Emmanuelle Schindler, MD, PhD
Assistant Professor; Medical Director, Headache Center of Excellence
Research & Publications
Biography
News
Coauthors
Selected Publications
- Case report: Psychedelic-induced seizures captured by intracranial electrocorticographyBlond B, Schindler E. Case report: Psychedelic-induced seizures captured by intracranial electrocorticography. Frontiers In Neurology 2023, 14: 1214969. PMID: 37456653, PMCID: PMC10343433, DOI: 10.3389/fneur.2023.1214969.
- Understanding headache classification coding within the veterans health administration using ICD-9-CM and ICD-10-CM in fiscal years 2014–2017Fodeh S, Fenton B, Wang R, Skanderson M, Altalib H, Kuruvilla D, Schindler E, Haskell S, Brandt C, Sico J. Understanding headache classification coding within the veterans health administration using ICD-9-CM and ICD-10-CM in fiscal years 2014–2017. PLOS ONE 2023, 18: e0279163. PMID: 36598881, PMCID: PMC9812322, DOI: 10.1371/journal.pone.0279163.
- The therapeutic potential of psychedelicsSchindler E, D'Souza D. The therapeutic potential of psychedelics. Science 2022, 378: 1051-1053. PMID: 36480624, DOI: 10.1126/science.abn5486.
- Exploratory investigation of a patient‐informed low‐dose psilocybin pulse regimen in the suppression of cluster headache: Results from a randomized, double‐blind, placebo‐controlled trialSchindler E, Sewell R, Gottschalk C, Luddy C, Flynn L, Zhu Y, Lindsey H, Pittman B, Cozzi N, D'Souza D. Exploratory investigation of a patient‐informed low‐dose psilocybin pulse regimen in the suppression of cluster headache: Results from a randomized, double‐blind, placebo‐controlled trial. Headache The Journal Of Head And Face Pain 2022, 62: 1383-1394. PMID: 36416492, DOI: 10.1111/head.14420.
- Recent advances in the diagnosis and management of cluster headacheSchindler EAD, Burish MJ. Recent advances in the diagnosis and management of cluster headache. The BMJ 2022, 376: e059577. PMID: 35296510, DOI: 10.1136/bmj-2020-059577.
- Cluster Headache: Clinical Characteristics and Opportunities to Enhance Quality of LifeGrinberg AS, Best RD, Min KM, Schindler EAD, Koo BB, Sico JJ, Seng EK. Cluster Headache: Clinical Characteristics and Opportunities to Enhance Quality of Life. Current Pain And Headache Reports 2021, 25: 65. PMID: 34668084, DOI: 10.1007/s11916-021-00979-8.
- Demoralization predicts suicidality in patients with cluster headacheKoo BB, Bayoumi A, Albanna A, Abusuliman M, Burrone L, Sico JJ, Schindler EAD. Demoralization predicts suicidality in patients with cluster headache. The Journal Of Headache And Pain 2021, 22: 28. PMID: 33879041, PMCID: PMC8056539, DOI: 10.1186/s10194-021-01241-7.
- “You will eat shoe polish if you think it would help”—Familiar and lesser‐known themes identified from mixed‐methods analysis of a cluster headache surveySchindler EAD, Cooper V, Quine DB, Fenton BT, Wright DA, Weil MJ, Sico JJ. “You will eat shoe polish if you think it would help”—Familiar and lesser‐known themes identified from mixed‐methods analysis of a cluster headache survey. Headache The Journal Of Head And Face Pain 2021, 61: 318-328. PMID: 33502769, DOI: 10.1111/head.14063.
- Exploratory Controlled Study of the Migraine-Suppressing Effects of PsilocybinSchindler EAD, Sewell RA, Gottschalk CH, Luddy C, Flynn LT, Lindsey H, Pittman BP, Cozzi NV, D’Souza D. Exploratory Controlled Study of the Migraine-Suppressing Effects of Psilocybin. Neurotherapeutics 2020, 18: 534-543. PMID: 33184743, PMCID: PMC8116458, DOI: 10.1007/s13311-020-00962-y.
- In an exploratory randomized, double-blind, placebo-controlled, cross-over study, psychoactive doses of intravenous delta-9-tetrahydrocannabinol fail to produce antinociceptive effects in healthy human volunteersSchindler EAD, Schnakenberg Martin AM, Sewell RA, Ranganathan M, DeForest A, Pittman BP, Perrino A, D’Souza D. In an exploratory randomized, double-blind, placebo-controlled, cross-over study, psychoactive doses of intravenous delta-9-tetrahydrocannabinol fail to produce antinociceptive effects in healthy human volunteers. Psychopharmacology 2020, 237: 3097-3107. PMID: 32632491, DOI: 10.1007/s00213-020-05595-9.
- Pharmacological, physiological, and familial factors in propranolol-induced visionsSchindler EAD. Pharmacological, physiological, and familial factors in propranolol-induced visions. Neurology Clinical Practice 2019, 10: e25-e26. PMID: 32612878, PMCID: PMC7292560, DOI: 10.1212/cpj.0000000000000698.
- Survey Analysis of the Use, Effectiveness, and Patient‐Reported Tolerability of Inhaled Oxygen Compared With Injectable Sumatriptan for the Acute Treatment of Cluster HeadacheSchindler EAD, Wright DA, Weil MJ, Gottschalk CH, Pittman BP, Sico JJ. Survey Analysis of the Use, Effectiveness, and Patient‐Reported Tolerability of Inhaled Oxygen Compared With Injectable Sumatriptan for the Acute Treatment of Cluster Headache. Headache The Journal Of Head And Face Pain 2018, 58: 1568-1578. PMID: 30221765, DOI: 10.1111/head.13405.
- Neuroendocrine Associations Underlying the Persistent Therapeutic Effects of Classic Serotonergic PsychedelicsSchindler EAD, Wallace RM, Sloshower JA, D’Souza D. Neuroendocrine Associations Underlying the Persistent Therapeutic Effects of Classic Serotonergic Psychedelics. Frontiers In Pharmacology 2018, 9: 177. PMID: 29545753, PMCID: PMC5838010, DOI: 10.3389/fphar.2018.00177.
- Neuropsychiatric Presentation of Wilson Disease in an Adolescent MaleSchindler EA, Guo XM, Schrag M, Ghoshal S, Schilsky ML, Beslow LA. Neuropsychiatric Presentation of Wilson Disease in an Adolescent Male. Neuropediatrics 2016, 47: 346-347. PMID: 27490186, DOI: 10.1055/s-0036-1586225.
- Indoleamine Hallucinogens in Cluster Headache: Results of the Clusterbusters Medication Use SurveySchindler EA, Gottschalk CH, Weil MJ, Shapiro RE, Wright DA, Sewell RA. Indoleamine Hallucinogens in Cluster Headache: Results of the Clusterbusters Medication Use Survey. Journal Of Psychoactive Drugs 2015, 47: 372-381. PMID: 26595349, DOI: 10.1080/02791072.2015.1107664.
- Clonidine Abuse in a Methadone-Maintained, Clonazepam-Abusing PatientSchindler EA, Tirado-Morales DJ, Kushon D. Clonidine Abuse in a Methadone-Maintained, Clonazepam-Abusing Patient. Journal Of Addiction Medicine 2013, 7: 218-219. PMID: 23519051, DOI: 10.1097/adm.0b013e31828ab8d4.
- Phospholipase C mediates (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-, but not lysergic acid diethylamide (LSD)-elicited head bobs in rabbit medial prefrontal cortexSchindler EA, Harvey JA, Aloyo VJ. Phospholipase C mediates (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-, but not lysergic acid diethylamide (LSD)-elicited head bobs in rabbit medial prefrontal cortex. Brain Research 2012, 1491: 98-108. PMID: 23123701, PMCID: PMC3559188, DOI: 10.1016/j.brainres.2012.10.057.
- Serotonergic and dopaminergic distinctions in the behavioral pharmacology of (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD)Schindler EA, Dave KD, Smolock EM, Aloyo VJ, Harvey JA. Serotonergic and dopaminergic distinctions in the behavioral pharmacology of (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Pharmacology Biochemistry And Behavior 2011, 101: 69-76. PMID: 22197710, PMCID: PMC3272148, DOI: 10.1016/j.pbb.2011.12.002.
- Intrahippocampal LSD accelerates learning and desensitizes the 5-HT2A receptor in the rabbit, Romano et al.Romano AG, Quinn JL, Li L, Dave KD, Schindler EA, Aloyo VJ, Harvey JA. Intrahippocampal LSD accelerates learning and desensitizes the 5-HT2A receptor in the rabbit, Romano et al. Psychopharmacology 2010, 212: 441-448. PMID: 20827462, DOI: 10.1007/s00213-010-2004-7.
- Relationship between recovery of frontocortical 5HT2A receptor density and PI hydrolysis after chronic treatmentSchindler E, Aloyo V, Harvey J. Relationship between recovery of frontocortical 5HT2A receptor density and PI hydrolysis after chronic treatment. The FASEB Journal 2008, 22: 621-621. DOI: 10.1096/fasebj.22.2_supplement.621.
Clinical Trials
| Conditions | Study Title |
|---|---|
| Diseases of the Nervous System; Mental Health & Behavioral Research; Pain Control | Effects of Psilocybin in Concussion Headache |
| Headaches | Repeat Dosing of Psilocybin in Migraine Headache |