Skip to Main Content

Anton Bennett, PhD

Dorys McConnell Duberg Professor of Pharmacology and Professor of Comparative Medicine
DownloadHi-Res Photo

Additional Titles

Director, Yale Center for Molecular and Systems Metabolism (YMSM)

Director of Diversity and Inclusion, Yale Combined Program in the Biological and Biomedical Sciences (BBS)

About

Titles

Dorys McConnell Duberg Professor of Pharmacology and Professor of Comparative Medicine

Director, Yale Center for Molecular and Systems Metabolism (YMSM); Director of Diversity and Inclusion, Yale Combined Program in the Biological and Biomedical Sciences (BBS)

Appointments

Education & Training

Postdoc
Cold Spring Harbor Laboratories (1998)
Postdoc
Harvard Medical School (1995)
PhD
New York Medical College (1993)

Research

Overview

Cell proliferation, cell differentiation and death are controlled by signaling pathways that are mediated by protein tyrosyl phosphorylation. The net cellular level of protein tyrosyl phosphorylation is regulated by the intrinsic and opposing activities of protein tyrosine kinases and protein tyrosine phosphatases (PTPs). Dysregulation of the net level of tyrosyl phosphorylation causes cancer, diabetes, cardiovascular disease and developmental abnormalities.

We focus our studies on how PTPs regulate cell signaling by controlling protein tyrosyl dephosphorylation. We are also exploring how PTPs participate in the pathogenesis of diseases such as obesity and diabetes, cardiovascular disease and developmental abnormalities. These research efforts are being accomplished by using integrated approaches that encompass cell biology, genetics, protein biochemistry, cell imaging and animal models. Our long-term research goals are to uncover the function of PTPs in order to identify whether these enzymes might serve as novel therapeutic targets for the treatment of human diseases.

For further information please visit the Bennett Lab website - Home | Bennett Lab (bennett-lab.org)

Medical Subject Headings (MeSH)

Cardiovascular Diseases; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Neurosciences; Nutritional and Metabolic Diseases; Signal Transduction

Research at a Glance

Yale Co-Authors

Frequent collaborators of Anton Bennett's published research.

Publications

2024

2023

2022

Academic Achievements & Community Involvement

  • honor

    Blavatnik Innovation Award

  • honor

    Burroughs-Wellcome Award for New Investigators in Pharmacology

  • honor

    Pharmaceuticals Manufacturers Association Young Investigators Award

Get In Touch