2023
Identification of risk factors and mosquito vectors associated with dengue virus infection in American Samoa, 2017
Sharp T, Tufa A, Cotter C, Lozier M, Santiago G, Johnson S, Mataia’a M, Waterman S, Muñoz-Jordán J, Paz-Bailey G, Hemme R, Schmaedick M, Anesi S. Identification of risk factors and mosquito vectors associated with dengue virus infection in American Samoa, 2017. PLOS Global Public Health 2023, 3: e0001604. PMID: 37418355, PMCID: PMC10328243, DOI: 10.1371/journal.pgph.0001604.Peer-Reviewed Original ResearchDENV infectionIgM ELISARisk factorsRT-PCRDENV-2Dengue virus infectionPopulation-specific risk factorsFrequency of infectionDENV nucleic acidMosquito vectorsOutbreak of dengueCluster investigationsFebrile illnessMedian ageResidents of householdsRole of AeDengue patientsVirus infectionDENV transmissionSerum specimensZika virusPatient specimensBivariate analysisInfectionAdult female mosquitoes
2021
Knowledge gaps in the epidemiology of severe dengue impede vaccine evaluation
Sharp T, Anderson K, Katzelnick L, Clapham H, Johansson M, Morrison A, Harris E, Paz-Bailey G, Waterman S. Knowledge gaps in the epidemiology of severe dengue impede vaccine evaluation. The Lancet Infectious Diseases 2021, 22: e42-e51. PMID: 34265259, PMCID: PMC11379041, DOI: 10.1016/s1473-3099(20)30871-9.Peer-Reviewed Original ResearchConceptsDengue virus infectionSevere dengueVirus infectionDisease severityAnti-dengue virus antibodiesMajor organ failureHospital admissionOrgan failureVaccine evaluationClinical spectrumVaccine trialsPrevious infectionRisk factorsVirus antibodiesClinical studiesClinical practiceDengue virusStudy participantsInfectionLack of specificityHost factorsVirus characteristicsDengueEpidemiologyRange of ages
2017
Risk Factors Associated with Persistence of Zika Virus Nucleic Acid in Serum and Semen
Lozier M, Rosenberg E, Doyle K, Adams L, Klein L, Muñoz-Jordan J, Alvarado L, Sharp T, Paz-Bailey G. Risk Factors Associated with Persistence of Zika Virus Nucleic Acid in Serum and Semen. Open Forum Infectious Diseases 2017, 4: s56-s57. PMCID: PMC5632286, DOI: 10.1093/ofid/ofx162.133.Peer-Reviewed Original ResearchDetectable ZIKV RNADays post-symptom onsetLonger median timeNon-pregnant womenZIKV RNAPregnant womenSymptom onsetMedian timeStudy participationRT-PCRPost-symptom onsetDuration of detectionRT-PCR testingZika virus RNAProportion of menVirus nucleic acidZika virus nucleic acidProspective cohortPrevention recommendationsRisk factorsIndex caseDiagnostic testingFirst monthConjunctivitisSerum