging 2000, 80-88. DOI: 10.1007/978-0-387-21628-7_8.
- Ovarian tissue cryopreservation and transplantation techniquesBuyuk E, Oktay K. Ovarian tissue cryopreservation and transplantation techniques 2000, 69-76. DOI: 10.4324/9780203308516_chapter_6.
- Factoring in complexity and oocyte memory--can transformations and cyperpathology distort reality?Faddy M, Gosden R, Oktay K, Nelson J. Factoring in complexity and oocyte memory--can transformations and cyperpathology distort reality? Fertility And Sterility 1999, 71: 1170-2. PMID: 10360935.
- Development of human primordial follicles to antral stages in SCID/hpg mice stimulated with follicle stimulating hormone.Oktay K, Newton H, Mullan J, Gosden R. Development of human primordial follicles to antral stages in SCID/hpg mice stimulated with follicle stimulating hormone. Human Reproduction 1998, 13: 1133-1138. PMID: 9647533, DOI: 10.1093/humrep/13.5.1133.
- Cryopreservation of immature human oocytes and ovarian tissue: An emerging technology?Oktay K, Newton H, Aubard Y, Salha O, G.Gosden R. Cryopreservation of immature human oocytes and ovarian tissue: An emerging technology? Fertility And Sterility 1998, 69: 1-7. PMID: 9457923, DOI: 10.1016/s0015-0282(97)00207-0.
- Ontogeny of follicle-stimulating hormone receptor gene expression in isolated human ovarian follicles.Oktay K, Briggs D, Gosden R. Ontogeny of follicle-stimulating hormone receptor gene expression in isolated human ovarian follicles. The Journal Of Clinical Endocrinology & Metabolism 1997, 82: 3748-51. PMID: 9360535, DOI: 10.1210/jc.82.11.3748.
- Ontogeny of Follicle-Stimulating Hormone Receptor Gene Expression in Isolated Human Ovarian Follicles 1Oktay K, Briggs D, Gosden R. Ontogeny of Follicle-Stimulating Hormone Receptor Gene Expression in Isolated Human Ovarian Follicles 1 The Journal Of Clinical Endocrinology & Metabolism 1997, 82: 3748-3751. DOI: 10.1210/jcem.82.11.4346.
- O-019. Ovarian tissue bankingGosden R, Oktay K, Radford J, Rutherford A. O-019. Ovarian tissue banking Human Reproduction 1997, 12: 9-9. DOI: 10.1093/humrep/12.suppl_2.9.
- Isolation and characterization of primordial follicles from fresh and cryopreserved human ovarian tissueOktay K, Nugent D, Newton H, Salha O, Chatterjee P, Gosden R. Isolation and characterization of primordial follicles from fresh and cryopreserved human ovarian tissue Fertility And Sterility 1997, 67: 481-486. PMID: 9091334, DOI: 10.1016/s0015-0282(97)80073-8.
- Follicle freezing and autografting. A new method of medically assisted procreation?.Aubard Y, Newton H, Oktay K, Piver P, Gosden R. Follicle freezing and autografting. A new method of medically assisted procreation?. La Presse Médicale 1996, 25: 921-3. PMID: 8685154.
- Diminished α-inhibin messenger ribonucleic acid in in vitro fertilization-embryo transfer poor responders reflects declining follicle reserve**Presented at the 41st Annual Meeting of the Society for Gynecologic Investigation, Chicago, Illinois, March 22 to 26, 1994.Burns W, Oktay K, Tekmal R, Nelson J, Schenken R. Diminished α-inhibin messenger ribonucleic acid in in vitro fertilization-embryo transfer poor responders reflects declining follicle reserve**Presented at the 41st Annual Meeting of the Society for Gynecologic Investigation, Chicago, Illinois, March 22 to 26, 1994. Fertility And Sterility 1996, 65: 394-399. PMID: 8566269, DOI: 10.1016/s0015-0282(16)58106-0.
- Laparoscopic Treatment of Accessory Ureterocele in a Patient with Müllerian AplasiaOKTAY K, REYNA J, SCHENKEN R. Laparoscopic Treatment of Accessory Ureterocele in a Patient with Müllerian Aplasia Journal Of Gynecologic Surgery 1996, 12: 271-274. DOI: 10.1089/gyn.1996.12.271.
- Proliferating Cell Nuclear Antigen Marks the Initiation of Follicular Growth in the RatOktay K, Schenken R, Nelson J. Proliferating Cell Nuclear Antigen Marks the Initiation of Follicular Growth in the Rat Biology Of Reproduction 1995, 53: 295-301. PMID: 7492681, DOI: 10.1095/biolreprod53.2.295.
- Association of serum beta-hCG levels with myosalpingeal invasion and viable trophoblast mass in tubal pregnancy.Oktay K, Brzyski R, Miller E, Krugman D. Association of serum beta-hCG levels with myosalpingeal invasion and viable trophoblast mass in tubal pregnancy. Obstetrics And Gynecology 1994, 84: 803-6. PMID: 7524002.